Biossance Squalane + Probiotic Gel Moisturizer for combination skin
Squalane
Probiotics
Glycerin
Lactococcus Lysate Ferment
Zingiber Officinale Root Extract
High
- HighCombination Skin Fit
- HighEffectiveness
- HighSafety
A great choice for combination skin; a few moisturizers fit it even better.
This fit is calculated for the concerns frequently associated with combination skin: an oily T-zone, enlarged pores, and dry cheeks. For scores and recommendations based on your full skin profile, including your 12D face scan results and any goals or preferences you have, please use the Lovi app.
Page built Nov 8, 2026How the Fit score works
Lovi Assistant explains
- Offers excellent moisturizing for your combination skin, as squalane and glycerin hydrate and enhance barrier resilience without overwhelming oily areas.
- Lactococcus lysate ferment and squalane provide moderate benefits for oily shine by supporting skin barrier function.
- The formulation is safe for your combination skin, with no risks of irritation due to the absence of prohibited or harsh ingredients.
How to apply
- Use this moisturizer in your AM and PM routine every day to control shine. Always pair with SPF in the morning.
- Apply this moisturizer after your cleanser and toner, right before your morning SPF.
- Gently press a small amount of the moisturizer into your skin and avoid harsh rubbing. Let it ⏳absorb for a minute.
- Apply the moisturizer on slightly damp skin to help it lock in moisture better. This keeps your combination skin balanced.
- Avoid the eye area when applying the moisturizer. Do a patch test before your first use.
People Say
★4.5Overall rating based on 2.3k+ reviewsBased on a very large amount of data, this lightweight gel moisturizer is highly recommended for oily, combination, and sensitive skin types, effectively hydrating without pore clogging and visibly reducing redness. However, a significant number of recent reviews indicate dissatisfaction with a formula change, noting a stickier texture and less pleasant scent compared to the original. Dry skin types may find it insufficient for hydration, and some users express concerns about the price point. A small number of users have reported irritation or breakouts.
Highlights
Lightweight & fast absorbing Mostly Mentioned
- “absorbs instantly”
- “feels like water”
- “zero greasy residue”
- “perfect for humid weather”
Balances oily skin Often Mentioned
- “controls my oil”
- “perfect balance”
- “doesn't clog pores”
- “matte but hydrated”
Calms redness & irritation Often Mentioned
- “redness vanished overnight”
- “calms angry skin”
- “instant cooling effect”
Reformulation complaints Often Mentioned
- “new formula is sticky”
- “smells terrible now”
- “too thick”
- “ruined a perfect product”
Excellent makeup base Sometimes Noted
- “makeup glides on”
- “no pilling under sunscreen”
- “acts like a primer”
- “smooth finish”
Not hydrating enough Sometimes Noted
- “skin felt tight”
- “need a second layer”
- “too light for dry skin”
- “not enough moisture”
Price point Sometimes Noted
- “way too expensive”
- “pricey for a basic gel”
- “jar is small”
- “not worth the money”
Irritation and breakouts Rarely Noted
- “burned my face”
- “caused cystic acne”
- “stung upon application”
- “broke me out”
Sources: lovi.care, biossance.com, sephora.com, influenster.com, reddit.com, and more
Questions and answers
What makes Biossance Squalane + Probiotic Gel Moisturizer a great fit for combination skin?
Biossance Squalane + Probiotic Gel Moisturizer is a great fit because squalane and glycerin hydrate dry patches and strengthen your barrier without overwhelming oily areas. Lactococcus lysate ferment and squalane also help manage oily shine by supporting overall skin health, and the gentle formula is very unlikely to cause irritation.
Which ingredients make this moisturizer a good fit for combination skin?
Squalane and glycerin make this moisturizer a great fit for combination skin because they hydrate and strengthen the skin barrier without feeling too heavy on oily areas. Lactococcus lysate ferment and squalane also help manage oily shine by supporting the skin barrier.
What does Squalane do for combination skin?
Squalane helps keep combination skin soft and smooth by locking in moisture without feeling heavy or greasy. It supports the skin barrier and provides lightweight hydration that works well for both dry and oily areas.
Skin Health and Disease, 2024Journal of Nanobiotechnology, 2025
What do Probiotics do for combination skin?
Probiotics help keep combination skin calm and balanced by supporting the skin barrier and reducing irritation across oily and dry areas. They may also improve skin moisture while helping to keep pores clear and skin smooth.
International Journal of Medical Sciences, 2021Experimental Dermatology, 2019
Where does this moisturizer go in a skincare routine for combination skin?
This moisturizer goes as the last step of your morning routine before sunscreen and after your treatment in the evening routine. Applying it then helps lock in hydration and support your skin barrier without feeling too heavy on oily areas.
Can I use this moisturizer with retinol, and in what order?
You can use this moisturizer with retinol by applying the retinol first, letting it absorb, and then following with the moisturizer. This routine helps keep your combination skin calm and hydrated while reducing the dryness and irritation often caused by retinol.
How often should I use this moisturizer?
This moisturizer is a great fit for your combination skin and can be used daily as part of your morning and evening routine. Squalane and glycerin hydrate your skin while helping control oily shine without feeling heavy.
Journal of Cosmetic Dermatology, 2020Health Science Reports, 2021
Can this moisturizer clog pores, cause breakouts or purging for combination skin?
This moisturizer is a great fit for your combination skin and is unlikely to cause irritation or breakouts because it is free of harsh ingredients. Squalane and glycerin hydrate dry patches while keeping oily areas clear, and the safe formula minimizes the risk of clogged pores.
Can I use this moisturizer around the eyes or on my body?
You can use this moisturizing treatment on the thin skin around the eyes and on your body, as its gentle ingredients are well tolerated by delicate areas. Clinical studies show that applying nourishing creams to periorbital and body regions is safe and helps improve skin texture without irritation.
Surgical and Radiologic Anatomy, 2002European Journal of Pharmaceutics and Biopharmaceutics, 2014
Is this moisturizer fragrance-free and alcohol-free?
Yes, it has no fragrance and no drying alcohol.
What the research says
A single application of a moisturizing fluid containing hyaluronic acid 1%, glycerin 5%, and Centella asiatica stem cells extract significantly increased skin hydration by 29% and reduced transepidermal water loss at 24 hours compared to baseline and an untreated control site in twenty healthy women.
Clinical, Cosmetic and Investigational Dermatology, 2017Topical application of Bifida Ferment Lysate strengthens the skin barrier function by upregulating barrier and antimicrobial peptide genes, exhibiting strong antioxidant properties, and decreasing inflammatory cytokine secretion in vitro.
Journal of Cosmetic Dermatology, 2023Squalane at 0.005-0.015% counteracts UVA-induced oxidative stress, inflammation, and collagen metabolism inhibition while stimulating fibroblast migration in human dermal fibroblasts.
Molecules, 2025Plant-derived squalane protected human dermal fibroblasts against UVA-induced damage by counteracting ROS formation, suppressing apoptosis-related proteins p53, caspase-3, caspase-9, and PARP, and restoring the pro-survival p-Akt/mTOR pathway.
Antioxidants, 2025The emollient V0034CR significantly reduced TEWL compared to vehicle and vehicle plus glycerol, and significantly increased corneometry scores compared to vehicle and vehicle plus petrolatum in healthy volunteers with dry skin, demonstrating combined barrier function improvement from petrolatum and hydration improvement from glycerol.
Journal of Cosmetic Dermatology, 2020Ten days of treatment with a cream containing 20% glycerin significantly increased skin hydration measured by corneometer values in 17 healthy volunteers compared to a placebo cream, but showed no influence on transepidermal water loss or skin sensitivity to an irritating surfactant.
International Journal of Cosmetic Science, 2001Niacinamide/glycerin body moisturizers provided better rapid and prolonged improvement of cosmetic xerosis through functional improvement of stratum corneum barrier function compared to no treatment and conventional moisturizers in female subjects.
Journal of Drugs in Dermatology, 2012A 1-year clinical study on human facial skin demonstrated that Zingiber officinale (L.) Rose extract inhibits the UV-induced decrease in skin elasticity and prevents or improves wrinkle formation around the eye.
Archives of Dermatological Research, 2008Ginger extract transethosomal hydrogel improved skin permeability, sustained drug release, and exhibited significant inhibition of edema swelling along with reduced reactive oxygen species and prostaglandin E2 compared to free ginger extract hydrogel and ketoprofen gel in a rat-paw edema model.
International Journal of Nanomedicine, 2023Topical delivery of ginger extract-loaded nanoemulsions significantly reduced arthritic symptoms, paw edema inhibition by 27.7%, and inflammatory cytokines in RA-induced rats compared to the negative control.
Journal of Pharmaceutical Sciences, 2023
Ingredients
Water, Squalane, Glycerin, Dimethicone, Pentylene Glycol, Ammonium Acryloyldimethyltaurate Vp Copolymer, Lactococcus Lysate Ferment, Caprylic Capric Triglyceride, Phenoxyethanol, Caprylyl Glycol, Dimethiconol, Chondrus Crispus Extract, Allantoin, Bisabolol, Glycine Soja Soybean Sterols, Linoleic Acid, Sodium Phytate, Lecithin, Sodium Hydroxide, Sodium Hyaluronate, Lactic Acid, Lepidium Sativum Extract Sprout, Sodium Chloride, Sodium Benzoate, Citric Acid, Zingiber Officinale Root Extract
Behind this fit score
Lovi calculates every fit score from the full ingredient list with brand-independent rules our dermatologists and cosmetic chemists build and review, and personalizes every pick with AI trained on the real results of millions of users. Lovi trains its fit score models on a proprietary dataset built from more than 10,000 expert-labeled products and more than 100,000 simulated examples, following an internally consistent methodology presented at Cosmoprof, AMWC, and Skin of Color Update.
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Co-founder, Medical Director
Cosmetic chemist, cosmetologist, aesthetic products developer
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Co-founder, CEO and CTO
PhD in computer science, 3x US patent holder, ex-Google, ex-Yandex
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Dr. Sofía Perea Pérez, MD, MSc
Medical Board
Aesthetic medicine practitioner, MSc in Longevity and Anti-Aging Medicine
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Medical Board
Specialist dermatologist, MBBS, MD, IFAAD
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Medical Board
Cosmetic chemist, SCS, IFSCC member
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Medical Board, Medical Advisor
Dermatology MD
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Elina Nazarenko, MD
Medical Board
Dermatology and diagnostic consultant
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Victoria Derkova, MS
Medical Board
Cosmetic chemist, cosmetic development technologist
How does it fit your skin?
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