# BIOEFFECT EGF Serum for oily acne-prone skin

**Lovi Fit: High fit for oily acne-prone skin.**
Oily Skin Fit: High · Effectiveness: High · Safety: High.

Page: https://lovi.care/skincare/ae/p/bioeffect/egf-serum/for/oily-acne-prone-skin

The Lovi Fit is the same in every country; only the stores and prices differ, and the ones here are for the United Arab Emirates.

Brand: [BIOEFFECT](https://lovi.care/skincare/ae/brands/bioeffect)
Category: [Serums and treatments](https://lovi.care/skincare/ae/best/serums)

This fit is calculated for the concerns frequently associated with oily acne-prone skin: shine, breakouts, blemishes, and enlarged pores. For scores based on a full skin profile (12D face scan, goals, preferences), use the Lovi app.

A great choice for oily acne-prone skin; a few serums fit it even better.

## Why this fit

- Highly suitable for your oily skin, the presence of Glycerin and Sodium Hyaluronate provides excellent humectant action, hydrating without adding excess oil.
- The high concentrations of Rh-Oligopeptide-1 and Barley Sh-Oligopeptide-1 offer significant skin regeneration benefits for plumping and minimizing fine lines and wrinkles.
- The formula is safe for your oily skin, with no risks of irritation due to the absence of prohibited or harsh ingredients.

## Fit by skin type

- [Oily skin](https://lovi.care/skincare/ae/p/bioeffect/egf-serum/for/oily-skin): High
- [Dry skin](https://lovi.care/skincare/ae/p/bioeffect/egf-serum/for/dry-skin): Superior
- [Combination skin](https://lovi.care/skincare/ae/p/bioeffect/egf-serum/for/combination-skin): High
- [Sensitive skin](https://lovi.care/skincare/ae/p/bioeffect/egf-serum/for/sensitive-skin): High
- [Acne-prone skin](https://lovi.care/skincare/ae/p/bioeffect/egf-serum/for/acne-prone-skin): High
- [Skin with dark spots](https://lovi.care/skincare/ae/p/bioeffect/egf-serum/for/dark-spots): High
- [Mature skin](https://lovi.care/skincare/ae/p/bioeffect/egf-serum/for/mature-skin): Superior
- [Dry sensitive skin](https://lovi.care/skincare/ae/p/bioeffect/egf-serum/for/dry-sensitive-skin): Superior
- [Oily acne-prone skin](https://lovi.care/skincare/ae/p/bioeffect/egf-serum/for/oily-acne-prone-skin): High (this page)

## Key ingredients

Rh-Oligopeptide-1, Glycerin, Sodium Hyaluronate, Hordeum Vulgare Seed Extract, Tromethamine

## What the research says

- A single application of a moisturizing fluid containing hyaluronic acid 1%, glycerin 5%, and Centella asiatica stem cells extract significantly increased skin hydration by 29% and reduced transepidermal water loss at 24 hours compared to baseline and an untreated control site in twenty healthy women. ([Clinical, Cosmetic and Investigational Dermatology, 2017](https://pubmed.ncbi.nlm.nih.gov/28860834/))
- Ketorolac tromethamine poloxamer hydrogel provided sufficient bioavailability to reach the site of action with anti-inflammatory efficacy and no visual skin irritation in volunteers. ([Pharmaceutical Research, 2017](https://pubmed.ncbi.nlm.nih.gov/28540502/))
- Topical epidermal growth factor combined with silver sulfadiazine accelerated the rate of epidermal regeneration and significantly decreased healing time by approximately 1 to 1.5 days across all stages of healing in skin-graft-donor sites of 12 patients compared to silver sulfadiazine alone. ([The New England Journal of Medicine, 1989](https://pubmed.ncbi.nlm.nih.gov/2659995/))
- Topical recombinant human epidermal growth factor combined with ablative fractional carbon dioxide laser significantly improved striae surface texture and showed significantly greater participant satisfaction regarding marked improvement compared to ablative fractional carbon dioxide laser combined with Aloe vera gel in patients with striae alba. ([Lasers in Surgery and Medicine, 2020](https://pubmed.ncbi.nlm.nih.gov/30614013/))
- Topical EGF combined with fractional CO2 laser significantly improves the clinical appearance of atrophic acne scars and decreases skin pigmentation compared to fractional CO2 laser alone in patients with atrophic acne scars. ([The Journal of Clinical and Aesthetic Dermatology, 2022](https://pubmed.ncbi.nlm.nih.gov/35942017/))
- The emollient V0034CR significantly reduced TEWL compared to vehicle and vehicle plus glycerol, and significantly increased corneometry scores compared to vehicle and vehicle plus petrolatum in healthy volunteers with dry skin, demonstrating combined barrier function improvement from petrolatum and hydration improvement from glycerol. ([Journal of Cosmetic Dermatology, 2020](https://pubmed.ncbi.nlm.nih.gov/31532576/))
- Ten days of treatment with a cream containing 20% glycerin significantly increased skin hydration measured by corneometer values in 17 healthy volunteers compared to a placebo cream, but showed no influence on transepidermal water loss or skin sensitivity to an irritating surfactant. ([International Journal of Cosmetic Science, 2001](https://pubmed.ncbi.nlm.nih.gov/18498456/))
- Niacinamide/glycerin body moisturizers provided better rapid and prolonged improvement of cosmetic xerosis through functional improvement of stratum corneum barrier function compared to no treatment and conventional moisturizers in female subjects. ([Journal of Drugs in Dermatology, 2012](https://pubmed.ncbi.nlm.nih.gov/22206073/))
- Topical application of 0.1% hyaluronic acid formulations of different molecular weights led to significant improvements in skin hydration and elasticity, with low-molecular-weight formulations also significantly reducing wrinkle depth in seventy-six female subjects compared to a vehicle control. ([Journal of Drugs in Dermatology, 2011](https://pubmed.ncbi.nlm.nih.gov/22052267/))
- Topical application of hyaluronic acid in conjunction with free gingival graft significantly reduced donor site postoperative pain until day 7 compared to normal saline, with no significant differences in graft dimensions or patient satisfaction. ([Clinical Oral Investigations, 2022](https://pubmed.ncbi.nlm.nih.gov/34623507/))
- Treatment with a hyaluronic acid-containing mouth rinse or topical gel led to significant lesion reduction, pain relief, and normalization of lesion color in adult patients with minor recurrent aphthous stomatitis, with the gel formulation showing an earlier healing onset at 3 days. ([BMC Oral Health, 2019](https://pubmed.ncbi.nlm.nih.gov/31311529/))
- Lidocaine at 20% and lidocaine 10% with trometamol provided effective pain control comparable to lidocaine/prilocaine in healthy adults after a 60-minute exposure, while propylene glycol did not accelerate the onset of analgesia. ([Journal of Pain Research, 2017](https://pubmed.ncbi.nlm.nih.gov/28546768/))
- A Tris/Arg-formulated cleanser significantly decreased noninflammatory and inflammatory acne and pore size with keratotic plugs compared to an AEC/AC cleanser in male Thai subjects with mild to moderate acne over 4 weeks. ([Journal of Cosmetic Dermatology, 2020](https://pubmed.ncbi.nlm.nih.gov/31347768/))
- Tertiary-butyl ammonium and TRIS salts of NSAIDs form supramolecular gels that exhibit biocompatibility and equal anti-inflammatory efficacy to parent drugs, with FLR.TRIS successfully treating inflamed skin in a mice model. ([Chemistry, 2017](https://pubmed.ncbi.nlm.nih.gov/28895213/))

## What reviewers say

Users with dry, mature, or dehydrated skin highly praise this serum for its deep hydration, plumping effects, and ability to reduce fine lines, resulting in a radiant complexion. Some users with oily or combination skin find the texture sticky or heavy.

- Liked: Hydrating and plumping (mostly mentioned)
- Liked: Radiant glow (often mentioned)
- Liked: Reduces fine lines (often mentioned)
- Disliked: Expensive product (often mentioned)
- Liked: Improves texture (sometimes noted)
- Disliked: Sticky texture (sometimes noted)
- Disliked: Too heavy (rarely noted)

## How to apply

- Could be used as part of your PM routine. Start 3 times a week and build up to daily use if your skin tolerates it well.
- Apply your serum after cleansing and toning, but before putting on your moisturizer.
- Gently press 2 to 3 drops of the serum into your skin and let it absorb for a minute.
- Apply the serum on clean, dry skin to help manage your blemishes safely.
- Do a patch test before your first use and avoid the delicate eye area.
- Video: https://storage.pora.ai/c879dda8655a61c19d3d8c9ebad6b06d.mp4

## Questions and answers

### What makes BIOEFFECT EGF Serum a great fit for oily acne-prone skin?

BIOEFFECT EGF Serum is a great fit because glycerin and sodium hyaluronate hydrate oily skin without adding excess oil, while growth factors like Rh-Oligopeptide-1 help regenerate skin. The formula is also very safe for this skin type and is unlikely to cause irritation.
Sources: [Clinical, Cosmetic and Investigational Dermatology, 2017](https://pubmed.ncbi.nlm.nih.gov/28860834/)

### Which ingredients make this serum a good fit for oily acne-prone skin?

Glycerin and Sodium Hyaluronate make this serum a great fit because they hydrate your skin without adding excess oil. The formula is also very safe and unlikely to cause irritation.
Sources: [Clinical, Cosmetic and Investigational Dermatology, 2017](https://pubmed.ncbi.nlm.nih.gov/28860834/)

### What does EGF do for oily acne-prone skin?

EGF helps calm redness and breakouts, and it may improve the look of acne scars on oily skin. It also supports the skin barrier while increasing skin water and oil balance.
Sources: [Clinical, Cosmetic and Investigational Dermatology, 2023](https://pubmed.ncbi.nlm.nih.gov/37841061/), [International Journal of Dermatology, 2014](https://pubmed.ncbi.nlm.nih.gov/24962549/)

### What does Glycerin do for oily acne-prone skin?

Glycerin helps keep oily acne-prone skin hydrated without feeling heavy. It draws moisture into the skin while supporting the skin barrier so it stays soft and balanced.
Sources: [The British Journal of Dermatology, 2008](https://pubmed.ncbi.nlm.nih.gov/18510666/), [Clinical, Cosmetic and Investigational Dermatology, 2017](https://pubmed.ncbi.nlm.nih.gov/28860834/)

### Where does this serum go in a skincare routine for oily acne-prone skin?

This treatment serum goes in your evening skincare routine, applied after cleansing and before moisturizing. Using it at night keeps things simple and avoids extra safety concerns around sun exposure.

### Can I use this serum with retinol, and in what order?

You can use this serum with retinol by applying the serum after your retinol treatment, as the formula is safe and hydrating for your skin without adding excess oil. Using a gentle hydrating routine alongside your treatments helps keep your skin calm and reduces potential discomfort.
Sources: [Journal of Cosmetic Dermatology, 2024](https://pubmed.ncbi.nlm.nih.gov/38102855/), [Clinical, Cosmetic and Investigational Dermatology, 2017](https://pubmed.ncbi.nlm.nih.gov/28860834/)

### How often should I use this serum?

You can use this treatment in your evening routine for simplicity and extra safety around sun exposure. Its hydrating ingredients add moisture without extra oil, making it safe and gentle for oily skin.
Sources: [Clinical, Cosmetic and Investigational Dermatology, 2017](https://pubmed.ncbi.nlm.nih.gov/28860834/)

### Can this serum clog pores, cause breakouts or purging for oily acne-prone skin?

This serum is a great fit for your oily acne-prone skin because glycerin and sodium hyaluronate hydrate your skin without adding excess oil. The formula is also safe for your skin, as it contains no harsh or prohibited ingredients that would likely cause irritation, breakouts, or clogged pores.
Sources: [Clinical, Cosmetic and Investigational Dermatology, 2017](https://pubmed.ncbi.nlm.nih.gov/28860834/)

## Alternatives for oily acne-prone skin

- [Clinique Fresh Pressed Daily Booster with Pure Vitamin C 10%](https://lovi.care/skincare/ae/p/clinique/fresh-pressed-daily-booster-with-pure-vitamin-c-10/for/oily-acne-prone-skin) — Superior fit — AED 365.22 at Amazon
- [Neogen Dermalogy Real Vitamin C Serum](https://lovi.care/skincare/ae/p/neogen-dermalogy/real-vitamin-c-serum/for/oily-acne-prone-skin) — Superior fit — AED 89.30 at Amazon
- [NEOGEN DERMALOGY REAL VITA C SERUM](https://lovi.care/skincare/ae/p/neogen-dermalogy/real-vita-c-serum/for/oily-acne-prone-skin) — High fit — AED 89.30 at Amazon

## Pairs well with

- Cleanser: [IS Clinical Cleansing Complex](https://lovi.care/skincare/ae/p/is-clinical/cleansing-complex/for/oily-acne-prone-skin) — Superior fit — AED 138.20 at Amazon
- Hydrating Toner: [Paula's Choice Pore-Reducing Toner](https://lovi.care/skincare/ae/p/paula-s-choice/skin-balancing-pore-reducing-toner/for/oily-acne-prone-skin) — Superior fit — AED 145.00 at Amazon
- Moisturizer: [COSRX Oil-Free Ultra-Moisturizing Lotion with Birch Sap](https://lovi.care/skincare/ae/p/cosrx/oil-free-ultra-moisturizing-lotion-with-birch-sap/for/oily-acne-prone-skin) — Superior fit — AED 33.40 at Amazon

## Where to buy

No store in United Arab Emirates has a checked price for this product, so the page shows none.

## Ingredients

Glycerin, Water, Sodium Hyaluronate, Tromethamine, Sodium Chloride, Hordeum Vulgare Seed Extract, Rh-Oligopeptide-1 Barley Sh-Oligopeptide-1
## About the Lovi Fit

Lovi: Unbiased, science-based skincare AI trained on real user outcomes.

Lovi calculates every fit score from the full ingredient list with brand-independent rules its dermatologists and cosmetic chemists build and review, and personalizes every pick with AI trained on the real results of millions of users. Lovi trains its fit score models on a proprietary dataset built from more than 10,000 expert-labeled products and more than 100,000 simulated examples, following an internally consistent methodology presented at Cosmoprof, AMWC, and Skin of Color Update. Levels from best to worst: Superior, High, Average, Low, Caution, Warning.

Behind this fit score: Nadia Kapleva, MS (Co-founder, Medical Director); Alexey Shagraev, PhD (Co-founder, CEO and CTO); Dr. Sofía Perea Pérez, MD, MSc (Medical Board); Aishani Shah, MD (Medical Board); Asya Zubkova, MS (Medical Board); Hanna Kurets, MD (Medical Board, Medical Advisor); Elina Nazarenko, MD (Medical Board); Victoria Derkova, MS (Medical Board).

Page built Nov 8, 2026.

More from Lovi: https://lovi.care/skincare/llms.txt

## This page in other countries

- United States: https://lovi.care/skincare/p/bioeffect/egf-serum/for/oily-acne-prone-skin
- United Kingdom: https://lovi.care/skincare/uk/p/bioeffect/egf-serum/for/oily-acne-prone-skin
- Ireland: https://lovi.care/skincare/ie/p/bioeffect/egf-serum/for/oily-acne-prone-skin
- Germany: https://lovi.care/skincare/de/p/bioeffect/egf-serum/for/oily-acne-prone-skin
- France: https://lovi.care/skincare/fr/p/bioeffect/egf-serum/for/oily-acne-prone-skin
- Italy: https://lovi.care/skincare/it/p/bioeffect/egf-serum/for/oily-acne-prone-skin
- Netherlands: https://lovi.care/skincare/nl/p/bioeffect/egf-serum/for/oily-acne-prone-skin
- Spain: https://lovi.care/skincare/es/p/bioeffect/egf-serum/for/oily-acne-prone-skin
- Canada: https://lovi.care/skincare/ca/p/bioeffect/egf-serum/for/oily-acne-prone-skin
- Australia: https://lovi.care/skincare/au/p/bioeffect/egf-serum/for/oily-acne-prone-skin
- Singapore: https://lovi.care/skincare/sg/p/bioeffect/egf-serum/for/oily-acne-prone-skin
- Saudi Arabia: https://lovi.care/skincare/sa/p/bioeffect/egf-serum/for/oily-acne-prone-skin
- United Arab Emirates: https://lovi.care/skincare/ae/p/bioeffect/egf-serum/for/oily-acne-prone-skin (this page)