# Avène Cleanance Comedomed for dry sensitive skin

**Lovi Fit: Caution fit for dry sensitive skin.**
Dry Skin Fit: Caution · Effectiveness: High · Safety: Risky.

Page: https://lovi.care/skincare/ae/p/avene/cleanance-comedomed/for/dry-sensitive-skin

The Lovi Fit is the same in every country; only the stores and prices differ, and the ones here are for the United Arab Emirates.

Brand: [Avène](https://lovi.care/skincare/ae/brands/avene)
Category: [Serums and treatments](https://lovi.care/skincare/ae/best/serums)

This fit is calculated for the concerns frequently associated with dry sensitive skin: flakiness, tightness, redness, fine lines, and wrinkles. For scores based on a full skin profile (12D face scan, goals, preferences), use the Lovi app.

A poor match for dry sensitive skin; the serums alongside fit it better.

## Why this fit

- Offers moderate exfoliation for your dry and sensitive skin due to the presence of salicylic acid and glycolic acid, which can cause dryness and irritation, even with glycerin's humectant action.
- While the formula is free of harsh ingredients and safe for your dry and sensitive skin, the exfoliating acids may not be ideal for addressing flakiness.

## Fit by skin type

- [Oily skin](https://lovi.care/skincare/ae/p/avene/cleanance-comedomed/for/oily-skin): Average
- [Dry skin](https://lovi.care/skincare/ae/p/avene/cleanance-comedomed/for/dry-skin): Caution
- [Combination skin](https://lovi.care/skincare/ae/p/avene/cleanance-comedomed/for/combination-skin): High
- [Sensitive skin](https://lovi.care/skincare/ae/p/avene/cleanance-comedomed/for/sensitive-skin): Average
- [Acne-prone skin](https://lovi.care/skincare/ae/p/avene/cleanance-comedomed/for/acne-prone-skin): Average
- [Skin with dark spots](https://lovi.care/skincare/ae/p/avene/cleanance-comedomed/for/dark-spots): Average
- [Mature skin](https://lovi.care/skincare/ae/p/avene/cleanance-comedomed/for/mature-skin): Average
- [Dry sensitive skin](https://lovi.care/skincare/ae/p/avene/cleanance-comedomed/for/dry-sensitive-skin): Caution (this page)
- [Oily acne-prone skin](https://lovi.care/skincare/ae/p/avene/cleanance-comedomed/for/oily-acne-prone-skin): High

## Key ingredients

Salicylic Acid, Glycolic Acid, Zinc Gluconate, Silybum Marianum Fruit Extract, Pumpkin Seed Oil

## What the research says

- A single application of a moisturizing fluid containing hyaluronic acid 1%, glycerin 5%, and Centella asiatica stem cells extract significantly increased skin hydration by 29% and reduced transepidermal water loss at 24 hours compared to baseline and an untreated control site in twenty healthy women. ([Clinical, Cosmetic and Investigational Dermatology, 2017](https://pubmed.ncbi.nlm.nih.gov/28860834/))
- Cryotherapy with liquid nitrogen achieved a higher cure rate (39%) than salicylic acid (24%) and a wait-and-see approach (16%) for cutaneous warts at 13 weeks in primary care patients. ([CMAJ, 2010](https://pubmed.ncbi.nlm.nih.gov/20837684/))
- A moisturizer containing licochalcone A, 1,2-decanediol, L-carnitine, and salicylic acid significantly reduced noninflammatory, inflammatory, and total acne lesion counts compared to a vehicle control in Thai patients during a 12-week maintenance phase. ([BioMed Research International, 2020](https://pubmed.ncbi.nlm.nih.gov/33150170/))
- Treatment with 2% supramolecular salicylic acid hydrogel resulted in a regression and markedly improvement rate of 51.01% compared to 43.10% for Adapaline gel in patients with mild to moderate facial acne vulgaris, showing no significant difference in efficacy. ([Journal of Cosmetic Dermatology, 2024](https://pubmed.ncbi.nlm.nih.gov/38590107/))
- Repeated short-contact 70% glycolic acid peels provided superior results in atrophic acne scars compared to daily low-strength glycolic acid cream or placebo in 58 women over 24 weeks. ([International Journal of Dermatology, 2000](https://pubmed.ncbi.nlm.nih.gov/11095203/))
- Serial glycolic acid peels combined with a modified Kligman formula significantly reduced facial PIH severity in Indian patients compared to the modified Kligman formula alone. ([Dermatologic Surgery, 2017](https://pubmed.ncbi.nlm.nih.gov/28114204/))
- A dermocosmetic cream containing Punica granatum Pericarp extract, Salicylic acid, Niacinamide, Zinc gluconate, and Aqua Posae Filiformis significantly decreased inflammatory, non-inflammatory, and total lesion counts in subjects with mild to moderate acne compared to untreated hemi-faces after 15 days. ([Journal of Cosmetic Dermatology, 2026](https://pubmed.ncbi.nlm.nih.gov/41487026/))
- Daily use of a deep cleansing gel containing salicylic acid 2%, zinc gluconate 0.2% and lipohydroxy acid 0.05% significantly reduced total lesion count by 56.3% after 84 days in 35 subjects with mild to moderate truncal acne. ([Clinical, Cosmetic and Investigational Dermatology, 2023](https://pubmed.ncbi.nlm.nih.gov/36698447/))
- Different strains of Propionibacterium acnes modulate cutaneous innate immunity with varying pro-inflammatory potentials, with P. acnes type III showing the highest and P. avidum the weakest, and zinc gluconate down-regulates the expression of most induced immune markers. ([Experimental Dermatology, 2013](https://pubmed.ncbi.nlm.nih.gov/23947673/))
- Silybum marianum flower extract increased human hair follicle dermal papilla cell proliferation and VEGF production while suppressing cellular senescence, and in a clinical study using hair shampoo, it significantly increased hair density and total hair count at 16 and 24 weeks compared with a placebo group. ([Journal of Cosmetic Dermatology, 2024](https://pubmed.ncbi.nlm.nih.gov/37675655/))
- Topical 0.5% silymarin-loaded antioxidant serum applied twice daily significantly reduced clinical acne severity, lesion counts, and melanin pigmentation in 22 Korean acne patients over 4 weeks without associated adverse events. ([Journal of Cosmetic Dermatology, 2023](https://pubmed.ncbi.nlm.nih.gov/36204969/))
- Topical silymarin cream 1.4% showed comparable results to salicylic acid 30% peels in reducing acne severity in 30 patients with mild to moderate acne vulgaris. ([Journal of Cutaneous Medicine and Surgery, 2024](https://pubmed.ncbi.nlm.nih.gov/37942562/))
- Topical treatment with pumpkin seed oil healed uniform wounds in rats, achieving full re-epithelialization, reappearance of skin appendages, and well-organized collagen fibers compared to untreated controls. ([Lipids in Health and Disease, 2016](https://pubmed.ncbi.nlm.nih.gov/27068642/))
- A combinational sunscreen formulation of UV filters, melatonin, and pumpkin seed oil ameliorated UV radiation-induced photoaging in adult Wistar albino rats by increasing SOD, GSH-Px, CAT, and collagen levels, while decreasing skin edema, skin thickness, and inflammatory cytokines compared to UV-exposed controls. ([European Journal of Pharmaceutical Sciences, 2019](https://pubmed.ncbi.nlm.nih.gov/30414837/))
- Topical pumpkin seed oil increased hair follicle proliferation in mice without causing liver toxicity, oxidative stress, or genotoxicity. ([Acta Histochemica, 2022](https://pubmed.ncbi.nlm.nih.gov/35447441/))

## What reviewers say

This treatment is frequently praised for its effectiveness on oily, blemish-prone, and sensitive skin, particularly in managing blackheads and closed comedones, with many users reporting clearer skin and fewer breakouts. A significant number of users also appreciate its lightweight texture and matte finish. Some users note a strong chemical scent and a drying effect, with a few experiencing irritation or a sticky consistency.

- Liked: Reduces blemishes (mostly mentioned)
- Liked: Lightweight texture (often mentioned)
- Disliked: Strong chemical scent (often mentioned)
- Liked: Matte finish (sometimes noted)
- Liked: Prevents recurrence (sometimes noted)
- Disliked: Drying effect (sometimes noted)
- Disliked: Can cause irritation (rarely noted)
- Disliked: Sticky consistency (rarely noted)

## How to apply

- Use this PM routine for your evening skincare. Start using the serum 3 times a week and increase to daily use if your skin feels comfortable.
- Apply the serum after cleansing and toner, but right before your moisturizer. This step locks in deep hydration for dry skin.
- Gently press 2-3 drops of the serum into your skin using your palms. Let it absorb completely for a minute ⏱ before applying your next product.
- Since your skin is sensitive, apply the serum on completely dry skin for better tolerance and less irritation.
- Avoid the sensitive eye area during application. Always do a patch test before your first use to ensure your skin reacts well.
- Video: https://storage.pora.ai/c879dda8655a61c19d3d8c9ebad6b06d.mp4

## Questions and answers

### Why does Lovi advise caution with Avene Cleanance Comedomed for dry sensitive skin?

Lovi advises caution because this treatment offers moderate exfoliation from salicylic acid and glycolic acid, which may cause dryness and irritation on dry sensitive skin. A product for this skin needs effective moisturizing ingredients and barrier support components that provide excellent hydration and texture improvement without any risk of irritation.

### Which ingredients make this treatment a poor fit for dry sensitive skin?

Salicylic acid and glycolic acid make this treatment a poor fit because they offer moderate exfoliation that may cause dryness and irritation on dry sensitive skin. A treatment for this skin needs nourishing and moisturizing ingredients that provide deep hydration and skin barrier support without any risk of irritation.

### What does Salicylic Acid do for dry sensitive skin?

Salicylic acid is generally a poor fit for dry, sensitive skin because it is designed to clear out pores by removing excess oil, which can easily leave dry skin irritated. A product of this type needs gentle exfoliating helpers paired with rich, soothing moisturizers and barrier-repairing ingredients to keep dry skin calm and comfortable.

### What does Glycolic Acid do for dry sensitive skin?

Glycolic acid can be too harsh for dry sensitive skin and may cause irritation, so this skin type needs gentle calming ingredients and deeply nourishing moisturizers to keep the skin barrier safe and smooth.
Sources: [Acta Dermato-venereologica, 1995](https://pubmed.ncbi.nlm.nih.gov/8651024/), [The British Journal of Dermatology, 1997](https://pubmed.ncbi.nlm.nih.gov/9470910/)

### Where does this treatment go in a skincare routine for dry sensitive skin?

This treatment goes in the evening routine for dry sensitive skin, starting just once a week. Because it contains exfoliating acids like salicylic acid and glycolic acid, it may cause dryness and irritation on this skin type. A product for this skin needs gentle exfoliating ingredients paired with rich hydrating and nourishing ingredients to keep it soft and smooth.

### Can I use this treatment with retinol, and in what order?

Using this treatment with retinol may cause extra dryness and irritation on your dry and sensitive skin. It is best to avoid using them together, or alternate them on different nights to keep your skin calm and comfortable.

### How often should I use this treatment?

This treatment is a poor fit for your dry and sensitive skin, as its exfoliating acids can cause extra dryness and irritation. If you choose to use it, start just once a week in the evening to test your skin tolerance, and this type of skin needs a product that provides gentle hydration and barrier-repairing ingredients instead.

### Can this treatment clog pores, cause breakouts or purging for dry sensitive skin?

This treatment is unlikely to clog pores, but the exfoliating acids may cause dryness and irritation on dry sensitive skin. A product for this skin needs gentle hydrating ingredients like glycerin to keep it soft and calm without flaking.

### Is this treatment fragrance-free and alcohol-free?

It has no drying alcohol and contains fragrance (parfum). Cetearyl alcohol is a fatty alcohol, which soften the skin.

## Alternatives for dry sensitive skin

- [SkinCeuticals C E Ferulic](https://lovi.care/skincare/ae/p/skinceuticals/c-e-ferulic/for/dry-sensitive-skin) — Superior fit — AED 715.99 at Amazon
- [Paula's Choice RESIST Super Antioxidant Concentrate Serum](https://lovi.care/skincare/ae/p/paula-s-choice/resist-super-antioxidant-concentrate-serum/for/dry-sensitive-skin) — Superior fit — AED 347.75 at Amazon
- [Augustinus Bader The Serum](https://lovi.care/skincare/ae/p/augustinus-bader/the-serum/for/dry-sensitive-skin) — Superior fit — AED 1,348.00 at Amazon

## Routine for dry sensitive skin

### AM

- Cleanser: [CeraVe Hydrating Cleanser](https://lovi.care/skincare/ae/p/cerave/hydrating-facial-cleanser/for/dry-sensitive-skin) — Superior fit — AED 32.95 at Amazon
- Soothing Toner: [Clarins Toning Lotion with Camomile](https://lovi.care/skincare/ae/p/clarins/soothing-toning-lotion/for/dry-sensitive-skin) — Superior fit — AED 81.41 at Amazon
- Moisturizer with Sun Protection: [Dr.G Green Mild Up Sun+](https://lovi.care/skincare/ae/p/dr-g/green-mild-up-sun/for/dry-sensitive-skin) — Superior fit — AED 81.00 at Amazon

### PM

- Pre-Cleanser: [MISSHA Ultra Hyalon Cleansing Cream](https://lovi.care/skincare/ae/p/missha/ultra-hyalon-cleansing-cream/for/dry-sensitive-skin) — Superior fit — AED 35.29 at Amazon
- Cleanser: [CeraVe Hydrating Cleanser](https://lovi.care/skincare/ae/p/cerave/hydrating-facial-cleanser/for/dry-sensitive-skin) — Superior fit — AED 32.95 at Amazon
- Soothing Toner: [Clarins Toning Lotion with Camomile](https://lovi.care/skincare/ae/p/clarins/soothing-toning-lotion/for/dry-sensitive-skin) — Superior fit — AED 81.41 at Amazon
- Serum or Treatment: [Peach & Lily Glass Skin Refining Serum](https://lovi.care/skincare/ae/p/peach-and-lily/glass-skin-refining-serum/for/dry-sensitive-skin) — Superior fit — AED 168.76 at Amazon
- Moisturizer: [Elizabeth Arden Ceramide Lift and Firm Night Cream](https://lovi.care/skincare/ae/p/elizabeth-arden/advanced-ceramide-lift-and-firm-night-cream/for/dry-sensitive-skin) — Superior fit — AED 493.00 at Amazon

### Weekly

- Pre-Cleanser: [MISSHA Ultra Hyalon Cleansing Cream](https://lovi.care/skincare/ae/p/missha/ultra-hyalon-cleansing-cream/for/dry-sensitive-skin) — Superior fit — AED 35.29 at Amazon
- Cleanser: [CeraVe Hydrating Cleanser](https://lovi.care/skincare/ae/p/cerave/hydrating-facial-cleanser/for/dry-sensitive-skin) — Superior fit — AED 32.95 at Amazon
- Enzyme Powder: [Fancl Facial Washing Powder](https://lovi.care/skincare/ae/p/fancl/facial-washing-powder/for/dry-sensitive-skin) — Superior fit — AED 91.68 at Amazon
- Nourishing Mask: [Pyunkang Yul Calming Mask Pack](https://lovi.care/skincare/ae/p/pyunkang-yul/calming-mask-pack/for/dry-sensitive-skin) — Superior fit — AED 122.85 at Amazon
- Serum or Treatment: [Peach & Lily Glass Skin Refining Serum](https://lovi.care/skincare/ae/p/peach-and-lily/glass-skin-refining-serum/for/dry-sensitive-skin) — Superior fit — AED 168.76 at Amazon
- Moisturizer: [Elizabeth Arden Ceramide Lift and Firm Night Cream](https://lovi.care/skincare/ae/p/elizabeth-arden/advanced-ceramide-lift-and-firm-night-cream/for/dry-sensitive-skin) — Superior fit — AED 493.00 at Amazon

## Where to buy

No store in United Arab Emirates has a checked price for this product, so the page shows none.

## Ingredients

Water, Propanediol, Proylene Glycol, Glycerin, Cetearyl Alcohol, Cetearyl Glucoside, Glyceryl Stearate, Peg-100 Stearate, Silica, Dimethicone, Bht, Caprylic Capric Triglyceride, Pumpkin Seed Oil, Sodium Hydroxide, Sodium Polyacrylate, Sodium Stearoyl Glutamate, Zinc Gluconate, Capryloyl Glycine, Citric Acid, Parfum, Disodium Edta, Sodium Benzoate, Potassium Sorbate, Glyceryl Laurate, Monolaurin, Silybum Marianum Fruit Extract, Butylene Glycol, Silymarin, Dipotassium Glycyrrhizate, Tocopherol, Glycolic Acid, Salicylic Acid, Xanthan Gum
## About the Lovi Fit

Lovi: Unbiased, science-based skincare AI trained on real user outcomes.

Lovi calculates every fit score from the full ingredient list with brand-independent rules its dermatologists and cosmetic chemists build and review, and personalizes every pick with AI trained on the real results of millions of users. Lovi trains its fit score models on a proprietary dataset built from more than 10,000 expert-labeled products and more than 100,000 simulated examples, following an internally consistent methodology presented at Cosmoprof, AMWC, and Skin of Color Update. Levels from best to worst: Superior, High, Average, Low, Caution, Warning.

Behind this fit score: Nadia Kapleva, MS (Co-founder, Medical Director); Alexey Shagraev, PhD (Co-founder, CEO and CTO); Dr. Sofía Perea Pérez, MD, MSc (Medical Board); Aishani Shah, MD (Medical Board); Asya Zubkova, MS (Medical Board); Hanna Kurets, MD (Medical Board, Medical Advisor); Elina Nazarenko, MD (Medical Board); Victoria Derkova, MS (Medical Board).

Page built Nov 8, 2026.

More from Lovi: https://lovi.care/skincare/llms.txt

## This page in other countries

- United States: https://lovi.care/skincare/p/avene/cleanance-comedomed/for/dry-sensitive-skin
- United Kingdom: https://lovi.care/skincare/uk/p/avene/cleanance-comedomed/for/dry-sensitive-skin
- Ireland: https://lovi.care/skincare/ie/p/avene/cleanance-comedomed/for/dry-sensitive-skin
- Germany: https://lovi.care/skincare/de/p/avene/cleanance-comedomed/for/dry-sensitive-skin
- France: https://lovi.care/skincare/fr/p/avene/cleanance-comedomed/for/dry-sensitive-skin
- Italy: https://lovi.care/skincare/it/p/avene/cleanance-comedomed/for/dry-sensitive-skin
- Netherlands: https://lovi.care/skincare/nl/p/avene/cleanance-comedomed/for/dry-sensitive-skin
- Spain: https://lovi.care/skincare/es/p/avene/cleanance-comedomed/for/dry-sensitive-skin
- Canada: https://lovi.care/skincare/ca/p/avene/cleanance-comedomed/for/dry-sensitive-skin
- Australia: https://lovi.care/skincare/au/p/avene/cleanance-comedomed/for/dry-sensitive-skin
- Singapore: https://lovi.care/skincare/sg/p/avene/cleanance-comedomed/for/dry-sensitive-skin
- Saudi Arabia: https://lovi.care/skincare/sa/p/avene/cleanance-comedomed/for/dry-sensitive-skin
- United Arab Emirates: https://lovi.care/skincare/ae/p/avene/cleanance-comedomed/for/dry-sensitive-skin (this page)