# RoC vs Sesderma

Page: https://lovi.care/skincare/ae/compare/roc-vs-sesderma

The Lovi Fit is the same in every country; only the stores and prices differ, and the ones here are for the United Arab Emirates.

RoC and Sesderma are distinguished skincare brands rooted in decades of dermatological heritage, with the French pioneer celebrated for expertly formulated [serums](https://lovi.care/skincare/ae/ingredients/serum), eye products, moisturizers, and cleansers enriched with [glycerin](https://lovi.care/skincare/ae/ingredients/glycerin) and [retinol](https://lovi.care/skincare/ae/ingredients/retinol), while the Spanish house is beloved for its advanced serums and meticulously engineered formulas. The former brand suits mature skin and skin with dark spots best, whereas the latter suits sensitive, hyperpigmented, and aging skin types best. Both brands differ largely in their ingredient philosophies and regional origins, offering targeted solutions such as glycerin to increase skin hydration and barrier function, and botanical [extracts](https://lovi.care/skincare/ae/ingredients/extract) to refine skin texture and promote a radiant complexion.

RoC is a French skincare brand founded in 1957 and owned by Bridgepoint Group plc since 2024.

[en.wikipedia.org](https://en.wikipedia.org/wiki/Bridgepoint_Group) [prnewswire.com](https://www.prnewswire.com/news-releases/roc-skincare-celebrates-sixth-annual-national-retinol-day-with-appointment-of-first-ever-chief-dermatologist-and-triple-serum-innovation-302931563.html) [beautymatter.com](https://beautymatter.com/articles/bridgepoint-to-acquire-roc-skincare)

Sesderma is a Spanish skincare brand founded in 1989 and owned by Grupo Sesderma since 2026.

[skinexpert.sesderma.com](https://skinexpert.sesderma.com/en/jb-capital-joins-the-shareholding-of-sesderma-group-as-a-strategic-partner/) [sesderma.com](https://www.sesderma.com/us_en/about-us.html)

This page compares some of the most popular RoC and Sesderma products; for every product of both brands, with a fit score for your own skin, [use the Lovi app](https://app.pora.ai/vqqJ/j1xj2b6o?af_sub2=compare&af_sub3=selection_note&af_sub4=pg994c6d3ef2).

### Popular RoC vs Sesderma products

#### Sesderma

- [Azelac RU Serum](https://lovi.care/skincare/ae/p/sesderma/azelac-ru-serum/for/acne-prone-skin) — High fit — [AED 123.63 at Amazon](https://www.amazon.ae/dp/B00987RKWW?tag=lovi00-21&linkCode=osi&th=1&psc=1)

#### RoC

- [Retinol Correxion Deep Wrinkle Night Cream](https://lovi.care/skincare/ae/p/roc/retinol-correxion-deep-wrinkle-night-cream/for/dark-spots) — High fit — [AED 129.48 at Amazon](https://www.amazon.ae/dp/B00027DMI8?tag=lovi00-21&linkCode=osi&th=1&psc=1)
- [Retinol Correxion Line Smoothing Eye Cream](https://lovi.care/skincare/ae/p/roc/retinol-correxion-line-smoothing-eye-cream/for/mature-skin) — High fit — [AED 90.00 at Amazon](https://www.amazon.ae/dp/B08GGD7NRN?tag=lovi00-21&linkCode=osi&th=1&psc=1)
- [Retinol Correxion Deep Wrinkle Serum](https://lovi.care/skincare/ae/p/roc/retinol-correxion-deep-wrinkle-serum/for/oily-skin) — Average fit — [AED 71.31 at Amazon](https://www.amazon.ae/dp/B0GQZ5J61H?tag=lovi00-21&linkCode=osi&th=1&psc=1)
- [Retinol Correxion Line Smoothing Max Hydration Cream](https://lovi.care/skincare/ae/p/roc/retinol-correxion-line-smoothing-max-hydration-cream/for/mature-skin) — High fit — [AED 137.29 at Amazon](https://www.amazon.ae/dp/B0744JV661?tag=lovi00-21&linkCode=osi&th=1&psc=1)
- [Derm Correxion Fill + Treat Serum](https://lovi.care/skincare/ae/p/roc/derm-correxion-fill-treat-serum/for/mature-skin) — Average fit
- [Multi Correxion Revive + Glow Daily Serum](https://lovi.care/skincare/ae/p/roc/multi-correxion-revive-glow-daily-serum/for/mature-skin) — High fit — [AED 137.25 at Amazon](https://www.amazon.ae/dp/B088C7S4VL?tag=lovi00-21&linkCode=osi&th=1&psc=1)
- [Derm Correxion Dual Eye Cream](https://lovi.care/skincare/ae/p/roc/derm-correxion-dual-eye-cream/for/mature-skin) — High fit
- [Multi Correxion Hydrate + Plump Eye Cream](https://lovi.care/skincare/ae/p/roc/multi-correxion-hydrate-plump-eye-cream/for/mature-skin) — High fit

### RoC vs Sesderma [serums](https://lovi.care/skincare/ae/ingredients/serum) and treatments

#### Sesderma

- [Azelac RU Serum](https://lovi.care/skincare/ae/p/sesderma/azelac-ru-serum/for/acne-prone-skin) — High fit — [AED 123.63 at Amazon](https://www.amazon.ae/dp/B00987RKWW?tag=lovi00-21&linkCode=osi&th=1&psc=1)

#### RoC

- [Retinol Correxion Deep Wrinkle Night Cream](https://lovi.care/skincare/ae/p/roc/retinol-correxion-deep-wrinkle-night-cream/for/dark-spots) — High fit — [AED 129.48 at Amazon](https://www.amazon.ae/dp/B00027DMI8?tag=lovi00-21&linkCode=osi&th=1&psc=1)
- [Retinol Correxion Deep Wrinkle Serum](https://lovi.care/skincare/ae/p/roc/retinol-correxion-deep-wrinkle-serum/for/oily-skin) — Average fit — [AED 71.31 at Amazon](https://www.amazon.ae/dp/B0GQZ5J61H?tag=lovi00-21&linkCode=osi&th=1&psc=1)
- [Derm Correxion Fill + Treat Serum](https://lovi.care/skincare/ae/p/roc/derm-correxion-fill-treat-serum/for/mature-skin) — Average fit
- [Multi Correxion Revive + Glow Daily Serum](https://lovi.care/skincare/ae/p/roc/multi-correxion-revive-glow-daily-serum/for/mature-skin) — High fit — [AED 137.25 at Amazon](https://www.amazon.ae/dp/B088C7S4VL?tag=lovi00-21&linkCode=osi&th=1&psc=1)
- [Derm Correxion Contour Cream](https://lovi.care/skincare/ae/p/roc/derm-correxion-contour-cream/for/mature-skin) — High fit
- [Daily Resurfacing Disks](https://lovi.care/skincare/ae/p/roc/daily-resurfacing-disks/for/acne-prone-skin) — Average fit — [AED 73.48 at Amazon](https://www.amazon.ae/dp/B005I2MP62?tag=lovi00-21&linkCode=osi&th=1&psc=1)

## Questions and answers

### RoC or Sesderma: which is better?

RoC is better for offering a wider variety of products on this page across multiple categories like cleansers, moisturizers, and sunscreens, while Sesderma features only a single [serum](https://lovi.care/skincare/ae/ingredients/serum). Reviewers note that RoC helps reduce wrinkles and fine lines, though some mention skin irritation and burning.

[The Journal of Investigative Dermatology, 2000](https://pubmed.ncbi.nlm.nih.gov/10692106/) [Archives of Dermatology, 2007](https://pubmed.ncbi.nlm.nih.gov/17515510/)

### What is the difference between RoC and Sesderma?

RoC features a wide range of products including cleansers, sunscreens, and [retinol](https://lovi.care/skincare/ae/ingredients/retinol) treatments that help reduce wrinkles, while Sesderma currently presents a single serum focused on dark spots and acne-prone skin. Retinol helps stimulate [collagen](https://lovi.care/skincare/ae/ingredients/collagen) accumulation in naturally aged human skin.

[The Journal of Investigative Dermatology, 2000](https://pubmed.ncbi.nlm.nih.gov/10692106/)

### Which is more affordable, RoC or Sesderma?

When it comes to value, reviewers on this page sometimes note that RoC products offer good value, while the page has no pricing or value mentions for Sesderma.

### Which causes fewer breakouts, RoC or Sesderma?

For acne-prone skin, the products on this page for RoC have a High fit with the BARRIER RENEW GEL-TO-FOAM CLEANSER and BARRIER RENEW AM MOISTURIZER [SPF 30](https://lovi.care/skincare/ae/ingredients/spf-30), whereas Sesderma's Azelac RU Serum also has a High fit.

### Which brand was founded earlier, RoC or Sesderma, and in which countries were they established?

RoC was founded earlier than Sesderma, having been established in France in 1957 while Sesderma was founded in Spain in 1989.

### How many products from RoC contain fragrance compared to Sesderma?

Ten out of twelve RoC products on this page list no fragrance while two contain it, whereas the single Sesderma product on this page includes fragrance.

### What skin types does the Sesderma Azelac RU Serum have a High fit level for?

On this page, the Sesderma Azelac RU Serum has a High fit level for acne-prone skin, skin with dark spots, and combination skin.

## Research behind their key ingredients

- [Vitamin A antagonizes decreased cell growth and elevated collagen-degrading matrix metalloproteinases and stimulates collagen accumulation in naturally aged human skin](https://pubmed.ncbi.nlm.nih.gov/10692106/) Retinol · The Journal of Investigative Dermatology, 2000
- [The effect of niacinamide on reducing cutaneous pigmentation and suppression of melanosome transfer](https://pubmed.ncbi.nlm.nih.gov/12100180/) Niacinamide · The British Journal of Dermatology, 2002
- [Green tea polyphenol (-)-epigallocatechin-3-gallate treatment of human skin inhibits ultraviolet radiation-induced oxidative stress](https://pubmed.ncbi.nlm.nih.gov/11181450/) Camellia sinensis extract · Carcinogenesis, 2001
- [Benefits of topical hyaluronic acid for skin quality and signs of skin aging: From literature review to clinical evidence](https://pubmed.ncbi.nlm.nih.gov/36200921/) Sodium hyaluronate · Dermatologic Therapy, 2022
- [Topical use of dexpanthenol in skin disorders](https://pubmed.ncbi.nlm.nih.gov/12113650/) Panthenol · American Journal of Clinical Dermatology, 2002
- [Cutaneous photoprotection from ultraviolet injury by green tea polyphenols](https://pubmed.ncbi.nlm.nih.gov/11209110/) Camellia sinensis extract · Journal of the American Academy of Dermatology, 2001
- [Improvement of naturally aged skin with vitamin A (retinol)](https://pubmed.ncbi.nlm.nih.gov/17515510/) Retinol · Archives of Dermatology, 2007
- [Quercitrin protects skin from UVB-induced oxidative damage](https://pubmed.ncbi.nlm.nih.gov/23545178/) Polygonum aviculare extract · Toxicology and Applied Pharmacology, 2013
- [Nicotinic acid/niacinamide and the skin](https://pubmed.ncbi.nlm.nih.gov/17147561/) Niacin · Journal of Cosmetic Dermatology, 2004
- [Anti-aging and brightening effects of a topical treatment containing vitamin C, vitamin E, and raspberry leaf cell culture extract: A split-face, randomized controlled trial](https://pubmed.ncbi.nlm.nih.gov/31975502/) Ascorbic acid, Tocopherol · Journal of Cosmetic Dermatology, 2020
- [Molecular basis of retinol anti-ageing properties in naturally aged human skin in vivo](https://pubmed.ncbi.nlm.nih.gov/27261203/) Retinol · International Journal of Cosmetic Science, 2017
- [Prospective, randomized, double-blind assessment of topical bakuchiol and retinol for facial photoageing](https://pubmed.ncbi.nlm.nih.gov/29947134/) Retinol · The British Journal of Dermatology, 2019
- [Alteration of barrier properties, stratum corneum ceramides and microbiome composition in response to lotion application on cosmetic dry skin](https://pubmed.ncbi.nlm.nih.gov/35340018/) Ceramides · Scientific Reports, 2022
- [Vitamin C mesotherapy versus topical application for gingival hyperpigmentation: a clinical and histopathological study](https://pubmed.ncbi.nlm.nih.gov/33966113/) Ascorbic acid · Clinical Oral Investigations, 2021
- [Ceramide 1 and ceramide 3 act synergistically on skin hydration and the transepidermal water loss of sodium lauryl sulfate-irritated skin](https://pubmed.ncbi.nlm.nih.gov/18717861/) Ceramide np · International Journal of Dermatology, 2008
- [Effect of a topical antioxidant serum containing vitamin C, vitamin E, and ferulic acid after Q-switched 1064-nm Nd:YAG laser for treatment of environment-induced skin pigmentation](https://pubmed.ncbi.nlm.nih.gov/32052907/) Ascorbic acid, Tocopherol · Journal of Cosmetic Dermatology, 2020
- [Green tea extract reduces induction of p53 and apoptosis in UVB-irradiated human skin independent of transcriptional controls](https://pubmed.ncbi.nlm.nih.gov/18631247/) Camellia sinensis leaf extract · Experimental Dermatology, 2009
- [Efficacy and Safety of Azelaic Acid Nanocrystal-Loaded In Situ Hydrogel in the Treatment of Acne Vulgaris](https://pubmed.ncbi.nlm.nih.gov/33923739/) Azelaic acid · Pharmaceutics, 2021
- [A topical lipophilic niacin derivative increases NAD, epidermal differentiation and barrier function in photodamaged skin](https://pubmed.ncbi.nlm.nih.gov/17518989/) Niacin · Experimental Dermatology, 2007
- [The 24-hour skin hydration and barrier function effects of a hyaluronic 1%, glycerin 5%, and Centella asiatica stem cells extract moisturizing fluid: an intra-subject, randomized, assessor-blinded study](https://pubmed.ncbi.nlm.nih.gov/28860834/) Glycerin · Clinical, Cosmetic and Investigational Dermatology, 2017
- [Encapsulation and controlled release of retinol from silicone particles for topical delivery](https://pubmed.ncbi.nlm.nih.gov/29604311/) Advanced retinol · Journal of Controlled Release, 2018
- [Microneedling by dermapen and glycolic acid peel for the treatment of acne scars: Comparative study](https://pubmed.ncbi.nlm.nih.gov/30548170/) Glycolic acid · Journal of Cosmetic Dermatology, 2019
- [A new topical panthenol-containing emollient: Results from two randomized controlled studies assessing its skin moisturization and barrier restoration potential, and the effect on skin microflora](https://pubmed.ncbi.nlm.nih.gov/27425824/) Panthenol · The Journal of Dermatological Treatment, 2017
- [Adenosine-loaded dissolving microneedle patches to improve skin wrinkles, dermal density, elasticity and hydration](https://pubmed.ncbi.nlm.nih.gov/29574973/) Adenosine · International Journal of Cosmetic Science, 2018
- [Efficacy of a topical gel containing chitosan, chlorhexidine, allantoin and dexpanthenol for pain and inflammation control after third molar surgery: A randomized and placebo-controlled clinical trial](https://pubmed.ncbi.nlm.nih.gov/32683390/) Panthenol, Allantoin · Medicina Oral, Patologia Oral Y Cirugia Bucal, 2020
- [Evaluation of dermal extracellular matrix and epidermal-dermal junction modifications using matrix-assisted laser desorption/ionization mass spectrometric imaging, in vivo reflectance confocal microscopy, echography, and histology: effect of age and peptide applications](https://pubmed.ncbi.nlm.nih.gov/25817264/) Palmitoyl tripeptide-1 · Journal of Cosmetic Dermatology, 2015
- [A Lipid Mixture Enriched by Ceramide NP with Fatty Acids of Diverse Chain Lengths Contributes to Restore the Skin Barrier Function Impaired by Topical Corticosteroid](https://pubmed.ncbi.nlm.nih.gov/34348350/) Ceramide np · Skin Pharmacology and Physiology, 2022
- [Effects of 15% Azelaic Acid Gel in the Management of Post-Inflammatory Erythema and Post-Inflammatory Hyperpigmentation in Acne Vulgaris](https://pubmed.ncbi.nlm.nih.gov/38734843/) Azelaic acid · Dermatology and Therapy, 2024
- [Effects of 1,3-propanediol associated, or not, with butylene glycol and/or glycerol on skin hydration and skin barrier function](https://pubmed.ncbi.nlm.nih.gov/37699769/) Propanediol · International Journal of Cosmetic Science, 2024
- [Subclinical cutaneous inflammation remained after permeability barrier disruption enhances UV sensitivity by altering ER stress responses and topical pseudoceramide prevents them](https://pubmed.ncbi.nlm.nih.gov/28631090/) Ceramide ng · Archives of Dermatological Research, 2017
- [Antiacne and antiblotch activities of a formulated combination of Aloe barbadensis leaf powder, Garcinia mangostana peel extract, and Camellia sinensis leaf extract](https://pubmed.ncbi.nlm.nih.gov/31239743/) Camellia sinensis leaf extract · Clinical, Cosmetic and Investigational Dermatology, 2019
- [Clinical evaluation of the efficacy of a facial serum containing dioic acid, glycolic acid, salicylic acid, LHA, citric acid, and HEPES in treating post-inflammatory hyperchromia and controlling oily skin in patients with acne vulgaris](https://pubmed.ncbi.nlm.nih.gov/33617668/) Citric acid · Journal of Cosmetic Dermatology, 2021
- [Exploring the Therapeutic Potential of Green Tea (Camellia sinensis L.) in Anti-Aging: A Comprehensive Review of Mechanisms and Findings](https://pubmed.ncbi.nlm.nih.gov/39377377/) Camellia sinensis extract · Mini Reviews in Medicinal Chemistry, 2025
- [Clinical Development and Evaluation of a Multi-Component Dissolving Microneedle Patch for Skin Pigmentation Disorders](https://pubmed.ncbi.nlm.nih.gov/37571190/) 3-o-ethyl ascorbic acid · Polymers, 2023
- [Two-phase delivery using a horse oil and adenosine-loaded dissolving microneedle patch for skin barrier restoration, moisturization, and wrinkle improvement](https://pubmed.ncbi.nlm.nih.gov/30160014/) Adenosine · Journal of Cosmetic Dermatology, 2019
- [Redefining face contour with a novel anti-aging cosmetic product: an open-label, prospective clinical study](https://pubmed.ncbi.nlm.nih.gov/29180884/) Alteromonas extract ferment · Clinical, Cosmetic and Investigational Dermatology, 2017
- [Squalane as a Promising Agent Protecting UV-Induced Inhibition of Collagen Biosynthesis and Wound Healing in Human Dermal Fibroblast](https://pubmed.ncbi.nlm.nih.gov/40363772/) Squalane · Molecules, 2025
- [Epigallocatechin Gallate Enzymatic Alpha Glucosylation Potentiates Its Skin-Lightening Activity-Involvement of Skin Microbiota](https://pubmed.ncbi.nlm.nih.gov/39598779/) Camellia sinensis leaf extract · Molecules, 2024
- [A randomized controlled trial to compare the effectiveness and safety of adsorbent lotion containing tapioca starch, spent grain wax, Butyrospermum parkii extract, argania spinosa kernel oil, aloe barbadensis, rosehip oil, and allantoin with a low-potency topical corticosteroid in the treatment of intertrigo](https://pubmed.ncbi.nlm.nih.gov/33811776/) Shea butter · Journal of Cosmetic Dermatology, 2022
- [Influence of vitamin E acetate on stratum corneum hydration](https://pubmed.ncbi.nlm.nih.gov/9706379/) Tocopheryl acetate · Arzneimittel-Forschung, 1998
- [Evaluation of the Efficacy and Safety of a Panthenol-Enriched Mask for Skin Barrier Recovery After Facial Laser Treatment: Results of a Double-Blind Randomized Controlled Study](https://pubmed.ncbi.nlm.nih.gov/40613435/) Panthenol · Journal of Cosmetic Dermatology, 2025
- [Antioxidant and membrane-protective effects of the 3-O-ethyl ascorbic acid-cannabigerol system on UVB-irradiated human keratinocytes](https://pubmed.ncbi.nlm.nih.gov/39778604/) 3-o-ethyl ascorbic acid · Free Radical Biology & Medicine, 2025
- [TiO2-embedded mesoporous silica with lower porosity is beneficial to adsorb the pollutants and retard UV filter absorption: A possible application for outdoor skin protection](https://pubmed.ncbi.nlm.nih.gov/36455708/) Avobenzone · European Journal of Pharmaceutical Sciences, 2023
- [Study of the soothing effects of troxerutin in alleviating skin sensitivity](https://pubmed.ncbi.nlm.nih.gov/38720512/) Troxerutin · Journal of Cosmetic Dermatology, 2024
- [Thermostable hyaluronic acid-based dissolving microneedles with high-loading capacity: design, optimization, and transdermal delivery of anti-aging ingredients](https://pubmed.ncbi.nlm.nih.gov/41628877/) 3-o-ethyl ascorbic acid · International Journal of Biological Macromolecules, 2026
- [Translational Evaluation of a Disodium Adenosine Monophosphate (AMP2Na)-Based Topical Formulation for Physiology-Aligned Skin Rejuvenation: Integrated In Vitro, Ex Vivo, and Clinical Evidence](https://pubmed.ncbi.nlm.nih.gov/42278371/) Adenosine · International Journal of Molecular Sciences, 2026
- [Nanostructured Lipid Carrier Based Gel Containing α-Tocopherol and α-Tocopheryl Acetate for Synergistic Cutaneous Antiaging Efficacy](https://pubmed.ncbi.nlm.nih.gov/41309687/) Tocopheryl acetate · Scientific Reports, 2025
- [Safety assessment on comedogenicity of dermatological products containing d-alpha tocopheryl acetate in Asian subjects: A double-blind randomized controlled trial](https://pubmed.ncbi.nlm.nih.gov/34471722/) Tocopheryl acetate · Contemporary Clinical Trials Communications, 2021
- [The efficacy of enoxolone in reducing erythema and pain after laser treatment: A randomized split-face pilot study](https://pubmed.ncbi.nlm.nih.gov/38622995/) Glycyrrhetinic acid · Journal of Cosmetic Dermatology, 2024
- [Targeting Circadian Rhythm for the Regulation of Skin Collagen Metabolism](https://pubmed.ncbi.nlm.nih.gov/41527525/) Palmitoyl tripeptide-1 · Journal of Cosmetic Dermatology, 2026
- [Efficacy and safety of combination cream of stimu-tex AS™ (spent grain wax, Argania Spinosa Kernel oil, Butyrospermum Parkii (shea butter) extract), and saccharide isomerate after fractional CO2 laser procedure: split-face, double blinded, randomized controlled trial](https://pubmed.ncbi.nlm.nih.gov/41134387/) Shea butter · Lasers in Medical Science, 2025

## The brands

- French skincare: [RoC](https://lovi.care/skincare/ae/brands/roc)
- Spanish skincare: [Sesderma](https://lovi.care/skincare/ae/brands/sesderma)

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## About the Lovi Fit

Lovi: Unbiased, science-based skincare AI trained on real user outcomes.

Lovi compares products by their fit scores, calculated from the full ingredient list with brand-independent rules its dermatologists and cosmetic chemists build and review, and personalizes every pick with AI trained on the real results of millions of users. Lovi trains its fit score models on a proprietary dataset built from more than 10,000 expert-labeled products and more than 100,000 simulated examples, following an internally consistent methodology presented at Cosmoprof, AMWC, and Skin of Color Update. Levels from best to worst: Superior, High, Average, Low, Caution, Warning.

Behind this comparison: Nadia Kapleva, MS (Co-founder, Medical Director); Alexey Shagraev, PhD (Co-founder, CEO and CTO); Dr. Sofía Perea Pérez, MD, MSc (Medical Board); Aishani Shah, MD (Medical Board); Asya Zubkova, MS (Medical Board); Hanna Kurets, MD (Medical Board, Medical Advisor); Elina Nazarenko, MD (Medical Board); Victoria Derkova, MS (Medical Board).

Page built Nov 8, 2026.

More from Lovi: https://lovi.care/skincare/llms.txt

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