Clarins Total Eye Lift for skin with dark spots

Questions and answers

What the research says

• Treatment of immortalized human keratinocytes with Acetyl Tetrapeptide-2 increased cell stiffness across its concentration range, while Acetyl Hexapeptide-50 increased stiffness at 0.05 µg/ml but decreased it at 0.5 and 5 µg/ml compared to untreated controls.

  International Journal of Peptide Research and Therapeutics, 2018

• Topical dexpanthenol acts as a moisturizer, improves stratum corneum hydration, accelerates wound healing and epidermal regeneration, reduces erythema, and improves symptoms of skin irritation compared to vehicle or no pretreatment.

  American Journal of Clinical Dermatology, 2002

• A new topical panthenol-containing emollient significantly improved transepidermal water loss reduction, stratum corneum hydration, and intercellular lipid lamellae length compared with control in healthy subjects without negatively impacting bacterial viability.

  The Journal of Dermatological Treatment, 2017

• A panthenol-enriched mask significantly decreased erythema and hyperpigmentation, increased sebum and stratum corneum moisture, and reduced transepidermal water loss compared to a saline dressing in 60 subjects undergoing facial laser treatment.

  Journal of Cosmetic Dermatology, 2025

• A topical cosmetic slimming product containing tetrahydroxypropyl ethylenediamine, caffeine, carnitine, forskolin and retinol significantly reduced body circumferences and improved skin aspect compared with placebo in 78 women over 12 weeks.

  International Journal of Cosmetic Science, 2011

• Topical sunscreen formulations containing caffeine combined with UV filters increased in vivo anti-UVB protection by approximately 25% and showed higher SPF values compared to caffeine-free sunscreen, while being well tolerated by the skin of healthy subjects.

  Frontiers in Physiology, 2019

• Caffeine gel combined with choline geranate showed high skin permeation capacity and superior clinical results in cellulite treatment compared to caffeine gel without ionic liquid.

  AAPS PharmSciTech, 2021

• A combination cream of stimu-tex AS and saccharide isomerate reduced erythema, increased skin capacitance, and reduced transepidermal water loss compared to placebo in 20 subjects after fractional CO2 laser procedure without causing serious adverse events.

  Lasers in Medical Science, 2025

• A skin barrier restoring cream with shea butter, silkflo, and vitamin E increased type I procollagen synthesis, enhanced antioxidant enzyme activity, decreased reactive oxygen species generation, and promoted hyaluronic acid production in H2O2-stimulated human keratinocyte cells compared to untreated cells.

  International Journal of Cosmetic Science, 2025

• Topical escin promotes angiogenic behavior and enhances adenosine-induced perfusion in humans by activating Wnt signaling via Gsk3beta down-regulation.

  Current Issues in Molecular Biology, 2025

• External use of escin reduced acute and chronic cutaneous inflammation and edema in rat and mouse models by down-regulating PGE2, TNF-α, and IL-1β, promoting glucocorticoid receptor expression, and inhibiting NF-κB and AP-1 expressions.

  Chinese Journal of Natural Medicines, 2018

Ingredients

Water, Glycerin, Caprylic Capric Triglyceride, Propanediol, Cetearyl Alcohol, Betaine, Hydrogenated Coco-Glycerides, Panthenol, Glyceryl Stearate, Peg-100 Stearate, Pentylene Glycol, Butyrospermum Parkii Butter Shea Butter, Cetearyl Glucoside, Albizia Julibrissin Bark Extract, Acacia Farnesiana Wax Flower, Caffeine, Steareth-21, Dimethicone, Carbomer, Chlorphenesin, Ethylhexylglycerin, Tocopheryl Acetate, Ci 77891 Titanium Dioxide, Synthetic Fluorphlogopite, Disodium Edta, Escin, Parfum, Butylene Glycol, Dimethiconol, Sodium Hydroxide, Alcohol, Harungana Madagascariensis Extract, Olea Europaea Fruit Extract Olive Fruit Extract, Paullinia Cupana Seed Extract, Sodium Benzoate, Tin Oxide, Acetyl Tetrapeptide-2, Dextran

Behind this fit score

Lovi calculates every fit score from the full ingredient list with brand-independent rules our dermatologists and cosmetic chemists build and review, and personalizes every pick with AI trained on the real results of millions of users. Lovi trains its fit score models on a proprietary dataset built from more than 10,000 expert-labeled products and more than 100,000 simulated examples, following an internally consistent methodology presented at Cosmoprof, AMWC, and Skin of Color Update.