# Sesderma vs Silka Page: https://lovi.care/skincare/ae/compare/sesderma-vs-silka The Lovi Fit is the same in every country; only the stores and prices differ, and the ones here are for the United Arab Emirates. Sesderma and Silka are two skincare lines offering distinct paths to daily wellness. Sesderma is known for advanced [serums](https://lovi.care/skincare/ae/ingredients/serum) and engineered formulas featuring botanical [extracts](https://lovi.care/skincare/ae/ingredients/extract) and active compounds, while the latter is beloved for thoughtful serums and effective formulas like the [Papaya](https://lovi.care/skincare/ae/ingredients/papaya) Soap for acne-prone skin. The Spanish brand suits sensitive, hyperpigmented, and aging skin types best, whereas Silka suits balanced, oily, dry, combination, and sensitive skin best. Both brands differ because the former relies on synergistic ingredients to refine skin texture and promote a radiant complexion, while its counterpart delivers gentle and reliable care for daily routines. Sesderma is a Spanish skincare brand founded in 1989 and owned by Grupo Sesderma since 2026. [skinexpert.sesderma.com](https://skinexpert.sesderma.com/en/jb-capital-joins-the-shareholding-of-sesderma-group-as-a-strategic-partner/) [sesderma.com](https://www.sesderma.com/us_en/about-us.html) This page compares some of the most popular Sesderma and Silka products; for every product of both brands, with a fit score for your own skin, [use the Lovi app](https://app.pora.ai/vqqJ/j1xj2b6o?af_sub2=compare&af_sub3=selection_note&af_sub4=pg3e7d5e8147). ### Popular Sesderma vs Silka products #### Sesderma - [Azelac RU Serum](https://lovi.care/skincare/ae/p/sesderma/azelac-ru-serum/for/acne-prone-skin) — High fit — [AED 123.63 at Amazon](https://www.amazon.ae/dp/B00987RKWW?tag=lovi00-21&linkCode=osi&th=1&psc=1) #### Silka - [Papaya Soap](https://lovi.care/skincare/ae/p/silka/papaya-soap/for/dark-spots) — Average fit ### Sesderma vs Silka [serums](https://lovi.care/skincare/ae/ingredients/serum) and treatments #### Sesderma - [Azelac RU Serum](https://lovi.care/skincare/ae/p/sesderma/azelac-ru-serum/for/acne-prone-skin) — High fit — [AED 123.63 at Amazon](https://www.amazon.ae/dp/B00987RKWW?tag=lovi00-21&linkCode=osi&th=1&psc=1) #### Silka - [Papaya Soap](https://lovi.care/skincare/ae/p/silka/papaya-soap/for/dark-spots) — Average fit ## Questions and answers ### Sesderma or Silka: which is better? Sesderma offers a High Lovi fit for acne-prone skin and skin with dark spots with its Azelac RU [Serum](https://lovi.care/skincare/ae/ingredients/serum), while Silka provides only Average fits for those skin concerns through its [Papaya](https://lovi.care/skincare/ae/ingredients/papaya) Soap. [Azelaic acid](https://lovi.care/skincare/ae/ingredients/azelaic-acid) helps improve acne vulgaris. [Pharmaceutics, 2021](https://pubmed.ncbi.nlm.nih.gov/33923739/) ### What is the difference between Sesderma and Silka? For skin with dark spots, Sesderma offers a High fit with its Azelac RU Serum, whereas Silka Papaya Soap only reaches an Average fit. Lovi rates Sesderma's Azelac RU Serum as High for acne-prone, combination, and dark spot skin types, while Silka's soap rates lower across these categories. ### Which is more affordable, Sesderma or Silka? Neither Sesderma nor Silka has pricing information provided on this page. ### Which causes fewer breakouts, Sesderma or Silka? For acne-prone skin, Lovi rates Sesderma's Azelac RU Serum as High, whereas Silka's Papaya Soap is rated Low. Azelaic acid helps treat acne vulgaris. [Pharmaceutics, 2021](https://pubmed.ncbi.nlm.nih.gov/33923739/) ### Which brand has been established longer, Sesderma or Silka? Sesderma has been established longer, having been founded in Spain in 1989, whereas Silka was founded in 2001. ### Do products from Sesderma or Silka contain fragrance? Sesderma includes fragrance in its Azelac RU Serum on this page. Silka products on this page list no fragrance in their ingredients. ### How does the Lovi fit level of Sesderma's Azelac RU Serum compare to Silka's Papaya Soap for acne-prone skin? For acne-prone skin, Lovi rates Sesderma's Azelac RU Serum as High, while Silka's Papaya Soap receives a Low fit. [Pharmaceutics, 2021](https://pubmed.ncbi.nlm.nih.gov/33923739/) ## Research behind their key ingredients - [Vitamin A antagonizes decreased cell growth and elevated collagen-degrading matrix metalloproteinases and stimulates collagen accumulation in naturally aged human skin](https://pubmed.ncbi.nlm.nih.gov/10692106/) Retinol · The Journal of Investigative Dermatology, 2000 - [The effect of niacinamide on reducing cutaneous pigmentation and suppression of melanosome transfer](https://pubmed.ncbi.nlm.nih.gov/12100180/) Niacinamide · The British Journal of Dermatology, 2002 - [Improvement of naturally aged skin with vitamin A (retinol)](https://pubmed.ncbi.nlm.nih.gov/17515510/) Retinol · Archives of Dermatology, 2007 - [Nicotinic acid/niacinamide and the skin](https://pubmed.ncbi.nlm.nih.gov/17147561/) Niacin · Journal of Cosmetic Dermatology, 2004 - [Molecular basis of retinol anti-ageing properties in naturally aged human skin in vivo](https://pubmed.ncbi.nlm.nih.gov/27261203/) Retinol · International Journal of Cosmetic Science, 2017 - [Prospective, randomized, double-blind assessment of topical bakuchiol and retinol for facial photoageing](https://pubmed.ncbi.nlm.nih.gov/29947134/) Retinol · The British Journal of Dermatology, 2019 - [Efficacy and Safety of Azelaic Acid Nanocrystal-Loaded In Situ Hydrogel in the Treatment of Acne Vulgaris](https://pubmed.ncbi.nlm.nih.gov/33923739/) Azelaic acid · Pharmaceutics, 2021 - [A topical lipophilic niacin derivative increases NAD, epidermal differentiation and barrier function in photodamaged skin](https://pubmed.ncbi.nlm.nih.gov/17518989/) Niacin · Experimental Dermatology, 2007 - [The 24-hour skin hydration and barrier function effects of a hyaluronic 1%, glycerin 5%, and Centella asiatica stem cells extract moisturizing fluid: an intra-subject, randomized, assessor-blinded study](https://pubmed.ncbi.nlm.nih.gov/28860834/) Glycerin · Clinical, Cosmetic and Investigational Dermatology, 2017 - [A Double-Blinded, Randomized, Vehicle-Controlled Study of the Efficacy of Moisturizer Containing Licochalcone A, Decanediol, L-Carnitine, and Salicylic Acid for Prevention of Acne Relapse in Asian Population](https://pubmed.ncbi.nlm.nih.gov/33150170/) Salicylic acid · BioMed Research International, 2020 - [Efficacy of a multitargeted, salicylic acid-based dermocosmetic cream compared to benzoyl peroxide 5% in Acne vulgaris: Results from a randomized study](https://pubmed.ncbi.nlm.nih.gov/37941097/) Salicylic acid · Journal of Cosmetic Dermatology, 2024 - [Effects of 15% Azelaic Acid Gel in the Management of Post-Inflammatory Erythema and Post-Inflammatory Hyperpigmentation in Acne Vulgaris](https://pubmed.ncbi.nlm.nih.gov/38734843/) Azelaic acid · Dermatology and Therapy, 2024 - [A Salicylic Acid-Based Dermocosmetic is Effective as an Adjunct to Benzoyl Peroxide for Mild to Moderate Acne and as Monotherapy in Maintenance Post Benzoyl Peroxide](https://pubmed.ncbi.nlm.nih.gov/38051857/) Salicylic acid · Journal of Drugs in Dermatology, 2023 - [Influence of vitamin E acetate on stratum corneum hydration](https://pubmed.ncbi.nlm.nih.gov/9706379/) Tocopheryl acetate · Arzneimittel-Forschung, 1998 - [Nanostructured Lipid Carrier Based Gel Containing α-Tocopherol and α-Tocopheryl Acetate for Synergistic Cutaneous Antiaging Efficacy](https://pubmed.ncbi.nlm.nih.gov/41309687/) Tocopheryl acetate vitamin e · Scientific Reports, 2025 - [Safety assessment on comedogenicity of dermatological products containing d-alpha tocopheryl acetate in Asian subjects: A double-blind randomized controlled trial](https://pubmed.ncbi.nlm.nih.gov/34471722/) Tocopheryl acetate · Contemporary Clinical Trials Communications, 2021 - [The efficacy of enoxolone in reducing erythema and pain after laser treatment: A randomized split-face pilot study](https://pubmed.ncbi.nlm.nih.gov/38622995/) Glycyrrhetinic acid · Journal of Cosmetic Dermatology, 2024 ## The brands - Spanish skincare: [Sesderma](https://lovi.care/skincare/ae/brands/sesderma) - Skincare: [Silka](https://lovi.care/skincare/ae/brands/silka) ## More comparisons - [SKIN1004 vs Sesderma](https://lovi.care/skincare/ae/compare/skin1004-vs-sesderma) - [SKIN1004 vs Silka](https://lovi.care/skincare/ae/compare/skin1004-vs-silka) - [Anua vs Sesderma](https://lovi.care/skincare/ae/compare/anua-vs-sesderma) - [Anua vs Silka](https://lovi.care/skincare/ae/compare/anua-vs-silka) - [Medicube vs Sesderma](https://lovi.care/skincare/ae/compare/medicube-vs-sesderma) - [Medicube vs Silka](https://lovi.care/skincare/ae/compare/medicube-vs-silka) - [The Ordinary vs Sesderma](https://lovi.care/skincare/ae/compare/the-ordinary-vs-sesderma) - [The Ordinary vs Silka](https://lovi.care/skincare/ae/compare/the-ordinary-vs-silka) - [Beauty of Joseon vs Sesderma](https://lovi.care/skincare/ae/compare/beauty-of-joseon-vs-sesderma) - [Beauty of Joseon vs Silka](https://lovi.care/skincare/ae/compare/beauty-of-joseon-vs-silka) - [COSRX vs Sesderma](https://lovi.care/skincare/ae/compare/cosrx-vs-sesderma) - [COSRX vs Silka](https://lovi.care/skincare/ae/compare/cosrx-vs-silka) - [CeraVe vs Sesderma](https://lovi.care/skincare/ae/compare/cerave-vs-sesderma) - [CeraVe vs Silka](https://lovi.care/skincare/ae/compare/cerave-vs-silka) - [La Roche-Posay vs Sesderma](https://lovi.care/skincare/ae/compare/la-roche-posay-vs-sesderma) - [La Roche-Posay vs Silka](https://lovi.care/skincare/ae/compare/la-roche-posay-vs-silka) - [Dr. Althea vs Sesderma](https://lovi.care/skincare/ae/compare/dr-althea-vs-sesderma) - [Dr. Althea vs Silka](https://lovi.care/skincare/ae/compare/dr-althea-vs-silka) - [Some By Mi vs Sesderma](https://lovi.care/skincare/ae/compare/some-by-mi-vs-sesderma) - [Some By Mi vs Silka](https://lovi.care/skincare/ae/compare/some-by-mi-vs-silka) ## About the Lovi Fit Lovi: Unbiased, science-based skincare AI trained on real user outcomes. Lovi compares products by their fit scores, calculated from the full ingredient list with brand-independent rules its dermatologists and cosmetic chemists build and review, and personalizes every pick with AI trained on the real results of millions of users. Lovi trains its fit score models on a proprietary dataset built from more than 10,000 expert-labeled products and more than 100,000 simulated examples, following an internally consistent methodology presented at Cosmoprof, AMWC, and Skin of Color Update. Levels from best to worst: Superior, High, Average, Low, Caution, Warning. Behind this comparison: Nadia Kapleva, MS (Co-founder, Medical Director); Alexey Shagraev, PhD (Co-founder, CEO and CTO); Dr. Sofía Perea Pérez, MD, MSc (Medical Board); Aishani Shah, MD (Medical Board); Asya Zubkova, MS (Medical Board); Hanna Kurets, MD (Medical Board, Medical Advisor); Elina Nazarenko, MD (Medical Board); Victoria Derkova, MS (Medical Board). Page built Nov 8, 2026. More from Lovi: https://lovi.care/skincare/llms.txt ## This page in other countries - United States: https://lovi.care/skincare/compare/sesderma-vs-silka - United Kingdom: https://lovi.care/skincare/uk/compare/sesderma-vs-silka - Ireland: https://lovi.care/skincare/ie/compare/sesderma-vs-silka - Germany: https://lovi.care/skincare/de/compare/sesderma-vs-silka - France: https://lovi.care/skincare/fr/compare/sesderma-vs-silka - Italy: https://lovi.care/skincare/it/compare/sesderma-vs-silka - Netherlands: https://lovi.care/skincare/nl/compare/sesderma-vs-silka - Spain: https://lovi.care/skincare/es/compare/sesderma-vs-silka - Canada: https://lovi.care/skincare/ca/compare/sesderma-vs-silka - Australia: https://lovi.care/skincare/au/compare/sesderma-vs-silka - Singapore: https://lovi.care/skincare/sg/compare/sesderma-vs-silka - Saudi Arabia: https://lovi.care/skincare/sa/compare/sesderma-vs-silka - United Arab Emirates: https://lovi.care/skincare/ae/compare/sesderma-vs-silka (this page)