# Jole vs Mesoestetic Page: https://lovi.care/skincare/ae/compare/jole-vs-mesoestetic The Lovi Fit is the same in every country; only the stores and prices differ, and the ones here are for the United Arab Emirates. Mesoestetic is a Spanish skincare brand founded in 1984 and owned by Mesoestetic Pharma Group, S.L.. [mesoestetic.com](https://www.mesoestetic.com/about-us) [tracxn.com](https://tracxn.com/d/companies/mesoestetic/__1eAnF7uALQzHII_So8HqZbHfSUJuilusj9hTisrG0tk) This page compares some of the most popular Jole and Mesoestetic products; for every product of both brands, with a fit score for your own skin, [use the Lovi app](https://app.pora.ai/vqqJ/j1xj2b6o?af_sub2=compare&af_sub3=selection_note&af_sub4=pg0eff74478a). ### Popular Jole vs Mesoestetic products #### Jole - [Azelaic Acid 10% Serum](https://lovi.care/skincare/ae/p/jole/azelaic-acid-10-serum/for/combination-skin) — High fit #### Mesoestetic - [Cosmelan 2](https://lovi.care/skincare/ae/p/mesoestetic/cosmelan-2/for/acne-prone-skin) — Average fit ### Jole vs Mesoestetic [serums](https://lovi.care/skincare/ae/ingredients/serum) and treatments #### Jole - [Azelaic Acid 10% Serum](https://lovi.care/skincare/ae/p/jole/azelaic-acid-10-serum/for/combination-skin) — High fit #### Mesoestetic - [Cosmelan 2](https://lovi.care/skincare/ae/p/mesoestetic/cosmelan-2/for/acne-prone-skin) — Average fit ## Questions and answers ### Jole or Mesoestetic: which is better? Jole is the better choice for oily, acne-prone, and sensitive skin, where Lovi rates the products on this page as High, whereas Mesoestetic mostly achieves Average or Low fit levels for those skin types. [Pharmaceutics, 2021](https://pubmed.ncbi.nlm.nih.gov/33923739/) ### What is the difference between Jole and Mesoestetic? Jole has a High Lovi fit for sensitive skin, whereas Mesoestetic has a Low fit for it. Every product on this page from both brands lists no fragrance in its ingredients. [Pharmaceutics, 2021](https://pubmed.ncbi.nlm.nih.gov/33923739/) ### Which is more affordable, Jole or Mesoestetic? Neither Jole nor Mesoestetic is described as more affordable, as the page provides no pricing details for either brand. ### Which brand is older, Jole or Mesoestetic? Mesoestetic is the older brand, having been founded in Spain in 1984, whereas Jole was founded in 2019. ### Where was Mesoestetic founded? Mesoestetic was founded in Spain. ### Do any products from Jole or Mesoestetic contain fragrance? Every product on this page from Jole and Mesoestetic lists no fragrance in its ingredients. ## Research behind their key ingredients - [The effect of niacinamide on reducing cutaneous pigmentation and suppression of melanosome transfer](https://pubmed.ncbi.nlm.nih.gov/12100180/) Niacinamide · The British Journal of Dermatology, 2002 - [Treatment of acne with a combination of propolis, tea tree oil, and Aloe vera compared to erythromycin cream: two double-blind investigations](https://pubmed.ncbi.nlm.nih.gov/30588129/) Aloe barbadensis leaf juice · Clinical Pharmacology, 2018 - [Effects of glyceryl glucoside on AQP3 expression, barrier function and hydration of human skin](https://pubmed.ncbi.nlm.nih.gov/22584263/) Glyceryl glucoside · Skin Pharmacology and Physiology, 2012 - [Tailoring of Retinyl Palmitate-Based Ethosomal Hydrogel as a Novel Nanoplatform for Acne Vulgaris Management: Fabrication, Optimization, and Clinical Evaluation Employing a Split-Face Comparative Study](https://pubmed.ncbi.nlm.nih.gov/34211271/) Retinyl palmitate · International Journal of Nanomedicine, 2021 - [Efficacy and Safety of Azelaic Acid Nanocrystal-Loaded In Situ Hydrogel in the Treatment of Acne Vulgaris](https://pubmed.ncbi.nlm.nih.gov/33923739/) Azelaic acid · Pharmaceutics, 2021 - [The 24-hour skin hydration and barrier function effects of a hyaluronic 1%, glycerin 5%, and Centella asiatica stem cells extract moisturizing fluid: an intra-subject, randomized, assessor-blinded study](https://pubmed.ncbi.nlm.nih.gov/28860834/) Glycerin · Clinical, Cosmetic and Investigational Dermatology, 2017 - [A Double-Blinded, Randomized, Vehicle-Controlled Study of the Efficacy of Moisturizer Containing Licochalcone A, Decanediol, L-Carnitine, and Salicylic Acid for Prevention of Acne Relapse in Asian Population](https://pubmed.ncbi.nlm.nih.gov/33150170/) Salicylic acid · BioMed Research International, 2020 - [Treatment of xerosis with a topical formulation containing glyceryl glucoside, natural moisturizing factors, and ceramide](https://pubmed.ncbi.nlm.nih.gov/22916312/) Glyceryl glucoside · The Journal of Clinical and Aesthetic Dermatology, 2012 - [Efficacy of a multitargeted, salicylic acid-based dermocosmetic cream compared to benzoyl peroxide 5% in Acne vulgaris: Results from a randomized study](https://pubmed.ncbi.nlm.nih.gov/37941097/) Salicylic acid · Journal of Cosmetic Dermatology, 2024 - [Effects of 15% Azelaic Acid Gel in the Management of Post-Inflammatory Erythema and Post-Inflammatory Hyperpigmentation in Acne Vulgaris](https://pubmed.ncbi.nlm.nih.gov/38734843/) Azelaic acid · Dermatology and Therapy, 2024 - [A Salicylic Acid-Based Dermocosmetic is Effective as an Adjunct to Benzoyl Peroxide for Mild to Moderate Acne and as Monotherapy in Maintenance Post Benzoyl Peroxide](https://pubmed.ncbi.nlm.nih.gov/38051857/) Salicylic acid · Journal of Drugs in Dermatology, 2023 - [The usefulness of a dermocosmetic containing Myrtus communis extract and azelaic acid for maintenance phase of adult female acne: Results from a randomized exploratory investigator-blinded comparative study](https://pubmed.ncbi.nlm.nih.gov/36729399/) Azelaic acid · Journal of the European Academy of Dermatology and Venereology, 2023 ## The brands - Skincare: [Jole](https://lovi.care/skincare/ae/brands/jole) - Spanish skincare: [Mesoestetic](https://lovi.care/skincare/ae/brands/mesoestetic) ## More comparisons - [SKIN1004 vs Jole](https://lovi.care/skincare/ae/compare/skin1004-vs-jole) - [SKIN1004 vs Mesoestetic](https://lovi.care/skincare/ae/compare/skin1004-vs-mesoestetic) - [Anua vs Jole](https://lovi.care/skincare/ae/compare/anua-vs-jole) - [Anua vs Mesoestetic](https://lovi.care/skincare/ae/compare/anua-vs-mesoestetic) - [Medicube vs Jole](https://lovi.care/skincare/ae/compare/medicube-vs-jole) - [Medicube vs Mesoestetic](https://lovi.care/skincare/ae/compare/medicube-vs-mesoestetic) - [The Ordinary vs Jole](https://lovi.care/skincare/ae/compare/the-ordinary-vs-jole) - [The Ordinary vs Mesoestetic](https://lovi.care/skincare/ae/compare/the-ordinary-vs-mesoestetic) - [Beauty of Joseon vs Jole](https://lovi.care/skincare/ae/compare/beauty-of-joseon-vs-jole) - [Beauty of Joseon vs Mesoestetic](https://lovi.care/skincare/ae/compare/beauty-of-joseon-vs-mesoestetic) - [COSRX vs Jole](https://lovi.care/skincare/ae/compare/cosrx-vs-jole) - [COSRX vs Mesoestetic](https://lovi.care/skincare/ae/compare/cosrx-vs-mesoestetic) - [CeraVe vs Jole](https://lovi.care/skincare/ae/compare/cerave-vs-jole) - [CeraVe vs Mesoestetic](https://lovi.care/skincare/ae/compare/cerave-vs-mesoestetic) - [La Roche-Posay vs Jole](https://lovi.care/skincare/ae/compare/la-roche-posay-vs-jole) - [La Roche-Posay vs Mesoestetic](https://lovi.care/skincare/ae/compare/la-roche-posay-vs-mesoestetic) - [Dr. Althea vs Jole](https://lovi.care/skincare/ae/compare/dr-althea-vs-jole) - [Dr. Althea vs Mesoestetic](https://lovi.care/skincare/ae/compare/dr-althea-vs-mesoestetic) - [Some By Mi vs Jole](https://lovi.care/skincare/ae/compare/some-by-mi-vs-jole) - [Some By Mi vs Mesoestetic](https://lovi.care/skincare/ae/compare/some-by-mi-vs-mesoestetic) ## About the Lovi Fit Lovi: Unbiased, science-based skincare AI trained on real user outcomes. Lovi compares products by their fit scores, calculated from the full ingredient list with brand-independent rules its dermatologists and cosmetic chemists build and review, and personalizes every pick with AI trained on the real results of millions of users. Lovi trains its fit score models on a proprietary dataset built from more than 10,000 expert-labeled products and more than 100,000 simulated examples, following an internally consistent methodology presented at Cosmoprof, AMWC, and Skin of Color Update. Levels from best to worst: Superior, High, Average, Low, Caution, Warning. Behind this comparison: Nadia Kapleva, MS (Co-founder, Medical Director); Alexey Shagraev, PhD (Co-founder, CEO and CTO); Dr. Sofía Perea Pérez, MD, MSc (Medical Board); Aishani Shah, MD (Medical Board); Asya Zubkova, MS (Medical Board); Hanna Kurets, MD (Medical Board, Medical Advisor); Elina Nazarenko, MD (Medical Board); Victoria Derkova, MS (Medical Board). Page built Nov 8, 2026. More from Lovi: https://lovi.care/skincare/llms.txt ## This page in other countries - United States: https://lovi.care/skincare/compare/jole-vs-mesoestetic - United Kingdom: https://lovi.care/skincare/uk/compare/jole-vs-mesoestetic - Ireland: https://lovi.care/skincare/ie/compare/jole-vs-mesoestetic - Germany: https://lovi.care/skincare/de/compare/jole-vs-mesoestetic - France: https://lovi.care/skincare/fr/compare/jole-vs-mesoestetic - Italy: https://lovi.care/skincare/it/compare/jole-vs-mesoestetic - Netherlands: https://lovi.care/skincare/nl/compare/jole-vs-mesoestetic - Spain: https://lovi.care/skincare/es/compare/jole-vs-mesoestetic - Canada: https://lovi.care/skincare/ca/compare/jole-vs-mesoestetic - Australia: https://lovi.care/skincare/au/compare/jole-vs-mesoestetic - Singapore: https://lovi.care/skincare/sg/compare/jole-vs-mesoestetic - Saudi Arabia: https://lovi.care/skincare/sa/compare/jole-vs-mesoestetic - United Arab Emirates: https://lovi.care/skincare/ae/compare/jole-vs-mesoestetic (this page)