# celimax The Real Cica Calming Ampoule for mature skin

**Lovi Fit: High fit for mature skin.**
Normal Skin Fit: High · Effectiveness: High · Safety: Excellent.

Page: https://lovi.care/skincare/ae/p/celimax/the-real-cica-calming-ampoule/for/mature-skin

The Lovi Fit is the same in every country; only the stores and prices differ, and the ones here are for the United Arab Emirates.

Brand: [celimax](https://lovi.care/skincare/ae/brands/celimax)
Category: [Serums and treatments](https://lovi.care/skincare/ae/best/serums)

This fit is calculated for the concerns frequently associated with mature skin: fine lines, wrinkles, and loss of firmness. For scores based on a full skin profile (12D face scan, goals, preferences), use the Lovi app.

One of the best serums for mature skin.

## Why this fit

- Highly suitable for your normal skin, this product's Centella Asiatica Extract and Madecassoside effectively calm irritation and support skin repair, addressing your concerns about wrinkles and fine lines.
- The inclusion of Panthenol and Beta-Glucan further enhances barrier function and hydration, complementing the primary soothing ingredients.
- The formulation is safe for your skin, with no reported risks of irritation due to its gentle composition and absence of harsh chemicals.

## Fit by skin type

- [Oily skin](https://lovi.care/skincare/ae/p/celimax/the-real-cica-calming-ampoule/for/oily-skin): High
- [Dry skin](https://lovi.care/skincare/ae/p/celimax/the-real-cica-calming-ampoule/for/dry-skin): High
- [Combination skin](https://lovi.care/skincare/ae/p/celimax/the-real-cica-calming-ampoule/for/combination-skin): High
- [Sensitive skin](https://lovi.care/skincare/ae/p/celimax/the-real-cica-calming-ampoule/for/sensitive-skin): Superior
- [Acne-prone skin](https://lovi.care/skincare/ae/p/celimax/the-real-cica-calming-ampoule/for/acne-prone-skin): High
- [Skin with dark spots](https://lovi.care/skincare/ae/p/celimax/the-real-cica-calming-ampoule/for/dark-spots): High
- [Mature skin](https://lovi.care/skincare/ae/p/celimax/the-real-cica-calming-ampoule/for/mature-skin): High (this page)
- [Dry sensitive skin](https://lovi.care/skincare/ae/p/celimax/the-real-cica-calming-ampoule/for/dry-sensitive-skin): High
- [Oily acne-prone skin](https://lovi.care/skincare/ae/p/celimax/the-real-cica-calming-ampoule/for/oily-acne-prone-skin): Superior

## Key ingredients

Centella Asiatica Extract, Madecassoside, Sodium Hyaluronate, Allantoin, Beta-Glucan

## What the research says

- Cosmetic formulations containing 5% Centella asiatica extract showed the best efficacy in improving skin moisture and decreasing transepidermal water loss, while also exhibiting antiinflammatory properties in 25 volunteers compared to baseline measurements. ([Indian Journal of Pharmaceutical Sciences, 2016](https://pubmed.ncbi.nlm.nih.gov/27168678/))
- Topical dexpanthenol acts as a moisturizer, improves stratum corneum hydration, accelerates wound healing and epidermal regeneration, reduces erythema, and improves symptoms of skin irritation compared to vehicle or no pretreatment. ([American Journal of Clinical Dermatology, 2002](https://pubmed.ncbi.nlm.nih.gov/12113650/))
- A new topical panthenol-containing emollient significantly improved transepidermal water loss reduction, stratum corneum hydration, and intercellular lipid lamellae length compared with control in healthy subjects without negatively impacting bacterial viability. ([The Journal of Dermatological Treatment, 2017](https://pubmed.ncbi.nlm.nih.gov/27425824/))
- Skin care regimens containing beta-glucan improved hemoglobin index, skin hydration, and transepidermal water loss compared to vehicle control in 20 patients undergoing fractional laser therapy. ([Journal of Cosmetic Dermatology, 2021](https://pubmed.ncbi.nlm.nih.gov/33128496/))
- Topical application of 0.05% w/w ECa 233 gel reduced erythema index by 0.03 U and improved early crusting and general wound appearance compared to placebo in thirty individuals undergoing facial laser resurfacing. ([Journal of Alternative and Complementary Medicine, 2020](https://pubmed.ncbi.nlm.nih.gov/32310680/))
- A single application of a moisturizing fluid containing hyaluronic acid 1%, glycerin 5%, and Centella asiatica stem cells extract significantly increased skin hydration by 29% and reduced transepidermal water loss at 24 hours compared to baseline and an untreated control site in twenty healthy women. ([Clinical, Cosmetic and Investigational Dermatology, 2017](https://pubmed.ncbi.nlm.nih.gov/28860834/))
- Moisturizer containing 5% panthenol, madecassoside, and copper-zinc-manganese decreased adverse reactions and downtime after ablative fractional carbon dioxide laser resurfacing with comparable efficacy to 0.02% triamcinolone acetonide cream in 20 subjects. ([Journal of Cosmetic Dermatology, 2019](https://pubmed.ncbi.nlm.nih.gov/30945430/))
- Topical application of 0.1% hyaluronic acid formulations of different molecular weights led to significant improvements in skin hydration and elasticity, with low-molecular-weight formulations also significantly reducing wrinkle depth in seventy-six female subjects compared to a vehicle control. ([Journal of Drugs in Dermatology, 2011](https://pubmed.ncbi.nlm.nih.gov/22052267/))
- Topical application of hyaluronic acid in conjunction with free gingival graft significantly reduced donor site postoperative pain until day 7 compared to normal saline, with no significant differences in graft dimensions or patient satisfaction. ([Clinical Oral Investigations, 2022](https://pubmed.ncbi.nlm.nih.gov/34623507/))
- Treatment with a hyaluronic acid-containing mouth rinse or topical gel led to significant lesion reduction, pain relief, and normalization of lesion color in adult patients with minor recurrent aphthous stomatitis, with the gel formulation showing an earlier healing onset at 3 days. ([BMC Oral Health, 2019](https://pubmed.ncbi.nlm.nih.gov/31311529/))
- Topical gel containing chitosan, 0.2% chlorhexidine, allantoin and dexpanthenol did not improve postoperative comfort regarding swelling and pain, but improved the wound's aesthetic appearance following impacted lower third molar extraction compared to no gel. ([Medicina Oral, Patologia Oral Y Cirugia Bucal, 2016](https://pubmed.ncbi.nlm.nih.gov/27475700/))
- A topical gel containing chitosan, chlorhexidine, allantoin, and dexpanthenol significantly reduced postoperative pain, trismus, swelling, and analgesic consumption, while improving wound healing after third molar surgery compared to a placebo. ([Medicina Oral, Patologia Oral Y Cirugia Bucal, 2020](https://pubmed.ncbi.nlm.nih.gov/32683390/))
- An overnight patch containing Allium cepa extract and allantoin safely promotes scar healing after dermatologic surgery, resulting in significantly greater reductions in observer- and patient-assessed POSAS scores compared to no treatment. ([Aesthetic Plastic Surgery, 2018](https://pubmed.ncbi.nlm.nih.gov/29948103/))
- Treatment with topical formulations containing beta-glucan combined with nanofractional radiofrequency plus magnetic nanofractional radiofrequency showed the best efficacy and was tolerable and effective in Chinese women with abdominal stretch marks compared to control groups. ([Dermatology and Therapy, 2023](https://pubmed.ncbi.nlm.nih.gov/37171578/))
- Topical beta-glucan mildly improved striae gravidarum, 1565-nm non-ablative fractional laser showed better results than topical beta-glucan, and the combined strategy further improved striae gravidarum atrophy compared to single treatment. ([The Journal of Dermatology, 2022](https://pubmed.ncbi.nlm.nih.gov/35570397/))
- Topical application of oat beta-glucan ameliorates epidermal hyperplasia and accelerates epidermal barrier recovery by promoting keratinocyte differentiation through dectin-1-mediated ERK and p38 signaling pathways that upregulate CaSR expression. ([International Journal of Biological Macromolecules, 2021](https://pubmed.ncbi.nlm.nih.gov/34237364/))

## What reviewers say

This ampoule is highly regarded for its ability to calm sensitive and acne-prone skin, effectively reducing redness and irritation. Its lightweight, non-sticky texture is particularly favored by those with oily and combination skin, providing fresh hydration. However, individuals with dry skin may find it necessary to layer with a richer moisturizer for adequate hydration, especially in colder months.

- Liked: Soothing and calming (mostly mentioned)
- Liked: Lightweight texture (often mentioned)
- Liked: Sensitive skin friendly (often mentioned)
- Liked: Acne and blemish care (sometimes noted)
- Disliked: Dry skin hydration (sometimes noted)
- Disliked: Mild stickiness (rarely noted)
- Disliked: Packaging issues (rarely noted)
- Disliked: Small size (rarely noted)

## How to apply

- Use this serum in your PM routine. Start by applying it 3 times a week, and work up to daily use if your skin likes it.
- Apply this serum after your toner and before your moisturizer.
- Gently press 2-3 drops of the serum into your skin and let it absorb for a minute.
- You can apply the serum on dry skin for the best results against fine lines.
- Always do a patch test before your first use and avoid the sensitive eye area.
- Video: https://storage.pora.ai/c879dda8655a61c19d3d8c9ebad6b06d.mp4

## Questions and answers

### What makes celimax The Real Cica Calming Ampoule a great fit for mature skin?

This product is a great fit because its Centella Asiatica Extract and Madecassoside calm irritation and support skin repair to help address wrinkles and fine lines. Panthenol and Beta-Glucan work together to boost hydration and strengthen your skin barrier so it stays soft and smooth.
Sources: [American Journal of Clinical Dermatology, 2002](https://pubmed.ncbi.nlm.nih.gov/12113650/), [The Journal of Dermatological Treatment, 2017](https://pubmed.ncbi.nlm.nih.gov/27425824/)

### Which ingredients make this serum a good fit for mature skin?

Centella Asiatica Extract and Madecassoside make this serum a great fit for mature skin by calming irritation and supporting skin repair to help address wrinkles and fine lines. Additionally, Panthenol and Beta-Glucan help enhance hydration and strengthen the skin barrier.
Sources: [American Journal of Clinical Dermatology, 2002](https://pubmed.ncbi.nlm.nih.gov/12113650/), [The Journal of Dermatological Treatment, 2017](https://pubmed.ncbi.nlm.nih.gov/27425824/)

### What does Centella Asiatica Extract do for mature skin?

Centella Asiatica Extract helps mature skin by improving moisture, reducing moisture loss, and supporting collagen production to keep skin firm and smooth. It also provides antioxidant and calming benefits that help protect against everyday stress and visible signs of aging.
Sources: [Scientific Reports, 2021](https://pubmed.ncbi.nlm.nih.gov/34188145/), [International Journal of Molecular Sciences, 2025](https://pubmed.ncbi.nlm.nih.gov/41516082/)

### What does Madecassoside do for mature skin?

Madecassoside helps mature skin by supporting collagen production to keep skin firm and smooth while calming irritation. It is unlikely to cause irritation and may protect against signs of aging and sun damage.
Sources: [Journal of Medicinal Food, 2023](https://pubmed.ncbi.nlm.nih.gov/37976111/), [Annales Pharmaceutiques Francaises, 1995](https://pubmed.ncbi.nlm.nih.gov/7741425/)

### Where does this serum go in a skincare routine for mature skin?

This treatment goes in the evening routine after cleansing and before moisturizing. Putting treatments in the evening keeps the routine simple and adds safety around sun exposure.

### Can I use this serum with retinol, and in what order?

Yes, you can use this serum with retinol by applying the serum first to calm your skin and boost hydration before putting on your retinol. This gentle routine helps keep your skin comfortable while supporting repair and reducing any dryness from the retinol.
Sources: [American Journal of Clinical Dermatology, 2002](https://pubmed.ncbi.nlm.nih.gov/12113650/), [The Journal of Dermatological Treatment, 2017](https://pubmed.ncbi.nlm.nih.gov/27425824/)

### How often should I use this serum?

This serum is a great fit for your mature skin and is used in the evening routine. Its soothing ingredients help calm irritation while supporting skin repair and hydration, with a very low likelihood of causing irritation.
Sources: [American Journal of Clinical Dermatology, 2002](https://pubmed.ncbi.nlm.nih.gov/12113650/), [The Journal of Dermatological Treatment, 2017](https://pubmed.ncbi.nlm.nih.gov/27425824/)

### Can this serum clog pores, cause breakouts or purging for mature skin?

This product is unlikely to clog pores or cause breakouts for mature skin. Its gentle ingredients like Centella Asiatica and panthenol calm and hydrate without heavy oils.
Sources: [American Journal of Clinical Dermatology, 2002](https://pubmed.ncbi.nlm.nih.gov/12113650/), [The Journal of Dermatological Treatment, 2017](https://pubmed.ncbi.nlm.nih.gov/27425824/)

### Is this serum fragrance-free and alcohol-free?

Yes, it has no fragrance and no drying alcohol.

## Alternatives for mature skin

- [Clarins Double Serum](https://lovi.care/skincare/ae/p/clarins/double-serum/for/mature-skin) — High fit — AED 440.00 at Amazon
- [Dewytree Miracle Clear Serum](https://lovi.care/skincare/ae/p/dewytree/miracle-clear-serum/for/mature-skin) — High fit — AED 74.78 at Amazon
- [SKIN1004 Madagascar Centella Asiatica Ampoule](https://lovi.care/skincare/ae/p/skin1004/madagascar-centella-asiatica-ampoule/for/mature-skin) — Average fit — AED 41.20 at Amazon

## Pairs well with

- Cleanser: [Fresh Soy Face Cleanser](https://lovi.care/skincare/ae/p/fresh/soy-face-cleanser/for/mature-skin) — Superior fit — AED 84.53 at Amazon
- Hydrating Toner: [COSRX Propolis Synergy Toner](https://lovi.care/skincare/ae/p/cosrx/full-fit-propolis-synergy-toner/for/mature-skin) — Superior fit — AED 65.43 at Amazon
- Moisturizer: [Elizabeth Arden Ceramide Lift and Firm Night Cream](https://lovi.care/skincare/ae/p/elizabeth-arden/advanced-ceramide-lift-and-firm-night-cream/for/mature-skin) — Superior fit — AED 493.00 at Amazon

## Where to buy

- Amazon.ae: AED 48.45 (https://www.amazon.ae/dp/B0CGJD3GV1?tag=lovi00-21&linkCode=osi&th=1&psc=1)
Prices checked 6 Nov 2026.

## Ingredients

Centella Asiatica Extract, Water, Dipropylene Glycol, 1,2-Hexanediol, Butylene Glycol, Hydroxyethyl Urea, Glycerin, Polyglyceryl-10 Myristate, Carbomer, Tromethamine, Hydroxyacetophenone, Caprylyl Glycol, Ethylhexylglycerin, Melia Azadirachta Leaf Extract, Melia Azadirachta Flower Extract, Allantoin, Disodium Edta, Madecassoside, Portulaca Oleracea Extract, Glyceryl Acrylate Acrylic Acid Copolymer, Trehalose, Panthenol, Pvm Ma Copolymer, Beta-Glucan, Biosaccharide Gum-1, Dipotassium Glycyrrhizate, Sodium Hyaluronate, Hydrolyzed Hyaluronic Acid, Sodium Acetylated Hyaluronate, Asiaticoside, Asiatic Acid, Madecassic Acid
## About the Lovi Fit

Lovi: Unbiased, science-based skincare AI trained on real user outcomes.

Lovi calculates every fit score from the full ingredient list with brand-independent rules its dermatologists and cosmetic chemists build and review, and personalizes every pick with AI trained on the real results of millions of users. Lovi trains its fit score models on a proprietary dataset built from more than 10,000 expert-labeled products and more than 100,000 simulated examples, following an internally consistent methodology presented at Cosmoprof, AMWC, and Skin of Color Update. Levels from best to worst: Superior, High, Average, Low, Caution, Warning.

Behind this fit score: Nadia Kapleva, MS (Co-founder, Medical Director); Alexey Shagraev, PhD (Co-founder, CEO and CTO); Dr. Sofía Perea Pérez, MD, MSc (Medical Board); Aishani Shah, MD (Medical Board); Asya Zubkova, MS (Medical Board); Hanna Kurets, MD (Medical Board, Medical Advisor); Elina Nazarenko, MD (Medical Board); Victoria Derkova, MS (Medical Board).

Page built Nov 8, 2026.

More from Lovi: https://lovi.care/skincare/llms.txt

## This page in other countries

- United States: https://lovi.care/skincare/p/celimax/the-real-cica-calming-ampoule/for/mature-skin
- United Kingdom: https://lovi.care/skincare/uk/p/celimax/the-real-cica-calming-ampoule/for/mature-skin
- Ireland: https://lovi.care/skincare/ie/p/celimax/the-real-cica-calming-ampoule/for/mature-skin
- Germany: https://lovi.care/skincare/de/p/celimax/the-real-cica-calming-ampoule/for/mature-skin
- France: https://lovi.care/skincare/fr/p/celimax/the-real-cica-calming-ampoule/for/mature-skin
- Italy: https://lovi.care/skincare/it/p/celimax/the-real-cica-calming-ampoule/for/mature-skin
- Netherlands: https://lovi.care/skincare/nl/p/celimax/the-real-cica-calming-ampoule/for/mature-skin
- Spain: https://lovi.care/skincare/es/p/celimax/the-real-cica-calming-ampoule/for/mature-skin
- Canada: https://lovi.care/skincare/ca/p/celimax/the-real-cica-calming-ampoule/for/mature-skin
- Australia: https://lovi.care/skincare/au/p/celimax/the-real-cica-calming-ampoule/for/mature-skin
- Singapore: https://lovi.care/skincare/sg/p/celimax/the-real-cica-calming-ampoule/for/mature-skin
- Saudi Arabia: https://lovi.care/skincare/sa/p/celimax/the-real-cica-calming-ampoule/for/mature-skin
- United Arab Emirates: https://lovi.care/skincare/ae/p/celimax/the-real-cica-calming-ampoule/for/mature-skin (this page)