# Mesoestetic vs Endocare Page: https://lovi.care/skincare/ae/compare/mesoestetic-vs-endocare The Lovi Fit is the same in every country; only the stores and prices differ, and the ones here are for the United Arab Emirates. Mesoestetic and Endocare are respected Spanish skincare brands offering sophisticated formulas. The former is known for its targeted [serums](https://lovi.care/skincare/ae/ingredients/serum) featuring meticulous ingredients, while the latter is beloved for its nurturing moisturizers. Both brands suit mature skin best, though the first also serves sensitive and uneven skin types, and the second accommodates dry skin. They differ in their standout acne solutions, with Mesoestetic relying on the Cosmelan 2 and Endocare utilizing the Tensage Cream. Mesoestetic is a Spanish skincare brand founded in 1984 and owned by Mesoestetic Pharma Group, S.L.. [mesoestetic.com](https://www.mesoestetic.com/about-us) [tracxn.com](https://tracxn.com/d/companies/mesoestetic/__1eAnF7uALQzHII_So8HqZbHfSUJuilusj9hTisrG0tk) Endocare is a Spanish skincare brand founded in 1996 and owned by Cantabria Labs. [pitchbook.com](https://pitchbook.com/profiles/company/267212-62) [endocare.com.tw](https://www.endocare.com.tw/) This page compares some of the most popular Mesoestetic and Endocare products; for every product of both brands, with a fit score for your own skin, [use the Lovi app](https://app.pora.ai/vqqJ/j1xj2b6o?af_sub2=compare&af_sub3=selection_note&af_sub4=pga821250650). ### Popular Mesoestetic vs Endocare products #### Mesoestetic - [Cosmelan 2](https://lovi.care/skincare/ae/p/mesoestetic/cosmelan-2/for/acne-prone-skin) — Average fit #### Endocare - [Tensage Cream](https://lovi.care/skincare/ae/p/endocare/tensage-cream/for/mature-skin) — Average fit ## Questions and answers ### Mesoestetic or Endocare: which is better? Both Mesoestetic and Endocare offer fragrance-free formulas, but neither achieves a fit level higher than Average for the products on this page across any skin type. ### What is the difference between Mesoestetic and Endocare? Mesoestetic and Endocare both offer fragrance-free formulas, but they differ in their Lovi fit levels across skin types. Mesoestetic achieves an Average fit for acne-prone, oily, combination, and mature skin, while Endocare achieves an Average fit for mature, dry, and sensitive skin. ### Which is more affordable, Mesoestetic or Endocare? Neither Mesoestetic nor Endocare can be declared more affordable because the products on this page do not list any pricing information. ### Which causes fewer breakouts, Mesoestetic or Endocare? For acne-prone skin, Mesoestetic achieves an Average Lovi fit level with the products on this page, whereas Endocare reaches a Low fit level. Neither brand includes fragrance in its products on this page. ### When were Mesoestetic and Endocare founded and where are they from? Mesoestetic was founded in 1984 in Spain, while Endocare was founded in 1996 in Spain. ### Which brand makes Cosmelan 2 and which makes Tensage Cream? Mesoestetic makes Cosmelan 2, and Endocare makes Tensage Cream. ### Do any of the Mesoestetic or Endocare products on this page contain fragrance? None of the Mesoestetic and Endocare products on this page contain fragrance, as every product lists no fragrance in its ingredients. ## Research behind their key ingredients - [The effect of niacinamide on reducing cutaneous pigmentation and suppression of melanosome transfer](https://pubmed.ncbi.nlm.nih.gov/12100180/) Niacinamide · The British Journal of Dermatology, 2002 - [Treatment of acne with a combination of propolis, tea tree oil, and Aloe vera compared to erythromycin cream: two double-blind investigations](https://pubmed.ncbi.nlm.nih.gov/30588129/) Aloe barbadensis leaf juice · Clinical Pharmacology, 2018 - [Tailoring of Retinyl Palmitate-Based Ethosomal Hydrogel as a Novel Nanoplatform for Acne Vulgaris Management: Fabrication, Optimization, and Clinical Evaluation Employing a Split-Face Comparative Study](https://pubmed.ncbi.nlm.nih.gov/34211271/) Retinyl palmitate · International Journal of Nanomedicine, 2021 - [Efficacy and Safety of Azelaic Acid Nanocrystal-Loaded In Situ Hydrogel in the Treatment of Acne Vulgaris](https://pubmed.ncbi.nlm.nih.gov/33923739/) Azelaic acid · Pharmaceutics, 2021 - [The 24-hour skin hydration and barrier function effects of a hyaluronic 1%, glycerin 5%, and Centella asiatica stem cells extract moisturizing fluid: an intra-subject, randomized, assessor-blinded study](https://pubmed.ncbi.nlm.nih.gov/28860834/) Glycerin · Clinical, Cosmetic and Investigational Dermatology, 2017 - [A Double-Blinded, Randomized, Vehicle-Controlled Study of the Efficacy of Moisturizer Containing Licochalcone A, Decanediol, L-Carnitine, and Salicylic Acid for Prevention of Acne Relapse in Asian Population](https://pubmed.ncbi.nlm.nih.gov/33150170/) Salicylic acid · BioMed Research International, 2020 - [The Effects of Filtrate of the Secretion of the Cryptomphalus Aspersa on Photoaged Skin](https://pubmed.ncbi.nlm.nih.gov/23652894/) Sca · Journal of Drugs in Dermatology, 2013 - [Efficacy of a multitargeted, salicylic acid-based dermocosmetic cream compared to benzoyl peroxide 5% in Acne vulgaris: Results from a randomized study](https://pubmed.ncbi.nlm.nih.gov/37941097/) Salicylic acid · Journal of Cosmetic Dermatology, 2024 - [Effects of 15% Azelaic Acid Gel in the Management of Post-Inflammatory Erythema and Post-Inflammatory Hyperpigmentation in Acne Vulgaris](https://pubmed.ncbi.nlm.nih.gov/38734843/) Azelaic acid · Dermatology and Therapy, 2024 - [A Salicylic Acid-Based Dermocosmetic is Effective as an Adjunct to Benzoyl Peroxide for Mild to Moderate Acne and as Monotherapy in Maintenance Post Benzoyl Peroxide](https://pubmed.ncbi.nlm.nih.gov/38051857/) Salicylic acid · Journal of Drugs in Dermatology, 2023 - [The Moisturizing Efficacy of a Proprietary Dermo-Cosmetic Product( CLS02021) Versus Placebo in a 4-week Application Period](https://pubmed.ncbi.nlm.nih.gov/35774045/) Proprietary · Medical Archives, 2022 - [Efficacy and Safety of a New Cosmeceutical Regimen Based on the Combination of Snail Secretion Filtrate and Snail Egg Extract to Improve Signs of Skin Aging](https://pubmed.ncbi.nlm.nih.gov/32308795/) Sca · The Journal of Clinical and Aesthetic Dermatology, 2020 - [Effect of an Emollient Emulsion Containing 15.0% of Caprylic/Capric Triglyceride on the Urocanic Acid of the Stratum Corneum](https://pubmed.ncbi.nlm.nih.gov/37109405/) Caprylic capric triglyceride · Life, 2023 - [Efficacy and safety of a facial serum containing snail secretion filtrate, Calendula officinalis, and Glycyrrhiza glaba root extract in the treatment of maskne: A randomized placebo-controlled study](https://pubmed.ncbi.nlm.nih.gov/35763437/) Snail secretion filtrate sca growth factor technology filtrate · Journal of Cosmetic Dermatology, 2022 - [A novel facial moisturizer containing Saccharide isomerate accelerates skin barrier restoration following intense pulsed light treatment: a randomized split-face study](https://pubmed.ncbi.nlm.nih.gov/41211697/) Saccharide isomerate · The Journal of Dermatological Treatment, 2025 ## The brands - Spanish skincare: [Mesoestetic](https://lovi.care/skincare/ae/brands/mesoestetic) - Spanish skincare: [Endocare](https://lovi.care/skincare/ae/brands/endocare) ## More comparisons - [SKIN1004 vs Mesoestetic](https://lovi.care/skincare/ae/compare/skin1004-vs-mesoestetic) - [SKIN1004 vs Endocare](https://lovi.care/skincare/ae/compare/skin1004-vs-endocare) - [Anua vs Mesoestetic](https://lovi.care/skincare/ae/compare/anua-vs-mesoestetic) - [Anua vs Endocare](https://lovi.care/skincare/ae/compare/anua-vs-endocare) - [Medicube vs Mesoestetic](https://lovi.care/skincare/ae/compare/medicube-vs-mesoestetic) - [Medicube vs Endocare](https://lovi.care/skincare/ae/compare/medicube-vs-endocare) - [The Ordinary vs Mesoestetic](https://lovi.care/skincare/ae/compare/the-ordinary-vs-mesoestetic) - [The Ordinary vs Endocare](https://lovi.care/skincare/ae/compare/the-ordinary-vs-endocare) - [Beauty of Joseon vs Mesoestetic](https://lovi.care/skincare/ae/compare/beauty-of-joseon-vs-mesoestetic) - [Beauty of Joseon vs Endocare](https://lovi.care/skincare/ae/compare/beauty-of-joseon-vs-endocare) - [COSRX vs Mesoestetic](https://lovi.care/skincare/ae/compare/cosrx-vs-mesoestetic) - [COSRX vs Endocare](https://lovi.care/skincare/ae/compare/cosrx-vs-endocare) - [CeraVe vs Mesoestetic](https://lovi.care/skincare/ae/compare/cerave-vs-mesoestetic) - [CeraVe vs Endocare](https://lovi.care/skincare/ae/compare/cerave-vs-endocare) - [La Roche-Posay vs Mesoestetic](https://lovi.care/skincare/ae/compare/la-roche-posay-vs-mesoestetic) - [La Roche-Posay vs Endocare](https://lovi.care/skincare/ae/compare/la-roche-posay-vs-endocare) - [Dr. Althea vs Mesoestetic](https://lovi.care/skincare/ae/compare/dr-althea-vs-mesoestetic) - [Dr. Althea vs Endocare](https://lovi.care/skincare/ae/compare/dr-althea-vs-endocare) - [Some By Mi vs Mesoestetic](https://lovi.care/skincare/ae/compare/some-by-mi-vs-mesoestetic) - [Some By Mi vs Endocare](https://lovi.care/skincare/ae/compare/some-by-mi-vs-endocare) ## About the Lovi Fit Lovi: Unbiased, science-based skincare AI trained on real user outcomes. Lovi compares products by their fit scores, calculated from the full ingredient list with brand-independent rules its dermatologists and cosmetic chemists build and review, and personalizes every pick with AI trained on the real results of millions of users. Lovi trains its fit score models on a proprietary dataset built from more than 10,000 expert-labeled products and more than 100,000 simulated examples, following an internally consistent methodology presented at Cosmoprof, AMWC, and Skin of Color Update. Levels from best to worst: Superior, High, Average, Low, Caution, Warning. Behind this comparison: Nadia Kapleva, MS (Co-founder, Medical Director); Alexey Shagraev, PhD (Co-founder, CEO and CTO); Dr. Sofía Perea Pérez, MD, MSc (Medical Board); Aishani Shah, MD (Medical Board); Asya Zubkova, MS (Medical Board); Hanna Kurets, MD (Medical Board, Medical Advisor); Elina Nazarenko, MD (Medical Board); Victoria Derkova, MS (Medical Board). Page built Nov 8, 2026. More from Lovi: https://lovi.care/skincare/llms.txt ## This page in other countries - United States: https://lovi.care/skincare/compare/mesoestetic-vs-endocare - United Kingdom: https://lovi.care/skincare/uk/compare/mesoestetic-vs-endocare - Ireland: https://lovi.care/skincare/ie/compare/mesoestetic-vs-endocare - Germany: https://lovi.care/skincare/de/compare/mesoestetic-vs-endocare - France: https://lovi.care/skincare/fr/compare/mesoestetic-vs-endocare - Italy: https://lovi.care/skincare/it/compare/mesoestetic-vs-endocare - Netherlands: https://lovi.care/skincare/nl/compare/mesoestetic-vs-endocare - Spain: https://lovi.care/skincare/es/compare/mesoestetic-vs-endocare - Canada: https://lovi.care/skincare/ca/compare/mesoestetic-vs-endocare - Australia: https://lovi.care/skincare/au/compare/mesoestetic-vs-endocare - Singapore: https://lovi.care/skincare/sg/compare/mesoestetic-vs-endocare - Saudi Arabia: https://lovi.care/skincare/sa/compare/mesoestetic-vs-endocare - United Arab Emirates: https://lovi.care/skincare/ae/compare/mesoestetic-vs-endocare (this page)