# 111SKIN Y Theorem Repair Light Serum NAC Y2 for oily acne-prone skin

**Lovi Fit: Average fit for oily acne-prone skin.**
Oily Skin Fit: High · Effectiveness: Average · Safety: High.

Page: https://lovi.care/skincare/ae/p/111skin/y-theorem-repair-light-serum-nac-y2/for/oily-acne-prone-skin

The Lovi Fit is the same in every country; only the stores and prices differ, and the ones here are for the United Arab Emirates.

Brand: [111SKIN](https://lovi.care/skincare/ae/brands/111skin)
Category: [Serums and treatments](https://lovi.care/skincare/ae/best/serums)

This fit is calculated for the concerns frequently associated with oily acne-prone skin: shine, breakouts, blemishes, and enlarged pores. For scores based on a full skin profile (12D face scan, goals, preferences), use the Lovi app.

Works for oily acne-prone skin; other serums fit it better.

## Why this fit

- Offers moderate benefits for your oily skin, as niacinamide and sodium ascorbyl phosphate help regulate oil and provide antioxidant protection, though ingredients like Glycerin and Aloe Barbadensis Extract offer general hydration rather than targeted treatment for your acne and blemishes.
- The presence of acetyl cysteine and niacinamide aids in skin repair and barrier resilience, contributing to overall skin health.
- The formula is safe for your oily skin, with no reported risks of irritation due to the absence of harsh or prohibited ingredients.

## Fit by skin type

- [Oily skin](https://lovi.care/skincare/ae/p/111skin/y-theorem-repair-light-serum-nac-y2/for/oily-skin): Average
- [Dry skin](https://lovi.care/skincare/ae/p/111skin/y-theorem-repair-light-serum-nac-y2/for/dry-skin): Average
- [Combination skin](https://lovi.care/skincare/ae/p/111skin/y-theorem-repair-light-serum-nac-y2/for/combination-skin): Average
- [Sensitive skin](https://lovi.care/skincare/ae/p/111skin/y-theorem-repair-light-serum-nac-y2/for/sensitive-skin): Average
- [Acne-prone skin](https://lovi.care/skincare/ae/p/111skin/y-theorem-repair-light-serum-nac-y2/for/acne-prone-skin): Average
- [Skin with dark spots](https://lovi.care/skincare/ae/p/111skin/y-theorem-repair-light-serum-nac-y2/for/dark-spots): Average
- [Mature skin](https://lovi.care/skincare/ae/p/111skin/y-theorem-repair-light-serum-nac-y2/for/mature-skin): Average
- [Dry sensitive skin](https://lovi.care/skincare/ae/p/111skin/y-theorem-repair-light-serum-nac-y2/for/dry-sensitive-skin): Average
- [Oily acne-prone skin](https://lovi.care/skincare/ae/p/111skin/y-theorem-repair-light-serum-nac-y2/for/oily-acne-prone-skin): Average (this page)

## Key ingredients

Nac Y2, Niacinamide, Calendula Officinalis Extract, Aloe Barbadensis Extract, Acetyl Cysteine

## What the research says

- Combined ascorbyl palmitate and sodium ascorbyl phosphate treatment significantly reduced facial sebum secretions in healthy female volunteers compared to a placebo control over 90 days. ([Drug Research, 2017](https://pubmed.ncbi.nlm.nih.gov/27756097/))
- A single application of a moisturizing fluid containing hyaluronic acid 1%, glycerin 5%, and Centella asiatica stem cells extract significantly increased skin hydration by 29% and reduced transepidermal water loss at 24 hours compared to baseline and an untreated control site in twenty healthy women. ([Clinical, Cosmetic and Investigational Dermatology, 2017](https://pubmed.ncbi.nlm.nih.gov/28860834/))
- Topical genistein and N-acetyl cysteine prevent ultraviolet-induced photoaging signaling pathways in human skin in vivo by inhibiting specific kinase activities and antioxidant mechanisms without acting as sunscreens. ([The Journal of Investigative Dermatology, 2003](https://pubmed.ncbi.nlm.nih.gov/12713590/))
- Glutathione amino acid precursors effectively increase cellular glutathione levels, reducing oxidative stress, ATP depletion, and DNA damage in human keratinocytes, clinical subjects, and ex vivo skin compared to controls. ([Journal of the European Academy of Dermatology and Venereology, 2024](https://pubmed.ncbi.nlm.nih.gov/38189670/))
- Topical glutathione improves hyperpigmentation, reduces ultraviolet-induced erythema and wrinkles, decreases transepidermal water loss, and enhances antioxidant capacity. ([The Journal of Clinical and Aesthetic Dermatology, 2025](https://pubmed.ncbi.nlm.nih.gov/41416233/))
- RayGel reduced skin reaction severity with a lower average score of 93.7 compared to 123.3 for the placebo group in patients undergoing whole breast external-beam irradiation. ([American Journal of Surgery, 2005](https://pubmed.ncbi.nlm.nih.gov/15862509/))
- Topical post-laser application of human adipocyte-derived mesenchymal stem cell media combined with niacinamide significantly improved wrinkle index, melanin index, patient satisfaction, and investigator esthetic improvement scores compared to vehicle cream in patients with aging skin. ([Journal of Cosmetic Dermatology, 2021](https://pubmed.ncbi.nlm.nih.gov/33103316/))
- Topical nicotinamide prevented solar-simulated UV-induced immunosuppression in healthy volunteers, and men experienced immunosuppression at solar-simulated UV doses three times lower than those required for women. ([The Journal of Investigative Dermatology, 2008](https://pubmed.ncbi.nlm.nih.gov/17882270/))
- Topical 5% niacinamide applied twice daily for 12 weeks reduced fine lines and wrinkles, hyperpigmented spots, red blotchiness, and skin sallowness, and improved skin elasticity compared to vehicle control in 50 female white subjects with facial photoaging. ([Dermatologic Surgery, 2005](https://pubmed.ncbi.nlm.nih.gov/16029679/))
- Topical application of Calendula officinalis extract cream significantly improved skin hydration and firmness (reflected in significant changes in R0 and R6 parameters) in 21 healthy human volunteers compared to a base cream. ([Acta Poloniae Pharmaceutica, 2011](https://pubmed.ncbi.nlm.nih.gov/21928714/))
- Treatment with standardized extract of Calendula officinalis L. led to a shorter epithelization time and faster healing speed compared to mineral oil in patients with acute skin loss wounds of the hand and fingers healing by secondary intention. ([Tissue Barriers, 2022](https://pubmed.ncbi.nlm.nih.gov/34674610/))
- Topical administration of Calendula provides weak evidence of effectiveness in acute and chronic wounds compared to standard treatments based on a narrative review of available trials. ([Wounds, 2008](https://pubmed.ncbi.nlm.nih.gov/25941793/))
- A cream combining propolis, tea tree oil, and Aloe vera reduced erythema scars, acne severity index, and total lesion count better than erythromycin cream in sixty patients with mild to moderate acne vulgaris compared to placebo. ([Clinical Pharmacology, 2018](https://pubmed.ncbi.nlm.nih.gov/30588129/))
- Topical aloe vera gel significantly accelerated split-thickness skin graft donor-site healing compared to placebo in 12 patients, but showed no significant difference in pain relief. ([Plastic and Reconstructive Surgery, 2018](https://pubmed.ncbi.nlm.nih.gov/29649056/))
- Topical application of Aloe vera cream reduced postoperative pain at rest and during defecation, accelerated wound healing at two weeks, and decreased analgesic requirements in patients after open hemorrhoidectomy compared to placebo. ([Journal of Alternative and Complementary Medicine, 2010](https://pubmed.ncbi.nlm.nih.gov/20569031/))
- Topical N-acetylcysteine plus doxycycline achieved significantly greater improvements in total lesion count, inflammatory lesion count, IGA, GAGS, and CADI scores compared to benzoyl peroxide plus doxycycline in 40 patients with moderate acne vulgaris. ([Dermatology Practical & Conceptual, 2026](https://pubmed.ncbi.nlm.nih.gov/42190184/))
- Topical application of alpha-tocopherol, l-ascorbic acid, alpha-lipoic acid, glutathione ethylester, and N-acetylcysteine decreased UVB-radiation-induced cell death, apoptosis, and lipid peroxidation in ex vivo pig skin explants compared to untreated controls. ([Radiation Research, 2003](https://pubmed.ncbi.nlm.nih.gov/12537526/))
- Topical vitamin C, vitamin E, and acetylcysteine showed similar effects on the healing of experimentally created corneal wounds in rabbits, with no statistically significant differences compared to each other. ([Indian Journal of Ophthalmology, 2020](https://pubmed.ncbi.nlm.nih.gov/33229673/))

## Why other serums fit oily acne-prone skin better

- A cream combining propolis, tea tree oil, and Aloe vera reduced erythema scars, acne severity index, and total lesion count better than erythromycin cream in sixty patients with mild to moderate acne vulgaris compared to placebo. ([Clinical Pharmacology, 2018](https://pubmed.ncbi.nlm.nih.gov/30588129/))
- Niacinamide and ferulic acid incorporated in a stable multiple emulsion successfully reduced melanin, sebum, and skin erythema while improving skin elasticity and hydration in human skin compared to a placebo. ([BioMed Research International, 2022](https://pubmed.ncbi.nlm.nih.gov/35342760/))

## What reviewers say

Users with oily, combination, or humid-climate skin praise the serum's lightweight, water-like texture for providing deep hydration without greasiness, often noting significant improvements in redness, inflammation, and post-procedure healing. A notable portion of reviewers feel the extremely high price point is unjustified, citing strong fragrance and a lack of dramatic anti-aging results as key drawbacks compared to more affordable alternatives.

- Liked: Lightweight & fast-absorbing (mostly mentioned)
- Disliked: Extremely expensive (mostly mentioned)
- Liked: Hydrating & plumping (often mentioned)
- Liked: Soothing & healing (often mentioned)
- Liked: Good for oily skin (sometimes noted)
- Disliked: Lack of visible results (sometimes noted)
- Disliked: Strong fragrance (sometimes noted)
- Disliked: Potential irritation (rarely noted)

## How to apply

- Could be used as part of your PM routine. Start 3 times a week and build up to daily use if your skin tolerates it well.
- Apply your serum after cleansing and toning, but before putting on your moisturizer.
- Gently press 2 to 3 drops of the serum into your skin and let it absorb for a minute.
- Apply the serum on clean, dry skin to help manage your blemishes safely.
- Do a patch test before your first use and avoid the delicate eye area.
- Video: https://storage.pora.ai/c879dda8655a61c19d3d8c9ebad6b06d.mp4

## Questions and answers

### How well does 111SKIN Y Theorem Repair Light Serum work for oily acne-prone skin?

This serum works moderately well for your oily acne-prone skin, as niacinamide and sodium ascorbyl phosphate help control oil while other ingredients offer general hydration instead of targeted blemish treatment. It is safe and unlikely to cause irritation, but a treatment of this type needs ingredients like propolis, vitamin C, and specialized extracts that directly target acne and uneven texture.
Sources: [Drug Research, 2017](https://pubmed.ncbi.nlm.nih.gov/27756097/)

### Which ingredients make this serum a good fit for oily acne-prone skin?

Niacinamide, sodium ascorbyl phosphate, and acetyl cysteine make this serum a good fit by helping regulate oil, providing antioxidants, and aiding skin repair. A treatment for this skin needs ingredients like niacinamide, propolis, or Vitamin C, along with soothing extracts and lightweight hydrators to target blemishes and control oil without breakouts.
Sources: [Drug Research, 2017](https://pubmed.ncbi.nlm.nih.gov/27756097/)

### What does Nac Y2 do for oily acne-prone skin?

NAC Y2 helps calm stressed, oily skin and supports a clearer, more balanced look. It is unlikely to feel heavy, but oily skin with breakouts also needs ingredients that clear pores and control shine.

### What does Niacinamide do for oily acne-prone skin?

Niacinamide helps balance oil production, calms redness, and is unlikely to irritate oily, acne-prone skin while improving blemishes. Clinical tests show it reduces excess oil and helps clear up both inflammatory and non-inflammatory acne breakouts.
Sources: [Journal of Cosmetic and Laser Therapy, 2006](https://pubmed.ncbi.nlm.nih.gov/16766489/), [Journal of Cosmetic Dermatology, 2024](https://pubmed.ncbi.nlm.nih.gov/38299457/)

### Where does this serum go in a skincare routine for oily acne-prone skin?

This treatment goes in the evening routine after cleansing and before your moisturizer. It is safe for your oily skin and unlikely to cause irritation, though oily acne-prone skin also needs targeted blemish-fighting ingredients and oil-regulating actives to see the best results.

### Can I use this serum with retinol, and in what order?

You can use this serum with retinol by applying it during your evening routine after cleansing and toning, and before your moisturizer. It is unlikely to cause irritation on oily skin, but this skin type also needs targeted acne-fighting ingredients like salicylic acid or benzoyl peroxide to properly clear breakouts.
Sources: [Journal of Cosmetic Dermatology, 2024](https://pubmed.ncbi.nlm.nih.gov/38102855/)

### How often should I use this serum?

You can use this serum in your evening routine, as treatments fit well there for simplicity and extra safety around sun exposure. It is safe for your oily skin with no reported risks of irritation, though an oily acne-prone skin needs products with targeted blemish-fighting ingredients and oil-balancing actives for the best results.

### Can this serum clog pores, cause breakouts or purging for oily acne-prone skin?

This serum is unlikely to cause breakouts or clog pores on oily acne-prone skin because it has a safe profile with no harsh ingredients. However, it offers only moderate benefits for your breakouts, as an oily acne-prone skin type needs targeted blemish-fighting ingredients and oil-balancing components rather than general hydration.

### Is this serum fragrance-free and alcohol-free?

It contains fragrance (benzyl alcohol and parfum) and drying alcohol (alcohol).

## Alternatives for oily acne-prone skin

- [Clinique Fresh Pressed Daily Booster with Pure Vitamin C 10%](https://lovi.care/skincare/ae/p/clinique/fresh-pressed-daily-booster-with-pure-vitamin-c-10/for/oily-acne-prone-skin) — Superior fit — AED 365.22 at Amazon
- [Neogen Dermalogy Real Vitamin C Serum](https://lovi.care/skincare/ae/p/neogen-dermalogy/real-vitamin-c-serum/for/oily-acne-prone-skin) — Superior fit — AED 89.30 at Amazon
- [NEOGEN DERMALOGY REAL VITA C SERUM](https://lovi.care/skincare/ae/p/neogen-dermalogy/real-vita-c-serum/for/oily-acne-prone-skin) — High fit — AED 89.30 at Amazon

## Pairs well with

- Cleanser: [IS Clinical Cleansing Complex](https://lovi.care/skincare/ae/p/is-clinical/cleansing-complex/for/oily-acne-prone-skin) — Superior fit — AED 138.20 at Amazon
- Hydrating Toner: [Paula's Choice Pore-Reducing Toner](https://lovi.care/skincare/ae/p/paula-s-choice/skin-balancing-pore-reducing-toner/for/oily-acne-prone-skin) — Superior fit — AED 145.00 at Amazon
- Moisturizer: [COSRX Oil-Free Ultra-Moisturizing Lotion with Birch Sap](https://lovi.care/skincare/ae/p/cosrx/oil-free-ultra-moisturizing-lotion-with-birch-sap/for/oily-acne-prone-skin) — Superior fit — AED 33.40 at Amazon

## Where to buy

- Amazon.ae: AED 717.18 (https://www.amazon.ae/dp/B019FCU3IW?tag=lovi00-21&linkCode=osi&th=1&psc=1)
- Lookfantastic: AED 1,188.00 (https://www.lookfantastic.ae/p/111skin-y-theorem-repair-light-serum-nac-y2-30ml/11118362/)
Prices checked 15 Oct – 4 Nov 2026.

## Ingredients

Water, Glycerin, Alcohol, Benzyl Alcohol, Aloe Barbadensis Extract, Calendula Officinalis Extract, Carbomer, Sodium Hydroxide, Aesculus Hippocastanum Extract, Sodium Ascorbyl Phosphate, Panthenol, Niacinamide, Thiamin, Riboflavin, Pyridoxine, Cyanocobalamin, Glycyrrhiza Glabra Root Extract Licorice Root Extract, Prunus Armeniaca Kernel Oil Apricot Kernel Oil, Acetyl Cysteine, Parfum
## About the Lovi Fit

Lovi: Unbiased, science-based skincare AI trained on real user outcomes.

Lovi calculates every fit score from the full ingredient list with brand-independent rules its dermatologists and cosmetic chemists build and review, and personalizes every pick with AI trained on the real results of millions of users. Lovi trains its fit score models on a proprietary dataset built from more than 10,000 expert-labeled products and more than 100,000 simulated examples, following an internally consistent methodology presented at Cosmoprof, AMWC, and Skin of Color Update. Levels from best to worst: Superior, High, Average, Low, Caution, Warning.

Behind this fit score: Nadia Kapleva, MS (Co-founder, Medical Director); Alexey Shagraev, PhD (Co-founder, CEO and CTO); Dr. Sofía Perea Pérez, MD, MSc (Medical Board); Aishani Shah, MD (Medical Board); Asya Zubkova, MS (Medical Board); Hanna Kurets, MD (Medical Board, Medical Advisor); Elina Nazarenko, MD (Medical Board); Victoria Derkova, MS (Medical Board).

Page built Nov 8, 2026.

More from Lovi: https://lovi.care/skincare/llms.txt

## This page in other countries

- United States: https://lovi.care/skincare/p/111skin/y-theorem-repair-light-serum-nac-y2/for/oily-acne-prone-skin
- United Kingdom: https://lovi.care/skincare/uk/p/111skin/y-theorem-repair-light-serum-nac-y2/for/oily-acne-prone-skin
- Ireland: https://lovi.care/skincare/ie/p/111skin/y-theorem-repair-light-serum-nac-y2/for/oily-acne-prone-skin
- Germany: https://lovi.care/skincare/de/p/111skin/y-theorem-repair-light-serum-nac-y2/for/oily-acne-prone-skin
- France: https://lovi.care/skincare/fr/p/111skin/y-theorem-repair-light-serum-nac-y2/for/oily-acne-prone-skin
- Italy: https://lovi.care/skincare/it/p/111skin/y-theorem-repair-light-serum-nac-y2/for/oily-acne-prone-skin
- Netherlands: https://lovi.care/skincare/nl/p/111skin/y-theorem-repair-light-serum-nac-y2/for/oily-acne-prone-skin
- Spain: https://lovi.care/skincare/es/p/111skin/y-theorem-repair-light-serum-nac-y2/for/oily-acne-prone-skin
- Canada: https://lovi.care/skincare/ca/p/111skin/y-theorem-repair-light-serum-nac-y2/for/oily-acne-prone-skin
- Australia: https://lovi.care/skincare/au/p/111skin/y-theorem-repair-light-serum-nac-y2/for/oily-acne-prone-skin
- Singapore: https://lovi.care/skincare/sg/p/111skin/y-theorem-repair-light-serum-nac-y2/for/oily-acne-prone-skin
- Saudi Arabia: https://lovi.care/skincare/sa/p/111skin/y-theorem-repair-light-serum-nac-y2/for/oily-acne-prone-skin
- United Arab Emirates: https://lovi.care/skincare/ae/p/111skin/y-theorem-repair-light-serum-nac-y2/for/oily-acne-prone-skin (this page)