Pair vs Sesderma
Pair and Sesderma are trusted skincare brands, featuring targeted and advanced serums with meticulously crafted formulas. The Japanese brand suits acne-prone skin best, featuring the Acne Cream W for stubborn blemishes, while the Spanish brand suits sensitive, hyperpigmented, and aging skin types best, featuring the Azelac RU Serum. Both brands help restore balance and clarity, though they differ in their specific botanical extracts and active compounds for radiant complexions.
Pair is a Japanese skincare brand founded in 2000 and owned by Lion Corporation since 2004.
ja.wikipedia.orgbeautymatter.com
Sesderma is a Spanish skincare brand founded in 1989 and owned by Grupo Sesderma since 2026.
skinexpert.sesderma.comsesderma.com
This page compares some of the most popular Pair and Sesderma products; for every product of both brands, with a fit score for your own skin, use the Lovi app.
Questions and answers
Pair or Sesderma: which is better?
Sesderma offers a High fit for acne-prone skin and skin with dark spots, whereas Pair provides an Average fit across these types. Lovi rates Sesderma's Azelac RU Serum with fragrance, while the products on this page from Pair list no fragrance.
What is the difference between Pair and Sesderma?
Sesderma Azelac RU Serum has a High Lovi fit for acne-prone skin and skin with dark spots, whereas Pair Acne Cream W has an Average fit for those skin types. Additionally, every product on this page by Pair lists no fragrance, while Sesderma includes fragrance in its serum.
Which is more affordable, Pair or Sesderma?
The page facts do not mention pricing or affordability for either Pair or Sesderma.
Which causes fewer breakouts, Pair or Sesderma?
Sesderma offers a high fit for acne-prone skin with its Azelac RU Serum, whereas Pair products on this page receive only average fits for acne-prone and oily skin-types.
Which brand has been established longer, Pair or Sesderma?
Sesderma has been established longer than Pair, having been founded in Spain in 1989 compared to Pair, which was founded in Japan in 2000.
Do products from Pair or Sesderma contain fragrance?
Pair products on this page list no fragrance in their ingredients, whereas Sesderma's Azelac RU Serum contains fragrance.
Which brand offers a serum that is rated High for skin with dark spots?
Sesderma offers Azelac RU Serum, which Lovi rates High for skin with dark spots.
Research behind their key ingredients
The effect of niacinamide on reducing cutaneous pigmentation and suppression of melanosome transfer
Molecular basis of retinol anti-ageing properties in naturally aged human skin in vivo
Behind this comparison
Lovi compares products by their fit scores, calculated from the full ingredient list with brand-independent rules our dermatologists and cosmetic chemists build and review, and personalizes every pick with AI trained on the real results of millions of users. Lovi trains its fit score models on a proprietary dataset built from more than 10,000 expert-labeled products and more than 100,000 simulated examples, following an internally consistent methodology presented at Cosmoprof, AMWC, and Skin of Color Update.
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Co-founder, Medical Director
Cosmetic chemist, cosmetologist, aesthetic products developer
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Co-founder, CEO and CTO
PhD in computer science, 3x US patent holder, ex-Google, ex-Yandex
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Dr. Sof铆a Perea P茅rez, MD, MSc
Medical Board
Aesthetic medicine practitioner, MSc in Longevity and Anti-Aging Medicine
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Medical Board
Specialist dermatologist, MBBS, MD, IFAAD
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Medical Board
Cosmetic chemist, SCS, IFSCC member
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Medical Board, Medical Advisor
Dermatology MD
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Elina Nazarenko, MD
Medical Board
Dermatology and diagnostic consultant
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Victoria Derkova, MS
Medical Board
Cosmetic chemist, cosmetic development technologist
How does it fit your skin?
Scan your face, then any product: Lovi shows how well it fits you and what fits even better.


