Canmake Mermaid Skin Gel UV for acne-prone skin

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Questions and answers

What the research says

• Rice-derived glucosylceramides and ceramides with specific fatty acid chain lengths significantly reduced transepidermal water loss and exhibited distinct hydration mechanisms in a reconstructed human epidermal keratinization model.

  International Journal of Molecular Sciences, 2022

• Microfine titanium dioxide does not penetrate human skin when formulated in an oil-in-water emulsion with the pigment dispersed in the aqueous phase, compared to oily dispersions and liposomal encapsulation which allow deeper skin penetration.

  International Journal of Cosmetic Science, 2000

• Biomimetic hyaluronic acid-stabilized zinc oxide nanoparticles selectively inhibited C. acnes, outperformed erythromycin in preclinical acne models, and safely reduced acne lesions and redness in a clinical trial.

  Journal of Controlled Release, 2025

• Topical 0.5% hyaluronic-ZnO nanogel applied twice daily reduced inflammatory-lesion counts by 58% at week four in human subjects compared to baseline without causing erythema.

  Biomedicines, 2025

• Topical treatment with 1% Ag-ZnO/AgO nanocomposite accelerated wound closure, demonstrated anti-inflammatory and antioxidant effects, increased collagen deposition, and raised metalloproteinases 2 and 9 activity compared to untreated wounds in mice.

  International Journal of Pharmaceutics, 2022

• Nels cream achieved a similar reduction in inflammatory and noninflammatory lesion counts compared to 5% benzoyl peroxide in acne vulgaris patients, but caused significantly fewer side-effects such as peeling and dryness.

  Clinical and Experimental Dermatology, 2000

• Topically applied coated and uncoated zinc oxide nanoparticles under flexing and massage are retained in the stratum corneum with no significant penetration into the viable epidermis and no cellular toxicity in human skin.

  Nanomedicine, 2016

• Oral and dermal administration of Uvinul A plus resulted in three major urinary metabolites accounting for 52% of the oral dose, with a very low estimated daily systemic exposure of 8.1-9.3 μg/d in volunteers not intentionally exposed.

  International Journal of Hygiene and Environmental Health, 2020

• Replacing 20% of the chemical UV filter octyl methoxycinnamate with urucum oil in solid lipid nanoparticles maintained the skin protection factor without inducing toxic responses or significant skin penetration in human volunteers.

  Skin Pharmacology and Physiology, 2018

• Liposomal encapsulation of octyl methoxycinnamate increases its safety, skin affinity, and in vivo solar photoprotection factor while slowing its release and enhancing retention in the stratum corneum compared to a conventional formulation.

  International Journal of Nanomedicine, 2013

• Encapsulation of ethylhexyl methoxycinnamate and butyl methoxydibenzoylmethane in lipid microparticles significantly reduced their in vivo human skin penetration compared to nonencapsulated filters.

  Skin Pharmacology and Physiology, 2011

• Topical application of 0.1% hyaluronic acid formulations of different molecular weights led to significant improvements in skin hydration and elasticity, with low-molecular-weight formulations also significantly reducing wrinkle depth in seventy-six female subjects compared to a vehicle control.

  Journal of Drugs in Dermatology, 2011

• Topical application of hyaluronic acid in conjunction with free gingival graft significantly reduced donor site postoperative pain until day 7 compared to normal saline, with no significant differences in graft dimensions or patient satisfaction.

  Clinical Oral Investigations, 2022

• Treatment with a hyaluronic acid-containing mouth rinse or topical gel led to significant lesion reduction, pain relief, and normalization of lesion color in adult patients with minor recurrent aphthous stomatitis, with the gel formulation showing an earlier healing onset at 3 days.

  BMC Oral Health, 2019

Ingredients

Water, Ethylhexyl Methoxycinnamate, Butylene Glycol, Diethylamino Hydroxybenzoyl Hexyl Benzoate, Zinc Oxide, Methylheptyl Laurate, Titanium Dioxide, Dimethicone, Bis-Ethylhexyloxyphenol Methoxyphenyl Triazine, Polymethylsilsesquioxane, Cyclopentasiloxane, Hydroxyethyl Acrylate Sodium Acryloyldimethyl Taurate Copolymer, Diisostearyl Malate, Aluminum Hydroxide, Peg-60 Hydrogenated Castor Oil, Stearic Acid, Phenoxyethanol, Polyglyceryl-3 Polydimethylsiloxyethyl Dimethicone, Polyhydroxystearic Acid, Jojoba Esters, Xanthan Gum, Arginine, Sodium Hyaluronate, Alpha-Glucan, Phytic Acid, Saxifraga Sarmentosa Extract, Glucosyl Ceramide, Prunus Yedoensis Leaf Extract, Coix Lacryma-Jobi Ma-Yuen Seed Extract, Morus Alba Root Extract, Oenothera Biennis Seed Extract, Silver Oxide, Spiraea Ulmaria Flower Extract, Vaccinium Myrtillus Leaf Extract, Cynara Scolymus Leaf Extract

Behind this fit score

Lovi calculates every fit score from the full ingredient list with brand-independent rules our dermatologists and cosmetic chemists build and review, and personalizes every pick with AI trained on the real results of millions of users. Lovi trains its fit score models on a proprietary dataset built from more than 10,000 expert-labeled products and more than 100,000 simulated examples, following an internally consistent methodology presented at Cosmoprof, AMWC, and Skin of Color Update.