# RoC vs Mesoestetic

Page: https://lovi.care/skincare/ae/compare/roc-vs-mesoestetic

The Lovi Fit is the same in every country; only the stores and prices differ, and the ones here are for the United Arab Emirates.

RoC and Mesoestetic are European skincare brands founded in France in 1957 and Spain in 1984, respectively. Both are beloved for expertly formulated [serums](https://lovi.care/skincare/ae/ingredients/serum) and targeted solutions that suit mature skin best. While the French brand is also known for moisturizers, cleansers, and eye products enriched with [glycerin](https://lovi.care/skincare/ae/ingredients/glycerin) and [retinol](https://lovi.care/skincare/ae/ingredients/retinol), the Spanish brand is known for meticulously crafted formulas that suit sensitive and uneven skin. They differ in their key offerings, as the former utilizes glycerin and retinol to increase hydration and reduce fine wrinkles, whereas the latter elevates daily routines with gentle yet rigorous compositions like the Cosmelan 2.

RoC is a French skincare brand founded in 1957 and owned by Bridgepoint Group plc since 2024.

[en.wikipedia.org](https://en.wikipedia.org/wiki/Bridgepoint_Group) [prnewswire.com](https://www.prnewswire.com/news-releases/roc-skincare-celebrates-sixth-annual-national-retinol-day-with-appointment-of-first-ever-chief-dermatologist-and-triple-serum-innovation-302931563.html) [beautymatter.com](https://beautymatter.com/articles/bridgepoint-to-acquire-roc-skincare)

Mesoestetic is a Spanish skincare brand founded in 1984 and owned by Mesoestetic Pharma Group, S.L..

[mesoestetic.com](https://www.mesoestetic.com/about-us) [tracxn.com](https://tracxn.com/d/companies/mesoestetic/__1eAnF7uALQzHII_So8HqZbHfSUJuilusj9hTisrG0tk)

This page compares some of the most popular RoC and Mesoestetic products; for every product of both brands, with a fit score for your own skin, [use the Lovi app](https://app.pora.ai/vqqJ/j1xj2b6o?af_sub2=compare&af_sub3=selection_note&af_sub4=pg60399f470b).

### Popular RoC vs Mesoestetic products

#### RoC

- [Retinol Correxion Deep Wrinkle Night Cream](https://lovi.care/skincare/ae/p/roc/retinol-correxion-deep-wrinkle-night-cream/for/dark-spots) — High fit — [AED 129.48 at Amazon](https://www.amazon.ae/dp/B00027DMI8?tag=lovi00-21&linkCode=osi&th=1&psc=1)
- [Retinol Correxion Line Smoothing Eye Cream](https://lovi.care/skincare/ae/p/roc/retinol-correxion-line-smoothing-eye-cream/for/mature-skin) — High fit — [AED 90.00 at Amazon](https://www.amazon.ae/dp/B08GGD7NRN?tag=lovi00-21&linkCode=osi&th=1&psc=1)
- [Retinol Correxion Deep Wrinkle Serum](https://lovi.care/skincare/ae/p/roc/retinol-correxion-deep-wrinkle-serum/for/oily-skin) — Average fit — [AED 71.31 at Amazon](https://www.amazon.ae/dp/B0GQZ5J61H?tag=lovi00-21&linkCode=osi&th=1&psc=1)
- [Retinol Correxion Line Smoothing Max Hydration Cream](https://lovi.care/skincare/ae/p/roc/retinol-correxion-line-smoothing-max-hydration-cream/for/mature-skin) — High fit — [AED 137.29 at Amazon](https://www.amazon.ae/dp/B0744JV661?tag=lovi00-21&linkCode=osi&th=1&psc=1)
- [Derm Correxion Fill + Treat Serum](https://lovi.care/skincare/ae/p/roc/derm-correxion-fill-treat-serum/for/mature-skin) — Average fit
- [Multi Correxion Revive + Glow Daily Serum](https://lovi.care/skincare/ae/p/roc/multi-correxion-revive-glow-daily-serum/for/mature-skin) — High fit — [AED 137.25 at Amazon](https://www.amazon.ae/dp/B088C7S4VL?tag=lovi00-21&linkCode=osi&th=1&psc=1)
- [Derm Correxion Dual Eye Cream](https://lovi.care/skincare/ae/p/roc/derm-correxion-dual-eye-cream/for/mature-skin) — High fit
- [Multi Correxion Hydrate + Plump Eye Cream](https://lovi.care/skincare/ae/p/roc/multi-correxion-hydrate-plump-eye-cream/for/mature-skin) — High fit

#### Mesoestetic

- [Cosmelan 2](https://lovi.care/skincare/ae/p/mesoestetic/cosmelan-2/for/acne-prone-skin) — Average fit

### RoC vs Mesoestetic [serums](https://lovi.care/skincare/ae/ingredients/serum) and treatments

#### Mesoestetic

- [Cosmelan 2](https://lovi.care/skincare/ae/p/mesoestetic/cosmelan-2/for/acne-prone-skin) — Average fit

#### RoC

- [Retinol Correxion Deep Wrinkle Night Cream](https://lovi.care/skincare/ae/p/roc/retinol-correxion-deep-wrinkle-night-cream/for/dark-spots) — High fit — [AED 129.48 at Amazon](https://www.amazon.ae/dp/B00027DMI8?tag=lovi00-21&linkCode=osi&th=1&psc=1)
- [Retinol Correxion Deep Wrinkle Serum](https://lovi.care/skincare/ae/p/roc/retinol-correxion-deep-wrinkle-serum/for/oily-skin) — Average fit — [AED 71.31 at Amazon](https://www.amazon.ae/dp/B0GQZ5J61H?tag=lovi00-21&linkCode=osi&th=1&psc=1)
- [Derm Correxion Fill + Treat Serum](https://lovi.care/skincare/ae/p/roc/derm-correxion-fill-treat-serum/for/mature-skin) — Average fit
- [Multi Correxion Revive + Glow Daily Serum](https://lovi.care/skincare/ae/p/roc/multi-correxion-revive-glow-daily-serum/for/mature-skin) — High fit — [AED 137.25 at Amazon](https://www.amazon.ae/dp/B088C7S4VL?tag=lovi00-21&linkCode=osi&th=1&psc=1)
- [Derm Correxion Contour Cream](https://lovi.care/skincare/ae/p/roc/derm-correxion-contour-cream/for/mature-skin) — High fit
- [Daily Resurfacing Disks](https://lovi.care/skincare/ae/p/roc/daily-resurfacing-disks/for/acne-prone-skin) — Average fit — [AED 73.48 at Amazon](https://www.amazon.ae/dp/B005I2MP62?tag=lovi00-21&linkCode=osi&th=1&psc=1)

## Questions and answers

### RoC or Mesoestetic: which is better?

RoC is better for a wider variety of skin types, since the products on this page achieve a High Lovi fit for mature skin, skin with dark spots, and acne-prone skin, whereas Mesoestetic only achieves an Average fit for those skin types.

### What is the difference between RoC and Mesoestetic?

RoC offers a wide range of twelve products featuring key ingredients like [retinol](https://lovi.care/skincare/ae/ingredients/retinol) and [vitamin C](https://lovi.care/skincare/ae/ingredients/vitamin-c) that fit mature skin, skin with dark spots, and acne-prone skin well, whereas Mesoestetic features only one product on this page, Cosmelan 2. RoC's products on this page help reduce wrinkles and fine lines, and retinol is shown to stimulate [collagen](https://lovi.care/skincare/ae/ingredients/collagen) accumulation in naturally aged human skin.

[The Journal of Investigative Dermatology, 2000](https://pubmed.ncbi.nlm.nih.gov/10692106/) [Archives of Dermatology, 2007](https://pubmed.ncbi.nlm.nih.gov/17515510/)

### Which is more affordable, RoC or Mesoestetic?

RoC offers better value for shoppers, with reviewers noting the brand's good value across a wide product selection.

### Which causes fewer breakouts, RoC or Mesoestetic?

When it comes to acne-prone skin, the products on this page by RoC feature high fit levels for cleansers like the Barrier Renew Gel-to-Foam Cleanser, whereas Mesoestetic has only average fit levels with Cosmelan 2. Reviewers of RoC also note benefits for reducing wrinkles and fine lines, though some report skin irritation and burning.

### How does the founding year and country of origin compare between RoC and Mesoestetic?

RoC was founded in 1957 in France, whereas Mesoestetic was founded later in 1984 in Spain.

### Which brand offers more fragrance-free products according to the page?

RoC offers more fragrance-free products on this page, with 10 out of 12 listing no fragrance.

### What are the main skin types that RoC fits best based on its routines?

Based on its brand-focused routines, the skin types that RoC fits best are mature skin, skin with dark spots, and acne-prone skin.

## Research behind their key ingredients

- [Vitamin A antagonizes decreased cell growth and elevated collagen-degrading matrix metalloproteinases and stimulates collagen accumulation in naturally aged human skin](https://pubmed.ncbi.nlm.nih.gov/10692106/) Retinol · The Journal of Investigative Dermatology, 2000
- [The effect of niacinamide on reducing cutaneous pigmentation and suppression of melanosome transfer](https://pubmed.ncbi.nlm.nih.gov/12100180/) Niacinamide · The British Journal of Dermatology, 2002
- [Green tea polyphenol (-)-epigallocatechin-3-gallate treatment of human skin inhibits ultraviolet radiation-induced oxidative stress](https://pubmed.ncbi.nlm.nih.gov/11181450/) Camellia sinensis extract · Carcinogenesis, 2001
- [Benefits of topical hyaluronic acid for skin quality and signs of skin aging: From literature review to clinical evidence](https://pubmed.ncbi.nlm.nih.gov/36200921/) Sodium hyaluronate · Dermatologic Therapy, 2022
- [Topical use of dexpanthenol in skin disorders](https://pubmed.ncbi.nlm.nih.gov/12113650/) Panthenol · American Journal of Clinical Dermatology, 2002
- [Cutaneous photoprotection from ultraviolet injury by green tea polyphenols](https://pubmed.ncbi.nlm.nih.gov/11209110/) Camellia sinensis extract · Journal of the American Academy of Dermatology, 2001
- [Improvement of naturally aged skin with vitamin A (retinol)](https://pubmed.ncbi.nlm.nih.gov/17515510/) Retinol · Archives of Dermatology, 2007
- [Quercitrin protects skin from UVB-induced oxidative damage](https://pubmed.ncbi.nlm.nih.gov/23545178/) Polygonum aviculare extract · Toxicology and Applied Pharmacology, 2013
- [Anti-aging and brightening effects of a topical treatment containing vitamin C, vitamin E, and raspberry leaf cell culture extract: A split-face, randomized controlled trial](https://pubmed.ncbi.nlm.nih.gov/31975502/) Ascorbic acid, Tocopherol · Journal of Cosmetic Dermatology, 2020
- [Molecular basis of retinol anti-ageing properties in naturally aged human skin in vivo](https://pubmed.ncbi.nlm.nih.gov/27261203/) Retinol · International Journal of Cosmetic Science, 2017
- [Prospective, randomized, double-blind assessment of topical bakuchiol and retinol for facial photoageing](https://pubmed.ncbi.nlm.nih.gov/29947134/) Retinol · The British Journal of Dermatology, 2019
- [Treatment of acne with a combination of propolis, tea tree oil, and Aloe vera compared to erythromycin cream: two double-blind investigations](https://pubmed.ncbi.nlm.nih.gov/30588129/) Aloe barbadensis leaf juice · Clinical Pharmacology, 2018
- [Alteration of barrier properties, stratum corneum ceramides and microbiome composition in response to lotion application on cosmetic dry skin](https://pubmed.ncbi.nlm.nih.gov/35340018/) Ceramides · Scientific Reports, 2022
- [Vitamin C mesotherapy versus topical application for gingival hyperpigmentation: a clinical and histopathological study](https://pubmed.ncbi.nlm.nih.gov/33966113/) Ascorbic acid · Clinical Oral Investigations, 2021
- [Ceramide 1 and ceramide 3 act synergistically on skin hydration and the transepidermal water loss of sodium lauryl sulfate-irritated skin](https://pubmed.ncbi.nlm.nih.gov/18717861/) Ceramide np · International Journal of Dermatology, 2008
- [Effect of a topical antioxidant serum containing vitamin C, vitamin E, and ferulic acid after Q-switched 1064-nm Nd:YAG laser for treatment of environment-induced skin pigmentation](https://pubmed.ncbi.nlm.nih.gov/32052907/) Ascorbic acid, Tocopherol · Journal of Cosmetic Dermatology, 2020
- [Tailoring of Retinyl Palmitate-Based Ethosomal Hydrogel as a Novel Nanoplatform for Acne Vulgaris Management: Fabrication, Optimization, and Clinical Evaluation Employing a Split-Face Comparative Study](https://pubmed.ncbi.nlm.nih.gov/34211271/) Retinyl palmitate · International Journal of Nanomedicine, 2021
- [Green tea extract reduces induction of p53 and apoptosis in UVB-irradiated human skin independent of transcriptional controls](https://pubmed.ncbi.nlm.nih.gov/18631247/) Camellia sinensis leaf extract · Experimental Dermatology, 2009
- [Efficacy and Safety of Azelaic Acid Nanocrystal-Loaded In Situ Hydrogel in the Treatment of Acne Vulgaris](https://pubmed.ncbi.nlm.nih.gov/33923739/) Azelaic acid · Pharmaceutics, 2021
- [The 24-hour skin hydration and barrier function effects of a hyaluronic 1%, glycerin 5%, and Centella asiatica stem cells extract moisturizing fluid: an intra-subject, randomized, assessor-blinded study](https://pubmed.ncbi.nlm.nih.gov/28860834/) Glycerin · Clinical, Cosmetic and Investigational Dermatology, 2017
- [Encapsulation and controlled release of retinol from silicone particles for topical delivery](https://pubmed.ncbi.nlm.nih.gov/29604311/) Advanced retinol · Journal of Controlled Release, 2018
- [Microneedling by dermapen and glycolic acid peel for the treatment of acne scars: Comparative study](https://pubmed.ncbi.nlm.nih.gov/30548170/) Glycolic acid · Journal of Cosmetic Dermatology, 2019
- [A new topical panthenol-containing emollient: Results from two randomized controlled studies assessing its skin moisturization and barrier restoration potential, and the effect on skin microflora](https://pubmed.ncbi.nlm.nih.gov/27425824/) Panthenol · The Journal of Dermatological Treatment, 2017
- [A Double-Blinded, Randomized, Vehicle-Controlled Study of the Efficacy of Moisturizer Containing Licochalcone A, Decanediol, L-Carnitine, and Salicylic Acid for Prevention of Acne Relapse in Asian Population](https://pubmed.ncbi.nlm.nih.gov/33150170/) Salicylic acid · BioMed Research International, 2020
- [Adenosine-loaded dissolving microneedle patches to improve skin wrinkles, dermal density, elasticity and hydration](https://pubmed.ncbi.nlm.nih.gov/29574973/) Adenosine · International Journal of Cosmetic Science, 2018
- [Efficacy of a topical gel containing chitosan, chlorhexidine, allantoin and dexpanthenol for pain and inflammation control after third molar surgery: A randomized and placebo-controlled clinical trial](https://pubmed.ncbi.nlm.nih.gov/32683390/) Panthenol, Allantoin · Medicina Oral, Patologia Oral Y Cirugia Bucal, 2020
- [Efficacy of a multitargeted, salicylic acid-based dermocosmetic cream compared to benzoyl peroxide 5% in Acne vulgaris: Results from a randomized study](https://pubmed.ncbi.nlm.nih.gov/37941097/) Salicylic acid · Journal of Cosmetic Dermatology, 2024
- [Evaluation of dermal extracellular matrix and epidermal-dermal junction modifications using matrix-assisted laser desorption/ionization mass spectrometric imaging, in vivo reflectance confocal microscopy, echography, and histology: effect of age and peptide applications](https://pubmed.ncbi.nlm.nih.gov/25817264/) Palmitoyl tripeptide-1 · Journal of Cosmetic Dermatology, 2015
- [A Lipid Mixture Enriched by Ceramide NP with Fatty Acids of Diverse Chain Lengths Contributes to Restore the Skin Barrier Function Impaired by Topical Corticosteroid](https://pubmed.ncbi.nlm.nih.gov/34348350/) Ceramide np · Skin Pharmacology and Physiology, 2022
- [Effects of 15% Azelaic Acid Gel in the Management of Post-Inflammatory Erythema and Post-Inflammatory Hyperpigmentation in Acne Vulgaris](https://pubmed.ncbi.nlm.nih.gov/38734843/) Azelaic acid · Dermatology and Therapy, 2024
- [A Salicylic Acid-Based Dermocosmetic is Effective as an Adjunct to Benzoyl Peroxide for Mild to Moderate Acne and as Monotherapy in Maintenance Post Benzoyl Peroxide](https://pubmed.ncbi.nlm.nih.gov/38051857/) Salicylic acid · Journal of Drugs in Dermatology, 2023
- [Effects of 1,3-propanediol associated, or not, with butylene glycol and/or glycerol on skin hydration and skin barrier function](https://pubmed.ncbi.nlm.nih.gov/37699769/) Propanediol · International Journal of Cosmetic Science, 2024
- [Subclinical cutaneous inflammation remained after permeability barrier disruption enhances UV sensitivity by altering ER stress responses and topical pseudoceramide prevents them](https://pubmed.ncbi.nlm.nih.gov/28631090/) Ceramide ng · Archives of Dermatological Research, 2017
- [Antiacne and antiblotch activities of a formulated combination of Aloe barbadensis leaf powder, Garcinia mangostana peel extract, and Camellia sinensis leaf extract](https://pubmed.ncbi.nlm.nih.gov/31239743/) Camellia sinensis leaf extract · Clinical, Cosmetic and Investigational Dermatology, 2019
- [Clinical evaluation of the efficacy of a facial serum containing dioic acid, glycolic acid, salicylic acid, LHA, citric acid, and HEPES in treating post-inflammatory hyperchromia and controlling oily skin in patients with acne vulgaris](https://pubmed.ncbi.nlm.nih.gov/33617668/) Citric acid · Journal of Cosmetic Dermatology, 2021
- [Exploring the Therapeutic Potential of Green Tea (Camellia sinensis L.) in Anti-Aging: A Comprehensive Review of Mechanisms and Findings](https://pubmed.ncbi.nlm.nih.gov/39377377/) Camellia sinensis extract · Mini Reviews in Medicinal Chemistry, 2025
- [Clinical Development and Evaluation of a Multi-Component Dissolving Microneedle Patch for Skin Pigmentation Disorders](https://pubmed.ncbi.nlm.nih.gov/37571190/) 3-o-ethyl ascorbic acid · Polymers, 2023
- [Two-phase delivery using a horse oil and adenosine-loaded dissolving microneedle patch for skin barrier restoration, moisturization, and wrinkle improvement](https://pubmed.ncbi.nlm.nih.gov/30160014/) Adenosine · Journal of Cosmetic Dermatology, 2019
- [Redefining face contour with a novel anti-aging cosmetic product: an open-label, prospective clinical study](https://pubmed.ncbi.nlm.nih.gov/29180884/) Alteromonas extract ferment · Clinical, Cosmetic and Investigational Dermatology, 2017
- [Squalane as a Promising Agent Protecting UV-Induced Inhibition of Collagen Biosynthesis and Wound Healing in Human Dermal Fibroblast](https://pubmed.ncbi.nlm.nih.gov/40363772/) Squalane · Molecules, 2025
- [Epigallocatechin Gallate Enzymatic Alpha Glucosylation Potentiates Its Skin-Lightening Activity-Involvement of Skin Microbiota](https://pubmed.ncbi.nlm.nih.gov/39598779/) Camellia sinensis leaf extract · Molecules, 2024
- [A randomized controlled trial to compare the effectiveness and safety of adsorbent lotion containing tapioca starch, spent grain wax, Butyrospermum parkii extract, argania spinosa kernel oil, aloe barbadensis, rosehip oil, and allantoin with a low-potency topical corticosteroid in the treatment of intertrigo](https://pubmed.ncbi.nlm.nih.gov/33811776/) Shea butter · Journal of Cosmetic Dermatology, 2022
- [Evaluation of the Efficacy and Safety of a Panthenol-Enriched Mask for Skin Barrier Recovery After Facial Laser Treatment: Results of a Double-Blind Randomized Controlled Study](https://pubmed.ncbi.nlm.nih.gov/40613435/) Panthenol · Journal of Cosmetic Dermatology, 2025
- [Antioxidant and membrane-protective effects of the 3-O-ethyl ascorbic acid-cannabigerol system on UVB-irradiated human keratinocytes](https://pubmed.ncbi.nlm.nih.gov/39778604/) 3-o-ethyl ascorbic acid · Free Radical Biology & Medicine, 2025
- [TiO2-embedded mesoporous silica with lower porosity is beneficial to adsorb the pollutants and retard UV filter absorption: A possible application for outdoor skin protection](https://pubmed.ncbi.nlm.nih.gov/36455708/) Avobenzone · European Journal of Pharmaceutical Sciences, 2023
- [Study of the soothing effects of troxerutin in alleviating skin sensitivity](https://pubmed.ncbi.nlm.nih.gov/38720512/) Troxerutin · Journal of Cosmetic Dermatology, 2024
- [Thermostable hyaluronic acid-based dissolving microneedles with high-loading capacity: design, optimization, and transdermal delivery of anti-aging ingredients](https://pubmed.ncbi.nlm.nih.gov/41628877/) 3-o-ethyl ascorbic acid · International Journal of Biological Macromolecules, 2026
- [Translational Evaluation of a Disodium Adenosine Monophosphate (AMP2Na)-Based Topical Formulation for Physiology-Aligned Skin Rejuvenation: Integrated In Vitro, Ex Vivo, and Clinical Evidence](https://pubmed.ncbi.nlm.nih.gov/42278371/) Adenosine · International Journal of Molecular Sciences, 2026
- [Targeting Circadian Rhythm for the Regulation of Skin Collagen Metabolism](https://pubmed.ncbi.nlm.nih.gov/41527525/) Palmitoyl tripeptide-1 · Journal of Cosmetic Dermatology, 2026
- [Efficacy and safety of combination cream of stimu-tex AS™ (spent grain wax, Argania Spinosa Kernel oil, Butyrospermum Parkii (shea butter) extract), and saccharide isomerate after fractional CO2 laser procedure: split-face, double blinded, randomized controlled trial](https://pubmed.ncbi.nlm.nih.gov/41134387/) Shea butter · Lasers in Medical Science, 2025

## The brands

- French skincare: [RoC](https://lovi.care/skincare/ae/brands/roc)
- Spanish skincare: [Mesoestetic](https://lovi.care/skincare/ae/brands/mesoestetic)

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## About the Lovi Fit

Lovi: Unbiased, science-based skincare AI trained on real user outcomes.

Lovi compares products by their fit scores, calculated from the full ingredient list with brand-independent rules its dermatologists and cosmetic chemists build and review, and personalizes every pick with AI trained on the real results of millions of users. Lovi trains its fit score models on a proprietary dataset built from more than 10,000 expert-labeled products and more than 100,000 simulated examples, following an internally consistent methodology presented at Cosmoprof, AMWC, and Skin of Color Update. Levels from best to worst: Superior, High, Average, Low, Caution, Warning.

Behind this comparison: Nadia Kapleva, MS (Co-founder, Medical Director); Alexey Shagraev, PhD (Co-founder, CEO and CTO); Dr. Sofía Perea Pérez, MD, MSc (Medical Board); Aishani Shah, MD (Medical Board); Asya Zubkova, MS (Medical Board); Hanna Kurets, MD (Medical Board, Medical Advisor); Elina Nazarenko, MD (Medical Board); Victoria Derkova, MS (Medical Board).

Page built Nov 8, 2026.

More from Lovi: https://lovi.care/skincare/llms.txt

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- United Arab Emirates: https://lovi.care/skincare/ae/compare/roc-vs-mesoestetic (this page)