# COSRX The Vitamin C 13 Serum for mature skin

**Lovi Fit: High fit for mature skin.**
Normal Skin Fit: High · Effectiveness: High · Safety: High.

Page: https://lovi.care/skincare/ae/p/cosrx/the-vitamin-c-13-serum/for/mature-skin

The Lovi Fit is the same in every country; only the stores and prices differ, and the ones here are for the United Arab Emirates.

Brand: [COSRX](https://lovi.care/skincare/ae/brands/cosrx)
Category: [Serums and treatments](https://lovi.care/skincare/ae/best/serums)

This fit is calculated for the concerns frequently associated with mature skin: fine lines, wrinkles, and loss of firmness. For scores based on a full skin profile (12D face scan, goals, preferences), use the Lovi app.

A great choice for mature skin; a few serums fit it even better.

## Why this fit

- Highly suitable for your normal skin, this serum effectively targets wrinkles and fine lines with ascorbic acid and adenosine, promoting collagen production and skin elasticity. The combination of ascorbic acid and 3-0-ethyl ascorbic acid offers excellent brightening and evening of skin tone for visible anti-aging effects.
- Tocopherol and squalane provide antioxidant activity and support collagen synthesis, further enhancing the benefits for your skin.
- The product has a favorable safety profile with no risks of irritation due to the absence of prohibited or harsh ingredients.

## Fit by skin type

- [Oily skin](https://lovi.care/skincare/ae/p/cosrx/the-vitamin-c-13-serum/for/oily-skin): High
- [Dry skin](https://lovi.care/skincare/ae/p/cosrx/the-vitamin-c-13-serum/for/dry-skin): High
- [Combination skin](https://lovi.care/skincare/ae/p/cosrx/the-vitamin-c-13-serum/for/combination-skin): High
- [Sensitive skin](https://lovi.care/skincare/ae/p/cosrx/the-vitamin-c-13-serum/for/sensitive-skin): High
- [Acne-prone skin](https://lovi.care/skincare/ae/p/cosrx/the-vitamin-c-13-serum/for/acne-prone-skin): High
- [Skin with dark spots](https://lovi.care/skincare/ae/p/cosrx/the-vitamin-c-13-serum/for/dark-spots): Average
- [Mature skin](https://lovi.care/skincare/ae/p/cosrx/the-vitamin-c-13-serum/for/mature-skin): High (this page)
- [Dry sensitive skin](https://lovi.care/skincare/ae/p/cosrx/the-vitamin-c-13-serum/for/dry-sensitive-skin): High
- [Oily acne-prone skin](https://lovi.care/skincare/ae/p/cosrx/the-vitamin-c-13-serum/for/oily-acne-prone-skin): High

## Key ingredients

Ascorbic Acid, Sodium Hyaluronate, Super Vitamin E, Glutathione, Niacinamide

## What the research says

- A topical serum containing vitamin C, vitamin E, and raspberry leaf cell culture extract improved skin color, elasticity, radiance, smoothness, scaliness, and wrinkles compared to the untreated contralateral side in fifty female volunteers. ([Journal of Cosmetic Dermatology, 2020](https://pubmed.ncbi.nlm.nih.gov/31975502/))
- Topical application of a vitamin C-squalene bioconjugate significantly increased epidermal thickness, type III collagen production, and glycosaminoglycans production in human skin explants compared to free vitamin C and vitamin C-palmitate. ([Scientific Reports, 2020](https://pubmed.ncbi.nlm.nih.gov/33037252/))
- Topical oxidized glutathione significantly decreases the skin melanin index and improves moisture content, smoothness, wrinkle formation, and elasticity compared to placebo in healthy women. ([Clinical, Cosmetic and Investigational Dermatology, 2014](https://pubmed.ncbi.nlm.nih.gov/25378941/))
- Topical post-laser application of human adipocyte-derived mesenchymal stem cell media combined with niacinamide significantly improved wrinkle index, melanin index, patient satisfaction, and investigator esthetic improvement scores compared to vehicle cream in patients with aging skin. ([Journal of Cosmetic Dermatology, 2021](https://pubmed.ncbi.nlm.nih.gov/33103316/))
- Treatment with a combination of niacinamide and hyaluronic acid improved skin aging signs and demonstrated a senomorphic effect by decreasing SASP and autocrine signaling genes in women. ([Scientific Reports, 2024](https://pubmed.ncbi.nlm.nih.gov/39009698/))
- Topical application of 5% vitamin C cream significantly improved global clinical scores, increased skin microrelief density, and induced elastic tissue repair in photoaged skin compared to excipient control in healthy female volunteers. ([Experimental Dermatology, 2003](https://pubmed.ncbi.nlm.nih.gov/12823436/))
- Ascorbic acid 2-glucoside gel significantly reduced gingival melanin pigmentation after 4 weeks compared to placebo in 73 subjects with symmetric pigmentation. ([Journal of Periodontology, 2009](https://pubmed.ncbi.nlm.nih.gov/19186973/))
- Topical application of VC-IP cream twice daily for 8 weeks reduces periorbital wrinkles in female subjects compared to a placebo cream. ([Journal of Cosmetic Dermatology, 2022](https://pubmed.ncbi.nlm.nih.gov/34910367/))
- Topical application of 0.1% hyaluronic acid formulations of different molecular weights led to significant improvements in skin hydration and elasticity, with low-molecular-weight formulations also significantly reducing wrinkle depth in seventy-six female subjects compared to a vehicle control. ([Journal of Drugs in Dermatology, 2011](https://pubmed.ncbi.nlm.nih.gov/22052267/))
- Topical application of hyaluronic acid in conjunction with free gingival graft significantly reduced donor site postoperative pain until day 7 compared to normal saline, with no significant differences in graft dimensions or patient satisfaction. ([Clinical Oral Investigations, 2022](https://pubmed.ncbi.nlm.nih.gov/34623507/))
- Treatment with a hyaluronic acid-containing mouth rinse or topical gel led to significant lesion reduction, pain relief, and normalization of lesion color in adult patients with minor recurrent aphthous stomatitis, with the gel formulation showing an earlier healing onset at 3 days. ([BMC Oral Health, 2019](https://pubmed.ncbi.nlm.nih.gov/31311529/))
- Topical application of an antioxidant serum containing 15% ascorbic acid, 0.5% ferulic acid, and 1% tocopherol prevented particulate matter-induced degradation of extracellular matrix components, inflammation, and oxidative stress in the skin of 15 female volunteers compared to untreated controls. ([Journal of Cosmetic Dermatology, 2025](https://pubmed.ncbi.nlm.nih.gov/40642809/))
- Dermatological products containing d-alpha tocopheryl acetate showed non-comedogenic potential with less than a 50% increase in microcomedones in 12 healthy male subjects compared to octyl palmitate. ([Contemporary Clinical Trials Communications, 2021](https://pubmed.ncbi.nlm.nih.gov/34471722/))
- Topical application of an antioxidant mix containing 15% ascorbic acid, 0.5% ferulic acid, and 1% tocopherol prevented PM and UV-induced skin barrier perturbation, lipid peroxidation, inflammatory markers, MMP9 activation, and Type I collagen loss in 15 healthy females compared to untreated exposed skin. ([Journal of Cosmetic Dermatology, 2024](https://pubmed.ncbi.nlm.nih.gov/38590207/))
- Glutathione amino acid precursors effectively increase cellular glutathione levels, reducing oxidative stress, ATP depletion, and DNA damage in human keratinocytes, clinical subjects, and ex vivo skin compared to controls. ([Journal of the European Academy of Dermatology and Venereology, 2024](https://pubmed.ncbi.nlm.nih.gov/38189670/))
- Topical glutathione improves hyperpigmentation, reduces ultraviolet-induced erythema and wrinkles, decreases transepidermal water loss, and enhances antioxidant capacity. ([The Journal of Clinical and Aesthetic Dermatology, 2025](https://pubmed.ncbi.nlm.nih.gov/41416233/))
- RayGel reduced skin reaction severity with a lower average score of 93.7 compared to 123.3 for the placebo group in patients undergoing whole breast external-beam irradiation. ([American Journal of Surgery, 2005](https://pubmed.ncbi.nlm.nih.gov/15862509/))
- Topical nicotinamide prevented solar-simulated UV-induced immunosuppression in healthy volunteers, and men experienced immunosuppression at solar-simulated UV doses three times lower than those required for women. ([The Journal of Investigative Dermatology, 2008](https://pubmed.ncbi.nlm.nih.gov/17882270/))
- Topical 5% niacinamide applied twice daily for 12 weeks reduced fine lines and wrinkles, hyperpigmented spots, red blotchiness, and skin sallowness, and improved skin elasticity compared to vehicle control in 50 female white subjects with facial photoaging. ([Dermatologic Surgery, 2005](https://pubmed.ncbi.nlm.nih.gov/16029679/))
- Topical 2% niacinamide significantly decreased sebum excretion rate in Japanese individuals and casual sebum levels in Caucasian individuals compared to placebo or baseline. ([Journal of Cosmetic and Laser Therapy, 2006](https://pubmed.ncbi.nlm.nih.gov/16766489/))

## What reviewers say

This serum is a gentle and effective option for sensitive and acne-prone skin, frequently praised for its ability to brighten the complexion and fade dark spots without causing irritation. Users often note a hydrating and plumping effect, though a significant number find the strong, fishy scent and sticky finish to be considerable drawbacks. Some also mention the need for refrigeration due to the formula's instability and occasional packaging issues.

- Liked: Gentle formula (mostly mentioned)
- Liked: Brightens skin (often mentioned)
- Disliked: Unpleasant scent (often mentioned)
- Liked: Good value (sometimes noted)
- Liked: Hydrating and plumping (sometimes noted)
- Disliked: Sticky finish (sometimes noted)
- Disliked: Storage requirements (sometimes noted)
- Disliked: Packaging issues (rarely noted)

## How to apply

- Use this serum in your PM routine. Start by applying it 3 times a week, and work up to daily use if your skin likes it.
- Apply this serum after your toner and before your moisturizer.
- Gently press 2-3 drops of the serum into your skin and let it absorb for a minute.
- You can apply the serum on dry skin for the best results against fine lines.
- Always do a patch test before your first use and avoid the sensitive eye area.
- Video: https://storage.pora.ai/c879dda8655a61c19d3d8c9ebad6b06d.mp4

## Questions and answers

### What makes COSRX Vitamin C 13 a great fit for mature skin?

This serum is a great fit because ascorbic acid and adenosine help smooth out wrinkles while boosting firmness. Additionally, vitamin E and squalane provide antioxidant support, and ascorbic acid together with 3-o-ethyl ascorbic acid helps brighten dark spots and even out your skin tone.
Sources: [Clinical, Cosmetic and Investigational Dermatology, 2014](https://pubmed.ncbi.nlm.nih.gov/25378941/), [Journal of Cosmetic Dermatology, 2020](https://pubmed.ncbi.nlm.nih.gov/31975502/)

### Which ingredients make this serum a good fit for mature skin?

This serum is a great fit for mature skin because it contains ascorbic acid and adenosine to smooth fine lines, along with tocopherol and squalane to support firmness. It also includes niacinamide and glutathione to help even out your skin tone and boost radiance.
Sources: [Clinical, Cosmetic and Investigational Dermatology, 2014](https://pubmed.ncbi.nlm.nih.gov/25378941/), [Journal of Cosmetic Dermatology, 2020](https://pubmed.ncbi.nlm.nih.gov/31975502/)

### What does Vitamin C do for mature skin?

Vitamin C helps mature skin by smoothing out wrinkles, brightening dark spots, and boosting firmness. It works by encouraging collagen production to keep skin looking youthful and radiant.
Sources: [Journal of Cosmetic Dermatology, 2020](https://pubmed.ncbi.nlm.nih.gov/31975502/)

### What does Hyaluronic Acid do for mature skin?

Hyaluronic acid helps mature skin by deeply boosting moisture, improving elasticity, and smoothing the appearance of fine lines and wrinkles. Regular use keeps the skin looking plump and soft while supporting overall firmness and hydration.
Sources: [Journal of Drugs in Dermatology, 2011](https://pubmed.ncbi.nlm.nih.gov/22052267/), [Skin Research and Technology, 2024](https://pubmed.ncbi.nlm.nih.gov/38591218/)

### Where does this serum go in a skincare routine for mature skin?

This serum goes in the evening routine after your cleansing toner and before your moisturizer. Putting it in the evening helps keep your routine simple and adds extra safety around sun exposure.

### Can I use this serum with retinol, and in what order?

You can use this serum with retinol by applying this vitamin C in the morning and your retinol at night to keep your skin calm and avoid irritation. Using them on alternate nights or waiting a few minutes between layers also helps if your skin is sensitive.
Sources: [Journal of Cosmetic Dermatology, 2020](https://pubmed.ncbi.nlm.nih.gov/31975502/)

### How often should I use this serum?

This treatment is put in your evening routine once a day for simplicity and extra safety around sun exposure, though some serums with actives may also be used in the morning or twice a day. It has a favorable safety profile with no risks of irritation.
Sources: [Journal of Cosmetic Dermatology, 2020](https://pubmed.ncbi.nlm.nih.gov/31975502/), [Facial Plastic Surgery, 2014](https://pubmed.ncbi.nlm.nih.gov/24488631/)

### Can this serum clog pores, cause breakouts or purging for mature skin?

This serum is unlikely to clog pores or cause breakouts for mature skin since it has a safe formula without harsh ingredients. It helps smooth fine lines and brighten your tone while keeping your skin calm.
Sources: [Clinical, Cosmetic and Investigational Dermatology, 2014](https://pubmed.ncbi.nlm.nih.gov/25378941/), [Journal of Cosmetic Dermatology, 2020](https://pubmed.ncbi.nlm.nih.gov/31975502/)

### Is this serum fragrance-free and alcohol-free?

Yes, it has no fragrance and no drying alcohol.

## Alternatives for mature skin

- [Paula's Choice RESIST Super Antioxidant Concentrate Serum](https://lovi.care/skincare/ae/p/paula-s-choice/resist-super-antioxidant-concentrate-serum/for/mature-skin) — Superior fit — AED 347.75 at Amazon
- [SkinCeuticals C E Ferulic](https://lovi.care/skincare/ae/p/skinceuticals/c-e-ferulic/for/mature-skin) — Superior fit — AED 715.99 at Amazon
- [NEOGEN DERMALOGY REAL VITA C SERUM](https://lovi.care/skincare/ae/p/neogen-dermalogy/real-vita-c-serum/for/mature-skin) — High fit — AED 89.30 at Amazon

## Pairs well with

- Cleanser: [Fresh Soy Face Cleanser](https://lovi.care/skincare/ae/p/fresh/soy-face-cleanser/for/mature-skin) — Superior fit — AED 84.53 at Amazon
- Hydrating Toner: [COSRX Propolis Synergy Toner](https://lovi.care/skincare/ae/p/cosrx/full-fit-propolis-synergy-toner/for/mature-skin) — Superior fit — AED 65.43 at Amazon
- Moisturizer: [Elizabeth Arden Ceramide Lift and Firm Night Cream](https://lovi.care/skincare/ae/p/elizabeth-arden/advanced-ceramide-lift-and-firm-night-cream/for/mature-skin) — Superior fit — AED 493.00 at Amazon

## Where to buy

- Amazon.ae: AED 92.00 (https://www.amazon.ae/dp/B0BS8M8Q5L?tag=lovi00-21&linkCode=osi&th=1&psc=1)
Prices checked 6 Nov 2026.

## Ingredients

Water, Ascorbic Acid, Butylene Glycol, Dipropylene Glycol, Tromethamine, 3-0-Ethyl Ascorbic Acid, Panthenol, Acetyl Glucosamine, Caffeine, Sodium Hyaluronate, Sodium Sulfite, Disodium Edta, Glutathione, Adenosine, Gardenia Florida Fruit Extract, Allantoin, Dextrin, Squalane, Tocotrienols, Tocopherol, Palm Oil, Arginine, Niacinamide, Pentylene Glycol, Glycyrrhiza Glabra Root Extract Licorice Root Extract
## About the Lovi Fit

Lovi: Unbiased, science-based skincare AI trained on real user outcomes.

Lovi calculates every fit score from the full ingredient list with brand-independent rules its dermatologists and cosmetic chemists build and review, and personalizes every pick with AI trained on the real results of millions of users. Lovi trains its fit score models on a proprietary dataset built from more than 10,000 expert-labeled products and more than 100,000 simulated examples, following an internally consistent methodology presented at Cosmoprof, AMWC, and Skin of Color Update. Levels from best to worst: Superior, High, Average, Low, Caution, Warning.

Behind this fit score: Nadia Kapleva, MS (Co-founder, Medical Director); Alexey Shagraev, PhD (Co-founder, CEO and CTO); Dr. Sofía Perea Pérez, MD, MSc (Medical Board); Aishani Shah, MD (Medical Board); Asya Zubkova, MS (Medical Board); Hanna Kurets, MD (Medical Board, Medical Advisor); Elina Nazarenko, MD (Medical Board); Victoria Derkova, MS (Medical Board).

Page built Nov 8, 2026.

More from Lovi: https://lovi.care/skincare/llms.txt

## This page in other countries

- United States: https://lovi.care/skincare/p/cosrx/the-vitamin-c-13-serum/for/mature-skin
- United Kingdom: https://lovi.care/skincare/uk/p/cosrx/the-vitamin-c-13-serum/for/mature-skin
- Ireland: https://lovi.care/skincare/ie/p/cosrx/the-vitamin-c-13-serum/for/mature-skin
- Germany: https://lovi.care/skincare/de/p/cosrx/the-vitamin-c-13-serum/for/mature-skin
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- Italy: https://lovi.care/skincare/it/p/cosrx/the-vitamin-c-13-serum/for/mature-skin
- Netherlands: https://lovi.care/skincare/nl/p/cosrx/the-vitamin-c-13-serum/for/mature-skin
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- Canada: https://lovi.care/skincare/ca/p/cosrx/the-vitamin-c-13-serum/for/mature-skin
- Australia: https://lovi.care/skincare/au/p/cosrx/the-vitamin-c-13-serum/for/mature-skin
- Singapore: https://lovi.care/skincare/sg/p/cosrx/the-vitamin-c-13-serum/for/mature-skin
- Saudi Arabia: https://lovi.care/skincare/sa/p/cosrx/the-vitamin-c-13-serum/for/mature-skin
- United Arab Emirates: https://lovi.care/skincare/ae/p/cosrx/the-vitamin-c-13-serum/for/mature-skin (this page)