# Gluconolactone and hyaluronic acid

Page: https://lovi.care/skincare/ae/ingredients/gluconolactone-and-hyaluronic-acid

The Lovi Fit is the same in every country; only the stores and prices differ, and the ones here are for the United Arab Emirates.

Work well together

Use them together in the same routine, applying the mild acid first and then the [hyaluronic acid](https://lovi.care/skincare/ae/ingredients/hyaluronic-acid), because they help each other hydrate and renew the skin. [Gluconolactone](https://lovi.care/skincare/ae/ingredients/gluconolactone) gently removes dead skin cells so hyaluronic acid can sink in deeper for extra moisture. If your skin feels sensitive, you can use a gentler strength or apply them on alternate days.

- [All about gluconolactone](https://lovi.care/skincare/ae/ingredients/gluconolactone)
- [All about hyaluronic acid](https://lovi.care/skincare/ae/ingredients/hyaluronic-acid)

### [Gluconolactone](https://lovi.care/skincare/ae/ingredients/gluconolactone) products

- [CeraVe Blemish Control Cleanser](https://lovi.care/skincare/ae/p/cerave/blemish-control-cleanser/for/oily-acne-prone-skin) — Superior fit — [AED 54.95 at Amazon](https://www.amazon.ae/dp/B0B7RQ46LD?tag=lovi00-21&linkCode=osi&th=1&psc=1)
- [BYOMA Clarifying Serum](https://lovi.care/skincare/ae/p/byoma/clarifying-serum/for/dry-skin) — High fit — [AED 64.29 at Amazon](https://www.amazon.ae/dp/B0C7C8BZLM?tag=lovi00-21&linkCode=osi&th=1&psc=1)
- [EADEM Cashmere Peel](https://lovi.care/skincare/ae/p/eadem/cashmere-peel/for/oily-skin) — Average fit
- [The INKEY List PHA Toner](https://lovi.care/skincare/ae/p/the-inkey-list/pha-toner/for/acne-prone-skin) — Superior fit — [AED 81.68 at Amazon](https://www.amazon.ae/dp/B09NB35HJB?tag=lovi00-21&linkCode=osi&th=1&psc=1)
- [Kiehl's Hydro-Plumping Serum Concentrate](https://lovi.care/skincare/ae/p/kiehl-s/hydro-plumping-serum-concentrate/for/dry-skin) — Superior fit — [AED 325.93 at Amazon](https://www.amazon.ae/dp/B00XDIHDDS?tag=lovi00-21&linkCode=osi&th=1&psc=1)
- [StriVectin Daily Reveal Exfoliating Pads](https://lovi.care/skincare/ae/p/strivectin/daily-reveal-exfoliating-pads/for/oily-skin) — Average fit — [AED 177.43 at Amazon](https://www.amazon.ae/dp/B089TPYFX3?tag=lovi00-21&linkCode=osi&th=1&psc=1)
- [Hero Cosmetics Pore Release Blackhead Clearing Solution](https://lovi.care/skincare/ae/p/hero-cosmetics/pore-release-blackhead-clearing-solution/for/combination-skin) — Superior fit
- [Some By Mi AHA-BHA-PHA 30 Days Miracle Acne Clear Foam](https://lovi.care/skincare/ae/p/some-by-mi/aha-bha-pha-30-days-miracle-acne-clear-foam/for/oily-acne-prone-skin) — High fit — [AED 111.68 at Amazon](https://www.amazon.ae/dp/B0DY78ZDPS?tag=lovi00-21&linkCode=osi&th=1&psc=1)
- [OLEHENRIKSEN Truth Juice Daily Cleanser](https://lovi.care/skincare/ae/p/olehenriksen/truth-juice-daily-cleanser/for/oily-acne-prone-skin) — High fit
- [Face Reality sal-C toner](https://lovi.care/skincare/ae/p/face-reality/sal-c-toner/for/oily-acne-prone-skin) — High fit
- [Farmacy Brighten Up 3% TXA](https://lovi.care/skincare/ae/p/farmacy/brighten-up-3-txa/for/acne-prone-skin) — Average fit — [AED 161.22 at Amazon](https://www.amazon.ae/dp/B0BZTDBLJY?tag=lovi00-21&linkCode=osi&th=1&psc=1)
- [Neutrogena Bright Boost Gel Cream](https://lovi.care/skincare/ae/p/neutrogena/bright-boost-gel-cream/for/acne-prone-skin) — High fit

### [Hyaluronic acid](https://lovi.care/skincare/ae/ingredients/hyaluronic-acid) products

- [CeraVe Moisturising Cream](https://lovi.care/skincare/ae/p/cerave/moisturising-cream/for/dry-sensitive-skin) — Superior fit — [AED 61.33 at Amazon](https://www.amazon.ae/dp/B07CHPWFXK?tag=lovi00-21&linkCode=osi&th=1&psc=1)
- [CeraVe Hydrating Facial Cleanser](https://lovi.care/skincare/ae/p/cerave/hydrating-facial-cleanser/for/dry-skin) — Superior fit — [AED 32.95 at Amazon](https://www.amazon.ae/dp/B07C5R51Q9?tag=lovi00-21&linkCode=osi&th=1&psc=1)
- [Rhode Glazing Milk](https://lovi.care/skincare/ae/p/rhode/glazing-milk/for/dry-skin) — Superior fit — [AED 248.49 at Amazon](https://www.amazon.ae/dp/B0D388ZWLF?tag=lovi00-21&linkCode=osi&th=1&psc=1)
- [CeraVe Foaming Facial Cleanser](https://lovi.care/skincare/ae/p/cerave/foaming-facial-cleanser/for/oily-skin) — Superior fit — [AED 49.95 at Amazon](https://www.amazon.ae/dp/B07C5XD33D?tag=lovi00-21&linkCode=osi&th=1&psc=1)
- [Vanicream Daily Facial Moisturizer](https://lovi.care/skincare/ae/p/vanicream/daily-facial-moisturizer/for/dry-skin) — Superior fit — [AED 150.00 at Amazon](https://www.amazon.ae/dp/B0D96W24CX?tag=lovi00-21&linkCode=osi&th=1&psc=1)
- [COSRX Advanced Snail 96 Mucin Power Essence](https://lovi.care/skincare/ae/p/cosrx/advanced-snail-96-mucin-power-essence/for/dry-skin) — Superior fit — [AED 29.35 at Amazon](https://www.amazon.ae/dp/B00PBX3L7K?tag=lovi00-21&linkCode=osi&th=1&psc=1)
- [Dr. Althea 345 Relief Cream](https://lovi.care/skincare/ae/p/dr-althea/345-relief-cream/for/acne-prone-skin) — Superior fit — [AED 54.05 at Amazon](https://www.amazon.ae/dp/B07PK2P2XB?tag=lovi00-21&linkCode=osi&th=1&psc=1)
- [Biodance Bio-Collagen Real Deep Mask](https://lovi.care/skincare/ae/p/biodance/bio-collagen-real-deep-mask/for/mature-skin) — Superior fit — [AED 35.15 at Amazon](https://www.amazon.ae/dp/B0B2RM68G2?tag=lovi00-21&linkCode=osi&th=1&psc=1)
- [Neutrogena Hydro Boost Water Gel](https://lovi.care/skincare/ae/p/neutrogena/hydro-boost-water-gel/for/sensitive-skin) — Average fit — [AED 41.49 at Amazon](https://www.amazon.ae/dp/B0DHZNLPTL?tag=lovi00-21&linkCode=osi&th=1&psc=1)
- [Olay Regenerist Micro-Sculpting Cream](https://lovi.care/skincare/ae/p/olay/regenerist-micro-sculpting-cream/for/mature-skin) — Superior fit — [AED 88.09 at Amazon](https://www.amazon.ae/dp/B078LSV2RL?tag=lovi00-21&linkCode=osi&th=1&psc=1)
- [CeraVe Daily Moisturizing Lotion](https://lovi.care/skincare/ae/p/cerave/daily-moisturizing-lotion/for/dry-skin) — Superior fit — [AED 40.41 at Amazon](https://www.amazon.ae/dp/B07CG2TD9F?tag=lovi00-21&linkCode=osi&th=1&psc=1)
- [CeraVe Healing Ointment](https://lovi.care/skincare/ae/p/cerave/healing-ointment/for/dry-skin) — High fit

## Questions and answers

### Can you use gluconolactone and hyaluronic acid together?

Yes, [gluconolactone](https://lovi.care/skincare/ae/ingredients/gluconolactone) and [hyaluronic acid](https://lovi.care/skincare/ae/ingredients/hyaluronic-acid) work well together to promote gentle exfoliation with hydration support, and you can find both in products like CLIV PHA Mild Enzyme Powder, COSRX Hydrium Triple Hyaluronic Moisture Ampoule, SKIN1004 Madagascar [Centella](https://lovi.care/skincare/ae/ingredients/centella-asiatica) Toning Toner, and Augustinus Bader The Exfoliating Toner.

### Which goes first, gluconolactone or hyaluronic acid?

Gluconolactone and hyaluronic acid work well together, promoting gentle exfoliation with daily hydration support. You can find both ingredients in products like CLIV PHA Mild Enzyme Powder, COSRX Hydrium Triple Hyaluronic Moisture Ampoule, SKIN1004 Madagascar Centella Toning Toner, and Augustinus Bader The Exfoliating Toner.

### Are gluconolactone and hyaluronic acid good for sensitive skin?

Gluconolactone and hyaluronic acid work well together to promote gentle exfoliation with hydration support, making them a beneficial choice for normal to dry skin. Products like CLIV PHA Mild Enzyme Powder, COSRX Hydrium Triple Hyaluronic Moisture Ampoule, SKIN1004 Madagascar Centella Toning Toner, and Augustinus Bader The Exfoliating Toner combine these ingredients.

## Research on gluconolactone and hyaluronic acid

- [Hyaluronic acid, a promising skin rejuvenating biomedicine: A review of recent updates and pre-clinical and clinical investigations on cosmetic and nutricosmetic effects](https://pubmed.ncbi.nlm.nih.gov/30287361/) Hyaluronic acid · International Journal of Biological Macromolecules, 2018
- [Hyaluronic acid and wound healing](https://pubmed.ncbi.nlm.nih.gov/25877441/) Hyaluronic acid · Journal of Pharmacy & Pharmaceutical Sciences, 2015
- [Skin delivery of epigallocatechin-3-gallate (EGCG) and hyaluronic acid loaded nano-transfersomes for antioxidant and anti-aging effects in UV radiation induced skin damage](https://pubmed.ncbi.nlm.nih.gov/28155509/) Hyaluronic acid · Drug Delivery, 2017
- [Benefits of topical hyaluronic acid for skin quality and signs of skin aging: From literature review to clinical evidence](https://pubmed.ncbi.nlm.nih.gov/36200921/) Hyaluronic acid · Dermatologic Therapy, 2022
- [The efficacy of glycolic acid, salicylic acid, gluconolactone, and licochalcone A combined with 0.1% adapalene vs adapalene monotherapy in mild-to-moderate acne vulgaris: a double-blinded within-person comparative study](https://pubmed.ncbi.nlm.nih.gov/30858720/) Gluconolactone · Clinical, Cosmetic and Investigational Dermatology, 2019
- [A comparative study of gluconolactone versus benzoyl peroxide in the treatment of acne](https://pubmed.ncbi.nlm.nih.gov/1303072/) Gluconolactone · The Australasian Journal of Dermatology, 1992
- [Liposome, gel and lipogelosome formulations containing sodium hyaluronate](https://pubmed.ncbi.nlm.nih.gov/24724824/) Hyaluronic acid · Journal of Liposome Research, 2014
- [Botulinum toxin injection as a single or combined treatment with non-cross-linked high molecular weight and low molecular weight hyaluronic acid gel for neck rejuvenation: A randomized clinical trial](https://pubmed.ncbi.nlm.nih.gov/35775872/) Hyaluronic acid · Dermatologic Therapy, 2022
- [Efficacy and Tolerability of Stable Hybrid Cooperative Complexes of High- and Low-Molecular Weight Hyaluronic Acid in Asian Patients: An Open-Label Study](https://pubmed.ncbi.nlm.nih.gov/40921777/) Hyaluronic acid · Aesthetic Plastic Surgery, 2026
- [Nanocomplex of quaternized cyclodextrin grafted chitosan and hyaluronic acid for a skin delivery](https://pubmed.ncbi.nlm.nih.gov/36279763/) Hyaluronic acid · Colloids and Surfaces. B, Biointerfaces, 2022
- [Split-face evaluation: Gluconolactone plus oxybrasion versus gluconolactone plus microneedling. The effects on skin parameters](https://pubmed.ncbi.nlm.nih.gov/37357656/) Gluconolactone · Skin Research and Technology, 2023

## Other combinations

- Depends on the strength: [Niacinamide and gluconolactone](https://lovi.care/skincare/ae/ingredients/niacinamide-and-gluconolactone)
- Work well together: [Acetyl hexapeptide-3 and hyaluronic acid](https://lovi.care/skincare/ae/ingredients/acetyl-hexapeptide-3-and-hyaluronic-acid)
- Work well together: [Bio-placenta peptides and hyaluronic acid](https://lovi.care/skincare/ae/ingredients/bio-placenta-peptides-and-hyaluronic-acid)
- Work well together: [Hyaluronic acid and collagen peptide](https://lovi.care/skincare/ae/ingredients/hyaluronic-acid-and-collagen-peptide)
- Work well together: [Hyaluronic acid and copper peptide](https://lovi.care/skincare/ae/ingredients/hyaluronic-acid-and-copper-peptide)
- Work well together: [Hexapeptide and hyaluronic acid](https://lovi.care/skincare/ae/ingredients/hexapeptide-and-hyaluronic-acid)
- Work well together: [Hyaluronic acid and hexapeptide-9](https://lovi.care/skincare/ae/ingredients/hyaluronic-acid-and-hexapeptide-9)
- Work well together: [Hyaluronic acid and palmitoyl pentapeptide-4](https://lovi.care/skincare/ae/ingredients/hyaluronic-acid-and-palmitoyl-pentapeptide-4)
- Work well together: [Hyaluronic acid and palmitoyl tripeptide-1](https://lovi.care/skincare/ae/ingredients/hyaluronic-acid-and-palmitoyl-tripeptide-1)
- Work well together: [Hyaluronic acid and peptide-rich plasma](https://lovi.care/skincare/ae/ingredients/hyaluronic-acid-and-peptide-rich-plasma)
- Work well together: [Hyaluronic acid and triple peptide blend](https://lovi.care/skincare/ae/ingredients/hyaluronic-acid-and-triple-peptide-blend)
- Work well together: [Hyaluronic acid and lactobionic acid](https://lovi.care/skincare/ae/ingredients/hyaluronic-acid-and-lactobionic-acid)
- Work well together: [Hyaluronic acid and ascorbyl glucoside](https://lovi.care/skincare/ae/ingredients/hyaluronic-acid-and-ascorbyl-glucoside)
- Work well together: [Coenzyme Q10 and hyaluronic acid](https://lovi.care/skincare/ae/ingredients/coenzyme-q10-and-hyaluronic-acid)
- Work well together: [Vitamin E and hyaluronic acid](https://lovi.care/skincare/ae/ingredients/vitamin-e-and-hyaluronic-acid)
- Depends on the strength: [AHA blend glycolic and citric acids and hyaluronic acid](https://lovi.care/skincare/ae/ingredients/aha-blend-glycolic-and-citric-acids-and-hyaluronic-acid)
- Depends on the strength: [Hyaluronic acid and citric acid](https://lovi.care/skincare/ae/ingredients/hyaluronic-acid-and-citric-acid)
- Depends on the strength: [Glycolic acid and hyaluronic acid](https://lovi.care/skincare/ae/ingredients/glycolic-acid-and-hyaluronic-acid)
- Depends on the strength: [Lactic acid and hyaluronic acid](https://lovi.care/skincare/ae/ingredients/lactic-acid-and-hyaluronic-acid)
- Depends on the strength: [Mandelic acid and hyaluronic acid](https://lovi.care/skincare/ae/ingredients/mandelic-acid-and-hyaluronic-acid)
- Work well together: [Hyaluronic acid and tri-ceramide complex](https://lovi.care/skincare/ae/ingredients/hyaluronic-acid-and-tri-ceramide-complex)
- Keep them apart: [Azelaic acid and hyaluronic acid](https://lovi.care/skincare/ae/ingredients/azelaic-acid-and-hyaluronic-acid)
- Keep them apart: [Salicylic acid and hyaluronic acid](https://lovi.care/skincare/ae/ingredients/salicylic-acid-and-hyaluronic-acid)
- Work well together: [Niacinamide and hyaluronic acid](https://lovi.care/skincare/ae/ingredients/niacinamide-and-hyaluronic-acid)
- Keep them apart: [Hyaluronic acid and bergamot oil](https://lovi.care/skincare/ae/ingredients/hyaluronic-acid-and-bergamot-oil)
- Keep them apart: [Hyaluronic acid and camphor oil](https://lovi.care/skincare/ae/ingredients/hyaluronic-acid-and-camphor-oil)
- Keep them apart: [Hyaluronic acid and chamomile oil](https://lovi.care/skincare/ae/ingredients/hyaluronic-acid-and-chamomile-oil)
- Keep them apart: [Hyaluronic acid and clove leaf oil](https://lovi.care/skincare/ae/ingredients/hyaluronic-acid-and-clove-leaf-oil)
- Keep them apart: [Hyaluronic acid and eucalyptus oil](https://lovi.care/skincare/ae/ingredients/hyaluronic-acid-and-eucalyptus-oil)
- Keep them apart: [Hyaluronic acid and geranium oil](https://lovi.care/skincare/ae/ingredients/hyaluronic-acid-and-geranium-oil)
- Keep them apart: [Hyaluronic acid and grapefruit peel oil](https://lovi.care/skincare/ae/ingredients/hyaluronic-acid-and-grapefruit-peel-oil)
- Keep them apart: [Lavender oil and hyaluronic acid](https://lovi.care/skincare/ae/ingredients/lavender-oil-and-hyaluronic-acid)
- Keep them apart: [Hyaluronic acid and lemon oil](https://lovi.care/skincare/ae/ingredients/hyaluronic-acid-and-lemon-oil)
- Keep them apart: [Hyaluronic acid and orange oil](https://lovi.care/skincare/ae/ingredients/hyaluronic-acid-and-orange-oil)
- Keep them apart: [Hyaluronic acid and palmarosa oil](https://lovi.care/skincare/ae/ingredients/hyaluronic-acid-and-palmarosa-oil)
- Keep them apart: [Hyaluronic acid and peppermint oil](https://lovi.care/skincare/ae/ingredients/hyaluronic-acid-and-peppermint-oil)
- Keep them apart: [Hyaluronic acid and rose oil](https://lovi.care/skincare/ae/ingredients/hyaluronic-acid-and-rose-oil)
- Keep them apart: [Hyaluronic acid and rosewood oil](https://lovi.care/skincare/ae/ingredients/hyaluronic-acid-and-rosewood-oil)
- Keep them apart: [Hyaluronic acid and sandalwood oil](https://lovi.care/skincare/ae/ingredients/hyaluronic-acid-and-sandalwood-oil)
- Keep them apart: [Tea tree oil and hyaluronic acid](https://lovi.care/skincare/ae/ingredients/tea-tree-oil-and-hyaluronic-acid)
- Keep them apart: [Hyaluronic acid and thyme oil](https://lovi.care/skincare/ae/ingredients/hyaluronic-acid-and-thyme-oil)
- Keep them apart: [Hyaluronic acid and wild mint oil](https://lovi.care/skincare/ae/ingredients/hyaluronic-acid-and-wild-mint-oil)
- Work well together: [AHA blend glycolic and citric acids and gluconolactone](https://lovi.care/skincare/ae/ingredients/aha-blend-glycolic-and-citric-acids-and-gluconolactone)
- Work well together: [Gluconolactone and citric acid](https://lovi.care/skincare/ae/ingredients/gluconolactone-and-citric-acid)
- Work well together: [Glycolic acid and gluconolactone](https://lovi.care/skincare/ae/ingredients/glycolic-acid-and-gluconolactone)
- Work well together: [Lactic acid and gluconolactone](https://lovi.care/skincare/ae/ingredients/lactic-acid-and-gluconolactone)
- Work well together: [Mandelic acid and gluconolactone](https://lovi.care/skincare/ae/ingredients/mandelic-acid-and-gluconolactone)
- Work well together: [Hyaluronic acid and cholesterol](https://lovi.care/skincare/ae/ingredients/hyaluronic-acid-and-cholesterol)
- Work well together: [Hyaluronic acid and lauric acid](https://lovi.care/skincare/ae/ingredients/hyaluronic-acid-and-lauric-acid)
- Work well together: [Linoleic acid and hyaluronic acid](https://lovi.care/skincare/ae/ingredients/linoleic-acid-and-hyaluronic-acid)
- Work well together: [Vitamin C and gluconolactone](https://lovi.care/skincare/ae/ingredients/vitamin-c-and-gluconolactone)
- Keep them apart: [Hyaluronic acid and isopropyl alcohol](https://lovi.care/skincare/ae/ingredients/hyaluronic-acid-and-isopropyl-alcohol)
- Work well together: [Salicylic acid and gluconolactone](https://lovi.care/skincare/ae/ingredients/salicylic-acid-and-gluconolactone)
- Work well together: [Arginine and hyaluronic acid](https://lovi.care/skincare/ae/ingredients/arginine-and-hyaluronic-acid)
- Work well together: [Hyaluronic acid and GABA](https://lovi.care/skincare/ae/ingredients/hyaluronic-acid-and-gaba)
- Work well together: [Silk amino acids and hyaluronic acid](https://lovi.care/skincare/ae/ingredients/silk-amino-acids-and-hyaluronic-acid)
- Work well together: [Taurine and hyaluronic acid](https://lovi.care/skincare/ae/ingredients/taurine-and-hyaluronic-acid)
- Work well together: [Hyaluronic acid and theanine](https://lovi.care/skincare/ae/ingredients/hyaluronic-acid-and-theanine)
- Work well together: [Panthenol and hyaluronic acid](https://lovi.care/skincare/ae/ingredients/panthenol-and-hyaluronic-acid)
- Work well together: [Vitamin C and hyaluronic acid](https://lovi.care/skincare/ae/ingredients/vitamin-c-and-hyaluronic-acid)

## About the Lovi Fit

Lovi: Unbiased, science-based skincare AI trained on real user outcomes.

Lovi checks every pairing with brand-independent rules its dermatologists and cosmetic chemists build and review, and personalizes every pick with AI trained on the real results of millions of users. Lovi trains its fit score models on a proprietary dataset built from more than 10,000 expert-labeled products and more than 100,000 simulated examples, following an internally consistent methodology presented at Cosmoprof, AMWC, and Skin of Color Update. Levels from best to worst: Superior, High, Average, Low, Caution, Warning.

Behind this pairing advice: Nadia Kapleva, MS (Co-founder, Medical Director); Alexey Shagraev, PhD (Co-founder, CEO and CTO); Dr. Sofía Perea Pérez, MD, MSc (Medical Board); Aishani Shah, MD (Medical Board); Asya Zubkova, MS (Medical Board); Hanna Kurets, MD (Medical Board, Medical Advisor); Elina Nazarenko, MD (Medical Board); Victoria Derkova, MS (Medical Board).

Page built Nov 8, 2026.

More from Lovi: https://lovi.care/skincare/llms.txt

## This page in other countries

- United States: https://lovi.care/skincare/ingredients/gluconolactone-and-hyaluronic-acid
- United Kingdom: https://lovi.care/skincare/uk/ingredients/gluconolactone-and-hyaluronic-acid
- Ireland: https://lovi.care/skincare/ie/ingredients/gluconolactone-and-hyaluronic-acid
- Germany: https://lovi.care/skincare/de/ingredients/gluconolactone-and-hyaluronic-acid
- France: https://lovi.care/skincare/fr/ingredients/gluconolactone-and-hyaluronic-acid
- Italy: https://lovi.care/skincare/it/ingredients/gluconolactone-and-hyaluronic-acid
- Netherlands: https://lovi.care/skincare/nl/ingredients/gluconolactone-and-hyaluronic-acid
- Spain: https://lovi.care/skincare/es/ingredients/gluconolactone-and-hyaluronic-acid
- Canada: https://lovi.care/skincare/ca/ingredients/gluconolactone-and-hyaluronic-acid
- Australia: https://lovi.care/skincare/au/ingredients/gluconolactone-and-hyaluronic-acid
- Singapore: https://lovi.care/skincare/sg/ingredients/gluconolactone-and-hyaluronic-acid
- Saudi Arabia: https://lovi.care/skincare/sa/ingredients/gluconolactone-and-hyaluronic-acid
- United Arab Emirates: https://lovi.care/skincare/ae/ingredients/gluconolactone-and-hyaluronic-acid (this page)
