# Acetyl hexapeptide-3 and hyaluronic acid Page: https://lovi.care/skincare/ae/ingredients/acetyl-hexapeptide-3-and-hyaluronic-acid The Lovi Fit is the same in every country; only the stores and prices differ, and the ones here are for the United Arab Emirates. Work well together Apply the [hyaluronic acid](https://lovi.care/skincare/ae/ingredients/hyaluronic-acid) first and the peptide product right after, because they work wonderfully when used in the same routine. The hyaluronic acid creates a moisture-rich base that helps the peptides firm the skin and boost elasticity much better. You do not need to change anything since this combination is very gentle and effective. [Effects of water activity and low molecular weight humectants on skin permeability and hydration dynamics - a double-blind, randomized and controlled study](https://pubmed.ncbi.nlm.nih.gov/24786192/) [The efficiency of humectants as skin moisturizers in the presence of oil](https://pubmed.ncbi.nlm.nih.gov/11301638/) - [All about acetyl hexapeptide-3](https://lovi.care/skincare/ae/ingredients/acetyl-hexapeptide-3) - [All about hyaluronic acid](https://lovi.care/skincare/ae/ingredients/hyaluronic-acid) ### [Acetyl hexapeptide-3](https://lovi.care/skincare/ae/ingredients/acetyl-hexapeptide-3) products - [Medik8 Liquid Peptides](https://lovi.care/skincare/ae/p/medik8/liquid-peptides/for/oily-acne-prone-skin) — Average fit — [AED 469.66 at Amazon](https://www.amazon.ae/dp/B0DYV9VSDV?tag=lovi00-21&linkCode=osi&th=1&psc=1) - [The Ordinary Argireline Solution 10%](https://lovi.care/skincare/ae/p/the-ordinary/argireline-solution-10/for/mature-skin) — Average fit - [La Mer The Renewal Oil](https://lovi.care/skincare/ae/p/la-mer/the-renewal-oil/for/mature-skin) — High fit — [AED 1,286.50 at Amazon](https://www.amazon.ae/dp/B0163GAMI4?tag=lovi00-21&linkCode=osi&th=1&psc=1) - [The INKEY List Collagen Peptide Serum](https://lovi.care/skincare/ae/p/the-inkey-list/collagen-peptide-serum/for/dry-sensitive-skin) — High fit - [La Mer The Eye Concentrate](https://lovi.care/skincare/ae/p/la-mer/the-eye-concentrate/for/mature-skin) — High fit — [AED 794.35 at Amazon](https://www.amazon.ae/dp/B085614WX5?tag=lovi00-21&linkCode=osi&th=1&psc=1) - [NATURIUM Multi-Peptide Advanced Serum](https://lovi.care/skincare/ae/p/naturium/multi-peptide-advanced-serum/for/mature-skin) — High fit — [AED 98.82 at Amazon](https://www.amazon.ae/dp/B0CQTSM65J?tag=lovi00-21&linkCode=osi&th=1&psc=1) - [Perricone MD Cold Plasma Plus+](https://lovi.care/skincare/ae/p/perricone-md/cold-plasma-plus/for/mature-skin) — Average fit — [AED 240.55 at Amazon](https://www.amazon.ae/dp/B07CNXYFSD?tag=lovi00-21&linkCode=osi&th=1&psc=1) - [La Mer The Regenerating Serum](https://lovi.care/skincare/ae/p/la-mer/the-regenerating-serum/for/mature-skin) — High fit — [AED 2,015.00 at Amazon](https://www.amazon.ae/dp/B07X7NRNCY?tag=lovi00-21&linkCode=osi&th=1&psc=1) - [Estée Lauder Perfectionist Pro](https://lovi.care/skincare/ae/p/estee-lauder/perfectionist-pro/for/mature-skin) — Average fit - [Perricone MD Deep Crease Serum](https://lovi.care/skincare/ae/p/perricone-md/deep-crease-serum/for/dry-sensitive-skin) — High fit - [La Mer The Lifting Eye Serum](https://lovi.care/skincare/ae/p/la-mer/the-lifting-eye-serum/for/mature-skin) — High fit - [Origins Original Skin Renewal Serum](https://lovi.care/skincare/ae/p/origins/original-skin-renewal-serum/for/acne-prone-skin) — Average fit — [AED 335.00 at Amazon](https://www.amazon.ae/dp/B091B5VGS3?tag=lovi00-21&linkCode=osi&th=1&psc=1) ### [Hyaluronic acid](https://lovi.care/skincare/ae/ingredients/hyaluronic-acid) products - [CeraVe Moisturising Cream](https://lovi.care/skincare/ae/p/cerave/moisturising-cream/for/dry-sensitive-skin) — Superior fit — [AED 61.33 at Amazon](https://www.amazon.ae/dp/B07CHPWFXK?tag=lovi00-21&linkCode=osi&th=1&psc=1) - [CeraVe Hydrating Facial Cleanser](https://lovi.care/skincare/ae/p/cerave/hydrating-facial-cleanser/for/dry-skin) — Superior fit — [AED 32.95 at Amazon](https://www.amazon.ae/dp/B07C5R51Q9?tag=lovi00-21&linkCode=osi&th=1&psc=1) - [Rhode Glazing Milk](https://lovi.care/skincare/ae/p/rhode/glazing-milk/for/dry-skin) — Superior fit — [AED 248.49 at Amazon](https://www.amazon.ae/dp/B0D388ZWLF?tag=lovi00-21&linkCode=osi&th=1&psc=1) - [CeraVe Foaming Facial Cleanser](https://lovi.care/skincare/ae/p/cerave/foaming-facial-cleanser/for/oily-skin) — Superior fit — [AED 49.95 at Amazon](https://www.amazon.ae/dp/B07C5XD33D?tag=lovi00-21&linkCode=osi&th=1&psc=1) - [Vanicream Daily Facial Moisturizer](https://lovi.care/skincare/ae/p/vanicream/daily-facial-moisturizer/for/dry-skin) — Superior fit — [AED 150.00 at Amazon](https://www.amazon.ae/dp/B0D96W24CX?tag=lovi00-21&linkCode=osi&th=1&psc=1) - [COSRX Advanced Snail 96 Mucin Power Essence](https://lovi.care/skincare/ae/p/cosrx/advanced-snail-96-mucin-power-essence/for/dry-skin) — Superior fit — [AED 29.35 at Amazon](https://www.amazon.ae/dp/B00PBX3L7K?tag=lovi00-21&linkCode=osi&th=1&psc=1) - [Dr. Althea 345 Relief Cream](https://lovi.care/skincare/ae/p/dr-althea/345-relief-cream/for/acne-prone-skin) — Superior fit — [AED 54.05 at Amazon](https://www.amazon.ae/dp/B07PK2P2XB?tag=lovi00-21&linkCode=osi&th=1&psc=1) - [Biodance Bio-Collagen Real Deep Mask](https://lovi.care/skincare/ae/p/biodance/bio-collagen-real-deep-mask/for/mature-skin) — Superior fit — [AED 35.15 at Amazon](https://www.amazon.ae/dp/B0B2RM68G2?tag=lovi00-21&linkCode=osi&th=1&psc=1) - [Neutrogena Hydro Boost Water Gel](https://lovi.care/skincare/ae/p/neutrogena/hydro-boost-water-gel/for/sensitive-skin) — Average fit — [AED 41.49 at Amazon](https://www.amazon.ae/dp/B0DHZNLPTL?tag=lovi00-21&linkCode=osi&th=1&psc=1) - [Olay Regenerist Micro-Sculpting Cream](https://lovi.care/skincare/ae/p/olay/regenerist-micro-sculpting-cream/for/mature-skin) — Superior fit — [AED 88.09 at Amazon](https://www.amazon.ae/dp/B078LSV2RL?tag=lovi00-21&linkCode=osi&th=1&psc=1) - [CeraVe Daily Moisturizing Lotion](https://lovi.care/skincare/ae/p/cerave/daily-moisturizing-lotion/for/dry-skin) — Superior fit — [AED 40.41 at Amazon](https://www.amazon.ae/dp/B07CG2TD9F?tag=lovi00-21&linkCode=osi&th=1&psc=1) - [CeraVe Healing Ointment](https://lovi.care/skincare/ae/p/cerave/healing-ointment/for/dry-skin) — High fit ## Questions and answers ### Can you use acetyl hexapeptide-3 and hyaluronic acid together? Yes, you can use [acetyl hexapeptide-3](https://lovi.care/skincare/ae/ingredients/acetyl-hexapeptide-3) and [hyaluronic acid](https://lovi.care/skincare/ae/ingredients/hyaluronic-acid) together because they work well to improve hydration and elasticity, and you can find them combined in products like FRANKLY Closer [Serum](https://lovi.care/skincare/ae/ingredients/serum) and La Mer The Lifting and Firming Mask. Combining them helps provide a hydration scaffold while peptides support skin firmness. Lovi rates this combination as High. [Annals of Dermatology, 2019](https://pubmed.ncbi.nlm.nih.gov/33911590/) ### Which goes first, acetyl hexapeptide-3 or hyaluronic acid? Acetyl hexapeptide-3 and hyaluronic acid work well together and can be layered by applying a hydrating serum beneath your peptide product. This combination helps improve skin elasticity and hydration by providing a moisture scaffold while supporting [collagen](https://lovi.care/skincare/ae/ingredients/collagen) synthesis. [Annals of Dermatology, 2019](https://pubmed.ncbi.nlm.nih.gov/33911590/) ### Are acetyl hexapeptide-3 and hyaluronic acid good for sensitive skin? Acetyl hexapeptide-3 and hyaluronic acid work well together because hyaluronic acid provides a hydration scaffold while peptides trigger collagen synthesis, supporting barrier integrity. This combination helps improve elasticity and hydration for all skin types, including dry and mature skin, and can be found in products like Mediheal N.M.F Aquaring Gel Eyefill Patch and FRANKLY Closer Serum. [Annals of Dermatology, 2019](https://pubmed.ncbi.nlm.nih.gov/33911590/) [International Journal of Biological Macromolecules, 2018](https://pubmed.ncbi.nlm.nih.gov/30287361/) ## Research on acetyl hexapeptide-3 and hyaluronic acid - [Hyaluronic acid, a promising skin rejuvenating biomedicine: A review of recent updates and pre-clinical and clinical investigations on cosmetic and nutricosmetic effects](https://pubmed.ncbi.nlm.nih.gov/30287361/) Hyaluronic acid · International Journal of Biological Macromolecules, 2018 - [Hyaluronic acid and wound healing](https://pubmed.ncbi.nlm.nih.gov/25877441/) Hyaluronic acid · Journal of Pharmacy & Pharmaceutical Sciences, 2015 - [Skin delivery of epigallocatechin-3-gallate (EGCG) and hyaluronic acid loaded nano-transfersomes for antioxidant and anti-aging effects in UV radiation induced skin damage](https://pubmed.ncbi.nlm.nih.gov/28155509/) Hyaluronic acid · Drug Delivery, 2017 - [Benefits of topical hyaluronic acid for skin quality and signs of skin aging: From literature review to clinical evidence](https://pubmed.ncbi.nlm.nih.gov/36200921/) Hyaluronic acid · Dermatologic Therapy, 2022 - [The anti-wrinkle efficacy of argireline, a synthetic hexapeptide, in Chinese subjects: a randomized, placebo-controlled study](https://pubmed.ncbi.nlm.nih.gov/23417317/) Acetyl hexapeptide-3 · American Journal of Clinical Dermatology, 2013 - [Anti-Wrinkle Efficacy of Cross-Linked Hyaluronic Acid-Based Microneedle Patch with Acetyl Hexapeptide-8 and Epidermal Growth Factor on Korean Skin](https://pubmed.ncbi.nlm.nih.gov/33911590/) Acetyl hexapeptide-3 · Annals of Dermatology, 2019 - [Liposome, gel and lipogelosome formulations containing sodium hyaluronate](https://pubmed.ncbi.nlm.nih.gov/24724824/) Hyaluronic acid · Journal of Liposome Research, 2014 - [Botulinum toxin injection as a single or combined treatment with non-cross-linked high molecular weight and low molecular weight hyaluronic acid gel for neck rejuvenation: A randomized clinical trial](https://pubmed.ncbi.nlm.nih.gov/35775872/) Hyaluronic acid · Dermatologic Therapy, 2022 - [The efficacy study of the combination of tripeptide-10-citrulline and acetyl hexapeptide-3. A prospective, randomized controlled study](https://pubmed.ncbi.nlm.nih.gov/28150423/) Acetyl hexapeptide-3 · Journal of Cosmetic Dermatology, 2017 - [The anti wrinkle efficacy of synthetic hexapeptide (Argireline) in Chinese Subjects](https://pubmed.ncbi.nlm.nih.gov/23607739/) Acetyl hexapeptide-3 · Journal of Cosmetic and Laser Therapy, 2013 - [Efficacy and Tolerability of Stable Hybrid Cooperative Complexes of High- and Low-Molecular Weight Hyaluronic Acid in Asian Patients: An Open-Label Study](https://pubmed.ncbi.nlm.nih.gov/40921777/) Hyaluronic acid · Aesthetic Plastic Surgery, 2026 - [Nanocomplex of quaternized cyclodextrin grafted chitosan and hyaluronic acid for a skin delivery](https://pubmed.ncbi.nlm.nih.gov/36279763/) Hyaluronic acid · Colloids and Surfaces. B, Biointerfaces, 2022 ## Other combinations - Keep them apart: [Adapalene and acetyl hexapeptide-3](https://lovi.care/skincare/ae/ingredients/adapalene-and-acetyl-hexapeptide-3) - Keep them apart: [Acetyl hexapeptide-3 and granactive retinoid](https://lovi.care/skincare/ae/ingredients/acetyl-hexapeptide-3-and-granactive-retinoid) - Keep them apart: [Acetyl hexapeptide-3 and hydroxypinacolone retinoate](https://lovi.care/skincare/ae/ingredients/acetyl-hexapeptide-3-and-hydroxypinacolone-retinoate) - Keep them apart: [Pro-retinol and acetyl hexapeptide-3](https://lovi.care/skincare/ae/ingredients/pro-retinol-and-acetyl-hexapeptide-3) - Keep them apart: [Retinal and acetyl hexapeptide-3](https://lovi.care/skincare/ae/ingredients/retinal-and-acetyl-hexapeptide-3) - Keep them apart: [Acetyl hexapeptide-3 and retinoid blend](https://lovi.care/skincare/ae/ingredients/acetyl-hexapeptide-3-and-retinoid-blend) - Depends on the strength: [Retinol and acetyl hexapeptide-3](https://lovi.care/skincare/ae/ingredients/retinol-and-acetyl-hexapeptide-3) - Keep them apart: [Tretinoin and acetyl hexapeptide-3](https://lovi.care/skincare/ae/ingredients/tretinoin-and-acetyl-hexapeptide-3) - Keep them apart: [Vitamin A and acetyl hexapeptide-3](https://lovi.care/skincare/ae/ingredients/vitamin-a-and-acetyl-hexapeptide-3) - Work well together: [Liposome and acetyl hexapeptide-3](https://lovi.care/skincare/ae/ingredients/liposome-and-acetyl-hexapeptide-3) - Work well together: [Acetyl hexapeptide-3 and microcapsule](https://lovi.care/skincare/ae/ingredients/acetyl-hexapeptide-3-and-microcapsule) - Depends on the strength: [Vitamin C and acetyl hexapeptide-3](https://lovi.care/skincare/ae/ingredients/vitamin-c-and-acetyl-hexapeptide-3) - Work well together: [Acetyl hexapeptide-3 and betaine](https://lovi.care/skincare/ae/ingredients/acetyl-hexapeptide-3-and-betaine) - Work well together: [Glycerin and acetyl hexapeptide-3](https://lovi.care/skincare/ae/ingredients/glycerin-and-acetyl-hexapeptide-3) - Work well together: [Bio-placenta peptides and hyaluronic acid](https://lovi.care/skincare/ae/ingredients/bio-placenta-peptides-and-hyaluronic-acid) - Work well together: [Hyaluronic acid and collagen peptide](https://lovi.care/skincare/ae/ingredients/hyaluronic-acid-and-collagen-peptide) - Work well together: [Hyaluronic acid and copper peptide](https://lovi.care/skincare/ae/ingredients/hyaluronic-acid-and-copper-peptide) - Work well together: [Hexapeptide and hyaluronic acid](https://lovi.care/skincare/ae/ingredients/hexapeptide-and-hyaluronic-acid) - Work well together: [Hyaluronic acid and hexapeptide-9](https://lovi.care/skincare/ae/ingredients/hyaluronic-acid-and-hexapeptide-9) - Work well together: [Hyaluronic acid and palmitoyl pentapeptide-4](https://lovi.care/skincare/ae/ingredients/hyaluronic-acid-and-palmitoyl-pentapeptide-4) - Work well together: [Hyaluronic acid and palmitoyl tripeptide-1](https://lovi.care/skincare/ae/ingredients/hyaluronic-acid-and-palmitoyl-tripeptide-1) - Work well together: [Hyaluronic acid and peptide-rich plasma](https://lovi.care/skincare/ae/ingredients/hyaluronic-acid-and-peptide-rich-plasma) - Work well together: [Hyaluronic acid and triple peptide blend](https://lovi.care/skincare/ae/ingredients/hyaluronic-acid-and-triple-peptide-blend) - Work well together: [Gluconolactone and hyaluronic acid](https://lovi.care/skincare/ae/ingredients/gluconolactone-and-hyaluronic-acid) - Work well together: [Hyaluronic acid and lactobionic acid](https://lovi.care/skincare/ae/ingredients/hyaluronic-acid-and-lactobionic-acid) - Work well together: [Hyaluronic acid and ascorbyl glucoside](https://lovi.care/skincare/ae/ingredients/hyaluronic-acid-and-ascorbyl-glucoside) - Work well together: [Coenzyme Q10 and hyaluronic acid](https://lovi.care/skincare/ae/ingredients/coenzyme-q10-and-hyaluronic-acid) - Work well together: [Vitamin E and hyaluronic acid](https://lovi.care/skincare/ae/ingredients/vitamin-e-and-hyaluronic-acid) - Depends on the strength: [AHA blend glycolic and citric acids and hyaluronic acid](https://lovi.care/skincare/ae/ingredients/aha-blend-glycolic-and-citric-acids-and-hyaluronic-acid) - Depends on the strength: [Hyaluronic acid and citric acid](https://lovi.care/skincare/ae/ingredients/hyaluronic-acid-and-citric-acid) - Depends on the strength: [Glycolic acid and hyaluronic acid](https://lovi.care/skincare/ae/ingredients/glycolic-acid-and-hyaluronic-acid) - Depends on the strength: [Lactic acid and hyaluronic acid](https://lovi.care/skincare/ae/ingredients/lactic-acid-and-hyaluronic-acid) - Depends on the strength: [Mandelic acid and hyaluronic acid](https://lovi.care/skincare/ae/ingredients/mandelic-acid-and-hyaluronic-acid) - Depends on the strength: [Niacinamide and acetyl hexapeptide-3](https://lovi.care/skincare/ae/ingredients/niacinamide-and-acetyl-hexapeptide-3) - Work well together: [Panthenol and acetyl hexapeptide-3](https://lovi.care/skincare/ae/ingredients/panthenol-and-acetyl-hexapeptide-3) - Work well together: [Hyaluronic acid and tri-ceramide complex](https://lovi.care/skincare/ae/ingredients/hyaluronic-acid-and-tri-ceramide-complex) - Work well together: [Bakuchiol and acetyl hexapeptide-3](https://lovi.care/skincare/ae/ingredients/bakuchiol-and-acetyl-hexapeptide-3) - Keep them apart: [Azelaic acid and hyaluronic acid](https://lovi.care/skincare/ae/ingredients/azelaic-acid-and-hyaluronic-acid) - Keep them apart: [Salicylic acid and hyaluronic acid](https://lovi.care/skincare/ae/ingredients/salicylic-acid-and-hyaluronic-acid) - Work well together: [Arginine and acetyl hexapeptide-3](https://lovi.care/skincare/ae/ingredients/arginine-and-acetyl-hexapeptide-3) - Work well together: [Acetyl hexapeptide-3 and GABA](https://lovi.care/skincare/ae/ingredients/acetyl-hexapeptide-3-and-gaba) - Work well together: [Silk amino acids and acetyl hexapeptide-3](https://lovi.care/skincare/ae/ingredients/silk-amino-acids-and-acetyl-hexapeptide-3) - Work well together: [Taurine and acetyl hexapeptide-3](https://lovi.care/skincare/ae/ingredients/taurine-and-acetyl-hexapeptide-3) - Work well together: [Acetyl hexapeptide-3 and theanine](https://lovi.care/skincare/ae/ingredients/acetyl-hexapeptide-3-and-theanine) - Work well together: [Niacinamide and hyaluronic acid](https://lovi.care/skincare/ae/ingredients/niacinamide-and-hyaluronic-acid) - Keep them apart: [AHA blend glycolic and citric acids and acetyl hexapeptide-3](https://lovi.care/skincare/ae/ingredients/aha-blend-glycolic-and-citric-acids-and-acetyl-hexapeptide-3) - Keep them apart: [Acetyl hexapeptide-3 and citric acid](https://lovi.care/skincare/ae/ingredients/acetyl-hexapeptide-3-and-citric-acid) - Keep them apart: [Glycolic acid and acetyl hexapeptide-3](https://lovi.care/skincare/ae/ingredients/glycolic-acid-and-acetyl-hexapeptide-3) - Keep them apart: [Lactic acid and acetyl hexapeptide-3](https://lovi.care/skincare/ae/ingredients/lactic-acid-and-acetyl-hexapeptide-3) - Keep them apart: [Acetyl hexapeptide-3 and mandelic acid](https://lovi.care/skincare/ae/ingredients/acetyl-hexapeptide-3-and-mandelic-acid) - Work well together: [Coenzyme Q10 and acetyl hexapeptide-3](https://lovi.care/skincare/ae/ingredients/coenzyme-q10-and-acetyl-hexapeptide-3) - Work well together: [Green tea and acetyl hexapeptide-3](https://lovi.care/skincare/ae/ingredients/green-tea-and-acetyl-hexapeptide-3) - Work well together: [Vitamin E and acetyl hexapeptide-3](https://lovi.care/skincare/ae/ingredients/vitamin-e-and-acetyl-hexapeptide-3) - Keep them apart: [Hyaluronic acid and bergamot oil](https://lovi.care/skincare/ae/ingredients/hyaluronic-acid-and-bergamot-oil) - Keep them apart: [Hyaluronic acid and camphor oil](https://lovi.care/skincare/ae/ingredients/hyaluronic-acid-and-camphor-oil) - Keep them apart: [Hyaluronic acid and chamomile oil](https://lovi.care/skincare/ae/ingredients/hyaluronic-acid-and-chamomile-oil) - Keep them apart: [Hyaluronic acid and clove leaf oil](https://lovi.care/skincare/ae/ingredients/hyaluronic-acid-and-clove-leaf-oil) - Keep them apart: [Hyaluronic acid and eucalyptus oil](https://lovi.care/skincare/ae/ingredients/hyaluronic-acid-and-eucalyptus-oil) - Keep them apart: [Hyaluronic acid and geranium oil](https://lovi.care/skincare/ae/ingredients/hyaluronic-acid-and-geranium-oil) - Keep them apart: [Hyaluronic acid and grapefruit peel oil](https://lovi.care/skincare/ae/ingredients/hyaluronic-acid-and-grapefruit-peel-oil) - Keep them apart: [Lavender oil and hyaluronic acid](https://lovi.care/skincare/ae/ingredients/lavender-oil-and-hyaluronic-acid) - Keep them apart: [Hyaluronic acid and lemon oil](https://lovi.care/skincare/ae/ingredients/hyaluronic-acid-and-lemon-oil) - Keep them apart: [Hyaluronic acid and orange oil](https://lovi.care/skincare/ae/ingredients/hyaluronic-acid-and-orange-oil) - Keep them apart: [Hyaluronic acid and palmarosa oil](https://lovi.care/skincare/ae/ingredients/hyaluronic-acid-and-palmarosa-oil) - Keep them apart: [Hyaluronic acid and peppermint oil](https://lovi.care/skincare/ae/ingredients/hyaluronic-acid-and-peppermint-oil) - Keep them apart: [Hyaluronic acid and rose oil](https://lovi.care/skincare/ae/ingredients/hyaluronic-acid-and-rose-oil) - Keep them apart: [Hyaluronic acid and rosewood oil](https://lovi.care/skincare/ae/ingredients/hyaluronic-acid-and-rosewood-oil) - Keep them apart: [Hyaluronic acid and sandalwood oil](https://lovi.care/skincare/ae/ingredients/hyaluronic-acid-and-sandalwood-oil) - Keep them apart: [Tea tree oil and hyaluronic acid](https://lovi.care/skincare/ae/ingredients/tea-tree-oil-and-hyaluronic-acid) - Keep them apart: [Hyaluronic acid and thyme oil](https://lovi.care/skincare/ae/ingredients/hyaluronic-acid-and-thyme-oil) - Keep them apart: [Hyaluronic acid and wild mint oil](https://lovi.care/skincare/ae/ingredients/hyaluronic-acid-and-wild-mint-oil) - Work well together: [Acetyl hexapeptide-3 and beta-sitosterol](https://lovi.care/skincare/ae/ingredients/acetyl-hexapeptide-3-and-beta-sitosterol) - Work well together: [Ceramide-building complex and acetyl hexapeptide-3](https://lovi.care/skincare/ae/ingredients/ceramide-building-complex-and-acetyl-hexapeptide-3) - Work well together: [Acetyl hexapeptide-3 and cholesterol](https://lovi.care/skincare/ae/ingredients/acetyl-hexapeptide-3-and-cholesterol) - Work well together: [Acetyl hexapeptide-3 and phytosphingosine](https://lovi.care/skincare/ae/ingredients/acetyl-hexapeptide-3-and-phytosphingosine) - Work well together: [Acetyl hexapeptide-3 and phytosterol](https://lovi.care/skincare/ae/ingredients/acetyl-hexapeptide-3-and-phytosterol) - Work well together: [Acetyl hexapeptide-3 and squalene](https://lovi.care/skincare/ae/ingredients/acetyl-hexapeptide-3-and-squalene) - Work well together: [Acetyl hexapeptide-3 and tri-ceramide complex](https://lovi.care/skincare/ae/ingredients/acetyl-hexapeptide-3-and-tri-ceramide-complex) - Work well together: [Hyaluronic acid and cholesterol](https://lovi.care/skincare/ae/ingredients/hyaluronic-acid-and-cholesterol) - Work well together: [Hyaluronic acid and lauric acid](https://lovi.care/skincare/ae/ingredients/hyaluronic-acid-and-lauric-acid) - Work well together: [Linoleic acid and hyaluronic acid](https://lovi.care/skincare/ae/ingredients/linoleic-acid-and-hyaluronic-acid) - Keep them apart: [Hyaluronic acid and isopropyl alcohol](https://lovi.care/skincare/ae/ingredients/hyaluronic-acid-and-isopropyl-alcohol) - Keep them apart: [Salicylic acid and acetyl hexapeptide-3](https://lovi.care/skincare/ae/ingredients/salicylic-acid-and-acetyl-hexapeptide-3) - Keep them apart: [Acetyl hexapeptide-3 and baking soda](https://lovi.care/skincare/ae/ingredients/acetyl-hexapeptide-3-and-baking-soda) - Keep them apart: [Acetyl hexapeptide-3 and bleach](https://lovi.care/skincare/ae/ingredients/acetyl-hexapeptide-3-and-bleach) - Keep them apart: [Acetyl hexapeptide-3 and potassium hydroxide](https://lovi.care/skincare/ae/ingredients/acetyl-hexapeptide-3-and-potassium-hydroxide) - Keep them apart: [Acetyl hexapeptide-3 and behenyl alcohol](https://lovi.care/skincare/ae/ingredients/acetyl-hexapeptide-3-and-behenyl-alcohol) - Keep them apart: [Acetyl hexapeptide-3 and isopropyl alcohol](https://lovi.care/skincare/ae/ingredients/acetyl-hexapeptide-3-and-isopropyl-alcohol) - Keep them apart: [Acetyl hexapeptide-3 and polyvinyl alcohol](https://lovi.care/skincare/ae/ingredients/acetyl-hexapeptide-3-and-polyvinyl-alcohol) - Keep them apart: [Copper and acetyl hexapeptide-3](https://lovi.care/skincare/ae/ingredients/copper-and-acetyl-hexapeptide-3) - Work well together: [Arginine and hyaluronic acid](https://lovi.care/skincare/ae/ingredients/arginine-and-hyaluronic-acid) - Work well together: [Hyaluronic acid and GABA](https://lovi.care/skincare/ae/ingredients/hyaluronic-acid-and-gaba) - Work well together: [Silk amino acids and hyaluronic acid](https://lovi.care/skincare/ae/ingredients/silk-amino-acids-and-hyaluronic-acid) - Work well together: [Taurine and hyaluronic acid](https://lovi.care/skincare/ae/ingredients/taurine-and-hyaluronic-acid) - Work well together: [Hyaluronic acid and theanine](https://lovi.care/skincare/ae/ingredients/hyaluronic-acid-and-theanine) - Work well together: [Panthenol and hyaluronic acid](https://lovi.care/skincare/ae/ingredients/panthenol-and-hyaluronic-acid) - Keep them apart: [Magnesium and acetyl hexapeptide-3](https://lovi.care/skincare/ae/ingredients/magnesium-and-acetyl-hexapeptide-3) - Keep them apart: [Acetyl hexapeptide-3 and zinc](https://lovi.care/skincare/ae/ingredients/acetyl-hexapeptide-3-and-zinc) - Keep them apart: [Acetyl hexapeptide-3 and zinc sulfate](https://lovi.care/skincare/ae/ingredients/acetyl-hexapeptide-3-and-zinc-sulfate) - Keep them apart: [Benzoyl peroxide and acetyl hexapeptide-3](https://lovi.care/skincare/ae/ingredients/benzoyl-peroxide-and-acetyl-hexapeptide-3) - Work well together: [Vitamin C and hyaluronic acid](https://lovi.care/skincare/ae/ingredients/vitamin-c-and-hyaluronic-acid) - Keep them apart: [Azelaic acid and acetyl hexapeptide-3](https://lovi.care/skincare/ae/ingredients/azelaic-acid-and-acetyl-hexapeptide-3) - Keep them apart: [Acetyl hexapeptide-3 and protease](https://lovi.care/skincare/ae/ingredients/acetyl-hexapeptide-3-and-protease) - Keep them apart: [Acetyl hexapeptide-3 and superoxide dismutase](https://lovi.care/skincare/ae/ingredients/acetyl-hexapeptide-3-and-superoxide-dismutase) ## About the Lovi Fit Lovi: Unbiased, science-based skincare AI trained on real user outcomes. Lovi checks every pairing with brand-independent rules its dermatologists and cosmetic chemists build and review, and personalizes every pick with AI trained on the real results of millions of users. Lovi trains its fit score models on a proprietary dataset built from more than 10,000 expert-labeled products and more than 100,000 simulated examples, following an internally consistent methodology presented at Cosmoprof, AMWC, and Skin of Color Update. Levels from best to worst: Superior, High, Average, Low, Caution, Warning. Behind this pairing advice: Nadia Kapleva, MS (Co-founder, Medical Director); Alexey Shagraev, PhD (Co-founder, CEO and CTO); Dr. Sofía Perea Pérez, MD, MSc (Medical Board); Aishani Shah, MD (Medical Board); Asya Zubkova, MS (Medical Board); Hanna Kurets, MD (Medical Board, Medical Advisor); Elina Nazarenko, MD (Medical Board); Victoria Derkova, MS (Medical Board). Page built Nov 8, 2026. More from Lovi: https://lovi.care/skincare/llms.txt ## This page in other countries - United States: https://lovi.care/skincare/ingredients/acetyl-hexapeptide-3-and-hyaluronic-acid - United Kingdom: https://lovi.care/skincare/uk/ingredients/acetyl-hexapeptide-3-and-hyaluronic-acid - Ireland: https://lovi.care/skincare/ie/ingredients/acetyl-hexapeptide-3-and-hyaluronic-acid - Germany: https://lovi.care/skincare/de/ingredients/acetyl-hexapeptide-3-and-hyaluronic-acid - France: https://lovi.care/skincare/fr/ingredients/acetyl-hexapeptide-3-and-hyaluronic-acid - Italy: https://lovi.care/skincare/it/ingredients/acetyl-hexapeptide-3-and-hyaluronic-acid - Netherlands: https://lovi.care/skincare/nl/ingredients/acetyl-hexapeptide-3-and-hyaluronic-acid - Spain: https://lovi.care/skincare/es/ingredients/acetyl-hexapeptide-3-and-hyaluronic-acid - Canada: https://lovi.care/skincare/ca/ingredients/acetyl-hexapeptide-3-and-hyaluronic-acid - Australia: https://lovi.care/skincare/au/ingredients/acetyl-hexapeptide-3-and-hyaluronic-acid - Singapore: https://lovi.care/skincare/sg/ingredients/acetyl-hexapeptide-3-and-hyaluronic-acid - Saudi Arabia: https://lovi.care/skincare/sa/ingredients/acetyl-hexapeptide-3-and-hyaluronic-acid - United Arab Emirates: https://lovi.care/skincare/ae/ingredients/acetyl-hexapeptide-3-and-hyaluronic-acid (this page)