# Biossance Squalane + Ectoin Overnight Rescue for dry skin

**Lovi Fit: High fit for dry skin.**
Dry Skin Fit: High · Effectiveness: High · Safety: Excellent.

Page: https://lovi.care/skincare/ae/p/biossance/squalane-ectoin-overnight-rescue/for/dry-skin

The Lovi Fit is the same in every country; only the stores and prices differ, and the ones here are for the United Arab Emirates.

Brand: [Biossance](https://lovi.care/skincare/ae/brands/biossance)
Category: [Moisturizers and moisturizing serums](https://lovi.care/skincare/ae/best/moisturizers)

This fit is calculated for the concerns frequently associated with dry skin: flakiness, tightness, dehydration, fine lines, and wrinkles. For scores based on a full skin profile (12D face scan, goals, preferences), use the Lovi app.

One of the best moisturizers for dry skin.

## Why this fit

- Highly suitable for your dry skin as squalane and glycerin provide excellent emollient and humectant actions to hydrate and support your skin barrier. Ectoin further enhances barrier resilience and offers protection against environmental stressors, addressing your dry or flaky skin concerns.
- The formulation includes Shorea Stenoptera Seed Butter and jojoba esters, which offer additional nourishment and emollience beneficial for dry skin.
- The safety profile is excellent, with no risks of irritation due to the absence of harsh ingredients and the inclusion of soothing components like Ectoin and Squalane.

## Fit by skin type

- [Oily skin](https://lovi.care/skincare/ae/p/biossance/squalane-ectoin-overnight-rescue/for/oily-skin): Average
- [Dry skin](https://lovi.care/skincare/ae/p/biossance/squalane-ectoin-overnight-rescue/for/dry-skin): High (this page)
- [Combination skin](https://lovi.care/skincare/ae/p/biossance/squalane-ectoin-overnight-rescue/for/combination-skin): Average
- [Sensitive skin](https://lovi.care/skincare/ae/p/biossance/squalane-ectoin-overnight-rescue/for/sensitive-skin): High
- [Acne-prone skin](https://lovi.care/skincare/ae/p/biossance/squalane-ectoin-overnight-rescue/for/acne-prone-skin): Average
- [Skin with dark spots](https://lovi.care/skincare/ae/p/biossance/squalane-ectoin-overnight-rescue/for/dark-spots): Average
- [Mature skin](https://lovi.care/skincare/ae/p/biossance/squalane-ectoin-overnight-rescue/for/mature-skin): High
- [Dry sensitive skin](https://lovi.care/skincare/ae/p/biossance/squalane-ectoin-overnight-rescue/for/dry-sensitive-skin): High
- [Oily acne-prone skin](https://lovi.care/skincare/ae/p/biossance/squalane-ectoin-overnight-rescue/for/oily-acne-prone-skin): Average

## Key ingredients

Squalane, Ectoin, Glycerin, Shorea Stenoptera Seed Butter, Acetyl Hexapeptide-8

## What the research says

- A single application of a moisturizing fluid containing hyaluronic acid 1%, glycerin 5%, and Centella asiatica stem cells extract significantly increased skin hydration by 29% and reduced transepidermal water loss at 24 hours compared to baseline and an untreated control site in twenty healthy women. ([Clinical, Cosmetic and Investigational Dermatology, 2017](https://pubmed.ncbi.nlm.nih.gov/28860834/))
- Topical formulations containing 3.75% glycerol and 1.25% hydrolyzed jojoba esters produced significantly lower evaporative TEWL values compared to glycerol alone at 8 and 24 hours posttreatment in human subjects. ([Journal of Cosmetic Dermatology, 2008](https://pubmed.ncbi.nlm.nih.gov/19146603/))
- Squalane at 0.005-0.015% counteracts UVA-induced oxidative stress, inflammation, and collagen metabolism inhibition while stimulating fibroblast migration in human dermal fibroblasts. ([Molecules, 2025](https://pubmed.ncbi.nlm.nih.gov/40363772/))
- Plant-derived squalane protected human dermal fibroblasts against UVA-induced damage by counteracting ROS formation, suppressing apoptosis-related proteins p53, caspase-3, caspase-9, and PARP, and restoring the pro-survival p-Akt/mTOR pathway. ([Antioxidants, 2025](https://pubmed.ncbi.nlm.nih.gov/40722956/))
- Combining ectoine and mannitol with UV filters significantly improved protection of squalene oxidation, catalase activity, and trans-UCA compared to UV filters alone in 10 subjects on irradiated areas. ([Journal of Cosmetic Dermatology, 2024](https://pubmed.ncbi.nlm.nih.gov/37539499/))
- Topical 7% ectoine during serial 1064-nm Nd:YAG laser therapy produced a greater reduction in skin erythema, improved stratum corneum hydration, reduced transepidermal water loss, and decreased low-echogenic pixels in thirty participants compared to a vehicle control. ([Biomedicines, 2026](https://pubmed.ncbi.nlm.nih.gov/42792808/))
- Regular application of a novel anti-ageing cream containing hyaluronic acid, ectoin, and botanical actives significantly reduced wrinkle depth and length in the periorbital area while demonstrating very good skin tolerance. ([Polymers, 2023](https://pubmed.ncbi.nlm.nih.gov/37896378/))
- The emollient V0034CR significantly reduced TEWL compared to vehicle and vehicle plus glycerol, and significantly increased corneometry scores compared to vehicle and vehicle plus petrolatum in healthy volunteers with dry skin, demonstrating combined barrier function improvement from petrolatum and hydration improvement from glycerol. ([Journal of Cosmetic Dermatology, 2020](https://pubmed.ncbi.nlm.nih.gov/31532576/))
- Ten days of treatment with a cream containing 20% glycerin significantly increased skin hydration measured by corneometer values in 17 healthy volunteers compared to a placebo cream, but showed no influence on transepidermal water loss or skin sensitivity to an irritating surfactant. ([International Journal of Cosmetic Science, 2001](https://pubmed.ncbi.nlm.nih.gov/18498456/))
- Niacinamide/glycerin body moisturizers provided better rapid and prolonged improvement of cosmetic xerosis through functional improvement of stratum corneum barrier function compared to no treatment and conventional moisturizers in female subjects. ([Journal of Drugs in Dermatology, 2012](https://pubmed.ncbi.nlm.nih.gov/22206073/))
- Treatment with cross-linked hyaluronic acid-based microneedle patches combined with acetyl hexapeptide-8 or epidermal growth factor significantly improved wrinkles and skin hydration compared to the patch alone in Korean females over 29 days. ([Annals of Dermatology, 2019](https://pubmed.ncbi.nlm.nih.gov/33911590/))
- Argireline treatment twice daily for 4 weeks produced a significant anti-wrinkle effect with 48.9% total efficacy and decreased skin roughness in Chinese subjects compared with 0% efficacy and no decrease in roughness in the placebo group. ([American Journal of Clinical Dermatology, 2013](https://pubmed.ncbi.nlm.nih.gov/23417317/))
- Acetyl hexapeptide-3 and tripeptide-10 citrulline demonstrated antiwrinkle efficacy and decreased transepidermal water loss in twenty-four healthy volunteers compared to control groups, though synergistic effects between the two peptides remained unclear. ([Journal of Cosmetic Dermatology, 2017](https://pubmed.ncbi.nlm.nih.gov/28150423/))

## What reviewers say

Most users report waking up to soft, plump, and soothed skin without irritation. Those with oily or acne-prone skin occasionally find the formula too rich. This summary is based on a very large amount of data and should definitely be taken into account.

- Liked: Deeply hydrating (mostly mentioned)
- Liked: Absorbs well (often mentioned)
- Liked: Plumps and softens (often mentioned)
- Liked: Soothes sensitive skin (often mentioned)
- Disliked: High price point (sometimes noted)
- Disliked: Heavy or greasy (rarely noted)
- Disliked: Jar packaging (rarely noted)
- Disliked: May cause breakouts (rarely noted)

## How to apply

- Could be used as part of your AM or PM routine. Start using it 3 times a week and work your way up to daily use.
- Apply your moisturizer after your toner and before your sunscreen in the morning. At night, use it as the final step after your serum.
- Gently press a small amount of the moisturizer into your skin. Avoid rubbing to keep your dry skin happy.
- Apply the moisturizer on slightly damp skin to help lock in extra hydration. This is great for soothing dry and flaky areas .
- Avoid the sensitive eye area and do a patch test before your first use .
- Video: https://storage.pora.ai/2f72f5d69f07beeafc30237f829efbff.mp4

## Questions and answers

### What makes Biossance Squalane + Ectoin Overnight Rescue a great fit for dry skin?

Biossance Squalane + Ectoin Overnight Rescue is a great fit because squalane, glycerin, and seed butter hydrate dry skin and support the skin barrier. Ectoin adds extra barrier protection against environmental stressors to help keep flaky skin calm and comfortable.

### Which ingredients make this cream a good fit for dry skin?

Squalane, ectoin, glycerin, Shorea Stenoptera seed butter, and jojoba esters make this cream a great fit because they hydrate, nourish, and protect your dry skin while supporting your skin barrier. Ectoin and squalane also help ensure a very safe, soothing experience without any harsh irritation.

### What does Squalane do for dry skin?

Squalane helps keep dry skin soft and smooth by acting as a hydrating agent that locks in moisture and prevents water loss. It is unlikely to cause irritation and may protect the skin from damage while improving overall hydration.
Sources: [Advances in Food and Nutrition Research, 2012](https://pubmed.ncbi.nlm.nih.gov/22361190/), [Molecules, 2009](https://pubmed.ncbi.nlm.nih.gov/19169201/)

### What does Ectoin do for dry skin?

Ectoin helps dry skin by locking in moisture to keep it soft and smooth while strengthening the outer barrier to stop water from escaping. It may also calm redness and ease skin sensitivity.
Sources: [Clinics in Dermatology, 2008](https://pubmed.ncbi.nlm.nih.gov/18691511/), [European Journal of Dermatology, 2025](https://pubmed.ncbi.nlm.nih.gov/40742058/)

### Where does this cream go in a skincare routine for dry skin?

This cream goes in the evening routine as a treatment step before your moisturizer, helping to lock in hydration and support your skin barrier. It is very gentle and unlikely to cause irritation on dry skin.
Sources: [The Journal of Dermatological Treatment, 2022](https://pubmed.ncbi.nlm.nih.gov/32239984/)

### Can I use this cream with retinol, and in what order?

You can use this treatment with retinol by applying the treatment first and following it with your retinol, or by using the treatment in your morning routine and retinol at night. Using a barrier-enhancing moisturizer helps improve skin tolerance and reduces the irritation often caused by retinoids.
Sources: [Cutis, 2006](https://pubmed.ncbi.nlm.nih.gov/17121065/), [Journal of Drugs in Dermatology, 2012](https://pubmed.ncbi.nlm.nih.gov/22648223/)

### How often should I use this cream?

This moisturizing treatment is designed for evening use as part of your nightly routine for dry skin. Daily application helps lock in moisture, keeps dry or flaky skin smooth, and is unlikely to cause irritation.
Sources: [Health Science Reports, 2021](https://pubmed.ncbi.nlm.nih.gov/34141902/), [Journal of Cosmetic Dermatology, 2020](https://pubmed.ncbi.nlm.nih.gov/32141711/)

### Can this cream clog pores, cause breakouts or purging for dry skin?

This cream is unlikely to cause breakouts on dry skin because it features soothing ingredients and a very low risk of clogged pores according to reviewers. It is designed to deeply hydrate and nourish dry skin without heavy or greasy side effects.

### Can I use this cream around the eyes or on my body?

This cream is well-suited for the thin skin around the eyes and body because its gentle, nourishing formula keeps dry areas soft and hydrated. It has an excellent safety profile with soothing ingredients that are unlikely to cause irritation.
Sources: [Polymers, 2023](https://pubmed.ncbi.nlm.nih.gov/37896378/)

### Is this cream fragrance-free and alcohol-free?

Yes, it has no fragrance and no drying alcohol.

## Alternatives for dry skin

- [Allies of Skin Peptides & Antioxidants Firming Daily Treatment](https://lovi.care/skincare/ae/p/allies-of-skin/peptides-and-antioxidants-firming-daily-treatment/for/dry-skin) — High fit — AED 230.55 at Amazon
- [Medi-Peel Peptide 9 Volume Tox Cream](https://lovi.care/skincare/ae/p/medi-peel/peptide-9-volume-tox-cream/for/dry-skin) — High fit — AED 84.55 at Amazon
- [StriVectin SD Advanced Plus Intensive Moisturizing Concentrate](https://lovi.care/skincare/ae/p/strivectin/sd-advanced-plus-intensive-moisturizing-concentrate/for/dry-skin) — High fit — AED 199.00 at Amazon

## Pairs well with

- Cleanser: [CeraVe Hydrating Cleanser](https://lovi.care/skincare/ae/p/cerave/hydrating-facial-cleanser/for/dry-skin) — Superior fit — AED 32.95 at Amazon
- SPF: [Dr.G Green Mild Up Sun+](https://lovi.care/skincare/ae/p/dr-g/green-mild-up-sun/for/dry-skin) — Superior fit — AED 81.00 at Amazon
- Pre-Cleanser: [MISSHA Ultra Hyalon Cleansing Cream](https://lovi.care/skincare/ae/p/missha/ultra-hyalon-cleansing-cream/for/dry-skin) — Superior fit — AED 35.29 at Amazon

## Where to buy

- Amazon.ae: AED 278.05 (https://www.amazon.ae/dp/B0CVR4G674?tag=lovi00-21&linkCode=osi&th=1&psc=1)
- Lookfantastic: AED 265.00 (https://www.lookfantastic.ae/p/biossance-squalane-and-ectoin-overnight-rescue-50ml/15065083/)
Prices checked 28 Oct – 5 Nov 2026.

## Ingredients

Water, Glycerin, Squalane, Shorea Stenoptera Seed Butter, Caprylic Capric Triglyceride, C12-16 Alcohols, Sodium Acrylates Copolymer, Ectoin, Jojoba Esters, Acetyl Hexapeptide-8, Magnesium Chloride, Palmitic Acid, Hydrogenated Lecithin, Hydroxyethyl Acrylate Sodium Acryloyldimethyl Taurate Copolymer, Lecithin, Sorbitan Isostearate, Tocopherol, Caprylyl Glycol, Ethylhexylglycerin, Phenoxyethanol, Sodium Gluconate
## About the Lovi Fit

Lovi: Unbiased, science-based skincare AI trained on real user outcomes.

Lovi calculates every fit score from the full ingredient list with brand-independent rules its dermatologists and cosmetic chemists build and review, and personalizes every pick with AI trained on the real results of millions of users. Lovi trains its fit score models on a proprietary dataset built from more than 10,000 expert-labeled products and more than 100,000 simulated examples, following an internally consistent methodology presented at Cosmoprof, AMWC, and Skin of Color Update. Levels from best to worst: Superior, High, Average, Low, Caution, Warning.

Behind this fit score: Nadia Kapleva, MS (Co-founder, Medical Director); Alexey Shagraev, PhD (Co-founder, CEO and CTO); Dr. Sofía Perea Pérez, MD, MSc (Medical Board); Aishani Shah, MD (Medical Board); Asya Zubkova, MS (Medical Board); Hanna Kurets, MD (Medical Board, Medical Advisor); Elina Nazarenko, MD (Medical Board); Victoria Derkova, MS (Medical Board).

Page built Nov 8, 2026.

More from Lovi: https://lovi.care/skincare/llms.txt

## This page in other countries

- United States: https://lovi.care/skincare/p/biossance/squalane-ectoin-overnight-rescue/for/dry-skin
- United Kingdom: https://lovi.care/skincare/uk/p/biossance/squalane-ectoin-overnight-rescue/for/dry-skin
- Ireland: https://lovi.care/skincare/ie/p/biossance/squalane-ectoin-overnight-rescue/for/dry-skin
- Germany: https://lovi.care/skincare/de/p/biossance/squalane-ectoin-overnight-rescue/for/dry-skin
- France: https://lovi.care/skincare/fr/p/biossance/squalane-ectoin-overnight-rescue/for/dry-skin
- Italy: https://lovi.care/skincare/it/p/biossance/squalane-ectoin-overnight-rescue/for/dry-skin
- Netherlands: https://lovi.care/skincare/nl/p/biossance/squalane-ectoin-overnight-rescue/for/dry-skin
- Spain: https://lovi.care/skincare/es/p/biossance/squalane-ectoin-overnight-rescue/for/dry-skin
- Canada: https://lovi.care/skincare/ca/p/biossance/squalane-ectoin-overnight-rescue/for/dry-skin
- Australia: https://lovi.care/skincare/au/p/biossance/squalane-ectoin-overnight-rescue/for/dry-skin
- Singapore: https://lovi.care/skincare/sg/p/biossance/squalane-ectoin-overnight-rescue/for/dry-skin
- Saudi Arabia: https://lovi.care/skincare/sa/p/biossance/squalane-ectoin-overnight-rescue/for/dry-skin
- United Arab Emirates: https://lovi.care/skincare/ae/p/biossance/squalane-ectoin-overnight-rescue/for/dry-skin (this page)