Retinol and salicylic acid
Keep them apart
Use retinol and salicylic acid on alternate nights, because combining them causes severe dryness and irritation. Both ingredients speed up skin cell shedding, which can easily strip the skin barrier and cause redness or peeling when used together. To fix this, use a lower concentration or space them out over more nights.
Photocarcinogenesis study of glycolic acid and salicylic acid (CAS Nos. 79-14-1 and 69-72-7) in SKH-1 mice (simulated solar light and topical application study)Novel retinoid ester in combination with salicylic acid for the treatment of acne
Retinol products
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CeraVe
Resurfacing Retinol Serum
AED 60.50
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RoC
Retinol Correxion Deep Wrinkle Night Cream
AED 129.48
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Paula's Choice
1% Retinol Treatment
AED 255.32
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RoC
Retinol Correxion Line Smoothing Eye Cream
AED 90.00
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Good Molecules
Gentle Retinol Cream
AED 40.82
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La Roche-Posay
Retinol B3 Serum
AED 142.25
- DRMTLGY Retinol Body Lotion
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RoC
Retinol Correxion Deep Wrinkle Serum
AED 71.31
-
CeraVe
Skin Renewing Retinol Serum
AED 60.50
-
Olay
Regenerist Retinol 24 Night Moisturizer
AED 84.00
- cocokind Retinol Body Cream
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Neutrogena
Rapid Wrinkle Repair Regenerating Cream
AED 132.96
Salicylic acid products
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Paula's Choice
Skin Perfecting 2% BHA Liquid Exfoliant
AED 60.00
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Medicube
Zero Pore Pad
AED 41.99
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CeraVe
Renewing SA Cleanser
AED 51.95
-
Dermalogica
Daily Microfoliant
AED 101.09
- The Ordinary Salicylic Acid 2% Solution
-
Mario Badescu
Drying Lotion
AED 81.50
- La Roche-Posay Effaclar Medicated Gel Cleanser
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The Ordinary
AHA 30% + BHA 2% Peeling Solution
AED 42.60
-
Paula's Choice
10% Azelaic Acid Booster
AED 210.00
- CeraVe SA Lotion for Rough & Bumpy Skin
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COSRX
BHA Blackhead Power Liquid
AED 68.00
-
Hero Cosmetics
Mighty Patch
AED 40.42
Questions and answers
Can you use retinol and salicylic acid together?
Keep retinol and salicylic acid apart because layering them may cause over-exfoliation and irritation. Instead, alternate them by using salicylic acid in the morning or every other night, and apply your retinoid on alternate evenings.
Which goes first, retinol or salicylic acid?
Keep retinol and salicylic acid apart by using them on alternate evenings or separating them into different routines to avoid over-exfoliation and irritation.
Are retinol and salicylic acid good for sensitive skin?
No, retinol and salicylic acid should be kept apart in a skincare routine because combining them may cause over-exfoliation, irritation, or peeling on sensitive skin. You can use them safely by alternating evenings or using a moisturizer in between.
Research on retinol and salicylic acid
Molecular basis of retinol anti-ageing properties in naturally aged human skin in vivo
Encapsulation and controlled release of retinol from silicone particles for topical delivery
Behind this pairing advice
Lovi checks every pairing with brand-independent rules our dermatologists and cosmetic chemists build and review, and personalizes every pick with AI trained on the real results of millions of users. Lovi trains its fit score models on a proprietary dataset built from more than 10,000 expert-labeled products and more than 100,000 simulated examples, following an internally consistent methodology presented at Cosmoprof, AMWC, and Skin of Color Update.
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Elina Nazarenko, MD
Medical Board
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Victoria Derkova, MS
Medical Board
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