# Cetaphil Ceramide Serum for sensitive skin

**Lovi Fit: Average fit for sensitive skin.**
Normal Skin Fit: Superior · Effectiveness: High · Safety: High.

Page: https://lovi.care/skincare/ae/p/cetaphil/ceramide-serum/for/sensitive-skin

The Lovi Fit is the same in every country; only the stores and prices differ, and the ones here are for the United Arab Emirates.

Brand: [Cetaphil](https://lovi.care/skincare/ae/brands/cetaphil)
Category: [Moisturizers and moisturizing serums](https://lovi.care/skincare/ae/best/moisturizers)

This fit is calculated for the concerns frequently associated with sensitive skin: redness, stinging, and reactions to new products. For scores based on a full skin profile (12D face scan, goals, preferences), use the Lovi app.

Works for sensitive skin; other moisturizers fit it better.

## Why this fit

- Offers moderate benefits for your redness and irritation, as glycerin, hyaluronic acid, and panthenol provide supportive hydration and soothing effects for your normal skin. Ceramides (NP, AP, EOP), cholesterol, and hyaluronic acid in moderate concentrations enhance skin barrier function and offer excellent moisturizing.
- The formulation is safe for your sensitive skin due to the absence of harsh ingredients and the inclusion of allantoin and panthenol for calming.
- This product is generally safe for your sensitive skin, as it lacks prohibited or harsh ingredients and contains soothing components like allantoin and panthenol.

## Fit by skin type

- [Oily skin](https://lovi.care/skincare/ae/p/cetaphil/ceramide-serum/for/oily-skin): High
- [Dry skin](https://lovi.care/skincare/ae/p/cetaphil/ceramide-serum/for/dry-skin): High
- [Combination skin](https://lovi.care/skincare/ae/p/cetaphil/ceramide-serum/for/combination-skin): High
- [Sensitive skin](https://lovi.care/skincare/ae/p/cetaphil/ceramide-serum/for/sensitive-skin): Average (this page)
- [Acne-prone skin](https://lovi.care/skincare/ae/p/cetaphil/ceramide-serum/for/acne-prone-skin): Superior
- [Skin with dark spots](https://lovi.care/skincare/ae/p/cetaphil/ceramide-serum/for/dark-spots): High
- [Mature skin](https://lovi.care/skincare/ae/p/cetaphil/ceramide-serum/for/mature-skin): High
- [Dry sensitive skin](https://lovi.care/skincare/ae/p/cetaphil/ceramide-serum/for/dry-sensitive-skin): High
- [Oily acne-prone skin](https://lovi.care/skincare/ae/p/cetaphil/ceramide-serum/for/oily-acne-prone-skin): High

## Key ingredients

Ceramides, Hyaluronic Acid, Glycerin, Phytosphingosine, Cholesterol

## What the research says

- Topical dexpanthenol acts as a moisturizer, improves stratum corneum hydration, accelerates wound healing and epidermal regeneration, reduces erythema, and improves symptoms of skin irritation compared to vehicle or no pretreatment. ([American Journal of Clinical Dermatology, 2002](https://pubmed.ncbi.nlm.nih.gov/12113650/))
- A single application of a moisturizing fluid containing hyaluronic acid 1%, glycerin 5%, and Centella asiatica stem cells extract significantly increased skin hydration by 29% and reduced transepidermal water loss at 24 hours compared to baseline and an untreated control site in twenty healthy women. ([Clinical, Cosmetic and Investigational Dermatology, 2017](https://pubmed.ncbi.nlm.nih.gov/28860834/))
- A new topical panthenol-containing emollient significantly improved transepidermal water loss reduction, stratum corneum hydration, and intercellular lipid lamellae length compared with control in healthy subjects without negatively impacting bacterial viability. ([The Journal of Dermatological Treatment, 2017](https://pubmed.ncbi.nlm.nih.gov/27425824/))
- A panthenol-enriched mask significantly decreased erythema and hyperpigmentation, increased sebum and stratum corneum moisture, and reduced transepidermal water loss compared to a saline dressing in 60 subjects undergoing facial laser treatment. ([Journal of Cosmetic Dermatology, 2025](https://pubmed.ncbi.nlm.nih.gov/40613435/))
- Topical gel containing chitosan, 0.2% chlorhexidine, allantoin and dexpanthenol did not improve postoperative comfort regarding swelling and pain, but improved the wound's aesthetic appearance following impacted lower third molar extraction compared to no gel. ([Medicina Oral, Patologia Oral Y Cirugia Bucal, 2016](https://pubmed.ncbi.nlm.nih.gov/27475700/))
- Topical application of 0.1% hyaluronic acid formulations of different molecular weights led to significant improvements in skin hydration and elasticity, with low-molecular-weight formulations also significantly reducing wrinkle depth in seventy-six female subjects compared to a vehicle control. ([Journal of Drugs in Dermatology, 2011](https://pubmed.ncbi.nlm.nih.gov/22052267/))
- Topical application of hyaluronic acid in conjunction with free gingival graft significantly reduced donor site postoperative pain until day 7 compared to normal saline, with no significant differences in graft dimensions or patient satisfaction. ([Clinical Oral Investigations, 2022](https://pubmed.ncbi.nlm.nih.gov/34623507/))
- Treatment with a hyaluronic acid-containing mouth rinse or topical gel led to significant lesion reduction, pain relief, and normalization of lesion color in adult patients with minor recurrent aphthous stomatitis, with the gel formulation showing an earlier healing onset at 3 days. ([BMC Oral Health, 2019](https://pubmed.ncbi.nlm.nih.gov/31311529/))
- The emollient V0034CR significantly reduced TEWL compared to vehicle and vehicle plus glycerol, and significantly increased corneometry scores compared to vehicle and vehicle plus petrolatum in healthy volunteers with dry skin, demonstrating combined barrier function improvement from petrolatum and hydration improvement from glycerol. ([Journal of Cosmetic Dermatology, 2020](https://pubmed.ncbi.nlm.nih.gov/31532576/))
- Ten days of treatment with a cream containing 20% glycerin significantly increased skin hydration measured by corneometer values in 17 healthy volunteers compared to a placebo cream, but showed no influence on transepidermal water loss or skin sensitivity to an irritating surfactant. ([International Journal of Cosmetic Science, 2001](https://pubmed.ncbi.nlm.nih.gov/18498456/))
- Niacinamide/glycerin body moisturizers provided better rapid and prolonged improvement of cosmetic xerosis through functional improvement of stratum corneum barrier function compared to no treatment and conventional moisturizers in female subjects. ([Journal of Drugs in Dermatology, 2012](https://pubmed.ncbi.nlm.nih.gov/22206073/))
- Topical application of an emulsion containing a complete mixture of ceramides III, IIIB, VI, phytosphingosine, cholesterol, and linoleic acid significantly accelerated barrier recovery after SLS damage and improved skin hydration after acetone treatment in human volunteers compared to an emulsion containing only two types of ceramides. ([Journal of the European Academy of Dermatology and Venereology, 2002](https://pubmed.ncbi.nlm.nih.gov/12482041/))
- Phytosphingosine demonstrates anti-microbial and anti-inflammatory activity with excellent clinical results in acne vulgaris. ([International Journal of Cosmetic Science, 2007](https://pubmed.ncbi.nlm.nih.gov/18489348/))
- Phytosphingosine increased filaggrin metabolism and skin hydration in human skin by stimulating filaggrin biosynthesis and degradation leading to natural moisturizing factor formation. ([Archives of Dermatological Research, 2017](https://pubmed.ncbi.nlm.nih.gov/28936777/))
- Botulinum toxin-A encapsulated in phosphatidylcholine/cholesterol nanoliposomes delivered transdermally achieved a diffusion depth of 380 μm and showed a nonsignificant advantage in relieving post-acne scarring compared to hyaluronic acid hydrogel treatment in 12 facial patients. ([Journal of Materials Science. Materials in Medicine, 2024](https://pubmed.ncbi.nlm.nih.gov/39073502/))
- Topical application of cholesterol sulfate increases stratum corneum thickness and inhibits protease-induced cell dissociation by competitively inhibiting serine proteases in mice and human stratum corneum. ([The Journal of Investigative Dermatology, 1998](https://pubmed.ncbi.nlm.nih.gov/9699715/))
- Topical lovastatin treatment impairs the recovery of cutaneous permeability barrier function and stratum corneum cholesterol levels after acetone disruption in mice, an effect normalized by simultaneous treatment with mevalonate or cholesterol. ([The Journal of Clinical Investigation, 1990](https://pubmed.ncbi.nlm.nih.gov/2243142/))

## What reviewers say

Users with dry, sensitive, and combination skin praise this serum for its ability to repair the moisture barrier and calm redness without causing irritation. The lightweight, fragrance-free formula is frequently noted for improving skin texture and providing long-lasting hydration, though some users with oily skin find it leaves a slight tackiness.

- Liked: Lightweight & non-greasy (mostly mentioned)
- Liked: Effective hydration (often mentioned)
- Liked: Soothing & gentle (often mentioned)
- Liked: Improves skin texture (sometimes noted)
- Disliked: Price vs. size (sometimes noted)
- Disliked: Insufficient for very dry (rarely noted)
- Disliked: Packaging issues (rarely noted)
- Disliked: Slight tackiness (rarely noted)

## How to apply

- Use this soothing AM and PM routine every day to keep your normal skin calm. Always remember to apply SPF in the morning after your moisturizer.
- Apply your moisturizer after your toner in the morning, and after your serum in the evening. This step locks in hydration and protects your skin.
- Gently press a small amount of the moisturizer evenly across your face. Avoid rubbing to keep your sensitive skin happy and calm.
- You can apply this gentle formula on dry or slightly damp skin for the best comfort. It works wonderfully on clean skin to soothe redness and irritation.
- Do a patch test before your very first use to check your skin's reaction. Avoid getting the product directly into your eyes .
- Video: https://storage.pora.ai/2f72f5d69f07beeafc30237f829efbff.mp4

## Questions and answers

### How well does Cetaphil Ceramide Serum work for sensitive skin?

This serum works reasonably well for sensitive skin, offering moderate hydration and soothing effects that help calm redness and irritation. To fit this skin type best, a moisturizing treatment needs a richer blend of intense hydrators, calming plant extracts, and peptides that support moisture retention and radiance without any risk of irritation.
Sources: [American Journal of Clinical Dermatology, 2002](https://pubmed.ncbi.nlm.nih.gov/12113650/), [Clinical, Cosmetic and Investigational Dermatology, 2017](https://pubmed.ncbi.nlm.nih.gov/28860834/)

### Which ingredients make this serum a good fit for sensitive skin?

This serum helps your sensitive skin with glycerin, hyaluronic acid, and panthenol, which provide supportive hydration and soothing effects for redness and irritation. It also includes ceramides, cholesterol, and allantoin to calm the skin and enhance your skin barrier function. To achieve a better fit for sensitive skin, this type of product needs rich hydrating ingredients along with beneficial plant extracts or peptides that improve moisture retention and radiance without any risk of irritation.
Sources: [American Journal of Clinical Dermatology, 2002](https://pubmed.ncbi.nlm.nih.gov/12113650/), [Clinical, Cosmetic and Investigational Dermatology, 2017](https://pubmed.ncbi.nlm.nih.gov/28860834/)

### What do Ceramides do for sensitive skin?

Ceramides help calm and strengthen sensitive skin by improving moisture barriers and reducing discomfort. Topical use is well tolerated and may significantly increase skin hydration while easing stinging or sensitive sensations.
Sources: [Archives of Dermatological Research, 2018](https://pubmed.ncbi.nlm.nih.gov/29728858/), [Skin Pharmacology and Physiology, 2026](https://pubmed.ncbi.nlm.nih.gov/41758783/)

### What does Hyaluronic Acid do for sensitive skin?

Hyaluronic acid helps calm and hydrate sensitive skin while supporting the skin barrier to keep it soft and comfortable. Clinical studies show it improves surface moisture and reduces dryness, roughness, and redness without irritation.
Sources: [Journal of Drugs in Dermatology, 2025](https://pubmed.ncbi.nlm.nih.gov/41037531/), [Journal of Cosmetic Dermatology, 2018](https://pubmed.ncbi.nlm.nih.gov/29356277/)

### Where does this serum go in a skincare routine for sensitive skin?

This treatment goes in the evening routine for your sensitive skin, after your toner and before your moisturizer. Putting it in the evening keeps things simple and helps avoid extra safety concerns around sun exposure.

### Can I use this serum with retinol, and in what order?

You can use this serum with retinol by applying it before your retinol to help calm your skin and keep it soft. A product of this type for sensitive skin needs soothing ingredients like allantoin and panthenol along with gentle barrier-supporting ceramides to prevent irritation.
Sources: [Cutis, 2006](https://pubmed.ncbi.nlm.nih.gov/17121065/), [American Journal of Clinical Dermatology, 2002](https://pubmed.ncbi.nlm.nih.gov/12113650/)

### How often should I use this serum?

This serum works well in your evening routine, applied once daily for simplicity and extra safety around sun exposure. Daily application helps improve skin moisture and keeps sensitive skin calm and comfortable.
Sources: [Health Science Reports, 2021](https://pubmed.ncbi.nlm.nih.gov/34141902/), [Dermatology, 2003](https://pubmed.ncbi.nlm.nih.gov/14571069/)

### Can this serum clog pores, cause breakouts or purging for sensitive skin?

This serum is unlikely to clog pores or cause breakouts on sensitive skin, as it lacks heavy, pore-clogging oils and contains calming ingredients like allantoin and panthenol. It also does not contain active ingredients that speed up skin shedding, so it will not cause purging.
Sources: [American Journal of Clinical Dermatology, 2002](https://pubmed.ncbi.nlm.nih.gov/12113650/), [The Journal of Dermatological Treatment, 2017](https://pubmed.ncbi.nlm.nih.gov/27425824/)

### Can I use this serum around the eyes or on my body?

You can use this serum on the thin skin around the eyes and on the body, as its gentle ingredients are generally safe for sensitive areas. However, because it is an average fit for your skin, a product of this type needs extra soothing plant extracts and richer barrier-repairing oils to give you better results.
Sources: [Surgical and Radiologic Anatomy, 2002](https://pubmed.ncbi.nlm.nih.gov/12375070/), [American Journal of Clinical Dermatology, 2002](https://pubmed.ncbi.nlm.nih.gov/12113650/)

### Is this serum fragrance-free and alcohol-free?

Yes, it has no fragrance and no drying alcohol. Cetearyl alcohol is a fatty alcohol, which soften the skin.

## Alternatives for sensitive skin

- [innisfree Green Tea Seed Hyaluronic Acid Hydrating Serum](https://lovi.care/skincare/ae/p/innisfree/green-tea-seed-hyaluronic-acid-hydrating-serum/for/sensitive-skin) — High fit — AED 92.81 at Amazon
- [Isntree Green Tea Fresh Serum](https://lovi.care/skincare/ae/p/isntree/green-tea-fresh-serum/for/sensitive-skin) — High fit — AED 75.41 at Amazon
- [Revision Skincare Hydrating Serum](https://lovi.care/skincare/ae/p/revision-skincare/hydrating-serum/for/sensitive-skin) — High fit — AED 333.85 at Amazon

## Pairs well with

- Cleanser: [Fresh Soy Face Cleanser](https://lovi.care/skincare/ae/p/fresh/soy-face-cleanser/for/sensitive-skin) — Superior fit — AED 84.53 at Amazon
- Soothing Toner: [Clarins Toning Lotion with Camomile](https://lovi.care/skincare/ae/p/clarins/soothing-toning-lotion/for/sensitive-skin) — Superior fit — AED 81.41 at Amazon
- Moisturizer with Sun Protection: [Bioderma Bioderma Photoderm Mineral SPF 50+](https://lovi.care/skincare/ae/p/bioderma/photoderm-mineral-fluide-spf50/for/sensitive-skin) — Superior fit — AED 65.10 at Amazon

## Where to buy

No store in United Arab Emirates has a checked price for this product, so the page shows none.

## Ingredients

Water, Glycerin, Caprylic Capric Triglyceride, Cetearyl Alcohol, Ceteareth-20, Ceramide Np, Ceramide Ap, Ceramide Eop, Phytosphingosine, Cholesterol, Hyaluronic Acid, Tocopheryl Acetate, Panthenol, Allantoin, Xanthan Gum, Carbomer, Disodium Edta, Phenoxyethanol, Ethylhexylglycerin
## About the Lovi Fit

Lovi: Unbiased, science-based skincare AI trained on real user outcomes.

Lovi calculates every fit score from the full ingredient list with brand-independent rules its dermatologists and cosmetic chemists build and review, and personalizes every pick with AI trained on the real results of millions of users. Lovi trains its fit score models on a proprietary dataset built from more than 10,000 expert-labeled products and more than 100,000 simulated examples, following an internally consistent methodology presented at Cosmoprof, AMWC, and Skin of Color Update. Levels from best to worst: Superior, High, Average, Low, Caution, Warning.

Behind this fit score: Nadia Kapleva, MS (Co-founder, Medical Director); Alexey Shagraev, PhD (Co-founder, CEO and CTO); Dr. Sofía Perea Pérez, MD, MSc (Medical Board); Aishani Shah, MD (Medical Board); Asya Zubkova, MS (Medical Board); Hanna Kurets, MD (Medical Board, Medical Advisor); Elina Nazarenko, MD (Medical Board); Victoria Derkova, MS (Medical Board).

Page built Nov 8, 2026.

More from Lovi: https://lovi.care/skincare/llms.txt

## This page in other countries

- United States: https://lovi.care/skincare/p/cetaphil/ceramide-serum/for/sensitive-skin
- United Kingdom: https://lovi.care/skincare/uk/p/cetaphil/ceramide-serum/for/sensitive-skin
- Ireland: https://lovi.care/skincare/ie/p/cetaphil/ceramide-serum/for/sensitive-skin
- Germany: https://lovi.care/skincare/de/p/cetaphil/ceramide-serum/for/sensitive-skin
- France: https://lovi.care/skincare/fr/p/cetaphil/ceramide-serum/for/sensitive-skin
- Italy: https://lovi.care/skincare/it/p/cetaphil/ceramide-serum/for/sensitive-skin
- Netherlands: https://lovi.care/skincare/nl/p/cetaphil/ceramide-serum/for/sensitive-skin
- Spain: https://lovi.care/skincare/es/p/cetaphil/ceramide-serum/for/sensitive-skin
- Canada: https://lovi.care/skincare/ca/p/cetaphil/ceramide-serum/for/sensitive-skin
- Australia: https://lovi.care/skincare/au/p/cetaphil/ceramide-serum/for/sensitive-skin
- Singapore: https://lovi.care/skincare/sg/p/cetaphil/ceramide-serum/for/sensitive-skin
- Saudi Arabia: https://lovi.care/skincare/sa/p/cetaphil/ceramide-serum/for/sensitive-skin
- United Arab Emirates: https://lovi.care/skincare/ae/p/cetaphil/ceramide-serum/for/sensitive-skin (this page)