# Menarini vs Sesderma Page: https://lovi.care/skincare/ae/compare/menarini-vs-sesderma The Lovi Fit is the same in every country; only the stores and prices differ, and the ones here are for the United Arab Emirates. Menarini and Sesderma are trusted skincare names known for their advanced [serums](https://lovi.care/skincare/ae/ingredients/serum) and meticulously engineered formulas that deliver reliable care. The first brand suits sensitive, dry, and combination skin best with gentle compositions, featuring the A-Ret Gel as its standout solution for acne-prone skin. Founded in 1989 and owned by Grupo Sesderma since 2026, the Spanish brand suits sensitive, hyperpigmented, and aging skin types best through botanical [extracts](https://lovi.care/skincare/ae/ingredients/extract) and active compounds that promote a radiant complexion, including the Azelac RU Serum for acne. While both offer thoughtful offerings to support a balanced complexion, they differ in their specific botanical focuses and targeted skin concerns. Sesderma is a Spanish skincare brand founded in 1989 and owned by Grupo Sesderma since 2026. [skinexpert.sesderma.com](https://skinexpert.sesderma.com/en/jb-capital-joins-the-shareholding-of-sesderma-group-as-a-strategic-partner/) [sesderma.com](https://www.sesderma.com/us_en/about-us.html) This page compares some of the most popular Menarini and Sesderma products; for every product of both brands, with a fit score for your own skin, [use the Lovi app](https://app.pora.ai/vqqJ/j1xj2b6o?af_sub2=compare&af_sub3=selection_note&af_sub4=pge9181925c6). ### Popular Menarini vs Sesderma products #### Sesderma - [Azelac RU Serum](https://lovi.care/skincare/ae/p/sesderma/azelac-ru-serum/for/acne-prone-skin) — High fit — [AED 123.63 at Amazon](https://www.amazon.ae/dp/B00987RKWW?tag=lovi00-21&linkCode=osi&th=1&psc=1) #### Menarini - [A-Ret Gel](https://lovi.care/skincare/ae/p/menarini/a-ret-gel/for/oily-skin) — High fit ### Menarini vs Sesderma [serums](https://lovi.care/skincare/ae/ingredients/serum) and treatments #### Sesderma - [Azelac RU Serum](https://lovi.care/skincare/ae/p/sesderma/azelac-ru-serum/for/acne-prone-skin) — High fit — [AED 123.63 at Amazon](https://www.amazon.ae/dp/B00987RKWW?tag=lovi00-21&linkCode=osi&th=1&psc=1) #### Menarini - [A-Ret Gel](https://lovi.care/skincare/ae/p/menarini/a-ret-gel/for/oily-skin) — High fit ## Questions and answers ### Menarini or Sesderma: which is better? For oily and acne-prone skin, Menarini has High Lovi fit products on this page, while Sesderma performs best for skin with dark spots, combination skin, and acne-prone skin with High Lovi fit levels. Menarini offers fragrance-free options across the products on this page, whereas Sesderma's Azelac RU [Serum](https://lovi.care/skincare/ae/ingredients/serum) includes fragrance. ### What is the difference between Menarini and Sesderma? Menarini features fragrance-free formulas with a High Lovi fit for oily and acne-prone skin, whereas Sesderma includes fragrance in its Azelac RU Serum which achieves a High fit for acne-prone skin, skin with dark spots, and combination skin. ### Which is more affordable, Menarini or Sesderma? Neither brand is more affordable because the page products for Menarini and Sesderma do not list prices. ### Which causes fewer breakouts, Menarini or Sesderma? For acne-prone skin, Menarini has a High fit for the products on this page, while Sesderma has an Average fit. Both brands feature formulations that help manage breakouts. [Clinical, Cosmetic and Investigational Dermatology, 2020](https://pubmed.ncbi.nlm.nih.gov/32210603/) [Pharmaceutics, 2021](https://pubmed.ncbi.nlm.nih.gov/33923739/) ### How do the founding years of Menarini and Sesderma compare? Menarini was founded earlier in 1886, while Sesderma was founded in 1989 in Spain. ### Which brand has products formulated without fragrance between Menarini and Sesderma? Menarini has products on this page formulated without fragrance, whereas Sesderma includes fragrance in its product. ### Where are Menarini and Sesderma headquartered or founded? Menarini was founded in 1886 with its founding location not specified, while Sesderma was founded in Spain in 1989. ## Research behind their key ingredients - [Vitamin A antagonizes decreased cell growth and elevated collagen-degrading matrix metalloproteinases and stimulates collagen accumulation in naturally aged human skin](https://pubmed.ncbi.nlm.nih.gov/10692106/) Retinol · The Journal of Investigative Dermatology, 2000 - [The effect of niacinamide on reducing cutaneous pigmentation and suppression of melanosome transfer](https://pubmed.ncbi.nlm.nih.gov/12100180/) Niacinamide · The British Journal of Dermatology, 2002 - [Restoration of collagen formation in photodamaged human skin by tretinoin (retinoic acid)](https://pubmed.ncbi.nlm.nih.gov/8336752/) Tretinoin · The New England Journal of Medicine, 1993 - [Improvement of naturally aged skin with vitamin A (retinol)](https://pubmed.ncbi.nlm.nih.gov/17515510/) Retinol · Archives of Dermatology, 2007 - [Nicotinic acid/niacinamide and the skin](https://pubmed.ncbi.nlm.nih.gov/17147561/) Niacin · Journal of Cosmetic Dermatology, 2004 - [Molecular basis of retinol anti-ageing properties in naturally aged human skin in vivo](https://pubmed.ncbi.nlm.nih.gov/27261203/) Retinol · International Journal of Cosmetic Science, 2017 - [Prospective, randomized, double-blind assessment of topical bakuchiol and retinol for facial photoageing](https://pubmed.ncbi.nlm.nih.gov/29947134/) Retinol · The British Journal of Dermatology, 2019 - [Clinical Assessment of New Topical Cream Containing Two Essential Oils Combined with Tretinoin in the Treatment of Acne](https://pubmed.ncbi.nlm.nih.gov/32210603/) Tretinoin · Clinical, Cosmetic and Investigational Dermatology, 2020 - [Efficacy and Safety of Azelaic Acid Nanocrystal-Loaded In Situ Hydrogel in the Treatment of Acne Vulgaris](https://pubmed.ncbi.nlm.nih.gov/33923739/) Azelaic acid · Pharmaceutics, 2021 - [A topical lipophilic niacin derivative increases NAD, epidermal differentiation and barrier function in photodamaged skin](https://pubmed.ncbi.nlm.nih.gov/17518989/) Niacin · Experimental Dermatology, 2007 - [Efficacy assessments of tretinoin-loaded nano lipid carriers in acne vulgaris: a double blind, split-face randomized clinical study](https://pubmed.ncbi.nlm.nih.gov/34146120/) Tretinoin · Archives of Dermatological Research, 2022 - [Topical tretinoin for treating photoaging: A systematic review of randomized controlled trials](https://pubmed.ncbi.nlm.nih.gov/35620028/) Tretinoin · International Journal of Women's Dermatology, 2022 - [Effects of 15% Azelaic Acid Gel in the Management of Post-Inflammatory Erythema and Post-Inflammatory Hyperpigmentation in Acne Vulgaris](https://pubmed.ncbi.nlm.nih.gov/38734843/) Azelaic acid · Dermatology and Therapy, 2024 - [Influence of vitamin E acetate on stratum corneum hydration](https://pubmed.ncbi.nlm.nih.gov/9706379/) Tocopheryl acetate · Arzneimittel-Forschung, 1998 - [Nanostructured Lipid Carrier Based Gel Containing α-Tocopherol and α-Tocopheryl Acetate for Synergistic Cutaneous Antiaging Efficacy](https://pubmed.ncbi.nlm.nih.gov/41309687/) Tocopheryl acetate · Scientific Reports, 2025 - [Safety assessment on comedogenicity of dermatological products containing d-alpha tocopheryl acetate in Asian subjects: A double-blind randomized controlled trial](https://pubmed.ncbi.nlm.nih.gov/34471722/) Tocopheryl acetate · Contemporary Clinical Trials Communications, 2021 - [The efficacy of enoxolone in reducing erythema and pain after laser treatment: A randomized split-face pilot study](https://pubmed.ncbi.nlm.nih.gov/38622995/) Glycyrrhetinic acid · Journal of Cosmetic Dermatology, 2024 ## The brands - Skincare: [Menarini](https://lovi.care/skincare/ae/brands/menarini) - Spanish skincare: [Sesderma](https://lovi.care/skincare/ae/brands/sesderma) ## More comparisons - [SKIN1004 vs Menarini](https://lovi.care/skincare/ae/compare/skin1004-vs-menarini) - [SKIN1004 vs Sesderma](https://lovi.care/skincare/ae/compare/skin1004-vs-sesderma) - [Anua vs Menarini](https://lovi.care/skincare/ae/compare/anua-vs-menarini) - [Anua vs Sesderma](https://lovi.care/skincare/ae/compare/anua-vs-sesderma) - [Medicube vs Menarini](https://lovi.care/skincare/ae/compare/medicube-vs-menarini) - [Medicube vs Sesderma](https://lovi.care/skincare/ae/compare/medicube-vs-sesderma) - [The Ordinary vs Menarini](https://lovi.care/skincare/ae/compare/the-ordinary-vs-menarini) - [The Ordinary vs Sesderma](https://lovi.care/skincare/ae/compare/the-ordinary-vs-sesderma) - [Beauty of Joseon vs Menarini](https://lovi.care/skincare/ae/compare/beauty-of-joseon-vs-menarini) - [Beauty of Joseon vs Sesderma](https://lovi.care/skincare/ae/compare/beauty-of-joseon-vs-sesderma) - [COSRX vs Menarini](https://lovi.care/skincare/ae/compare/cosrx-vs-menarini) - [COSRX vs Sesderma](https://lovi.care/skincare/ae/compare/cosrx-vs-sesderma) - [CeraVe vs Menarini](https://lovi.care/skincare/ae/compare/cerave-vs-menarini) - [CeraVe vs Sesderma](https://lovi.care/skincare/ae/compare/cerave-vs-sesderma) - [La Roche-Posay vs Menarini](https://lovi.care/skincare/ae/compare/la-roche-posay-vs-menarini) - [La Roche-Posay vs Sesderma](https://lovi.care/skincare/ae/compare/la-roche-posay-vs-sesderma) - [Dr. Althea vs Menarini](https://lovi.care/skincare/ae/compare/dr-althea-vs-menarini) - [Dr. Althea vs Sesderma](https://lovi.care/skincare/ae/compare/dr-althea-vs-sesderma) - [Some By Mi vs Menarini](https://lovi.care/skincare/ae/compare/some-by-mi-vs-menarini) - [Some By Mi vs Sesderma](https://lovi.care/skincare/ae/compare/some-by-mi-vs-sesderma) ## About the Lovi Fit Lovi: Unbiased, science-based skincare AI trained on real user outcomes. Lovi compares products by their fit scores, calculated from the full ingredient list with brand-independent rules its dermatologists and cosmetic chemists build and review, and personalizes every pick with AI trained on the real results of millions of users. Lovi trains its fit score models on a proprietary dataset built from more than 10,000 expert-labeled products and more than 100,000 simulated examples, following an internally consistent methodology presented at Cosmoprof, AMWC, and Skin of Color Update. Levels from best to worst: Superior, High, Average, Low, Caution, Warning. Behind this comparison: Nadia Kapleva, MS (Co-founder, Medical Director); Alexey Shagraev, PhD (Co-founder, CEO and CTO); Dr. Sofía Perea Pérez, MD, MSc (Medical Board); Aishani Shah, MD (Medical Board); Asya Zubkova, MS (Medical Board); Hanna Kurets, MD (Medical Board, Medical Advisor); Elina Nazarenko, MD (Medical Board); Victoria Derkova, MS (Medical Board). Page built Nov 8, 2026. More from Lovi: https://lovi.care/skincare/llms.txt ## This page in other countries - United States: https://lovi.care/skincare/compare/menarini-vs-sesderma - United Kingdom: https://lovi.care/skincare/uk/compare/menarini-vs-sesderma - Ireland: https://lovi.care/skincare/ie/compare/menarini-vs-sesderma - Germany: https://lovi.care/skincare/de/compare/menarini-vs-sesderma - France: https://lovi.care/skincare/fr/compare/menarini-vs-sesderma - Italy: https://lovi.care/skincare/it/compare/menarini-vs-sesderma - Netherlands: https://lovi.care/skincare/nl/compare/menarini-vs-sesderma - Spain: https://lovi.care/skincare/es/compare/menarini-vs-sesderma - Canada: https://lovi.care/skincare/ca/compare/menarini-vs-sesderma - Australia: https://lovi.care/skincare/au/compare/menarini-vs-sesderma - Singapore: https://lovi.care/skincare/sg/compare/menarini-vs-sesderma - Saudi Arabia: https://lovi.care/skincare/sa/compare/menarini-vs-sesderma - United Arab Emirates: https://lovi.care/skincare/ae/compare/menarini-vs-sesderma (this page)