# Sebamed vs Natura Bissé

Page: https://lovi.care/skincare/ae/compare/sebamed-vs-natura-bisse

The Lovi Fit is the same in every country; only the stores and prices differ, and the ones here are for the United Arab Emirates.

Sebamed and Natura Bissé are distinct European skincare houses that offer tailored approaches to complexion health. The German brand is known for gentle cleansers and thoughtful moisturizers that suit sensitive, reactive, and problematic skin best through scientifically balanced, skin-neutral formulas. Meanwhile, the Spanish brand is celebrated for luxurious moisturizers and advanced formulas that suit mature, dry, and sensitive skin best with rich nourishing properties. Both lines differ fundamentally in their heritage and targeted concentrations, allowing individuals to choose between steady barrier maintenance and restorative vitality.

Sebamed is a German skincare brand founded in 1967 and owned by Sebapharma GmbH & Co. KG.

[sebamed.ae](https://sebamed.ae/en/article/2/Sebapharma) [sebamed.com](https://sebamed.com/en/info/company/about-us/) [en.wikipedia.org](https://en.wikipedia.org/wiki/Sebamed) [de.wikipedia.org](https://de.wikipedia.org/wiki/Sebamed)

Natura Bissé is a Spanish skincare brand founded in 1979 and owned by Natura Bissé International, S.A..

[naturabisse.com](https://www.naturabisse.com/int/en/our-story.html) [tracxn.com](https://tracxn.com/d/accelerator-incubator/ushopal/__yjGH7DKhQGNWnINKarEuFce6tilrPzGJv0PnASFLfpg)

This page compares some of the most popular Sebamed and Natura Bissé products; for every product of both brands, with a fit score for your own skin, [use the Lovi app](https://app.pora.ai/vqqJ/j1xj2b6o?af_sub2=compare&af_sub3=selection_note&af_sub4=pgf0cccd355a).

### Popular Sebamed vs Natura Bissé products

#### Natura Bissé

- [Diamond Extreme](https://lovi.care/skincare/ae/p/natura-bisse/diamond-extreme/for/mature-skin) — Superior fit — [AED 1,043.04 at Amazon](https://www.amazon.ae/dp/B0BKLRMKZV?tag=lovi00-21&linkCode=osi&th=1&psc=1)

#### Sebamed

- [Clear Face Care Gel](https://lovi.care/skincare/ae/p/sebamed/clear-face-care-gel/for/oily-acne-prone-skin) — High fit — [AED 109.89 at Amazon](https://www.amazon.ae/dp/B003NTJJR0?tag=lovi00-21&linkCode=osi&th=1&psc=1)
- [Facial Cleanser](https://lovi.care/skincare/ae/p/sebamed/facial-cleanser/for/combination-skin) — High fit

## Questions and answers

### Sebamed or Natura Bissé: which is better?

Sebamed is better for oily acne-prone skin because Lovi rates its products as High for that skin type, whereas Natura Bissé's Diamond Extreme is rated Low. Every Sebamed product on this page also lists no fragrance in its ingredients.

### What is the difference between Sebamed and Natura Bissé?

Sebamed is a German brand whose products on this page list no fragrance, whereas Natura Bissé's Diamond Extreme cream includes fragrance. Lovi gives Natura Bissé a Superior fit for mature skin, while Sebamed's products achieve High fits for oily and acne-prone skin types.

### Sebamed or Natura Bissé: which moisturizer is better?

For mature skin, Natura Bissé Diamond Extreme is better because Lovi gives it a Superior fit, whereas Sebamed Clear Face Care Gel has an Average fit. Natura Bissé Diamond Extreme also has a High fit for dry skin, dry sensitive skin, and skin with dark spots, while Sebamed Clear Face Care Gel only has an Average fit for those skin types.

### Which is more affordable, Sebamed or Natura Bissé?

The provided page facts and studies do not mention the prices of Sebamed or Natura Bisse products, so it is not possible to determine which brand is more affordable.

### Which causes fewer breakouts, Sebamed or Natura Bissé?

Sebamed is better for acne-prone skin because the products on this page have a High fit for oily acne-prone skin, while Natura Bissé has a Low fit.

### Which brand was founded earlier, Sebamed or Natura Bissé, and in which countries?

Sebamed was founded earlier than Natura Bissé. Sebamed started in Germany, while Natura Bissé was founded in Spain.

### Do all Sebamed products on this page avoid fragrance, whereas Natura Bissé includes fragrance in its moisturizer?

Yes, every Sebamed product on this page lists no fragrance in its ingredients, whereas Natura Bissé includes fragrance in its Diamond Extreme moisturizer.

### How does the Lovi fit level for oily acne-prone skin compare between Sebamed's Clear Face Care Gel and Natura Bissé's Diamond Extreme?

For oily acne-prone skin, Lovi gives Sebamed's Clear Face Care Gel a High fit, while Natura Bissé's Diamond Extreme receives a Low fit.

## Research behind their key ingredients

- [Benefits of topical hyaluronic acid for skin quality and signs of skin aging: From literature review to clinical evidence](https://pubmed.ncbi.nlm.nih.gov/36200921/) Sodium hyaluronate · Dermatologic Therapy, 2022
- [Topical use of dexpanthenol in skin disorders](https://pubmed.ncbi.nlm.nih.gov/12113650/) Panthenol · American Journal of Clinical Dermatology, 2002
- [The effects of a topical gel containing chitosan, 0,2% chlorhexidine, allantoin and despanthenol on the wound healing process subsequent to impacted lower third molar extraction](https://pubmed.ncbi.nlm.nih.gov/27475700/) Allantoin · Medicina Oral, Patologia Oral Y Cirugia Bucal, 2016
- [Treatment of acne with a combination of propolis, tea tree oil, and Aloe vera compared to erythromycin cream: two double-blind investigations](https://pubmed.ncbi.nlm.nih.gov/30588129/) Aloe barbadensis leaf juice · Clinical Pharmacology, 2018
- [The 24-hour skin hydration and barrier function effects of a hyaluronic 1%, glycerin 5%, and Centella asiatica stem cells extract moisturizing fluid: an intra-subject, randomized, assessor-blinded study](https://pubmed.ncbi.nlm.nih.gov/28860834/) Glycerin · Clinical, Cosmetic and Investigational Dermatology, 2017
- [Anti-Aging Effects of Leontopodium alpinum (Edelweiss) Callus Culture Extract Through Transcriptome Profiling](https://pubmed.ncbi.nlm.nih.gov/32098197/) Leontopodium alpinum leaf extract flower · Genes, 2020
- [Anti-inflammatory effects of concentrated ethanol extracts of Edelweiss (Leontopodium alpinum Cass.) callus cultures towards human keratinocytes and endothelial cells](https://pubmed.ncbi.nlm.nih.gov/23093820/) Leontopodium alpinum leaf extract flower · Mediators of Inflammation, 2012
- [A new topical panthenol-containing emollient: Results from two randomized controlled studies assessing its skin moisturization and barrier restoration potential, and the effect on skin microflora](https://pubmed.ncbi.nlm.nih.gov/27425824/) Panthenol · The Journal of Dermatological Treatment, 2017
- [Efficacy of a topical gel containing chitosan, chlorhexidine, allantoin and dexpanthenol for pain and inflammation control after third molar surgery: A randomized and placebo-controlled clinical trial](https://pubmed.ncbi.nlm.nih.gov/32683390/) Allantoin · Medicina Oral, Patologia Oral Y Cirugia Bucal, 2020
- [High molecular compounds (polysaccharides and proanthocyanidins) from Hamamelis virginiana bark: influence on human skin keratinocyte proliferation and differentiation and influence on irritated skin](https://pubmed.ncbi.nlm.nih.gov/11684194/) Witch hazel bark extract · Phytochemistry, 2001
- [Rosmarinic Acid, as an NHE1 Activator, Decreases Skin Surface pH and Improves the Skin Barrier Function](https://pubmed.ncbi.nlm.nih.gov/35409270/) Rosamarinus officinalis leaf extract rosemary leaf extract · International Journal of Molecular Sciences, 2022
- [Evaluation of dermal extracellular matrix and epidermal-dermal junction modifications using matrix-assisted laser desorption/ionization mass spectrometric imaging, in vivo reflectance confocal microscopy, echography, and histology: effect of age and peptide applications](https://pubmed.ncbi.nlm.nih.gov/25817264/) Palmitoyl tetrapeptide-7 · Journal of Cosmetic Dermatology, 2015
- [Effect of seasonal and geographical differences on skin and effect of treatment with an osmoprotectant: Sorbitol](https://pubmed.ncbi.nlm.nih.gov/23752031/) Sorbitol · Journal of Cosmetic Science, 2013
- [Evaluation of the Efficacy and Safety of a Panthenol-Enriched Mask for Skin Barrier Recovery After Facial Laser Treatment: Results of a Double-Blind Randomized Controlled Study](https://pubmed.ncbi.nlm.nih.gov/40613435/) Panthenol · Journal of Cosmetic Dermatology, 2025
- [Formulation and evaluation of exotic fat based cosmeceuticals for skin repair](https://pubmed.ncbi.nlm.nih.gov/20046792/) Mangifera indica seed butter · Indian Journal of Pharmaceutical Sciences, 2008
- [Effect of an Emollient Emulsion Containing 15.0% of Caprylic/Capric Triglyceride on the Urocanic Acid of the Stratum Corneum](https://pubmed.ncbi.nlm.nih.gov/37109405/) Caprylic capric triglyceride · Life, 2023
- [Efficacy and safety of combination cream of stimu-tex AS™ (spent grain wax, Argania Spinosa Kernel oil, Butyrospermum Parkii (shea butter) extract), and saccharide isomerate after fractional CO2 laser procedure: split-face, double blinded, randomized controlled trial](https://pubmed.ncbi.nlm.nih.gov/41134387/) Butyrospermum parkii butter shea butter · Lasers in Medical Science, 2025
- [Targeting Circadian Rhythm for the Regulation of Skin Collagen Metabolism](https://pubmed.ncbi.nlm.nih.gov/41527525/) Palmitoyl tripeptide-1 · Journal of Cosmetic Dermatology, 2026

## The brands

- German skincare: [Sebamed](https://lovi.care/skincare/ae/brands/sebamed)
- Spanish skincare: [Natura Bissé](https://lovi.care/skincare/ae/brands/natura-bisse)

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- [CeraVe vs Sebamed](https://lovi.care/skincare/ae/compare/cerave-vs-sebamed)
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- [La Roche-Posay vs Sebamed](https://lovi.care/skincare/ae/compare/la-roche-posay-vs-sebamed)
- [La Roche-Posay vs Natura Bissé](https://lovi.care/skincare/ae/compare/la-roche-posay-vs-natura-bisse)
- [Dr. Althea vs Sebamed](https://lovi.care/skincare/ae/compare/dr-althea-vs-sebamed)
- [Dr. Althea vs Natura Bissé](https://lovi.care/skincare/ae/compare/dr-althea-vs-natura-bisse)
- [Some By Mi vs Sebamed](https://lovi.care/skincare/ae/compare/some-by-mi-vs-sebamed)
- [Some By Mi vs Natura Bissé](https://lovi.care/skincare/ae/compare/some-by-mi-vs-natura-bisse)

## About the Lovi Fit

Lovi: Unbiased, science-based skincare AI trained on real user outcomes.

Lovi compares products by their fit scores, calculated from the full ingredient list with brand-independent rules its dermatologists and cosmetic chemists build and review, and personalizes every pick with AI trained on the real results of millions of users. Lovi trains its fit score models on a proprietary dataset built from more than 10,000 expert-labeled products and more than 100,000 simulated examples, following an internally consistent methodology presented at Cosmoprof, AMWC, and Skin of Color Update. Levels from best to worst: Superior, High, Average, Low, Caution, Warning.

Behind this comparison: Nadia Kapleva, MS (Co-founder, Medical Director); Alexey Shagraev, PhD (Co-founder, CEO and CTO); Dr. Sofía Perea Pérez, MD, MSc (Medical Board); Aishani Shah, MD (Medical Board); Asya Zubkova, MS (Medical Board); Hanna Kurets, MD (Medical Board, Medical Advisor); Elina Nazarenko, MD (Medical Board); Victoria Derkova, MS (Medical Board).

Page built Nov 8, 2026.

More from Lovi: https://lovi.care/skincare/llms.txt

## This page in other countries

- United States: https://lovi.care/skincare/compare/sebamed-vs-natura-bisse
- United Kingdom: https://lovi.care/skincare/uk/compare/sebamed-vs-natura-bisse
- Ireland: https://lovi.care/skincare/ie/compare/sebamed-vs-natura-bisse
- Germany: https://lovi.care/skincare/de/compare/sebamed-vs-natura-bisse
- France: https://lovi.care/skincare/fr/compare/sebamed-vs-natura-bisse
- Italy: https://lovi.care/skincare/it/compare/sebamed-vs-natura-bisse
- Netherlands: https://lovi.care/skincare/nl/compare/sebamed-vs-natura-bisse
- Spain: https://lovi.care/skincare/es/compare/sebamed-vs-natura-bisse
- Canada: https://lovi.care/skincare/ca/compare/sebamed-vs-natura-bisse
- Australia: https://lovi.care/skincare/au/compare/sebamed-vs-natura-bisse
- Singapore: https://lovi.care/skincare/sg/compare/sebamed-vs-natura-bisse
- Saudi Arabia: https://lovi.care/skincare/sa/compare/sebamed-vs-natura-bisse
- United Arab Emirates: https://lovi.care/skincare/ae/compare/sebamed-vs-natura-bisse (this page)