# Medicube vs Luna Nectar

Page: https://lovi.care/skincare/ae/compare/medicube-vs-luna-nectar

The Lovi Fit is the same in every country; only the stores and prices differ, and the ones here are for the United Arab Emirates.

Medicube and Luna Nectar are distinct skincare brands founded in 2016 and 2017 respectively. The Korean brand is known for moisturizers, [serums](https://lovi.care/skincare/ae/ingredients/serum), toners, and masks featuring [niacinamide](https://lovi.care/skincare/ae/ingredients/niacinamide), [collagen](https://lovi.care/skincare/ae/ingredients/collagen), and [hyaluronic acid](https://lovi.care/skincare/ae/ingredients/hyaluronic-acid), suiting oily acne-prone and oily skin best. Conversely, the Canadian brand is cherished for nutrient-rich serums and meticulously blended formulas that suit sensitive, dry, and mature skin best. Ultimately, both offer tailored solutions while differing in their regional origins, key ingredients, and targeted skin types.

Medicube is a Korean skincare brand founded in 2016 and owned by APR Corp..

[medicubereviews.co.uk](https://medicubereviews.co.uk/medicube/story/) [glossy.co](https://www.glossy.co/beauty/medicubes-founder-on-the-products-and-people-that-fueled-the-k-beauty-brands-booming-year/)

Luna Nectar is a Canadian skincare brand founded in 2017 and owned by Luna Nectar Organics Inc..

[tracxn.com](https://tracxn.com/d/companies/luna-nectar/__3__YNyI5LQGYMgx_K1fMebUciccyZimzjzMKzRFnYS8) [pitchbook.com](https://pitchbook.com/profiles/company/512494-03)

This page compares some of the most popular Medicube and Luna Nectar products; for every product of both brands, with a fit score for your own skin, [use the Lovi app](https://app.pora.ai/vqqJ/j1xj2b6o?af_sub2=compare&af_sub3=selection_note&af_sub4=pgc05174afb2).

### Popular Medicube vs Luna Nectar products

#### Medicube

- [Zero Pore Pad](https://lovi.care/skincare/ae/p/medicube/zero-pore-pad/for/oily-skin) — Superior fit — [AED 41.99 at Amazon](https://www.amazon.ae/dp/B0CW1KV8B6?tag=lovi00-21&linkCode=osi&th=1&psc=1)
- [PDRN Pink Peptide Serum](https://lovi.care/skincare/ae/p/medicube/pdrn-pink-peptide-serum/for/mature-skin) — High fit — [AED 35.00 at Amazon](https://www.amazon.ae/dp/B0DBF65JYY?tag=lovi00-21&linkCode=osi&th=1&psc=1)
- [Collagen Jelly Cream](https://lovi.care/skincare/ae/p/medicube/collagen-jelly-cream/for/mature-skin) — Superior fit — [AED 37.99 at Amazon](https://www.amazon.ae/dp/B0CM2PPNMW?tag=lovi00-21&linkCode=osi&th=1&psc=1)
- [Collagen Night Wrapping Mask](https://lovi.care/skincare/ae/p/medicube/collagen-night-wrapping-mask/for/dry-skin) — High fit — [AED 35.00 at Amazon](https://www.amazon.ae/dp/B0BRMYHMS5?tag=lovi00-21&linkCode=osi&th=1&psc=1)
- [PDRN Pink Collagen Gel Mask](https://lovi.care/skincare/ae/p/medicube/pdrn-pink-collagen-gel-mask/for/dry-sensitive-skin) — High fit — [AED 35.00 at Amazon](https://www.amazon.ae/dp/B0DGTMR754?tag=lovi00-21&linkCode=osi&th=1&psc=1)
- [DEEP VITA-C CAPSULE CREAM](https://lovi.care/skincare/ae/p/medicube/deep-vita-c-capsule-cream/for/sensitive-skin) — Average fit — [AED 44.79 at Amazon](https://www.amazon.ae/dp/B0D2Z3GGCY?tag=lovi00-21&linkCode=osi&th=1&psc=1)
- [TRIPLE COLLAGEN CREAM](https://lovi.care/skincare/ae/p/medicube/triple-collagen-cream/for/mature-skin) — Average fit — [AED 45.99 at Amazon](https://www.amazon.ae/dp/B0BPXT3GBN?tag=lovi00-21&linkCode=osi&th=1&psc=1)
- [Zero Foam Cleanser](https://lovi.care/skincare/ae/p/medicube/zero-foam-cleanser/for/dry-skin) — Superior fit — [AED 38.99 at Amazon](https://www.amazon.ae/dp/B09C1B7BH5?tag=lovi00-21&linkCode=osi&th=1&psc=1)

#### Luna Nectar

- [Futurize](https://lovi.care/skincare/ae/p/luna-nectar/futurize/for/dry-sensitive-skin) — High fit

### Medicube vs Luna Nectar [serums](https://lovi.care/skincare/ae/ingredients/serum) and treatments

#### Medicube

- [Red Succinic Acid Peeling Pad](https://lovi.care/skincare/ae/p/medicube/red-succinic-acid-peeling-pad/for/oily-acne-prone-skin) — Superior fit — [AED 43.99 at Amazon](https://www.amazon.ae/dp/B0CV7RX6ML?tag=lovi00-21&linkCode=osi&th=1&psc=1)
- [Deep Vita C Pad](https://lovi.care/skincare/ae/p/medicube/deep-vita-c-pad/for/oily-acne-prone-skin) — High fit — [AED 34.50 at Amazon](https://www.amazon.ae/dp/B0BPLYHDPG?tag=lovi00-21&linkCode=osi&th=1&psc=1)
- [One Day Exosome Shot 2000](https://lovi.care/skincare/ae/p/medicube/one-day-exosome-shot-2000/for/acne-prone-skin) — High fit — [AED 35.00 at Amazon](https://www.amazon.ae/dp/B0D16L5F2M?tag=lovi00-21&linkCode=osi&th=1&psc=1)
- [Zero Pore One Day Serum](https://lovi.care/skincare/ae/p/medicube/zero-pore-one-day-serum/for/dark-spots) — High fit — [AED 55.00 at Amazon](https://www.amazon.ae/dp/B09G267W27?tag=lovi00-21&linkCode=osi&th=1&psc=1)
- [Zero Exosome Shot](https://lovi.care/skincare/ae/p/medicube/zero-exosome-shot/for/oily-skin) — High fit — [AED 36.99 at Amazon](https://www.amazon.ae/dp/B0D137TMRB?tag=lovi00-21&linkCode=osi&th=1&psc=1)
- [Deep Vita A Retinol Serum](https://lovi.care/skincare/ae/p/medicube/deep-vita-a-retinol-serum/for/acne-prone-skin) — Average fit

#### Luna Nectar

- [Futurize](https://lovi.care/skincare/ae/p/luna-nectar/futurize/for/dry-sensitive-skin) — High fit

## Questions and answers

### Medicube or Luna Nectar: which is better?

Medicube offers a much wider range of products that are a superior or high Lovi fit for oily and acne-prone skin, while Luna Nectar features a single targeted [serum](https://lovi.care/skincare/ae/ingredients/serum). Medicube is often noted for deep hydration and smoother texture, though some reviewers mention sticky residue.

### What is the difference between Medicube and Luna Nectar?

Medicube offers a large variety of products that fit oily and acne-prone skin best, while Luna Nectar features a focused serum that works well for dry and sensitive skin. Medicube products on this page often help provide deep hydration and a radiant glow, though some may cause sticky residue or breakouts.

### Which is more affordable, Medicube or Luna Nectar?

Neither the page facts nor the studies provide pricing information to determine whether Medicube or Luna Nectar is more affordable.

### Which causes fewer breakouts, Medicube or Luna Nectar?

Luna Nectar is unlikely to cause breakouts as it features fragrance-free formulas, whereas Medicube has products like its Red Foam Cleanser and Zero Pore Blackhead Mud Mask that may occasionally lead to irritation and breakouts according to reviewer feedback.

### How do the founding years and countries of origin compare between Medicube and Luna Nectar?

Medicube was founded in 2016 in South Korea, while Luna Nectar was founded in 2017 in Canada.

### Which products from Medicube contain fragrance compared to Luna Nectar's completely fragrance-free lineup?

Medicube offers two products on this page containing fragrance, which are the [Collagen](https://lovi.care/skincare/ae/ingredients/collagen) Jelly Cream and the Deep Vita A [Retinol](https://lovi.care/skincare/ae/ingredients/retinol) Serum, while Luna Nectar maintains a completely fragrance-free lineup.

### What are the most commonly mentioned positive and negative review points for Medicube skincare products?

Reviewers of Medicube products most commonly mention deep hydration moisturizers, radiant glow, and smoother skin texture as positive points. On the downside, shoppers frequently point out a sticky residue, small quantities, and pricing issues.

## Research behind their key ingredients

- [Vitamin A antagonizes decreased cell growth and elevated collagen-degrading matrix metalloproteinases and stimulates collagen accumulation in naturally aged human skin](https://pubmed.ncbi.nlm.nih.gov/10692106/) Retinol · The Journal of Investigative Dermatology, 2000
- [The effect of niacinamide on reducing cutaneous pigmentation and suppression of melanosome transfer](https://pubmed.ncbi.nlm.nih.gov/12100180/) Niacinamide · The British Journal of Dermatology, 2002
- [Mechanistic Basis and Clinical Evidence for the Applications of Nicotinamide (Niacinamide) to Control Skin Aging and Pigmentation](https://pubmed.ncbi.nlm.nih.gov/34439563/) Niacinamide · Antioxidants, 2021
- [Benefits of topical hyaluronic acid for skin quality and signs of skin aging: From literature review to clinical evidence](https://pubmed.ncbi.nlm.nih.gov/36200921/) Hyaluronic acid, Sodium hyaluronate · Dermatologic Therapy, 2022
- [Topical use of dexpanthenol in skin disorders](https://pubmed.ncbi.nlm.nih.gov/12113650/) Panthenol · American Journal of Clinical Dermatology, 2002
- [The Effect of Aloe Vera Clinical Trials on Prevention and Healing of Skin Wound: A Systematic Review](https://pubmed.ncbi.nlm.nih.gov/30666070/) Aloe barbadensis extract · Iranian Journal of Medical Sciences, 2019
- [Efficacy of combined treatment with human adipose tissue stem cell-derived exosome-containing solution and microneedling for facial skin aging: A 12-week prospective, randomized, split-face study](https://pubmed.ncbi.nlm.nih.gov/37377400/) Exosome cica · Journal of Cosmetic Dermatology, 2023
- [Improvement of naturally aged skin with vitamin A (retinol)](https://pubmed.ncbi.nlm.nih.gov/17515510/) Retinol · Archives of Dermatology, 2007
- [Topical ascorbic acid on photoaged skin. Clinical, topographical and ultrastructural evaluation: double-blind study vs. placebo](https://pubmed.ncbi.nlm.nih.gov/12823436/) Vitamin c derivatives · Experimental Dermatology, 2003
- [Topical application of glycolic acid suppresses the UVB induced IL-6, IL-8, MCP-1 and COX-2 inflammation by modulating NF-κB signaling pathway in keratinocytes and mice skin](https://pubmed.ncbi.nlm.nih.gov/28330776/) Aha · Journal of Dermatological Science, 2017
- [Collagen Supplements for Aging and Wrinkles: A Paradigm Shift in the Fields of Dermatology and Cosmetics](https://pubmed.ncbi.nlm.nih.gov/35223163/) Collagen, Water-soluble collagen · Dermatology Practical & Conceptual, 2022
- [Topical palmitoyl pentapeptide provides improvement in photoaged human facial skin](https://pubmed.ncbi.nlm.nih.gov/18492182/) Palmitoyl pentapeptide-4 · International Journal of Cosmetic Science, 2005
- [Tea tree oil reduces histamine-induced skin inflammation](https://pubmed.ncbi.nlm.nih.gov/12452873/) Tree · The British Journal of Dermatology, 2002
- [Prospective, randomized, double-blind assessment of topical bakuchiol and retinol for facial photoageing](https://pubmed.ncbi.nlm.nih.gov/29947134/) Bakuchiol · The British Journal of Dermatology, 2019
- [Apigenin inhibits UVA-induced cytotoxicity in vitro and prevents signs of skin aging in vivo](https://pubmed.ncbi.nlm.nih.gov/27279007/) Chamomile extract · International Journal of Molecular Medicine, 2016
- [Moisturizing and Antiinflammatory Properties of Cosmetic Formulations Containing Centella asiatica Extract](https://pubmed.ncbi.nlm.nih.gov/27168678/) Centella asiatica extract, Madecassoside · Indian Journal of Pharmaceutical Sciences, 2016
- [Use of Collagen in Cosmetic Products](https://pubmed.ncbi.nlm.nih.gov/38534748/) Collagen, Water-soluble collagen · Current Issues in Molecular Biology, 2024
- [Treatment of acne with a combination of propolis, tea tree oil, and Aloe vera compared to erythromycin cream: two double-blind investigations](https://pubmed.ncbi.nlm.nih.gov/30588129/) Aloe barbadensis extract · Clinical Pharmacology, 2018
- [Effect of Camellia japonica oil on human type I procollagen production and skin barrier function](https://pubmed.ncbi.nlm.nih.gov/17386986/) Camellia japonica flower extract · Journal of Ethnopharmacology, 2007
- [Ceramide 1 and ceramide 3 act synergistically on skin hydration and the transepidermal water loss of sodium lauryl sulfate-irritated skin](https://pubmed.ncbi.nlm.nih.gov/18717861/) Ceramide np · International Journal of Dermatology, 2008
- [Green tea extract reduces induction of p53 and apoptosis in UVB-irradiated human skin independent of transcriptional controls](https://pubmed.ncbi.nlm.nih.gov/18631247/) Camellia sinensis leaf extract · Experimental Dermatology, 2009
- [Clinical, biometric and structural evaluation of the long-term effects of a topical treatment with ascorbic acid and madecassoside in photoaged human skin](https://pubmed.ncbi.nlm.nih.gov/18503551/) Centella asiatica leaf extract · Experimental Dermatology, 2008
- [The 24-hour skin hydration and barrier function effects of a hyaluronic 1%, glycerin 5%, and Centella asiatica stem cells extract moisturizing fluid: an intra-subject, randomized, assessor-blinded study](https://pubmed.ncbi.nlm.nih.gov/28860834/) Glycerin · Clinical, Cosmetic and Investigational Dermatology, 2017
- [Randomized controlled study for the anti-aging effect of human adipocyte-derived mesenchymal stem cell media combined with niacinamide after laser therapy](https://pubmed.ncbi.nlm.nih.gov/33103316/) Niacinamide · Journal of Cosmetic Dermatology, 2021
- [The Effects of a Standardized Extract of Centella asiatica on Postlaser Resurfacing Wound Healing on the Face: A Split-Face, Double-Blind, Randomized, Placebo-Controlled Trial](https://pubmed.ncbi.nlm.nih.gov/32310680/) Madecassoside · Journal of Alternative and Complementary Medicine, 2020
- [The anti-wrinkle efficacy of argireline, a synthetic hexapeptide, in Chinese subjects: a randomized, placebo-controlled study](https://pubmed.ncbi.nlm.nih.gov/23417317/) Acetyl hexapeptide-8 · American Journal of Clinical Dermatology, 2013
- [Protective effects of Camellia japonica flower extract against urban air pollutants](https://pubmed.ncbi.nlm.nih.gov/30691451/) Camellia japonica flower extract · BMC Complementary and Alternative Medicine, 2019
- [Quaternized carboxymethyl chitosan/organic montmorillonite nanocomposite as a novel cosmetic ingredient against skin aging](https://pubmed.ncbi.nlm.nih.gov/28732847/) Bentonite · Carbohydrate Polymers, 2017
- [A Double-Blinded, Randomized, Vehicle-Controlled Study of the Efficacy of Moisturizer Containing Licochalcone A, Decanediol, L-Carnitine, and Salicylic Acid for Prevention of Acne Relapse in Asian Population](https://pubmed.ncbi.nlm.nih.gov/33150170/) Salicylic acid · BioMed Research International, 2020
- [Senomorphic activity of a combination of niacinamide and hyaluronic acid: correlation with clinical improvement of skin aging](https://pubmed.ncbi.nlm.nih.gov/39009698/) Niacinamide · Scientific Reports, 2024
- [A new topical panthenol-containing emollient: Results from two randomized controlled studies assessing its skin moisturization and barrier restoration potential, and the effect on skin microflora](https://pubmed.ncbi.nlm.nih.gov/27425824/) Panthenol · The Journal of Dermatological Treatment, 2017
- [Development and photoprotective effect of a sunscreen containing the antioxidants Spirulina and dimethylmethoxy chromanol on sun-induced skin damage](https://pubmed.ncbi.nlm.nih.gov/28341613/) Dimethylmethoxy chromanol · European Journal of Pharmaceutical Sciences, 2017
- [Microneedling by dermapen and glycolic acid peel for the treatment of acne scars: Comparative study](https://pubmed.ncbi.nlm.nih.gov/30548170/) Glycolic acid · Journal of Cosmetic Dermatology, 2019
- [Adenosine-loaded dissolving microneedle patches to improve skin wrinkles, dermal density, elasticity and hydration](https://pubmed.ncbi.nlm.nih.gov/29574973/) Adenosine · International Journal of Cosmetic Science, 2018
- [Hydrolyzed Collagen Induces an Anti-Inflammatory Response That Induces Proliferation of Skin Fibroblast and Keratinocytes](https://pubmed.ncbi.nlm.nih.gov/36501011/) Collagen extract · Nutrients, 2022
- [Efficacy of a topical gel containing chitosan, chlorhexidine, allantoin and dexpanthenol for pain and inflammation control after third molar surgery: A randomized and placebo-controlled clinical trial](https://pubmed.ncbi.nlm.nih.gov/32683390/) Allantoin · Medicina Oral, Patologia Oral Y Cirugia Bucal, 2020
- [Sunscreens and Cosmetic Formulations Containing Ascorbyl Tetraisopalmitate and Rice Peptides for the Improvement of Skin Photoaging: A Double-blind, Randomized Placebo-controlled Clinical Study](https://pubmed.ncbi.nlm.nih.gov/33529350/) Vitamin c derivatives · Photochemistry and Photobiology, 2021
- [The efficacy of glycolic acid, salicylic acid, gluconolactone, and licochalcone A combined with 0.1% adapalene vs adapalene monotherapy in mild-to-moderate acne vulgaris: a double-blinded within-person comparative study](https://pubmed.ncbi.nlm.nih.gov/30858720/) Glycolic acid, Gluconolactone · Clinical, Cosmetic and Investigational Dermatology, 2019
- [Systematic Study of Paeonol/Madecassoside Co-Delivery Nanoemulsion Transdermal Delivery System for Enhancing Barrier Repair and Anti-Inflammatory Efficacy](https://pubmed.ncbi.nlm.nih.gov/37446936/) Centella asiatica extract, Madecassoside, Centella asiatica leaf extract · Molecules, 2023
- [A comparative study of gluconolactone versus benzoyl peroxide in the treatment of acne](https://pubmed.ncbi.nlm.nih.gov/1303072/) Gluconolactone · The Australasian Journal of Dermatology, 1992
- [Anti-Wrinkle Efficacy of Cross-Linked Hyaluronic Acid-Based Microneedle Patch with Acetyl Hexapeptide-8 and Epidermal Growth Factor on Korean Skin](https://pubmed.ncbi.nlm.nih.gov/33911590/) Acetyl hexapeptide-8 · Annals of Dermatology, 2019
- [Efficacy of a multitargeted, salicylic acid-based dermocosmetic cream compared to benzoyl peroxide 5% in Acne vulgaris: Results from a randomized study](https://pubmed.ncbi.nlm.nih.gov/37941097/) Salicylic acid · Journal of Cosmetic Dermatology, 2024
- [A Lipid Mixture Enriched by Ceramide NP with Fatty Acids of Diverse Chain Lengths Contributes to Restore the Skin Barrier Function Impaired by Topical Corticosteroid](https://pubmed.ncbi.nlm.nih.gov/34348350/) Ceramide np · Skin Pharmacology and Physiology, 2022
- [Acid-base combination principles for preparation of anti-acne dissolving microneedles loaded with azelaic acid and matrine](https://pubmed.ncbi.nlm.nih.gov/34284096/) Sophora angustifolia root extract, Sophora flavescens root extract · European Journal of Pharmaceutical Sciences, 2021
- [Clay jojoba oil facial mask for lesioned skin and mild acne--results of a prospective, observational pilot study](https://pubmed.ncbi.nlm.nih.gov/22585103/) Jojoba oil · Forschende Komplementarmedizin, 2012
- [A Salicylic Acid-Based Dermocosmetic is Effective as an Adjunct to Benzoyl Peroxide for Mild to Moderate Acne and as Monotherapy in Maintenance Post Benzoyl Peroxide](https://pubmed.ncbi.nlm.nih.gov/38051857/) Salicylic acid · Journal of Drugs in Dermatology, 2023
- [Comparison of skin calming effects of cosmetic products containing 4-t-butylcyclohexanol or acetyl dipeptide-1 cetyl ester on capsaicin-induced facial stinging in volunteers with sensitive skin](https://pubmed.ncbi.nlm.nih.gov/26805418/) Lifting peptide · Journal of the European Academy of Dermatology and Venereology, 2016
- [Efficacy and safety of moisturizer containing 5% panthenol, madecassoside, and copper-zinc-manganese versus 0.02% triamcinolone acetonide cream in decreasing adverse reaction and downtime after ablative fractional carbon dioxide laser resurfacing: A split-face, double-blinded, randomized, controlled trial](https://pubmed.ncbi.nlm.nih.gov/30945430/) Centella asiatica leaf extract · Journal of Cosmetic Dermatology, 2019
- [A dermocosmetic containing bakuchiol, Ginkgo biloba extract and mannitol improves the efficacy of adapalene in patients with acne vulgaris: result from a controlled randomized trial](https://pubmed.ncbi.nlm.nih.gov/25914553/) Bakuchiol · Clinical, Cosmetic and Investigational Dermatology, 2015
- [Stretchable skin hydrating PVB patches with controlled pores' size and shape for deliberate evening primrose oil spreading, transport and release](https://pubmed.ncbi.nlm.nih.gov/35929319/) Oenothera biennis flower extract · Biomaterials Advances, 2022
- [Effects of 1,3-propanediol associated, or not, with butylene glycol and/or glycerol on skin hydration and skin barrier function](https://pubmed.ncbi.nlm.nih.gov/37699769/) Propanediol · International Journal of Cosmetic Science, 2024
- [Antiacne and antiblotch activities of a formulated combination of Aloe barbadensis leaf powder, Garcinia mangostana peel extract, and Camellia sinensis leaf extract](https://pubmed.ncbi.nlm.nih.gov/31239743/) Camellia sinensis leaf extract · Clinical, Cosmetic and Investigational Dermatology, 2019
- [New clinical approach in facial mild-moderate acne: Re-stabilization of skin microbiota balance with a topical biotechnological phytocomplex](https://pubmed.ncbi.nlm.nih.gov/39205505/) Succinic acid · Journal of Cosmetic Dermatology, 2024
- [The efficacy study of the combination of tripeptide-10-citrulline and acetyl hexapeptide-3. A prospective, randomized controlled study](https://pubmed.ncbi.nlm.nih.gov/28150423/) Acetyl hexapeptide-8 · Journal of Cosmetic Dermatology, 2017
- [Effect of a botanical cleansing lotion on skin sebum and erythema of the face: A randomized controlled blinded half-side comparison](https://pubmed.ncbi.nlm.nih.gov/30022595/) Willow bark extract · Journal of Cosmetic Dermatology, 2019
- [Anti-Inflammatory Effect of a Novel Topical Herbal Composition (VEL-091604) Consisting of Gentian Root, Licorice Root and Willow Bark Extract](https://pubmed.ncbi.nlm.nih.gov/30690691/) Willow bark extract · Planta Medica, 2019
- [An evaluation of the effect of a topical product containing salicin on the visible signs of human skin aging](https://pubmed.ncbi.nlm.nih.gov/20883292/) Willow bark extract · Journal of Cosmetic Dermatology, 2010
- [A retrospective assessment and comparison of the effectiveness of benzoyl peroxide; the combination of topical niacinamide, gallic acid, and lauric acid; and the combination of benzoyl peroxide and erythromycin in acne vulgaris](https://pubmed.ncbi.nlm.nih.gov/32390309/) Lauric acid · Dermatologic Therapy, 2020
- [The synergistic effect of retinyl propionate and hydroxypinacolone retinoate on skin aging](https://pubmed.ncbi.nlm.nih.gov/36762391/) Hydroxypinacolone retinoate · Journal of Cosmetic Dermatology, 2023
- [Administration of skin care regimens containing β-glucan for skin recovery after fractional laser therapy: A split-face, double-blinded, vehicle-controlled study](https://pubmed.ncbi.nlm.nih.gov/33128496/) Beta-glucan · Journal of Cosmetic Dermatology, 2021
- [Two-phase delivery using a horse oil and adenosine-loaded dissolving microneedle patch for skin barrier restoration, moisturization, and wrinkle improvement](https://pubmed.ncbi.nlm.nih.gov/30160014/) Adenosine · Journal of Cosmetic Dermatology, 2019
- [Effect of seasonal and geographical differences on skin and effect of treatment with an osmoprotectant: Sorbitol](https://pubmed.ncbi.nlm.nih.gov/23752031/) Sorbitol · Journal of Cosmetic Science, 2013
- [Clinical Development and Evaluation of a Multi-Component Dissolving Microneedle Patch for Skin Pigmentation Disorders](https://pubmed.ncbi.nlm.nih.gov/37571190/) 3-o-ethyl ascorbic acid · Polymers, 2023
- [Development of solid lipid microparticles (SLMs) containing asiatic acid for topical treatment of acne: Characterization, stability, in vitro and in vivo anti-acne assessment](https://pubmed.ncbi.nlm.nih.gov/38460769/) Centella asiatica leaf extract · International Journal of Pharmaceutics, 2024
- [Gene expression profile of human follicle dermal papilla cells in response to Camellia japonica phytoplacenta extract](https://pubmed.ncbi.nlm.nih.gov/33410284/) Camellia japonica flower extract · FEBS Open Bio, 2021
- [Supramolecular collagen nanoparticles for anti-wrinkle, skin whitening, and moisturizing effects](https://pubmed.ncbi.nlm.nih.gov/39383579/) Palmitoyl tripeptide-5 · Colloids and Surfaces. B, Biointerfaces, 2025
- [Comparison of topical purslane & topical 0.1% triamcinolone acetonide in the management of oral lichen planus - a double blinded clinical trial](https://pubmed.ncbi.nlm.nih.gov/37726676/) Portulaca oleracea extract · BMC Oral Health, 2023
- [Why is sodium cocoyl isethionate (SCI) mild to the skin barrier? - An in vitro investigation based on the relative sizes of the SCI micelles and the skin aqueous pores](https://pubmed.ncbi.nlm.nih.gov/17598025/) Sodium cocoyl isethionate · Journal of Cosmetic Science, 2007
- [Influence of vitamin E acetate on stratum corneum hydration](https://pubmed.ncbi.nlm.nih.gov/9706379/) Tocopheryl acetate vitamin e · Arzneimittel-Forschung, 1998
- [Anti-inflammatory and skin-hydrating properties of a dietary supplement and topical formulations containing oligomeric proanthocyanidins](https://pubmed.ncbi.nlm.nih.gov/17035721/) Grape seed extract · Skin Pharmacology and Physiology, 2007
- [Clinical study of Asian skin changes after application of a sunscreen formulation containing grape seed extract](https://pubmed.ncbi.nlm.nih.gov/35403355/) Grape seed extract · Journal of Cosmetic Dermatology, 2022
- [The anti wrinkle efficacy of synthetic hexapeptide (Argireline) in Chinese Subjects](https://pubmed.ncbi.nlm.nih.gov/23607739/) Acetyl hexapeptide-8 · Journal of Cosmetic and Laser Therapy, 2013
- [Propanediol (and) Caprylic Acid (and) Xylitol as a New Single Topical Active Ingredient against Acne: In Vitro and In Vivo Efficacy Assays](https://pubmed.ncbi.nlm.nih.gov/34771112/) Propanediol · Molecules, 2021
- [Evaluation of the Efficacy and Safety of a Panthenol-Enriched Mask for Skin Barrier Recovery After Facial Laser Treatment: Results of a Double-Blind Randomized Controlled Study](https://pubmed.ncbi.nlm.nih.gov/40613435/) Panthenol · Journal of Cosmetic Dermatology, 2025
- [Efficacy and Tolerability of Stable Hybrid Cooperative Complexes of High- and Low-Molecular Weight Hyaluronic Acid in Asian Patients: An Open-Label Study](https://pubmed.ncbi.nlm.nih.gov/40921777/) Hydrolyzed hyaluronic acid · Aesthetic Plastic Surgery, 2026
- [Functional properties and skin care effects of sodium trehalose sulfate](https://pubmed.ncbi.nlm.nih.gov/38606717/) Trehalose · Skin Research and Technology, 2024
- [Composition characterization and clinical efficacy study of a salmon egg extract](https://pubmed.ncbi.nlm.nih.gov/23738607/) Salmon egg extract · International Journal of Cosmetic Science, 2013
- [Translational Evaluation of a Disodium Adenosine Monophosphate (AMP2Na)-Based Topical Formulation for Physiology-Aligned Skin Rejuvenation: Integrated In Vitro, Ex Vivo, and Clinical Evidence](https://pubmed.ncbi.nlm.nih.gov/42278371/) Adenosine · International Journal of Molecular Sciences, 2026
- [Nanostructured Lipid Carrier Based Gel Containing α-Tocopherol and α-Tocopheryl Acetate for Synergistic Cutaneous Antiaging Efficacy](https://pubmed.ncbi.nlm.nih.gov/41309687/) Tocopheryl acetate vitamin e · Scientific Reports, 2025
- [Ethanolamines permeate slowly across human skin ex vivo, but cause severe skin irritation at low concentrations](https://pubmed.ncbi.nlm.nih.gov/31435711/) Ethanolamine · Archives of Toxicology, 2019
- [Portulaca oleracea extract relieves skin barrier damage induced by increased photosensitivity after GA peeling](https://pubmed.ncbi.nlm.nih.gov/35920724/) Portulaca oleracea extract · Cutaneous and Ocular Toxicology, 2022
- [Anti-Aging Efficacy of Low-Molecular-Weight Polydeoxyribonucleotide Derived from Paeonia lactiflora](https://pubmed.ncbi.nlm.nih.gov/41516097/) Sodium dna, Pdrn polydeoxyribonucleotide · International Journal of Molecular Sciences, 2025
- [Polydeoxyribonucleotide-spermidine nanoparticles: Preparation, characterization, and verification of skin anti-aging efficacy](https://pubmed.ncbi.nlm.nih.gov/40840755/) Sodium dna · International Journal of Biological Macromolecules, 2025
- [Safety assessment on comedogenicity of dermatological products containing d-alpha tocopheryl acetate in Asian subjects: A double-blind randomized controlled trial](https://pubmed.ncbi.nlm.nih.gov/34471722/) Tocopheryl acetate vitamin e · Contemporary Clinical Trials Communications, 2021
- [Efficacy of Topical Hydroxypinacolone Retinoate-Peptide Product Versus Fractional CO2 Laser in Facial Aging](https://pubmed.ncbi.nlm.nih.gov/39394831/) Hydroxypinacolone retinoate · Journal of Cosmetic Dermatology, 2025
- [A Randomized Controlled Trial of the Genistein Plus Bakuchiol and Vitamins (GEN+) Product for Male Facial Skin: Effects on Skin Appearance and Properties](https://pubmed.ncbi.nlm.nih.gov/41562471/) Bakuchiol · Skin Research and Technology, 2026
- [Low-temperature extracted Portulaca oleracea L. as a functional ingredient in facial masks for photorejuvenation of sensitive skin](https://pubmed.ncbi.nlm.nih.gov/41182319/) Portulaca oleracea extract · Cutaneous and Ocular Toxicology, 2025
- [The Therapeutic Effects of a Bentonite-Based Facial Mask With Alcea sulphurea Extract on Acne Severity and Patient Experience: Add-On Randomized Controlled Clinical Trial](https://pubmed.ncbi.nlm.nih.gov/41347526/) Bentonite · Journal of Cosmetic Dermatology, 2025
- [Split-face evaluation: Gluconolactone plus oxybrasion versus gluconolactone plus microneedling. The effects on skin parameters](https://pubmed.ncbi.nlm.nih.gov/37357656/) Gluconolactone · Skin Research and Technology, 2023
- [Efficacy of a Topical Formulation on Skin Hydration and Barrier Function in Individuals With Xerosis: A 28-Day Randomized, Split-Leg, Untreated-Controlled Trial](https://pubmed.ncbi.nlm.nih.gov/42108609/) Dipotassium glycyrrhizate · Journal of Cosmetic Dermatology, 2026
- [Prospective, Randomized, Double-Blind Assessment of Supramolecular Bakuchiol and Terminalia Chebula Extract for Facial Photoaging in Chinese Sensitive Skin Population](https://pubmed.ncbi.nlm.nih.gov/41424674/) Bakuchiol · Health Science Reports, 2025

## The brands

- Korean skincare: [Medicube](https://lovi.care/skincare/ae/brands/medicube)
- Canadian skincare: [Luna Nectar](https://lovi.care/skincare/ae/brands/luna-nectar)

## More comparisons

- [SKIN1004 vs Medicube](https://lovi.care/skincare/ae/compare/skin1004-vs-medicube)
- [SKIN1004 vs Luna Nectar](https://lovi.care/skincare/ae/compare/skin1004-vs-luna-nectar)
- [Anua vs Medicube](https://lovi.care/skincare/ae/compare/anua-vs-medicube)
- [Anua vs Luna Nectar](https://lovi.care/skincare/ae/compare/anua-vs-luna-nectar)
- [Medicube vs The Ordinary](https://lovi.care/skincare/ae/compare/medicube-vs-the-ordinary)
- [Medicube vs Beauty of Joseon](https://lovi.care/skincare/ae/compare/medicube-vs-beauty-of-joseon)
- [Medicube vs COSRX](https://lovi.care/skincare/ae/compare/medicube-vs-cosrx)
- [Medicube vs CeraVe](https://lovi.care/skincare/ae/compare/medicube-vs-cerave)
- [Medicube vs La Roche-Posay](https://lovi.care/skincare/ae/compare/medicube-vs-la-roche-posay)
- [Medicube vs Dr. Althea](https://lovi.care/skincare/ae/compare/medicube-vs-dr-althea)
- [Medicube vs Some By Mi](https://lovi.care/skincare/ae/compare/medicube-vs-some-by-mi)
- [Medicube vs Torriden](https://lovi.care/skincare/ae/compare/medicube-vs-torriden)
- [Medicube vs celimax](https://lovi.care/skincare/ae/compare/medicube-vs-celimax)
- [Medicube vs Purito](https://lovi.care/skincare/ae/compare/medicube-vs-purito)
- [Medicube vs Cetaphil](https://lovi.care/skincare/ae/compare/medicube-vs-cetaphil)
- [Medicube vs Paula's Choice](https://lovi.care/skincare/ae/compare/medicube-vs-paula-s-choice)
- [Medicube vs Neutrogena](https://lovi.care/skincare/ae/compare/medicube-vs-neutrogena)
- [Medicube vs Kiehl's](https://lovi.care/skincare/ae/compare/medicube-vs-kiehl-s)
- [Medicube vs Caudalie](https://lovi.care/skincare/ae/compare/medicube-vs-caudalie)
- [Medicube vs Dermalogica](https://lovi.care/skincare/ae/compare/medicube-vs-dermalogica)

## About the Lovi Fit

Lovi: Unbiased, science-based skincare AI trained on real user outcomes.

Lovi compares products by their fit scores, calculated from the full ingredient list with brand-independent rules its dermatologists and cosmetic chemists build and review, and personalizes every pick with AI trained on the real results of millions of users. Lovi trains its fit score models on a proprietary dataset built from more than 10,000 expert-labeled products and more than 100,000 simulated examples, following an internally consistent methodology presented at Cosmoprof, AMWC, and Skin of Color Update. Levels from best to worst: Superior, High, Average, Low, Caution, Warning.

Behind this comparison: Nadia Kapleva, MS (Co-founder, Medical Director); Alexey Shagraev, PhD (Co-founder, CEO and CTO); Dr. Sofía Perea Pérez, MD, MSc (Medical Board); Aishani Shah, MD (Medical Board); Asya Zubkova, MS (Medical Board); Hanna Kurets, MD (Medical Board, Medical Advisor); Elina Nazarenko, MD (Medical Board); Victoria Derkova, MS (Medical Board).

Page built Nov 8, 2026.

More from Lovi: https://lovi.care/skincare/llms.txt

## This page in other countries

- United States: https://lovi.care/skincare/compare/medicube-vs-luna-nectar
- United Kingdom: https://lovi.care/skincare/uk/compare/medicube-vs-luna-nectar
- Ireland: https://lovi.care/skincare/ie/compare/medicube-vs-luna-nectar
- Germany: https://lovi.care/skincare/de/compare/medicube-vs-luna-nectar
- France: https://lovi.care/skincare/fr/compare/medicube-vs-luna-nectar
- Italy: https://lovi.care/skincare/it/compare/medicube-vs-luna-nectar
- Netherlands: https://lovi.care/skincare/nl/compare/medicube-vs-luna-nectar
- Spain: https://lovi.care/skincare/es/compare/medicube-vs-luna-nectar
- Canada: https://lovi.care/skincare/ca/compare/medicube-vs-luna-nectar
- Australia: https://lovi.care/skincare/au/compare/medicube-vs-luna-nectar
- Singapore: https://lovi.care/skincare/sg/compare/medicube-vs-luna-nectar
- Saudi Arabia: https://lovi.care/skincare/sa/compare/medicube-vs-luna-nectar
- United Arab Emirates: https://lovi.care/skincare/ae/compare/medicube-vs-luna-nectar (this page)