# Superoxide dismutase Page: https://lovi.care/skincare/ae/ingredients/superoxide-dismutase The Lovi Fit is the same in every country; only the stores and prices differ, and the ones here are for the United Arab Emirates. Superoxide dismutase protects the skin by visibly calming redness, reducing UV-induced irritation, and lowering oxidative lipid stress for a healthier barrier. This powerhouse ingredient suits both dry skin and oily skin types, and it is most commonly found in lightweight [serums](https://lovi.care/skincare/ae/ingredients/serum). You can easily add it to your daily routine, but be sure to keep it apart from [bio-placenta peptides](https://lovi.care/skincare/ae/ingredients/bio-placenta-peptides), [hexapeptide](https://lovi.care/skincare/ae/ingredients/hexapeptide), and [acetyl hexapeptide-3](https://lovi.care/skincare/ae/ingredients/acetyl-hexapeptide-3). [European Journal of Pharmaceutics and Biopharmaceutics, 2016](https://pubmed.ncbi.nlm.nih.gov/27460952/) [International Journal of Cosmetic Science, 2004](https://pubmed.ncbi.nlm.nih.gov/18492138/) This page shows superoxide dismutase products with a Lovi page. For every product, and a routine built for your skin, use the Lovi app. ### Popular superoxide dismutase products - [iS Clinical Reparative Moisture Emulsion](https://lovi.care/skincare/ae/p/is-clinical/reparative-moisture-emulsion/for/dry-skin) — High fit - [U Beauty Resurfacing Compound](https://lovi.care/skincare/ae/p/u-beauty/resurfacing-compound/for/dark-spots) — High fit — [AED 829.22 at Amazon](https://www.amazon.ae/dp/B089B887ZZ?tag=lovi00-21&linkCode=osi&th=1&psc=1) - [Skinbetter Science Alto Advanced Defense and Repair Serum](https://lovi.care/skincare/ae/p/skinbetter-science/alto-advanced-defense-and-repair-serum/for/dry-sensitive-skin) — High fit - [Skin Better Science Alto Advanced Defense and Repair Serum](https://lovi.care/skincare/ae/p/skin-better-science/alto-advanced-defense-and-repair-serum/for/dry-skin) — High fit - [Skinbetter Science Alto Defense Serum](https://lovi.care/skincare/ae/p/skinbetter-science/alto-defense-serum/for/dark-spots) — High fit - [NIOD Modulating Glucosides](https://lovi.care/skincare/ae/p/niod/modulating-glucosides/for/mature-skin) — High fit - [Charlotte Tilbury Magic Eye Rescue](https://lovi.care/skincare/ae/p/charlotte-tilbury/magic-eye-rescue/for/dark-spots) — Average fit — [AED 320.00 at Amazon](https://www.amazon.ae/dp/B01KYS49J0?tag=lovi00-21&linkCode=osi&th=1&psc=1) - [Paula's Choice RESIST Super Antioxidant Concentrate Serum](https://lovi.care/skincare/ae/p/paula-s-choice/resist-super-antioxidant-concentrate-serum/for/sensitive-skin) — Superior fit — [AED 347.75 at Amazon](https://www.amazon.ae/dp/B00EEGEI7C?tag=lovi00-21&linkCode=osi&th=1&psc=1) ### Superoxide dismutase [serums](https://lovi.care/skincare/ae/ingredients/serum) - [Skinbetter Science Alto Advanced Defense and Repair Serum](https://lovi.care/skincare/ae/p/skinbetter-science/alto-advanced-defense-and-repair-serum/for/dry-sensitive-skin) — High fit - [Skin Better Science Alto Advanced Defense and Repair Serum](https://lovi.care/skincare/ae/p/skin-better-science/alto-advanced-defense-and-repair-serum/for/dry-skin) — High fit - [Skinbetter Science Alto Defense Serum](https://lovi.care/skincare/ae/p/skinbetter-science/alto-defense-serum/for/dark-spots) — High fit - [NIOD Modulating Glucosides](https://lovi.care/skincare/ae/p/niod/modulating-glucosides/for/mature-skin) — High fit - [Paula's Choice RESIST Super Antioxidant Concentrate Serum](https://lovi.care/skincare/ae/p/paula-s-choice/resist-super-antioxidant-concentrate-serum/for/sensitive-skin) — Superior fit — [AED 347.75 at Amazon](https://www.amazon.ae/dp/B00EEGEI7C?tag=lovi00-21&linkCode=osi&th=1&psc=1) ## What reviewers say about popular superoxide dismutase products The highlight reviewers mention most for each popular superoxide dismutase product on Lovi. - iS Clinical Reparative Moisture Emulsion Deeply hydrating ★4.6 · 600+ reviews Lightweight, non-greasy Improves skin texture “Real moisture punch” [What people say about Reparative Moisture Emulsion](https://lovi.care/skincare/ae/p/is-clinical/reparative-moisture-emulsion/for/dry-skin) - U Beauty Resurfacing Compound Smoother skin texture ★4.5 · 500+ reviews Brightens and evens Simplifies routine “skin feels like butter” [What people say about Resurfacing Compound](https://lovi.care/skincare/ae/p/u-beauty/resurfacing-compound/for/dark-spots) - Skinbetter Science Alto Advanced Defense and Repair Serum Elegant texture ★4.8 · 200+ reviews High price point Improves radiance “Feels lightweight and silky” [What people say about Alto Advanced Defense and Repair Serum](https://lovi.care/skincare/ae/p/skinbetter-science/alto-advanced-defense-and-repair-serum/for/dry-sensitive-skin) - Skinbetter Science Alto Defense Serum Improves skin texture ★4.8 · 200+ reviews Reduces skin redness Expensive product “evened out my tone and texture so well” [What people say about Alto Defense Serum](https://lovi.care/skincare/ae/p/skinbetter-science/alto-defense-serum/for/dark-spots) - NIOD Modulating Glucosides Calms sensitive skin ★4.8 · 400+ reviews Reduces skin redness Buffers active irritation “Like medicine to irritated skin.” [What people say about Modulating Glucosides](https://lovi.care/skincare/ae/p/niod/modulating-glucosides/for/mature-skin) - Charlotte Tilbury Magic Eye Rescue Intensely hydrating ★4.3 · 700+ reviews Expensive price Brightens dark circles “extremely emollient and rich” [What people say about Magic Eye Rescue](https://lovi.care/skincare/ae/p/charlotte-tilbury/magic-eye-rescue/for/dark-spots) ### Other superoxide dismutase products - [iS Clinical Reparative Moisture Emulsion](https://lovi.care/skincare/ae/p/is-clinical/reparative-moisture-emulsion/for/dry-skin) — High fit - [U Beauty Resurfacing Compound](https://lovi.care/skincare/ae/p/u-beauty/resurfacing-compound/for/dark-spots) — High fit — [AED 829.22 at Amazon](https://www.amazon.ae/dp/B089B887ZZ?tag=lovi00-21&linkCode=osi&th=1&psc=1) - [Charlotte Tilbury Magic Eye Rescue](https://lovi.care/skincare/ae/p/charlotte-tilbury/magic-eye-rescue/for/dark-spots) — Average fit — [AED 320.00 at Amazon](https://www.amazon.ae/dp/B01KYS49J0?tag=lovi00-21&linkCode=osi&th=1&psc=1) - [Image Skincare Vital C Hydrating Enzyme Masque](https://lovi.care/skincare/ae/p/image-skincare/vital-c-hydrating-enzyme-masque/for/mature-skin) — High fit - [Dr. Dennis Gross C + Collagen Biocellulose Brightening Treatment Mask](https://lovi.care/skincare/ae/p/dr-dennis-gross/c-collagen-biocellulose-brightening-treatment-mask/for/mature-skin) — High fit — [AED 200.69 at Amazon](https://www.amazon.ae/dp/B0BS4FVQZ4?tag=lovi00-21&linkCode=osi&th=1&psc=1) - [NIOD Superoxide Dismutase Saccharide Mist](https://lovi.care/skincare/ae/p/niod/superoxide-dismutase-saccharide-mist/for/dry-sensitive-skin) — Average fit ### Superoxide dismutase for dry skin - [Paula's Choice RESIST Super Antioxidant Concentrate Serum](https://lovi.care/skincare/ae/p/paula-s-choice/resist-super-antioxidant-concentrate-serum/for/dry-skin) — Superior fit — [AED 347.75 at Amazon](https://www.amazon.ae/dp/B00EEGEI7C?tag=lovi00-21&linkCode=osi&th=1&psc=1) - [Image Skincare Vital C Hydrating Enzyme Masque](https://lovi.care/skincare/ae/p/image-skincare/vital-c-hydrating-enzyme-masque/for/dry-skin) — High fit - [Skin Better Science Alto Advanced Defense and Repair Serum](https://lovi.care/skincare/ae/p/skin-better-science/alto-advanced-defense-and-repair-serum/for/dry-skin) — High fit - [Skinbetter Science Alto Advanced Defense and Repair Serum](https://lovi.care/skincare/ae/p/skinbetter-science/alto-advanced-defense-and-repair-serum/for/dry-skin) — High fit - [NIOD Modulating Glucosides](https://lovi.care/skincare/ae/p/niod/modulating-glucosides/for/dry-skin) — High fit - [iS Clinical Reparative Moisture Emulsion](https://lovi.care/skincare/ae/p/is-clinical/reparative-moisture-emulsion/for/dry-skin) — High fit - [Skinbetter Science Alto Defense Serum](https://lovi.care/skincare/ae/p/skinbetter-science/alto-defense-serum/for/dry-skin) — Average fit - [Dr. Dennis Gross C + Collagen Biocellulose Brightening Treatment Mask](https://lovi.care/skincare/ae/p/dr-dennis-gross/c-collagen-biocellulose-brightening-treatment-mask/for/dry-skin) — Average fit — [AED 200.69 at Amazon](https://www.amazon.ae/dp/B0BS4FVQZ4?tag=lovi00-21&linkCode=osi&th=1&psc=1) - [NIOD Superoxide Dismutase Saccharide Mist](https://lovi.care/skincare/ae/p/niod/superoxide-dismutase-saccharide-mist/for/dry-skin) — Average fit - [Charlotte Tilbury Magic Eye Rescue](https://lovi.care/skincare/ae/p/charlotte-tilbury/magic-eye-rescue/for/dry-skin) — Average fit — [AED 320.00 at Amazon](https://www.amazon.ae/dp/B01KYS49J0?tag=lovi00-21&linkCode=osi&th=1&psc=1) - [U Beauty Resurfacing Compound](https://lovi.care/skincare/ae/p/u-beauty/resurfacing-compound/for/dry-skin) — Average fit — [AED 829.22 at Amazon](https://www.amazon.ae/dp/B089B887ZZ?tag=lovi00-21&linkCode=osi&th=1&psc=1) ### Superoxide dismutase for oily skin - [Paula's Choice RESIST Super Antioxidant Concentrate Serum](https://lovi.care/skincare/ae/p/paula-s-choice/resist-super-antioxidant-concentrate-serum/for/oily-skin) — High fit — [AED 347.75 at Amazon](https://www.amazon.ae/dp/B00EEGEI7C?tag=lovi00-21&linkCode=osi&th=1&psc=1) - [Image Skincare Vital C Hydrating Enzyme Masque](https://lovi.care/skincare/ae/p/image-skincare/vital-c-hydrating-enzyme-masque/for/oily-skin) — High fit - [Dr. Dennis Gross C + Collagen Biocellulose Brightening Treatment Mask](https://lovi.care/skincare/ae/p/dr-dennis-gross/c-collagen-biocellulose-brightening-treatment-mask/for/oily-skin) — Average fit — [AED 200.69 at Amazon](https://www.amazon.ae/dp/B0BS4FVQZ4?tag=lovi00-21&linkCode=osi&th=1&psc=1) - [Skinbetter Science Alto Advanced Defense and Repair Serum](https://lovi.care/skincare/ae/p/skinbetter-science/alto-advanced-defense-and-repair-serum/for/oily-skin) — Average fit - [NIOD Superoxide Dismutase Saccharide Mist](https://lovi.care/skincare/ae/p/niod/superoxide-dismutase-saccharide-mist/for/oily-skin) — Average fit - [U Beauty Resurfacing Compound](https://lovi.care/skincare/ae/p/u-beauty/resurfacing-compound/for/oily-skin) — Average fit — [AED 829.22 at Amazon](https://www.amazon.ae/dp/B089B887ZZ?tag=lovi00-21&linkCode=osi&th=1&psc=1) - [iS Clinical Reparative Moisture Emulsion](https://lovi.care/skincare/ae/p/is-clinical/reparative-moisture-emulsion/for/oily-skin) — Average fit - [NIOD Modulating Glucosides](https://lovi.care/skincare/ae/p/niod/modulating-glucosides/for/oily-skin) — Average fit - [Skin Better Science Alto Advanced Defense and Repair Serum](https://lovi.care/skincare/ae/p/skin-better-science/alto-advanced-defense-and-repair-serum/for/oily-skin) — Average fit - [Skinbetter Science Alto Defense Serum](https://lovi.care/skincare/ae/p/skinbetter-science/alto-defense-serum/for/oily-skin) — Average fit - [Charlotte Tilbury Magic Eye Rescue](https://lovi.care/skincare/ae/p/charlotte-tilbury/magic-eye-rescue/for/oily-skin) — Low fit — [AED 320.00 at Amazon](https://www.amazon.ae/dp/B01KYS49J0?tag=lovi00-21&linkCode=osi&th=1&psc=1) ### Superoxide dismutase for combination skin - [Paula's Choice RESIST Super Antioxidant Concentrate Serum](https://lovi.care/skincare/ae/p/paula-s-choice/resist-super-antioxidant-concentrate-serum/for/combination-skin) — High fit — [AED 347.75 at Amazon](https://www.amazon.ae/dp/B00EEGEI7C?tag=lovi00-21&linkCode=osi&th=1&psc=1) - [NIOD Modulating Glucosides](https://lovi.care/skincare/ae/p/niod/modulating-glucosides/for/combination-skin) — High fit - [Dr. Dennis Gross C + Collagen Biocellulose Brightening Treatment Mask](https://lovi.care/skincare/ae/p/dr-dennis-gross/c-collagen-biocellulose-brightening-treatment-mask/for/combination-skin) — Average fit — [AED 200.69 at Amazon](https://www.amazon.ae/dp/B0BS4FVQZ4?tag=lovi00-21&linkCode=osi&th=1&psc=1) - [U Beauty Resurfacing Compound](https://lovi.care/skincare/ae/p/u-beauty/resurfacing-compound/for/combination-skin) — Average fit — [AED 829.22 at Amazon](https://www.amazon.ae/dp/B089B887ZZ?tag=lovi00-21&linkCode=osi&th=1&psc=1) - [Image Skincare Vital C Hydrating Enzyme Masque](https://lovi.care/skincare/ae/p/image-skincare/vital-c-hydrating-enzyme-masque/for/combination-skin) — Average fit - [Skinbetter Science Alto Advanced Defense and Repair Serum](https://lovi.care/skincare/ae/p/skinbetter-science/alto-advanced-defense-and-repair-serum/for/combination-skin) — Average fit - [NIOD Superoxide Dismutase Saccharide Mist](https://lovi.care/skincare/ae/p/niod/superoxide-dismutase-saccharide-mist/for/combination-skin) — Average fit - [iS Clinical Reparative Moisture Emulsion](https://lovi.care/skincare/ae/p/is-clinical/reparative-moisture-emulsion/for/combination-skin) — Average fit - [Skin Better Science Alto Advanced Defense and Repair Serum](https://lovi.care/skincare/ae/p/skin-better-science/alto-advanced-defense-and-repair-serum/for/combination-skin) — Average fit - [Skinbetter Science Alto Defense Serum](https://lovi.care/skincare/ae/p/skinbetter-science/alto-defense-serum/for/combination-skin) — Average fit - [Charlotte Tilbury Magic Eye Rescue](https://lovi.care/skincare/ae/p/charlotte-tilbury/magic-eye-rescue/for/combination-skin) — Average fit — [AED 320.00 at Amazon](https://www.amazon.ae/dp/B01KYS49J0?tag=lovi00-21&linkCode=osi&th=1&psc=1) ### Superoxide dismutase for sensitive skin - [Paula's Choice RESIST Super Antioxidant Concentrate Serum](https://lovi.care/skincare/ae/p/paula-s-choice/resist-super-antioxidant-concentrate-serum/for/sensitive-skin) — Superior fit — [AED 347.75 at Amazon](https://www.amazon.ae/dp/B00EEGEI7C?tag=lovi00-21&linkCode=osi&th=1&psc=1) - [NIOD Modulating Glucosides](https://lovi.care/skincare/ae/p/niod/modulating-glucosides/for/sensitive-skin) — High fit - [Image Skincare Vital C Hydrating Enzyme Masque](https://lovi.care/skincare/ae/p/image-skincare/vital-c-hydrating-enzyme-masque/for/sensitive-skin) — High fit - [Skinbetter Science Alto Advanced Defense and Repair Serum](https://lovi.care/skincare/ae/p/skinbetter-science/alto-advanced-defense-and-repair-serum/for/sensitive-skin) — Average fit - [NIOD Superoxide Dismutase Saccharide Mist](https://lovi.care/skincare/ae/p/niod/superoxide-dismutase-saccharide-mist/for/sensitive-skin) — Average fit - [Skinbetter Science Alto Defense Serum](https://lovi.care/skincare/ae/p/skinbetter-science/alto-defense-serum/for/sensitive-skin) — Average fit - [Dr. Dennis Gross C + Collagen Biocellulose Brightening Treatment Mask](https://lovi.care/skincare/ae/p/dr-dennis-gross/c-collagen-biocellulose-brightening-treatment-mask/for/sensitive-skin) — Average fit — [AED 200.69 at Amazon](https://www.amazon.ae/dp/B0BS4FVQZ4?tag=lovi00-21&linkCode=osi&th=1&psc=1) - [iS Clinical Reparative Moisture Emulsion](https://lovi.care/skincare/ae/p/is-clinical/reparative-moisture-emulsion/for/sensitive-skin) — Average fit - [Skin Better Science Alto Advanced Defense and Repair Serum](https://lovi.care/skincare/ae/p/skin-better-science/alto-advanced-defense-and-repair-serum/for/sensitive-skin) — Average fit - [U Beauty Resurfacing Compound](https://lovi.care/skincare/ae/p/u-beauty/resurfacing-compound/for/sensitive-skin) — Average fit — [AED 829.22 at Amazon](https://www.amazon.ae/dp/B089B887ZZ?tag=lovi00-21&linkCode=osi&th=1&psc=1) - [Charlotte Tilbury Magic Eye Rescue](https://lovi.care/skincare/ae/p/charlotte-tilbury/magic-eye-rescue/for/sensitive-skin) — Average fit — [AED 320.00 at Amazon](https://www.amazon.ae/dp/B01KYS49J0?tag=lovi00-21&linkCode=osi&th=1&psc=1) ### Superoxide dismutase for acne-prone skin - [Paula's Choice RESIST Super Antioxidant Concentrate Serum](https://lovi.care/skincare/ae/p/paula-s-choice/resist-super-antioxidant-concentrate-serum/for/acne-prone-skin) — High fit — [AED 347.75 at Amazon](https://www.amazon.ae/dp/B00EEGEI7C?tag=lovi00-21&linkCode=osi&th=1&psc=1) - [Dr. Dennis Gross C + Collagen Biocellulose Brightening Treatment Mask](https://lovi.care/skincare/ae/p/dr-dennis-gross/c-collagen-biocellulose-brightening-treatment-mask/for/acne-prone-skin) — High fit — [AED 200.69 at Amazon](https://www.amazon.ae/dp/B0BS4FVQZ4?tag=lovi00-21&linkCode=osi&th=1&psc=1) - [Image Skincare Vital C Hydrating Enzyme Masque](https://lovi.care/skincare/ae/p/image-skincare/vital-c-hydrating-enzyme-masque/for/acne-prone-skin) — High fit - [iS Clinical Reparative Moisture Emulsion](https://lovi.care/skincare/ae/p/is-clinical/reparative-moisture-emulsion/for/acne-prone-skin) — High fit - [NIOD Modulating Glucosides](https://lovi.care/skincare/ae/p/niod/modulating-glucosides/for/acne-prone-skin) — Average fit - [U Beauty Resurfacing Compound](https://lovi.care/skincare/ae/p/u-beauty/resurfacing-compound/for/acne-prone-skin) — Average fit — [AED 829.22 at Amazon](https://www.amazon.ae/dp/B089B887ZZ?tag=lovi00-21&linkCode=osi&th=1&psc=1) - [Skinbetter Science Alto Advanced Defense and Repair Serum](https://lovi.care/skincare/ae/p/skinbetter-science/alto-advanced-defense-and-repair-serum/for/acne-prone-skin) — Average fit - [Charlotte Tilbury Magic Eye Rescue](https://lovi.care/skincare/ae/p/charlotte-tilbury/magic-eye-rescue/for/acne-prone-skin) — Average fit — [AED 320.00 at Amazon](https://www.amazon.ae/dp/B01KYS49J0?tag=lovi00-21&linkCode=osi&th=1&psc=1) - [NIOD Superoxide Dismutase Saccharide Mist](https://lovi.care/skincare/ae/p/niod/superoxide-dismutase-saccharide-mist/for/acne-prone-skin) — Average fit - [Skinbetter Science Alto Defense Serum](https://lovi.care/skincare/ae/p/skinbetter-science/alto-defense-serum/for/acne-prone-skin) — Average fit - [Skin Better Science Alto Advanced Defense and Repair Serum](https://lovi.care/skincare/ae/p/skin-better-science/alto-advanced-defense-and-repair-serum/for/acne-prone-skin) — Average fit ## What to combine superoxide dismutase with Ingredient Together How to use them [Bio-placenta peptides](https://lovi.care/skincare/ae/ingredients/bio-placenta-peptides) Keep apart Use them at different times of day, applying the peptides in the morning and superoxide dismutase at night, because they clash and cancel each other out. [Superoxide dismutase and bio-placenta peptides](https://lovi.care/skincare/ae/ingredients/bio-placenta-peptides-and-superoxide-dismutase) [Hexapeptide](https://lovi.care/skincare/ae/ingredients/hexapeptide) Keep apart Use them at different times of day, applying [hexapeptide](https://lovi.care/skincare/ae/ingredients/hexapeptide) in the morning and superoxide dismutase at night, because their active structures clash. [Superoxide dismutase and hexapeptide](https://lovi.care/skincare/ae/ingredients/hexapeptide-and-superoxide-dismutase) [Acetyl hexapeptide-3](https://lovi.care/skincare/ae/ingredients/acetyl-hexapeptide-3) Keep apart Use them at different times of day, applying the peptide first and the enzyme later, because they cancel each other out. [Superoxide dismutase and acetyl hexapeptide-3](https://lovi.care/skincare/ae/ingredients/acetyl-hexapeptide-3-and-superoxide-dismutase) [Collagen peptide](https://lovi.care/skincare/ae/ingredients/collagen-peptide) Keep apart Use them at different times of day, applying the peptide first, because enzymes can break down peptides. [Superoxide dismutase and collagen peptide](https://lovi.care/skincare/ae/ingredients/superoxide-dismutase-and-collagen-peptide) [Copper peptide](https://lovi.care/skincare/ae/ingredients/copper-peptide) Keep apart Use them at different times of day, applying [copper peptide](https://lovi.care/skincare/ae/ingredients/copper-peptide) in the morning and superoxide dismutase at night. [Superoxide dismutase and copper peptide](https://lovi.care/skincare/ae/ingredients/superoxide-dismutase-and-copper-peptide) [Hexapeptide-9](https://lovi.care/skincare/ae/ingredients/hexapeptide-9) Keep apart Use them at different times of day, applying superoxide dismutase first and [hexapeptide-9](https://lovi.care/skincare/ae/ingredients/hexapeptide-9) later, because mixing them breaks down the active ingredients. [Superoxide dismutase and hexapeptide-9](https://lovi.care/skincare/ae/ingredients/superoxide-dismutase-and-hexapeptide-9) [Peptide-rich plasma](https://lovi.care/skincare/ae/ingredients/peptide-rich-plasma) Keep apart Use them at different times of day, applying the peptide product in the morning and superoxide dismutase at night. [Superoxide dismutase and peptide-rich plasma](https://lovi.care/skincare/ae/ingredients/superoxide-dismutase-and-peptide-rich-plasma) [Triple peptide blend](https://lovi.care/skincare/ae/ingredients/triple-peptide-blend) Keep apart Use them at different times of day, applying the peptide blend first and the enzyme later, because they cancel each other out. [Superoxide dismutase and triple peptide blend](https://lovi.care/skincare/ae/ingredients/superoxide-dismutase-and-triple-peptide-blend) [Palmitoyl pentapeptide-4](https://lovi.care/skincare/ae/ingredients/palmitoyl-pentapeptide-4) Keep apart Use them at different times of day, applying superoxide dismutase first and [palmitoyl pentapeptide-4](https://lovi.care/skincare/ae/ingredients/palmitoyl-pentapeptide-4) later, to prevent the enzyme from breaking down the peptide. [Superoxide dismutase and palmitoyl pentapeptide-4](https://lovi.care/skincare/ae/ingredients/superoxide-dismutase-and-palmitoyl-pentapeptide-4) [Palmitoyl tripeptide-1](https://lovi.care/skincare/ae/ingredients/palmitoyl-tripeptide-1) Keep apart Use superoxide dismutase and [palmitoyl tripeptide-1](https://lovi.care/skincare/ae/ingredients/palmitoyl-tripeptide-1) at different times of day, applying the enzyme product in the morning and the peptide at night. [Superoxide dismutase and palmitoyl tripeptide-1](https://lovi.care/skincare/ae/ingredients/superoxide-dismutase-and-palmitoyl-tripeptide-1) From the ingredient rules behind the "Works well with" and "Don't mix with" notes on every product in the Lovi app. ## Questions and answers ### What does superoxide dismutase do for the skin? Superoxide dismutase helps defend the skin against environmental damage by reducing UV-induced redness and minimizing lipid peroxides on the skin surface. [European Journal of Pharmaceutics and Biopharmaceutics, 2016](https://pubmed.ncbi.nlm.nih.gov/27460952/) [International Journal of Cosmetic Science, 2004](https://pubmed.ncbi.nlm.nih.gov/18492138/) ### How do you use superoxide dismutase? You can use superoxide dismutase at night to help protect your skin, but you should keep it apart from certain peptides by using them at different times of day. ### Should you use superoxide dismutase in the morning or at night? You can use superoxide dismutase in the morning or at night, but if you use it with certain peptides like bio-placenta or [copper peptides](https://lovi.care/skincare/ae/ingredients/copper-peptide), you should use them at different times of day. Applying superoxide dismutase helps protect your skin from sun damage and oxidative stress. [European Journal of Pharmaceutics and Biopharmaceutics, 2016](https://pubmed.ncbi.nlm.nih.gov/27460952/) [International Journal of Cosmetic Science, 2004](https://pubmed.ncbi.nlm.nih.gov/18492138/) ### Can you use superoxide dismutase every day? Yes, you can use superoxide dismutase every day to help protect your skin against sun damage and reduce irritation. Topical application helps suppress UV-induced redness and sunburn cell formation. [European Journal of Pharmaceutics and Biopharmaceutics, 2016](https://pubmed.ncbi.nlm.nih.gov/27460952/) [International Journal of Cosmetic Science, 2004](https://pubmed.ncbi.nlm.nih.gov/18492138/) ### Does superoxide dismutase cause purging or irritation? Superoxide dismutase is unlikely to cause purging or irritation, as it functions primarily as an antioxidant that helps protect skin against environmental damage. Topical treatment helps soothe the skin and reduce redness or inflammation from UV exposure. [European Journal of Pharmaceutics and Biopharmaceutics, 2016](https://pubmed.ncbi.nlm.nih.gov/27460952/) [International Journal of Cosmetic Science, 2004](https://pubmed.ncbi.nlm.nih.gov/18492138/) ### Which skin types is superoxide dismutase best for? Superoxide dismutase is best for dry skin, sensitive skin, dry sensitive skin, and skin with dark spots with Paula's Choice RESIST Super Antioxidant Concentrate [Serum](https://lovi.care/skincare/ae/ingredients/serum), which Lovi rates as a Superior fit. It also works well for oily skin, combination skin, acne-prone skin, mature skin, and oily acne-prone skin with top-rated options like Paula's Choice RESIST Super Antioxidant Concentrate Serum, Image Skincare Vital C Hydrating Enzyme Masque, and NIOD Modulating Glucosides. ### Can you use superoxide dismutase with bio-placenta peptides? No, you cannot use superoxide dismutase and [bio-placenta peptides](https://lovi.care/skincare/ae/ingredients/bio-placenta-peptides) together because they clash and cancel each other out. Use them at different times of day by applying the peptides in the morning and superoxide dismutase at night. ## Research on superoxide dismutase - [Topical application of superoxide dismutase mediated by HIV-TAT peptide attenuates UVB-induced damages in human skin](https://pubmed.ncbi.nlm.nih.gov/27460952/) Superoxide dismutase · European Journal of Pharmaceutics and Biopharmaceutics, 2016 - [Use of the synthetic superoxide dismutase/catalase mimetic EUK-134 to compensate for seasonal antioxidant deficiency by reducing pre-existing lipid peroxides at the human skin surface](https://pubmed.ncbi.nlm.nih.gov/18492138/) Superoxide dismutase · International Journal of Cosmetic Science, 2004 ## Combining superoxide dismutase - Keep them apart: [Acetyl hexapeptide-3 and superoxide dismutase](https://lovi.care/skincare/ae/ingredients/acetyl-hexapeptide-3-and-superoxide-dismutase) - Keep them apart: [Bio-placenta peptides and superoxide dismutase](https://lovi.care/skincare/ae/ingredients/bio-placenta-peptides-and-superoxide-dismutase) - Keep them apart: [Superoxide dismutase and collagen peptide](https://lovi.care/skincare/ae/ingredients/superoxide-dismutase-and-collagen-peptide) - Keep them apart: [Superoxide dismutase and copper peptide](https://lovi.care/skincare/ae/ingredients/superoxide-dismutase-and-copper-peptide) - Keep them apart: [Hexapeptide and superoxide dismutase](https://lovi.care/skincare/ae/ingredients/hexapeptide-and-superoxide-dismutase) - Keep them apart: [Superoxide dismutase and hexapeptide-9](https://lovi.care/skincare/ae/ingredients/superoxide-dismutase-and-hexapeptide-9) - Keep them apart: [Superoxide dismutase and palmitoyl pentapeptide-4](https://lovi.care/skincare/ae/ingredients/superoxide-dismutase-and-palmitoyl-pentapeptide-4) - Keep them apart: [Superoxide dismutase and palmitoyl tripeptide-1](https://lovi.care/skincare/ae/ingredients/superoxide-dismutase-and-palmitoyl-tripeptide-1) - Keep them apart: [Superoxide dismutase and peptide-rich plasma](https://lovi.care/skincare/ae/ingredients/superoxide-dismutase-and-peptide-rich-plasma) - Keep them apart: [Superoxide dismutase and triple peptide blend](https://lovi.care/skincare/ae/ingredients/superoxide-dismutase-and-triple-peptide-blend) ## Brands with superoxide dismutase - American skincare: [Paula's Choice](https://lovi.care/skincare/ae/brands/paula-s-choice) - British skincare: [Charlotte Tilbury](https://lovi.care/skincare/ae/brands/charlotte-tilbury) - American skincare: [Skinbetter Science](https://lovi.care/skincare/ae/brands/skinbetter-science) - American skincare: [Image Skincare](https://lovi.care/skincare/ae/brands/image-skincare) - American skincare: [iS Clinical](https://lovi.care/skincare/ae/brands/is-clinical) - American skincare: [U Beauty](https://lovi.care/skincare/ae/brands/u-beauty) - Canadian skincare: [NIOD](https://lovi.care/skincare/ae/brands/niod) - American skincare: [Skin Better Science](https://lovi.care/skincare/ae/brands/skin-better-science) - American skincare: [Dr. Dennis Gross](https://lovi.care/skincare/ae/brands/dr-dennis-gross) ## Related ingredients - [Bio-placenta peptides](https://lovi.care/skincare/ae/ingredients/bio-placenta-peptides) - [Hexapeptide](https://lovi.care/skincare/ae/ingredients/hexapeptide) - [Acetyl hexapeptide-3](https://lovi.care/skincare/ae/ingredients/acetyl-hexapeptide-3) - [Collagen peptide](https://lovi.care/skincare/ae/ingredients/collagen-peptide) - [Copper peptide](https://lovi.care/skincare/ae/ingredients/copper-peptide) - [Hexapeptide-9](https://lovi.care/skincare/ae/ingredients/hexapeptide-9) - [Peptide-rich plasma](https://lovi.care/skincare/ae/ingredients/peptide-rich-plasma) - [Triple peptide blend](https://lovi.care/skincare/ae/ingredients/triple-peptide-blend) - [Palmitoyl pentapeptide-4](https://lovi.care/skincare/ae/ingredients/palmitoyl-pentapeptide-4) - [Palmitoyl tripeptide-1](https://lovi.care/skincare/ae/ingredients/palmitoyl-tripeptide-1) ## About the Lovi Fit Lovi: Unbiased, science-based skincare AI trained on real user outcomes. Lovi checks every ingredient with brand-independent rules its dermatologists and cosmetic chemists build and review, and personalizes every pick with AI trained on the real results of millions of users. Lovi trains its fit score models on a proprietary dataset built from more than 10,000 expert-labeled products and more than 100,000 simulated examples, following an internally consistent methodology presented at Cosmoprof, AMWC, and Skin of Color Update. Levels from best to worst: Superior, High, Average, Low, Caution, Warning. Behind this ingredient guide: Nadia Kapleva, MS (Co-founder, Medical Director); Alexey Shagraev, PhD (Co-founder, CEO and CTO); Dr. Sofía Perea Pérez, MD, MSc (Medical Board); Aishani Shah, MD (Medical Board); Asya Zubkova, MS (Medical Board); Hanna Kurets, MD (Medical Board, Medical Advisor); Elina Nazarenko, MD (Medical Board); Victoria Derkova, MS (Medical Board). Page built Nov 8, 2026. More from Lovi: https://lovi.care/skincare/llms.txt ## This page in other countries - United States: https://lovi.care/skincare/ingredients/superoxide-dismutase - United Kingdom: https://lovi.care/skincare/uk/ingredients/superoxide-dismutase - Ireland: https://lovi.care/skincare/ie/ingredients/superoxide-dismutase - Germany: https://lovi.care/skincare/de/ingredients/superoxide-dismutase - France: https://lovi.care/skincare/fr/ingredients/superoxide-dismutase - Italy: https://lovi.care/skincare/it/ingredients/superoxide-dismutase - Netherlands: https://lovi.care/skincare/nl/ingredients/superoxide-dismutase - Spain: https://lovi.care/skincare/es/ingredients/superoxide-dismutase - Canada: https://lovi.care/skincare/ca/ingredients/superoxide-dismutase - Australia: https://lovi.care/skincare/au/ingredients/superoxide-dismutase - Singapore: https://lovi.care/skincare/sg/ingredients/superoxide-dismutase - Saudi Arabia: https://lovi.care/skincare/sa/ingredients/superoxide-dismutase - United Arab Emirates: https://lovi.care/skincare/ae/ingredients/superoxide-dismutase (this page)