# Sesderma vs ELIDEL

Page: https://lovi.care/skincare/ae/compare/sesderma-vs-elidel

The Lovi Fit is the same in every country; only the stores and prices differ, and the ones here are for the United Arab Emirates.

Sesderma and ELIDEL are distinct skincare options, with the former being a Spanish brand founded in 1989 and the latter a Swiss brand established in 2001. Sesderma is beloved for its advanced [serums](https://lovi.care/skincare/ae/ingredients/serum) and meticulously engineered formulas, while the brand ELIDEL is known for its gentle moisturizers and soothing formulas. The former suits sensitive, hyperpigmented, and aging skin types best with standout items like the Azelac RU Serum, whereas both brands offer targeted solutions, with the latter suiting sensitive and dry skin best through options like [Pimecrolimus](https://lovi.care/skincare/ae/ingredients/pimecrolimus). They differ primarily in their active ingredients and primary concentrations, utilizing botanical [extracts](https://lovi.care/skincare/ae/ingredients/extract) or balanced compositions to refine texture or maintain daily skin health.

Sesderma is a Spanish skincare brand founded in 1989 and owned by Grupo Sesderma since 2026.

[skinexpert.sesderma.com](https://skinexpert.sesderma.com/en/jb-capital-joins-the-shareholding-of-sesderma-group-as-a-strategic-partner/) [sesderma.com](https://www.sesderma.com/us_en/about-us.html)

ELIDEL is a Swiss skincare brand founded in 2001 and owned by Viatris Inc. since 2016.

[myelidel.ca](https://myelidel.ca/en/) [en.wikipedia.org](https://en.wikipedia.org/wiki/Viatris) [investor.mylan.com](https://investor.mylan.com/news-releases/news-release-details/mylan-completes-acquisition-meda) [sec.gov](https://www.sec.gov/Archives/edgar/data/1114448/000104746904022516/a2139722z6-k.htm)

This page compares some of the most popular Sesderma and ELIDEL products; for every product of both brands, with a fit score for your own skin, [use the Lovi app](https://app.pora.ai/vqqJ/j1xj2b6o?af_sub2=compare&af_sub3=selection_note&af_sub4=pgc73d77a727).

### Popular Sesderma vs ELIDEL products

#### Sesderma

- [Azelac RU Serum](https://lovi.care/skincare/ae/p/sesderma/azelac-ru-serum/for/acne-prone-skin) — High fit — [AED 123.63 at Amazon](https://www.amazon.ae/dp/B00987RKWW?tag=lovi00-21&linkCode=osi&th=1&psc=1)

#### ELIDEL

- [Pimecrolimus](https://lovi.care/skincare/ae/p/elidel/pimecrolimus/for/dry-sensitive-skin) — Average fit

## Questions and answers

### Sesderma or ELIDEL: which is better?

Sesderma offers better fit levels for most skin types on this page, with High fit ratings for acne-prone, dark spot, and combination skin, whereas ELIDEL products on this page mostly rate as Average or lower.

[Pharmaceutics, 2021](https://pubmed.ncbi.nlm.nih.gov/33923739/)

### What is the difference between Sesderma and ELIDEL?

Sesderma offers products on this page like Azelac RU [Serum](https://lovi.care/skincare/ae/ingredients/serum) that has a High Lovi fit for acne-prone skin, whereas ELIDEL features [Pimecrolimus](https://lovi.care/skincare/ae/ingredients/pimecrolimus) which has an Average fit for dry sensitive skin and contains no fragrance.

[Pharmaceutics, 2021](https://pubmed.ncbi.nlm.nih.gov/33923739/)

### Which is more affordable, Sesderma or ELIDEL?

Neither Sesderma nor ELIDEL shows price information on this page, so affordability cannot be compared here.

### Which causes fewer breakouts, Sesderma or ELIDEL?

For acne-prone skin, the products on this page by Sesderma show a High fit level, whereas ELIDEL shows a Low fit level. This suggests Sesderma helps better with breakouts.

[Pharmaceutics, 2021](https://pubmed.ncbi.nlm.nih.gov/33923739/)

### Where were Sesderma and ELIDEL founded and who owns them?

Sesderma was founded in Spain in 1989 and is owned by Grupo Sesderma since 2026. ELIDEL was founded in Switzerland in 2001 and is owned by Viatris Inc. since 2016.

### Which products are listed for Sesderma and ELIDEL on the page, and what are their product types?

Sesderma lists the Azelac RU Serum, and ELIDEL lists the Pimecrolimus moisturizer on the products on this page.

### Do Sesderma and ELIDEL products contain fragrance?

Sesderma includes fragrance in the products on this page, whereas ELIDEL lists no fragrance in its ingredients.

## Research behind their key ingredients

- [Vitamin A antagonizes decreased cell growth and elevated collagen-degrading matrix metalloproteinases and stimulates collagen accumulation in naturally aged human skin](https://pubmed.ncbi.nlm.nih.gov/10692106/) Retinol · The Journal of Investigative Dermatology, 2000
- [The effect of niacinamide on reducing cutaneous pigmentation and suppression of melanosome transfer](https://pubmed.ncbi.nlm.nih.gov/12100180/) Niacinamide · The British Journal of Dermatology, 2002
- [Improvement of naturally aged skin with vitamin A (retinol)](https://pubmed.ncbi.nlm.nih.gov/17515510/) Retinol · Archives of Dermatology, 2007
- [Nicotinic acid/niacinamide and the skin](https://pubmed.ncbi.nlm.nih.gov/17147561/) Niacin · Journal of Cosmetic Dermatology, 2004
- [Molecular basis of retinol anti-ageing properties in naturally aged human skin in vivo](https://pubmed.ncbi.nlm.nih.gov/27261203/) Retinol · International Journal of Cosmetic Science, 2017
- [Prospective, randomized, double-blind assessment of topical bakuchiol and retinol for facial photoageing](https://pubmed.ncbi.nlm.nih.gov/29947134/) Retinol · The British Journal of Dermatology, 2019
- [Efficacy and Safety of Azelaic Acid Nanocrystal-Loaded In Situ Hydrogel in the Treatment of Acne Vulgaris](https://pubmed.ncbi.nlm.nih.gov/33923739/) Azelaic acid · Pharmaceutics, 2021
- [A topical lipophilic niacin derivative increases NAD, epidermal differentiation and barrier function in photodamaged skin](https://pubmed.ncbi.nlm.nih.gov/17518989/) Niacin · Experimental Dermatology, 2007
- [Effects of 15% Azelaic Acid Gel in the Management of Post-Inflammatory Erythema and Post-Inflammatory Hyperpigmentation in Acne Vulgaris](https://pubmed.ncbi.nlm.nih.gov/38734843/) Azelaic acid · Dermatology and Therapy, 2024
- [Influence of vitamin E acetate on stratum corneum hydration](https://pubmed.ncbi.nlm.nih.gov/9706379/) Tocopheryl acetate · Arzneimittel-Forschung, 1998
- [Nanostructured Lipid Carrier Based Gel Containing α-Tocopherol and α-Tocopheryl Acetate for Synergistic Cutaneous Antiaging Efficacy](https://pubmed.ncbi.nlm.nih.gov/41309687/) Tocopheryl acetate · Scientific Reports, 2025
- [Safety assessment on comedogenicity of dermatological products containing d-alpha tocopheryl acetate in Asian subjects: A double-blind randomized controlled trial](https://pubmed.ncbi.nlm.nih.gov/34471722/) Tocopheryl acetate · Contemporary Clinical Trials Communications, 2021
- [The efficacy of enoxolone in reducing erythema and pain after laser treatment: A randomized split-face pilot study](https://pubmed.ncbi.nlm.nih.gov/38622995/) Glycyrrhetinic acid · Journal of Cosmetic Dermatology, 2024
- [Clinical Evaluation of a Soap-Free Cleansing Lotion Containing Sodium Cocoyl Apple Amino Acids for Effective Impurity Removal and Skin Barrier Preservation in Healthy Adults With Diverse Skin Types](https://pubmed.ncbi.nlm.nih.gov/40978887/) Cetyl alcohol · Cureus, 2025

## The brands

- Spanish skincare: [Sesderma](https://lovi.care/skincare/ae/brands/sesderma)
- Swiss skincare: [ELIDEL](https://lovi.care/skincare/ae/brands/elidel)

## More comparisons

- [SKIN1004 vs Sesderma](https://lovi.care/skincare/ae/compare/skin1004-vs-sesderma)
- [SKIN1004 vs ELIDEL](https://lovi.care/skincare/ae/compare/skin1004-vs-elidel)
- [Anua vs Sesderma](https://lovi.care/skincare/ae/compare/anua-vs-sesderma)
- [Anua vs ELIDEL](https://lovi.care/skincare/ae/compare/anua-vs-elidel)
- [Medicube vs Sesderma](https://lovi.care/skincare/ae/compare/medicube-vs-sesderma)
- [Medicube vs ELIDEL](https://lovi.care/skincare/ae/compare/medicube-vs-elidel)
- [The Ordinary vs Sesderma](https://lovi.care/skincare/ae/compare/the-ordinary-vs-sesderma)
- [The Ordinary vs ELIDEL](https://lovi.care/skincare/ae/compare/the-ordinary-vs-elidel)
- [Beauty of Joseon vs Sesderma](https://lovi.care/skincare/ae/compare/beauty-of-joseon-vs-sesderma)
- [Beauty of Joseon vs ELIDEL](https://lovi.care/skincare/ae/compare/beauty-of-joseon-vs-elidel)
- [COSRX vs Sesderma](https://lovi.care/skincare/ae/compare/cosrx-vs-sesderma)
- [COSRX vs ELIDEL](https://lovi.care/skincare/ae/compare/cosrx-vs-elidel)
- [CeraVe vs Sesderma](https://lovi.care/skincare/ae/compare/cerave-vs-sesderma)
- [CeraVe vs ELIDEL](https://lovi.care/skincare/ae/compare/cerave-vs-elidel)
- [La Roche-Posay vs Sesderma](https://lovi.care/skincare/ae/compare/la-roche-posay-vs-sesderma)
- [La Roche-Posay vs ELIDEL](https://lovi.care/skincare/ae/compare/la-roche-posay-vs-elidel)
- [Dr. Althea vs Sesderma](https://lovi.care/skincare/ae/compare/dr-althea-vs-sesderma)
- [Dr. Althea vs ELIDEL](https://lovi.care/skincare/ae/compare/dr-althea-vs-elidel)
- [Some By Mi vs Sesderma](https://lovi.care/skincare/ae/compare/some-by-mi-vs-sesderma)
- [Some By Mi vs ELIDEL](https://lovi.care/skincare/ae/compare/some-by-mi-vs-elidel)

## About the Lovi Fit

Lovi: Unbiased, science-based skincare AI trained on real user outcomes.

Lovi compares products by their fit scores, calculated from the full ingredient list with brand-independent rules its dermatologists and cosmetic chemists build and review, and personalizes every pick with AI trained on the real results of millions of users. Lovi trains its fit score models on a proprietary dataset built from more than 10,000 expert-labeled products and more than 100,000 simulated examples, following an internally consistent methodology presented at Cosmoprof, AMWC, and Skin of Color Update. Levels from best to worst: Superior, High, Average, Low, Caution, Warning.

Behind this comparison: Nadia Kapleva, MS (Co-founder, Medical Director); Alexey Shagraev, PhD (Co-founder, CEO and CTO); Dr. Sofía Perea Pérez, MD, MSc (Medical Board); Aishani Shah, MD (Medical Board); Asya Zubkova, MS (Medical Board); Hanna Kurets, MD (Medical Board, Medical Advisor); Elina Nazarenko, MD (Medical Board); Victoria Derkova, MS (Medical Board).

Page built Nov 8, 2026.

More from Lovi: https://lovi.care/skincare/llms.txt

## This page in other countries

- United States: https://lovi.care/skincare/compare/sesderma-vs-elidel
- United Kingdom: https://lovi.care/skincare/uk/compare/sesderma-vs-elidel
- Ireland: https://lovi.care/skincare/ie/compare/sesderma-vs-elidel
- Germany: https://lovi.care/skincare/de/compare/sesderma-vs-elidel
- France: https://lovi.care/skincare/fr/compare/sesderma-vs-elidel
- Italy: https://lovi.care/skincare/it/compare/sesderma-vs-elidel
- Netherlands: https://lovi.care/skincare/nl/compare/sesderma-vs-elidel
- Spain: https://lovi.care/skincare/es/compare/sesderma-vs-elidel
- Canada: https://lovi.care/skincare/ca/compare/sesderma-vs-elidel
- Australia: https://lovi.care/skincare/au/compare/sesderma-vs-elidel
- Singapore: https://lovi.care/skincare/sg/compare/sesderma-vs-elidel
- Saudi Arabia: https://lovi.care/skincare/sa/compare/sesderma-vs-elidel
- United Arab Emirates: https://lovi.care/skincare/ae/compare/sesderma-vs-elidel (this page)
