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Mandelic acid and collagen peptide

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Mandelic acid and collagen peptide: keep them apart

Keep them apart

Use mandelic acid and collagen peptide at different times of day, applying the acid first, because the acid breaks down the peptide. The acid is too acidic for the peptide, which makes the peptide stop working and gives you less results. You can fix this by using the acid in the morning and the peptide at night, or by waiting longer between applying them.

Mandelic acid products

Collagen peptide products

Questions and answers

Can you use mandelic acid and collagen peptide together?

No, you should keep mandelic acid and collagen peptide apart in your routine. The low pH of mandelic acid destabilizes peptide bonds and may reduce their effectiveness.

Which goes first, mandelic acid or collagen peptide?

Keep mandelic acid and collagen peptide apart in your routine, using them in separate steps or at different times of day such as AM and PM. The low pH of mandelic acid destabilizes peptide bonds and may reduce the bioactivity of collagen peptide.

Are mandelic acid and collagen peptide good for sensitive skin?

Mandelic acid and collagen peptide should be kept apart in your routine, as low-pH acids can destabilize peptides and irritate sensitive skin. You can easily use them in separate steps or alternate routines to get the benefits of both safely.

Research on mandelic acid and collagen peptide

Behind this pairing advice

Lovi checks every pairing with brand-independent rules our dermatologists and cosmetic chemists build and review, and personalizes every pick with AI trained on the real results of millions of users. Lovi trains its fit score models on a proprietary dataset built from more than 10,000 expert-labeled products and more than 100,000 simulated examples, following an internally consistent methodology presented at Cosmoprof, AMWC, and Skin of Color Update.

  • Nadia Kapleva, MS

    Nadia Kapleva, MS

    Co-founder, Medical Director

    Cosmetic chemist, cosmetologist, aesthetic products developer

  • Alexey Shagraev, PhD

    Alexey Shagraev, PhD

    Co-founder, CEO and CTO

    PhD in computer science, 3x US patent holder, ex-Google, ex-Yandex

  • Dr. Sof铆a Perea P茅rez, MD, MSc

    Dr. Sof铆a Perea P茅rez, MD, MSc

    Medical Board

    Aesthetic medicine practitioner, MSc in Longevity and Anti-Aging Medicine

  • Aishani Shah, MD

    Aishani Shah, MD

    Medical Board

    Specialist dermatologist, MBBS, MD, IFAAD

  • Asya Zubkova, MS

    Asya Zubkova, MS

    Medical Board

    Cosmetic chemist, SCS, IFSCC member

  • Hanna Kurets, MD

    Hanna Kurets, MD

    Medical Board, Medical Advisor

    Dermatology MD

  • Elina Nazarenko, MD

    Elina Nazarenko, MD

    Medical Board

    Dermatology and diagnostic consultant

  • Victoria Derkova, MS

    Victoria Derkova, MS

    Medical Board

    Cosmetic chemist, cosmetic development technologist

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