# Tretinoin and collagen peptide Page: https://lovi.care/skincare/ae/ingredients/tretinoin-and-collagen-peptide The Lovi Fit is the same in every country; only the stores and prices differ, and the ones here are for the United Arab Emirates. Keep them apart Use them at different times of day, applying [collagen peptides](https://lovi.care/skincare/ae/ingredients/collagen-peptide) in the morning and [tretinoin](https://lovi.care/skincare/ae/ingredients/tretinoin) at night. Using them together can cause extra skin irritation because both ingredients work hard at the same time. The shopper can change their routine by using a gentler strength or more time between the two products. - [All about tretinoin](https://lovi.care/skincare/ae/ingredients/tretinoin) - [All about collagen peptide](https://lovi.care/skincare/ae/ingredients/collagen-peptide) ### [Tretinoin](https://lovi.care/skincare/ae/ingredients/tretinoin) products - [Retin-A Cream](https://lovi.care/skincare/ae/p/retin-a/cream/for/oily-skin) — High fit - [Tri-Luma Cream](https://lovi.care/skincare/ae/p/tri-luma/cream/for/dark-spots) — Average fit — [AED 81.95 at Amazon](https://www.amazon.ae/dp/B0B369DBWZ?tag=lovi00-21&linkCode=osi&th=1&psc=1) - [Musely The Spot Cream](https://lovi.care/skincare/ae/p/musely/the-spot-cream/for/mature-skin) — High fit - [Obagi Tretinoin Cream 0.05%](https://lovi.care/skincare/ae/p/obagi/tretinoin-cream-0-05/for/oily-skin) — High fit - [Taro Tretinoin Cream](https://lovi.care/skincare/ae/p/taro/tretinoin-cream/for/combination-skin) — High fit - [Mylan Tretinoin](https://lovi.care/skincare/ae/p/mylan/tretinoin/for/acne-prone-skin) — Average fit - [Curology Formula](https://lovi.care/skincare/ae/p/curology/formula/for/oily-skin) — High fit - [Menarini A-Ret Gel](https://lovi.care/skincare/ae/p/menarini/a-ret-gel/for/oily-skin) — High fit ### [Collagen peptide](https://lovi.care/skincare/ae/ingredients/collagen-peptide) products - [SkinMedica TNS Advanced+ Serum](https://lovi.care/skincare/ae/p/skinmedica/tns-advanced-serum/for/mature-skin) — High fit — [AED 1,099.99 at Amazon](https://www.amazon.ae/dp/B07SCJ445R?tag=lovi00-21&linkCode=osi&th=1&psc=1) - [Hero Mighty Patch](https://lovi.care/skincare/ae/p/hero/mighty-patch/for/sensitive-skin) — High fit - [The INKEY List Collagen Peptide Serum](https://lovi.care/skincare/ae/p/the-inkey-list/collagen-peptide-serum/for/dry-sensitive-skin) — High fit - [Olay Regenerist Collagen Peptide 24 Serum](https://lovi.care/skincare/ae/p/olay-regenerist/collagen-peptide-24-serum/for/dry-skin) — High fit - [No7 Pure Retinol 1% Night Concentrate](https://lovi.care/skincare/ae/p/no7/pure-retinol-1-night-concentrate/for/combination-skin) — High fit - [No7 Protect & Perfect Intense Advanced Night Cream](https://lovi.care/skincare/ae/p/no7/protect-and-perfect-intense-advanced-night-cream/for/mature-skin) — Superior fit — [AED 77.00 at Amazon](https://www.amazon.ae/dp/B09NQCNPJT?tag=lovi00-21&linkCode=osi&th=1&psc=1) - [Olay Regenerist Collagen Peptide 24 MAX Face Moisturizer](https://lovi.care/skincare/ae/p/olay/regenerist-collagen-peptide-24-max-face-moisturizer/for/dry-skin) — High fit — [AED 158.28 at Amazon](https://www.amazon.ae/dp/B09HN5NXVR?tag=lovi00-21&linkCode=osi&th=1&psc=1) - [No.7 Pure Retinol 0.3% Night Concentrate](https://lovi.care/skincare/ae/p/no-7/pure-retinol-0-3-night-concentrate/for/dark-spots) — High fit - [Olay Collagen Peptide 24 Eye Cream](https://lovi.care/skincare/ae/p/olay/collagen-peptide-24-eye-cream/for/mature-skin) — Superior fit ## Questions and answers ### Can you use tretinoin and collagen peptide together? You should keep [tretinoin](https://lovi.care/skincare/ae/ingredients/tretinoin) and [collagen peptide](https://lovi.care/skincare/ae/ingredients/collagen-peptide) apart in your routine because combining them may increase irritation. Instead, alternate their usage by applying your retinoid in the PM and peptides in the AM. ### Which goes first, tretinoin or collagen peptide? Keep tretinoin and collagen peptide apart in your routine because combining them may increase irritation. Instead, try using your retinoid in the evening and peptides in the morning. ### Are tretinoin and collagen peptide good for sensitive skin? Keep tretinoin and collagen peptide apart in your routine because combining them may increase irritation. Instead, alternate their usage by applying tretinoin in the evening and peptides in the morning. ## Research on tretinoin and collagen peptide - [Restoration of collagen formation in photodamaged human skin by tretinoin (retinoic acid)](https://pubmed.ncbi.nlm.nih.gov/8336752/) Tretinoin · The New England Journal of Medicine, 1993 - [Clinical Assessment of New Topical Cream Containing Two Essential Oils Combined with Tretinoin in the Treatment of Acne](https://pubmed.ncbi.nlm.nih.gov/32210603/) Tretinoin · Clinical, Cosmetic and Investigational Dermatology, 2020 - [Collagen peptides affect collagen synthesis and the expression of collagen, elastin, and versican genes in cultured human dermal fibroblasts](https://pubmed.ncbi.nlm.nih.gov/38751975/) Collagen peptide · Frontiers in Medicine, 2024 - [Hydrolyzed Collagen Induces an Anti-Inflammatory Response That Induces Proliferation of Skin Fibroblast and Keratinocytes](https://pubmed.ncbi.nlm.nih.gov/36501011/) Collagen peptide · Nutrients, 2022 - [Efficacy assessments of tretinoin-loaded nano lipid carriers in acne vulgaris: a double blind, split-face randomized clinical study](https://pubmed.ncbi.nlm.nih.gov/34146120/) Tretinoin · Archives of Dermatological Research, 2022 - [Topical tretinoin for treating photoaging: A systematic review of randomized controlled trials](https://pubmed.ncbi.nlm.nih.gov/35620028/) Tretinoin · International Journal of Women's Dermatology, 2022 ## Other combinations - Keep them apart: [Tretinoin and acetyl hexapeptide-3](https://lovi.care/skincare/ae/ingredients/tretinoin-and-acetyl-hexapeptide-3) - Keep them apart: [Tretinoin and bio-placenta peptides](https://lovi.care/skincare/ae/ingredients/tretinoin-and-bio-placenta-peptides) - Keep them apart: [Adapalene and collagen peptide](https://lovi.care/skincare/ae/ingredients/adapalene-and-collagen-peptide) - Keep them apart: [Granactive retinoid and collagen peptide](https://lovi.care/skincare/ae/ingredients/granactive-retinoid-and-collagen-peptide) - Keep them apart: [Hydroxypinacolone retinoate and collagen peptide](https://lovi.care/skincare/ae/ingredients/hydroxypinacolone-retinoate-and-collagen-peptide) - Keep them apart: [Pro-retinol and collagen peptide](https://lovi.care/skincare/ae/ingredients/pro-retinol-and-collagen-peptide) - Keep them apart: [Retinal and collagen peptide](https://lovi.care/skincare/ae/ingredients/retinal-and-collagen-peptide) - Keep them apart: [Retinoid blend and collagen peptide](https://lovi.care/skincare/ae/ingredients/retinoid-blend-and-collagen-peptide) - Depends on the strength: [Retinol and collagen peptide](https://lovi.care/skincare/ae/ingredients/retinol-and-collagen-peptide) - Keep them apart: [Vitamin A and collagen peptide](https://lovi.care/skincare/ae/ingredients/vitamin-a-and-collagen-peptide) - Keep them apart: [Tretinoin and copper peptide](https://lovi.care/skincare/ae/ingredients/tretinoin-and-copper-peptide) - Keep them apart: [Tretinoin and hexapeptide](https://lovi.care/skincare/ae/ingredients/tretinoin-and-hexapeptide) - Keep them apart: [Tretinoin and hexapeptide-9](https://lovi.care/skincare/ae/ingredients/tretinoin-and-hexapeptide-9) - Keep them apart: [Tretinoin and palmitoyl pentapeptide-4](https://lovi.care/skincare/ae/ingredients/tretinoin-and-palmitoyl-pentapeptide-4) - Keep them apart: [Tretinoin and palmitoyl tripeptide-1](https://lovi.care/skincare/ae/ingredients/tretinoin-and-palmitoyl-tripeptide-1) - Keep them apart: [Tretinoin and peptide-rich plasma](https://lovi.care/skincare/ae/ingredients/tretinoin-and-peptide-rich-plasma) - Keep them apart: [Tretinoin and triple peptide blend](https://lovi.care/skincare/ae/ingredients/tretinoin-and-triple-peptide-blend) - Work well together: [Liposome and collagen peptide](https://lovi.care/skincare/ae/ingredients/liposome-and-collagen-peptide) - Work well together: [Microcapsule and collagen peptide](https://lovi.care/skincare/ae/ingredients/microcapsule-and-collagen-peptide) - Keep them apart: [Vitamin C and collagen peptide](https://lovi.care/skincare/ae/ingredients/vitamin-c-and-collagen-peptide) - Depends on the strength: [Niacinamide and tretinoin](https://lovi.care/skincare/ae/ingredients/niacinamide-and-tretinoin) - Work well together: [Collagen peptide and betaine](https://lovi.care/skincare/ae/ingredients/collagen-peptide-and-betaine) - Work well together: [Glycerin and collagen peptide](https://lovi.care/skincare/ae/ingredients/glycerin-and-collagen-peptide) - Work well together: [Hyaluronic acid and collagen peptide](https://lovi.care/skincare/ae/ingredients/hyaluronic-acid-and-collagen-peptide) - Depends on the strength: [Niacinamide and collagen peptide](https://lovi.care/skincare/ae/ingredients/niacinamide-and-collagen-peptide) - Work well together: [Panthenol and collagen peptide](https://lovi.care/skincare/ae/ingredients/panthenol-and-collagen-peptide) - Work well together: [Bakuchiol and collagen peptide](https://lovi.care/skincare/ae/ingredients/bakuchiol-and-collagen-peptide) - Work well together: [Arginine and collagen peptide](https://lovi.care/skincare/ae/ingredients/arginine-and-collagen-peptide) - Work well together: [Collagen peptide and GABA](https://lovi.care/skincare/ae/ingredients/collagen-peptide-and-gaba) - Work well together: [Silk amino acids and collagen peptide](https://lovi.care/skincare/ae/ingredients/silk-amino-acids-and-collagen-peptide) - Work well together: [Taurine and collagen peptide](https://lovi.care/skincare/ae/ingredients/taurine-and-collagen-peptide) - Work well together: [Collagen peptide and theanine](https://lovi.care/skincare/ae/ingredients/collagen-peptide-and-theanine) - Keep them apart: [AHA blend glycolic and citric acids and collagen peptide](https://lovi.care/skincare/ae/ingredients/aha-blend-glycolic-and-citric-acids-and-collagen-peptide) - Keep them apart: [Collagen peptide and citric acid](https://lovi.care/skincare/ae/ingredients/collagen-peptide-and-citric-acid) - Keep them apart: [Glycolic acid and collagen peptide](https://lovi.care/skincare/ae/ingredients/glycolic-acid-and-collagen-peptide) - Keep them apart: [Lactic acid and collagen peptide](https://lovi.care/skincare/ae/ingredients/lactic-acid-and-collagen-peptide) - Keep them apart: [Mandelic acid and collagen peptide](https://lovi.care/skincare/ae/ingredients/mandelic-acid-and-collagen-peptide) - Work well together: [Coenzyme Q10 and collagen peptide](https://lovi.care/skincare/ae/ingredients/coenzyme-q10-and-collagen-peptide) - Work well together: [Green tea and collagen peptide](https://lovi.care/skincare/ae/ingredients/green-tea-and-collagen-peptide) - Work well together: [Vitamin E and collagen peptide](https://lovi.care/skincare/ae/ingredients/vitamin-e-and-collagen-peptide) - Keep them apart: [AHA blend glycolic and citric acids and tretinoin](https://lovi.care/skincare/ae/ingredients/aha-blend-glycolic-and-citric-acids-and-tretinoin) - Keep them apart: [Tretinoin and citric acid](https://lovi.care/skincare/ae/ingredients/tretinoin-and-citric-acid) - Keep them apart: [Glycolic acid and tretinoin](https://lovi.care/skincare/ae/ingredients/glycolic-acid-and-tretinoin) - Keep them apart: [Tretinoin and lactic acid](https://lovi.care/skincare/ae/ingredients/tretinoin-and-lactic-acid) - Keep them apart: [Tretinoin and mandelic acid](https://lovi.care/skincare/ae/ingredients/tretinoin-and-mandelic-acid) - Work well together: [Collagen peptide and beta-sitosterol](https://lovi.care/skincare/ae/ingredients/collagen-peptide-and-beta-sitosterol) - Work well together: [Ceramide-building complex and collagen peptide](https://lovi.care/skincare/ae/ingredients/ceramide-building-complex-and-collagen-peptide) - Work well together: [Cholesterol and collagen peptide](https://lovi.care/skincare/ae/ingredients/cholesterol-and-collagen-peptide) - Work well together: [Collagen peptide and phytosphingosine](https://lovi.care/skincare/ae/ingredients/collagen-peptide-and-phytosphingosine) - Work well together: [Collagen peptide and phytosterol](https://lovi.care/skincare/ae/ingredients/collagen-peptide-and-phytosterol) - Work well together: [Collagen peptide and squalene](https://lovi.care/skincare/ae/ingredients/collagen-peptide-and-squalene) - Work well together: [Collagen peptide and tri-ceramide complex](https://lovi.care/skincare/ae/ingredients/collagen-peptide-and-tri-ceramide-complex) - Keep them apart: [Salicylic acid and collagen peptide](https://lovi.care/skincare/ae/ingredients/salicylic-acid-and-collagen-peptide) - Keep them apart: [Salicylic acid and tretinoin](https://lovi.care/skincare/ae/ingredients/salicylic-acid-and-tretinoin) - Keep them apart: [Vitamin C and tretinoin](https://lovi.care/skincare/ae/ingredients/vitamin-c-and-tretinoin) - Keep them apart: [Collagen peptide and baking soda](https://lovi.care/skincare/ae/ingredients/collagen-peptide-and-baking-soda) - Keep them apart: [Bleach and collagen peptide](https://lovi.care/skincare/ae/ingredients/bleach-and-collagen-peptide) - Keep them apart: [Potassium hydroxide and collagen peptide](https://lovi.care/skincare/ae/ingredients/potassium-hydroxide-and-collagen-peptide) - Keep them apart: [Collagen peptide and behenyl alcohol](https://lovi.care/skincare/ae/ingredients/collagen-peptide-and-behenyl-alcohol) - Keep them apart: [Collagen peptide and isopropyl alcohol](https://lovi.care/skincare/ae/ingredients/collagen-peptide-and-isopropyl-alcohol) - Keep them apart: [Polyvinyl alcohol and collagen peptide](https://lovi.care/skincare/ae/ingredients/polyvinyl-alcohol-and-collagen-peptide) - Keep them apart: [Copper and collagen peptide](https://lovi.care/skincare/ae/ingredients/copper-and-collagen-peptide) - Keep them apart: [Benzoyl peroxide and tretinoin](https://lovi.care/skincare/ae/ingredients/benzoyl-peroxide-and-tretinoin) - Keep them apart: [Magnesium and collagen peptide](https://lovi.care/skincare/ae/ingredients/magnesium-and-collagen-peptide) - Keep them apart: [Zinc and collagen peptide](https://lovi.care/skincare/ae/ingredients/zinc-and-collagen-peptide) - Keep them apart: [Zinc sulfate and collagen peptide](https://lovi.care/skincare/ae/ingredients/zinc-sulfate-and-collagen-peptide) - Keep them apart: [Benzoyl peroxide and collagen peptide](https://lovi.care/skincare/ae/ingredients/benzoyl-peroxide-and-collagen-peptide) - Keep them apart: [Azelaic acid and collagen peptide](https://lovi.care/skincare/ae/ingredients/azelaic-acid-and-collagen-peptide) - Keep them apart: [Collagen peptide and protease](https://lovi.care/skincare/ae/ingredients/collagen-peptide-and-protease) - Keep them apart: [Superoxide dismutase and collagen peptide](https://lovi.care/skincare/ae/ingredients/superoxide-dismutase-and-collagen-peptide) ## About the Lovi Fit Lovi: Unbiased, science-based skincare AI trained on real user outcomes. Lovi checks every pairing with brand-independent rules its dermatologists and cosmetic chemists build and review, and personalizes every pick with AI trained on the real results of millions of users. Lovi trains its fit score models on a proprietary dataset built from more than 10,000 expert-labeled products and more than 100,000 simulated examples, following an internally consistent methodology presented at Cosmoprof, AMWC, and Skin of Color Update. Levels from best to worst: Superior, High, Average, Low, Caution, Warning. Behind this pairing advice: Nadia Kapleva, MS (Co-founder, Medical Director); Alexey Shagraev, PhD (Co-founder, CEO and CTO); Dr. Sofía Perea Pérez, MD, MSc (Medical Board); Aishani Shah, MD (Medical Board); Asya Zubkova, MS (Medical Board); Hanna Kurets, MD (Medical Board, Medical Advisor); Elina Nazarenko, MD (Medical Board); Victoria Derkova, MS (Medical Board). Page built Nov 8, 2026. More from Lovi: https://lovi.care/skincare/llms.txt ## This page in other countries - United States: https://lovi.care/skincare/ingredients/tretinoin-and-collagen-peptide - United Kingdom: https://lovi.care/skincare/uk/ingredients/tretinoin-and-collagen-peptide - Ireland: https://lovi.care/skincare/ie/ingredients/tretinoin-and-collagen-peptide - Germany: https://lovi.care/skincare/de/ingredients/tretinoin-and-collagen-peptide - France: https://lovi.care/skincare/fr/ingredients/tretinoin-and-collagen-peptide - Italy: https://lovi.care/skincare/it/ingredients/tretinoin-and-collagen-peptide - Netherlands: https://lovi.care/skincare/nl/ingredients/tretinoin-and-collagen-peptide - Spain: https://lovi.care/skincare/es/ingredients/tretinoin-and-collagen-peptide - Canada: https://lovi.care/skincare/ca/ingredients/tretinoin-and-collagen-peptide - Australia: https://lovi.care/skincare/au/ingredients/tretinoin-and-collagen-peptide - Singapore: https://lovi.care/skincare/sg/ingredients/tretinoin-and-collagen-peptide - Saudi Arabia: https://lovi.care/skincare/sa/ingredients/tretinoin-and-collagen-peptide - United Arab Emirates: https://lovi.care/skincare/ae/ingredients/tretinoin-and-collagen-peptide (this page)