# Clinique vs ISDIN

Page: https://lovi.care/skincare/ae/compare/clinique-vs-isdin

The Lovi Fit is the same in every country; only the stores and prices differ, and the ones here are for the United Arab Emirates.

Clinique and ISDIN are established transatlantic brands offering thoughtful selections of moisturizers, [serums](https://lovi.care/skincare/ae/ingredients/serum), and eye products. The American line incorporates hydrating [hyaluronic acid](https://lovi.care/skincare/ae/ingredients/hyaluronic-acid), nourishing [glycerin](https://lovi.care/skincare/ae/ingredients/glycerin), and invigorating [caffeine](https://lovi.care/skincare/ae/ingredients/caffeine) to best suit dry sensitive skin and oily skin. Conversely, the Spanish house relies on sophisticated formulas that cater primarily to acne-prone skin and combination skin. While both deliver reliable, gentle efficacy through daily use, they differ in their specific ingredient blends and targeted regional origins.

Clinique is an American skincare brand founded in 1968 and owned by The Estée Lauder Companies Inc..

[en.wikipedia.org](https://en.wikipedia.org/wiki/Clinique) [elcompanies.com](https://www.elcompanies.com/en/who-we-are/our-heritage) [businesswire.com](https://www.businesswire.com/news/home/20261019083802/en/The-Este-Lauder-Companies-Appoints-Krista-Lee-Berger-Senior-Vice-President-Global-Marketing-Clinique) [glossy.co](https://www.glossy.co/beauty/glossy-pop-newsletter-clinique-launches-first-ever-creator-led-campaign/)

ISDIN is a Spanish skincare brand founded in 1975 and owned by Puig.

[puig.com](https://www.puig.com/en/newsroom/new-chapter-for-Isdin-Puig-to-assume-full-ownership/) [beautymatter.com](https://beautymatter.com/articles/puig-to-take-full-ownership-of-isdin-in-1-39-billion-deal) [uploads.puig.com](https://uploads.puig.com/uploads/Puig_NP_Sept_14_EN_fc21e2f47a.pdf)

This page compares some of the most popular Clinique and ISDIN products; for every product of both brands, with a fit score for your own skin, [use the Lovi app](https://app.pora.ai/vqqJ/j1xj2b6o?af_sub2=compare&af_sub3=selection_note&af_sub4=pgb93ab5be67).

### Popular Clinique vs ISDIN products

#### ISDIN

- [Eryfotona Actinica](https://lovi.care/skincare/ae/p/isdin/eryfotona-actinica/for/mature-skin) — Superior fit
- [Fusion Water](https://lovi.care/skincare/ae/p/isdin/fusion-water/for/dry-sensitive-skin) — Superior fit — [AED 91.99 at Amazon](https://www.amazon.ae/dp/B00Z72U6JQ?tag=lovi00-21&linkCode=osi&th=1&psc=1)
- [K-Ox Eyes](https://lovi.care/skincare/ae/p/isdin/k-ox-eyes/for/dry-skin) — High fit
- [Hyaluronic Concentrate](https://lovi.care/skincare/ae/p/isdin/hyaluronic-concentrate/for/sensitive-skin) — High fit
- [Hyaluronic Moisture](https://lovi.care/skincare/ae/p/isdin/hyaluronic-moisture/for/dry-sensitive-skin) — Average fit
- [Flavo-C Serum](https://lovi.care/skincare/ae/p/isdin/flavo-c-serum/for/sensitive-skin) — High fit
- [Uradin Lotion 10](https://lovi.care/skincare/ae/p/isdin/uradin-lotion-10/for/dry-skin) — High fit
- [Retinal Intense Serum](https://lovi.care/skincare/ae/p/isdin/retinal-intense-serum/for/acne-prone-skin) — High fit — [AED 392.99 at Amazon](https://www.amazon.ae/dp/B0BD9DK6SC?tag=lovi00-21&linkCode=osi&th=1&psc=1)

#### Clinique

- [moisture surge](https://lovi.care/skincare/ae/p/clinique/moisture-surge/for/sensitive-skin) — High fit
- [Take The Day Off Cleansing Balm](https://lovi.care/skincare/ae/p/clinique/take-the-day-off-cleansing-balm/for/dry-skin) — Average fit — [AED 123.26 at Amazon](https://www.amazon.ae/dp/B0CBQPN4M9?tag=lovi00-21&linkCode=osi&th=1&psc=1)
- [Dramatically Different Moisturizing Lotion+](https://lovi.care/skincare/ae/p/clinique/dramatically-different-moisturizing-lotion/for/dry-skin) — Average fit — [AED 123.95 at Amazon](https://www.amazon.ae/dp/B00CVZ3NJ2?tag=lovi00-21&linkCode=osi&th=1&psc=1)
- [All About Eyes](https://lovi.care/skincare/ae/p/clinique/all-about-eyes/for/dry-skin) — High fit — [AED 164.29 at Amazon](https://www.amazon.ae/dp/B000OUTR32?tag=lovi00-21&linkCode=osi&th=1&psc=1)
- [Dramatically Different Moisturizing Gel](https://lovi.care/skincare/ae/p/clinique/dramatically-different-moisturizing-gel/for/oily-skin) — High fit — [AED 89.47 at Amazon](https://www.amazon.ae/dp/B003JRI3OG?tag=lovi00-21&linkCode=osi&th=1&psc=1)
- [Smart Clinical Repair Wrinkle Correcting Serum](https://lovi.care/skincare/ae/p/clinique/smart-clinical-repair-wrinkle-correcting-serum/for/mature-skin) — Average fit — [AED 297.75 at Amazon](https://www.amazon.ae/dp/B09FG8TJDD?tag=lovi00-21&linkCode=osi&th=1&psc=1)
- [Moisture Surge Overnight Mask](https://lovi.care/skincare/ae/p/clinique/moisture-surge-overnight-mask/for/dry-skin) — High fit — [AED 292.69 at Amazon](https://www.amazon.ae/dp/B00HSZRQQQ?tag=lovi00-21&linkCode=osi&th=1&psc=1)
- [Clarifying Lotion 2](https://lovi.care/skincare/ae/p/clinique/clarifying-lotion-2/for/oily-acne-prone-skin) — Average fit

## People Say

Clinique

ISDIN

- Hydration, plumping, and smoothing effects Mostly Mentioned Mostly Mentioned “Keeps my dry patches at bay all day — Clinique Dramatically Different Moisturizing Lotion+” “skin feels silky smooth — Clinique Smart Clinical Repair Wrinkle Correcting Serum” “Improved moisture and texture — ISDIN Hyaluronic Moisture” “skin looks smooth and healthy — ISDIN K-Ox Eyes”
- Lightweight and fast-absorbing texture Often Mentioned Mostly Mentioned “absorbs instantly — ISDIN Eryfotona Actinica” “ultra-light fluid product, which makes it super easy to apply — ISDIN Fusion Water” “Lightweight formula absorbs fast — ISDIN Hyaluronic Concentrate” “sinks in immediately — Clinique moisture surge”
- Gentle, non-irritating, and sensitive skin friendly Mostly Mentioned Often Mentioned “never irritated my eyes — Clinique All About Eyes” “No stinging eyes — Clinique Take The Day Off Cleansing Balm” “Sensitive/reactive skin tolerates — ISDIN Hyaluronic Moisture” “no excessive exfoliation — ISDIN Retinal Intense Serum”
- Good makeup base and compatibility Often Mentioned Often Mentioned “Melts waterproof mascara — Clinique Take The Day Off Cleansing Balm” “foundation glides on — Clinique moisture surge” “acts like a primer — ISDIN Eryfotona Actinica” “My skin felt sooo hydrated and looks so plump and dewey. — ISDIN Fusion Water”
- Morning glow and radiance Rarely Noted Often Mentioned “My hyperpigmentation has lightened and skin looks more even, even shines more. — ISDIN Flavo-C Serum” “skin looks immediately luminous — ISDIN K-Ox Eyes” “softening fine lines — ISDIN Retinal Intense Serum” “wake up glowing — Clinique Moisture Surge Overnight Mask”
- Controls oil and mattifies Sometimes Noted Sometimes Noted “keeps me matte — Clinique Dramatically Different Moisturizing Gel” “absorbs quickly — Clinique Moisture Surge Overnight Mask” “dries down matte — ISDIN Eryfotona Actinica” “Non-greasy — ISDIN Hyaluronic Moisture”
- High price point and cost concerns Often Mentioned Often Mentioned “jar is too small for the cost — Clinique moisture surge” “quite pricey — Clinique Smart Clinical Repair Wrinkle Correcting Serum” “very expensive — ISDIN Eryfotona Actinica” “My only wish is that ISDIN would make this product in a bigger size bottle. — ISDIN Fusion Water”
- Unpleasant scent or strong fragrance Sometimes Noted Often Mentioned “Smells like nail polish remover — Clinique Clarifying Lotion 2” “Smells like old oil — Clinique Take The Day Off Cleansing Balm” “Has a weird plastic-like smell — Clinique Dramatically Different Moisturizing Lotion+” “smell is overpowering — ISDIN Eryfotona Actinica”
- Causes breakouts or skin irritation Often Mentioned Rarely Noted “mild redness or irritation — ISDIN K-Ox Eyes” “I think the serum is too strong for my face as it has burned and left very rough and a peeling face. — ISDIN Flavo-C Serum” “slight peeling — ISDIN Retinal Intense Serum” “Woke up with whiteheads on my chin — Clinique Dramatically Different Moisturizing Lotion+”

### Clinique vs ISDIN routines for dry skin

#### ISDIN-focused routine

- Cleanser: [CeraVe Hydrating Facial Cleanser](https://lovi.care/skincare/ae/p/cerave/hydrating-facial-cleanser/for/dry-skin) — Superior fit — [AED 32.95 at Amazon](https://www.amazon.ae/dp/B07C5R51Q9?tag=lovi00-21&linkCode=osi&th=1&psc=1) — Morning · Evening · Once a week
- Moisturizer: [SKIN1004 Madagascar Centella Probio-Cica Enrich Cream](https://lovi.care/skincare/ae/p/skin1004/madagascar-centella-probio-cica-enrich-cream/for/dry-skin) — Superior fit — [AED 34.80 at Amazon](https://www.amazon.ae/dp/B0BTPGPK7H?tag=lovi00-21&linkCode=osi&th=1&psc=1) — Morning · Evening · Once a week
- SPF: [Fusion Water](https://lovi.care/skincare/ae/p/isdin/fusion-water/for/dry-skin) — Superior fit — [AED 91.99 at Amazon](https://www.amazon.ae/dp/B00Z72U6JQ?tag=lovi00-21&linkCode=osi&th=1&psc=1) — Morning
- Pre-Cleanser: [MISSHA Ultra Hyalon Cleansing Cream](https://lovi.care/skincare/ae/p/missha/ultra-hyalon-cleansing-cream/for/dry-skin) — Superior fit — [AED 35.29 at Amazon](https://www.amazon.ae/dp/B084Q16G8D?tag=lovi00-21&linkCode=osi&th=1&psc=1) — Evening · Once a week
- Cleansing Toner: [ROUND LAB 1025 Dokdo Cleansing Water](https://lovi.care/skincare/ae/p/round-lab/1025-dokdo-cleansing-water/for/dry-skin) — Superior fit — [AED 38.99 at Amazon](https://www.amazon.ae/dp/B0F625GKWW?tag=lovi00-21&linkCode=osi&th=1&psc=1) — Evening
- Serum or Treatment: [Retinal Intense Serum](https://lovi.care/skincare/ae/p/isdin/retinal-intense-serum/for/dry-skin) — Low fit — [AED 392.99 at Amazon](https://www.amazon.ae/dp/B0BD9DK6SC?tag=lovi00-21&linkCode=osi&th=1&psc=1) — Evening · Once a week
- Enzyme Powder: [VT Cica Mild Powder Wash](https://lovi.care/skincare/ae/p/vt/cica-mild-powder-wash/for/dry-skin) — High fit — [AED 47.62 at Amazon](https://www.amazon.ae/dp/B09BFHRCG1?tag=lovi00-21&linkCode=osi&th=1&psc=1) — Once a week
- Nourishing Mask: [Mediheal Watermide Essential Mask](https://lovi.care/skincare/ae/p/mediheal/watermide-essential-mask/for/dry-skin) — Superior fit — [AED 65.00 at Amazon](https://www.amazon.ae/dp/B0F6VHMDB5?tag=lovi00-21&linkCode=osi&th=1&psc=1) — Once a week

#### Clinique-focused routine

- Cleanser: [all about clean](https://lovi.care/skincare/ae/p/clinique/all-about-clean/for/dry-skin) — Warning fit — [AED 209.14 at Amazon](https://www.amazon.ae/dp/B004ZJQ5E2?tag=lovi00-21&linkCode=osi&th=1&psc=1) — Morning · Evening · Once a week
- Moisturizer: [Smart Clinical Repair Lifting Face + Neck Cream](https://lovi.care/skincare/ae/p/clinique/smart-clinical-repair-lifting-face-neck-cream/for/dry-skin) — High fit — [AED 553.77 at Amazon](https://www.amazon.ae/dp/B0CVB75YW4?tag=lovi00-21&linkCode=osi&th=1&psc=1) — Morning · Evening · Once a week
- SPF: [Dr.G Green Mild Up Sun+](https://lovi.care/skincare/ae/p/dr-g/green-mild-up-sun/for/dry-skin) — Superior fit — [AED 81.00 at Amazon](https://www.amazon.ae/dp/B0B15MPMPQ?tag=lovi00-21&linkCode=osi&th=1&psc=1) — Morning
- Pre-Cleanser: [Take The Day Off Cleansing Balm](https://lovi.care/skincare/ae/p/clinique/take-the-day-off-cleansing-balm/for/dry-skin) — Average fit — [AED 123.26 at Amazon](https://www.amazon.ae/dp/B0CBQPN4M9?tag=lovi00-21&linkCode=osi&th=1&psc=1) — Evening · Once a week
- Cleansing Toner: [Clarifying Lotion 2](https://lovi.care/skincare/ae/p/clinique/clarifying-lotion-2/for/dry-skin) — Caution fit — Evening
- Serum or Treatment: [Smart Clinical Repair Wrinkle Correcting Serum](https://lovi.care/skincare/ae/p/clinique/smart-clinical-repair-wrinkle-correcting-serum/for/dry-skin) — Average fit — [AED 297.75 at Amazon](https://www.amazon.ae/dp/B09FG8TJDD?tag=lovi00-21&linkCode=osi&th=1&psc=1) — Evening · Once a week
- Enzyme Powder: [VT Cica Mild Powder Wash](https://lovi.care/skincare/ae/p/vt/cica-mild-powder-wash/for/dry-skin) — High fit — [AED 47.62 at Amazon](https://www.amazon.ae/dp/B09BFHRCG1?tag=lovi00-21&linkCode=osi&th=1&psc=1) — Once a week
- Nourishing Mask: [Moisture Surge Overnight Mask](https://lovi.care/skincare/ae/p/clinique/moisture-surge-overnight-mask/for/dry-skin) — High fit — [AED 292.69 at Amazon](https://www.amazon.ae/dp/B00HSZRQQQ?tag=lovi00-21&linkCode=osi&th=1&psc=1) — Once a week

[Buy ISDIN routine · AED 739.63 · 88% fit](https://www.amazon.ae/gp/aws/cart/add.html?ASIN.1=B07C5R51Q9&Quantity.1=1&ASIN.2=B0BTPGPK7H&Quantity.2=1&ASIN.3=B00Z72U6JQ&Quantity.3=1&ASIN.4=B084Q16G8D&Quantity.4=1&ASIN.5=B0F625GKWW&Quantity.5=1&ASIN.6=B0BD9DK6SC&Quantity.6=1&ASIN.7=B09BFHRCG1&Quantity.7=1&ASIN.8=B0F6VHMDB5&Quantity.8=1&AssociateTag=lovi00-21) [Buy Clinique routine · AED 1,605.23 · 66% fit](https://www.amazon.ae/gp/aws/cart/add.html?ASIN.1=B004ZJQ5E2&Quantity.1=1&ASIN.2=B0CVB75YW4&Quantity.2=1&ASIN.3=B0B15MPMPQ&Quantity.3=1&ASIN.4=B0CBQPN4M9&Quantity.4=1&ASIN.5=B09FG8TJDD&Quantity.5=1&ASIN.6=B09BFHRCG1&Quantity.6=1&ASIN.7=B00HSZRQQQ&Quantity.7=1&AssociateTag=lovi00-21) [See multi-brand routine · 96% fit](https://lovi.care/skincare/ae/skin/dry-skin)

### Clinique vs ISDIN routines for oily skin

#### ISDIN-focused routine

- Cleanser: [CeraVe Foaming Facial Cleanser](https://lovi.care/skincare/ae/p/cerave/foaming-facial-cleanser/for/oily-skin) — Superior fit — [AED 49.95 at Amazon](https://www.amazon.ae/dp/B07C5XD33D?tag=lovi00-21&linkCode=osi&th=1&psc=1) — Morning · Evening · Once a week
- Hydrating Toner: [Some By Mi Snail Truecica Miracle Repair Toner](https://lovi.care/skincare/ae/p/some-by-mi/snail-truecica-miracle-repair-toner/for/oily-skin) — Superior fit — [AED 49.99 at Amazon](https://www.amazon.ae/dp/B08125WDCF?tag=lovi00-21&linkCode=osi&th=1&psc=1) — Morning · Once a week
- Moisturizer: [COSRX Oil-Free Ultra-Moisturizing Lotion (with Birch Sap)](https://lovi.care/skincare/ae/p/cosrx/oil-free-ultra-moisturizing-lotion-with-birch-sap/for/oily-skin) — Superior fit — [AED 33.40 at Amazon](https://www.amazon.ae/dp/B01CLTKI4A?tag=lovi00-21&linkCode=osi&th=1&psc=1) — Morning · Evening · Once a week
- SPF: [Fusion Water](https://lovi.care/skincare/ae/p/isdin/fusion-water/for/oily-skin) — High fit — [AED 91.99 at Amazon](https://www.amazon.ae/dp/B00Z72U6JQ?tag=lovi00-21&linkCode=osi&th=1&psc=1) — Morning
- Pre-Cleanser: [Shu Uemura Ultime8 Sublime Beauty Cleansing Oil](https://lovi.care/skincare/ae/p/shu-uemura/ultime8-sublime-beauty-cleansing-oil/for/oily-skin) — Superior fit — [AED 179.45 at Amazon](https://www.amazon.ae/dp/B0DNJKPSB8?tag=lovi00-21&linkCode=osi&th=1&psc=1) — Evening · Once a week
- Cleansing Toner: [Pixi Glow Tonic](https://lovi.care/skincare/ae/p/pixi/glow-tonic/for/oily-skin) — Superior fit — [AED 120.00 at Amazon](https://www.amazon.ae/dp/B07MVYKLXT?tag=lovi00-21&linkCode=osi&th=1&psc=1) — Evening
- Serum or Treatment: [Retinal Intense Serum](https://lovi.care/skincare/ae/p/isdin/retinal-intense-serum/for/oily-skin) — Average fit — [AED 392.99 at Amazon](https://www.amazon.ae/dp/B0BD9DK6SC?tag=lovi00-21&linkCode=osi&th=1&psc=1) — Evening · Once a week
- Enzyme Powder: [Dermalogica Daily Microfoliant](https://lovi.care/skincare/ae/p/dermalogica/daily-microfoliant/for/oily-skin) — Superior fit — [AED 101.09 at Amazon](https://www.amazon.ae/dp/B001VMJSCW?tag=lovi00-21&linkCode=osi&th=1&psc=1) — Once a week
- Cleansing Mask: [Revision Skincare Black Mask](https://lovi.care/skincare/ae/p/revision-skincare/black-mask/for/oily-skin) — Superior fit — [AED 204.00 at Amazon](https://www.amazon.ae/dp/B08NDPYZLR?tag=lovi00-21&linkCode=osi&th=1&psc=1) — Once a week

#### Clinique-focused routine

- Cleanser: [Redness Solutions Soothing Cleanser](https://lovi.care/skincare/ae/p/clinique/redness-solutions-soothing-cleanser/for/oily-skin) — Average fit — [AED 342.00 at Amazon](https://www.amazon.ae/dp/B01F2LBUBE?tag=lovi00-21&linkCode=osi&th=1&psc=1) — Morning · Evening · Once a week
- Hydrating Toner: [Some By Mi Snail Truecica Miracle Repair Toner](https://lovi.care/skincare/ae/p/some-by-mi/snail-truecica-miracle-repair-toner/for/oily-skin) — Superior fit — [AED 49.99 at Amazon](https://www.amazon.ae/dp/B08125WDCF?tag=lovi00-21&linkCode=osi&th=1&psc=1) — Morning · Once a week
- Moisturizer: [Dramatically Different Moisturizing Gel](https://lovi.care/skincare/ae/p/clinique/dramatically-different-moisturizing-gel/for/oily-skin) — High fit — [AED 89.47 at Amazon](https://www.amazon.ae/dp/B003JRI3OG?tag=lovi00-21&linkCode=osi&th=1&psc=1) — Morning · Evening · Once a week
- SPF: [d'Alba UVessence Mild Waterfull Sun Cream SPF 50](https://lovi.care/skincare/ae/p/d-alba/uvessence-mild-waterfull-sun-cream-spf-50/for/oily-skin) — Superior fit — [AED 92.70 at Amazon](https://www.amazon.ae/dp/B08MLDY1HL?tag=lovi00-21&linkCode=osi&th=1&psc=1) — Morning
- Pre-Cleanser: [Take The Day Off Cleansing Balm](https://lovi.care/skincare/ae/p/clinique/take-the-day-off-cleansing-balm/for/oily-skin) — Low fit — [AED 123.26 at Amazon](https://www.amazon.ae/dp/B0CBQPN4M9?tag=lovi00-21&linkCode=osi&th=1&psc=1) — Evening · Once a week
- Cleansing Toner: [Clarifying Lotion 2](https://lovi.care/skincare/ae/p/clinique/clarifying-lotion-2/for/oily-skin) — Average fit — Evening
- Serum or Treatment: [Even Better Clinical Dark Spot Corrector](https://lovi.care/skincare/ae/p/clinique/even-better-clinical-dark-spot-corrector/for/oily-skin) — High fit — Evening · Once a week
- Enzyme Powder: [Dermalogica Daily Microfoliant](https://lovi.care/skincare/ae/p/dermalogica/daily-microfoliant/for/oily-skin) — Superior fit — [AED 101.09 at Amazon](https://www.amazon.ae/dp/B001VMJSCW?tag=lovi00-21&linkCode=osi&th=1&psc=1) — Once a week
- Cleansing Mask: [Revision Skincare Black Mask](https://lovi.care/skincare/ae/p/revision-skincare/black-mask/for/oily-skin) — Superior fit — [AED 204.00 at Amazon](https://www.amazon.ae/dp/B08NDPYZLR?tag=lovi00-21&linkCode=osi&th=1&psc=1) — Once a week

[Buy ISDIN routine · AED 1,222.86 · 91% fit](https://www.amazon.ae/gp/aws/cart/add.html?ASIN.1=B07C5XD33D&Quantity.1=1&ASIN.2=B08125WDCF&Quantity.2=1&ASIN.3=B01CLTKI4A&Quantity.3=1&ASIN.4=B00Z72U6JQ&Quantity.4=1&ASIN.5=B0DNJKPSB8&Quantity.5=1&ASIN.6=B07MVYKLXT&Quantity.6=1&ASIN.7=B0BD9DK6SC&Quantity.7=1&ASIN.8=B001VMJSCW&Quantity.8=1&ASIN.9=B08NDPYZLR&Quantity.9=1&AssociateTag=lovi00-21) [Buy Clinique routine · AED 1,002.51 · 79% fit](https://www.amazon.ae/gp/aws/cart/add.html?ASIN.1=B01F2LBUBE&Quantity.1=1&ASIN.2=B08125WDCF&Quantity.2=1&ASIN.3=B003JRI3OG&Quantity.3=1&ASIN.4=B08MLDY1HL&Quantity.4=1&ASIN.5=B0CBQPN4M9&Quantity.5=1&ASIN.6=B001VMJSCW&Quantity.6=1&ASIN.7=B08NDPYZLR&Quantity.7=1&AssociateTag=lovi00-21) [See multi-brand routine · 97% fit](https://lovi.care/skincare/ae/skin/oily-skin)

### Clinique vs ISDIN routines for combination skin

#### ISDIN-focused routine

- Cleanser: [Fresh Soy Face Cleanser](https://lovi.care/skincare/ae/p/fresh/soy-face-cleanser/for/combination-skin) — Superior fit — [AED 84.53 at Amazon](https://www.amazon.ae/dp/B0013522FC?tag=lovi00-21&linkCode=osi&th=1&psc=1) — Morning · Evening · Once a week
- Hydrating Toner: [Paula's Choice Skin Balancing Pore-Reducing Toner](https://lovi.care/skincare/ae/p/paula-s-choice/skin-balancing-pore-reducing-toner/for/combination-skin) — Superior fit — [AED 145.00 at Amazon](https://www.amazon.ae/dp/B008EPPIQ4?tag=lovi00-21&linkCode=osi&th=1&psc=1) — Morning · Once a week
- Moisturizer: [COSRX Oil-Free Ultra-Moisturizing Lotion (with Birch Sap)](https://lovi.care/skincare/ae/p/cosrx/oil-free-ultra-moisturizing-lotion-with-birch-sap/for/combination-skin) — Superior fit — [AED 33.40 at Amazon](https://www.amazon.ae/dp/B01CLTKI4A?tag=lovi00-21&linkCode=osi&th=1&psc=1) — Morning · Evening · Once a week
- SPF: [Fusion Water](https://lovi.care/skincare/ae/p/isdin/fusion-water/for/combination-skin) — High fit — [AED 91.99 at Amazon](https://www.amazon.ae/dp/B00Z72U6JQ?tag=lovi00-21&linkCode=osi&th=1&psc=1) — Morning
- Pre-Cleanser: [Shu Uemura Ultime8 Sublime Beauty Cleansing Oil](https://lovi.care/skincare/ae/p/shu-uemura/ultime8-sublime-beauty-cleansing-oil/for/combination-skin) — Superior fit — [AED 179.45 at Amazon](https://www.amazon.ae/dp/B0DNJKPSB8?tag=lovi00-21&linkCode=osi&th=1&psc=1) — Evening · Once a week
- Cleansing Toner: [Medicube Zero Pore Pad 2.0](https://lovi.care/skincare/ae/p/medicube/zero-pore-pad-2-0/for/combination-skin) — Superior fit — [AED 53.12 at Amazon](https://www.amazon.ae/dp/B09V7Z4TJG?tag=lovi00-21&linkCode=osi&th=1&psc=1) — Evening
- Serum or Treatment: [Retinal Intense Serum](https://lovi.care/skincare/ae/p/isdin/retinal-intense-serum/for/combination-skin) — Average fit — [AED 392.99 at Amazon](https://www.amazon.ae/dp/B0BD9DK6SC?tag=lovi00-21&linkCode=osi&th=1&psc=1) — Evening · Once a week
- Enzyme Powder: [Dermalogica Daily Microfoliant](https://lovi.care/skincare/ae/p/dermalogica/daily-microfoliant/for/combination-skin) — Superior fit — [AED 101.09 at Amazon](https://www.amazon.ae/dp/B001VMJSCW?tag=lovi00-21&linkCode=osi&th=1&psc=1) — Once a week
- Cleansing Mask: [KORA Organics Turmeric Brightening & Exfoliating Mask](https://lovi.care/skincare/ae/p/kora-organics/turmeric-brightening-and-exfoliating-mask/for/combination-skin) — Superior fit — [AED 122.93 at Amazon](https://www.amazon.ae/dp/B09G7PCTTG?tag=lovi00-21&linkCode=osi&th=1&psc=1) — Once a week

#### Clinique-focused routine

- Cleanser: [all about clean](https://lovi.care/skincare/ae/p/clinique/all-about-clean/for/combination-skin) — Low fit — [AED 209.14 at Amazon](https://www.amazon.ae/dp/B004ZJQ5E2?tag=lovi00-21&linkCode=osi&th=1&psc=1) — Morning · Evening · Once a week
- Hydrating Toner: [Paula's Choice Skin Balancing Pore-Reducing Toner](https://lovi.care/skincare/ae/p/paula-s-choice/skin-balancing-pore-reducing-toner/for/combination-skin) — Superior fit — [AED 145.00 at Amazon](https://www.amazon.ae/dp/B008EPPIQ4?tag=lovi00-21&linkCode=osi&th=1&psc=1) — Morning · Once a week
- Moisturizer: [Dramatically Different Moisturizing Gel](https://lovi.care/skincare/ae/p/clinique/dramatically-different-moisturizing-gel/for/combination-skin) — Average fit — [AED 89.47 at Amazon](https://www.amazon.ae/dp/B003JRI3OG?tag=lovi00-21&linkCode=osi&th=1&psc=1) — Morning · Evening · Once a week
- Pre-Cleanser: [Take The Day Off Cleansing Balm](https://lovi.care/skincare/ae/p/clinique/take-the-day-off-cleansing-balm/for/combination-skin) — Low fit — [AED 123.26 at Amazon](https://www.amazon.ae/dp/B0CBQPN4M9?tag=lovi00-21&linkCode=osi&th=1&psc=1) — Evening · Once a week
- Cleansing Toner: [Clarifying Lotion 2](https://lovi.care/skincare/ae/p/clinique/clarifying-lotion-2/for/combination-skin) — Average fit — Evening
- Serum or Treatment: [Even Better Clinical Dark Spot Corrector](https://lovi.care/skincare/ae/p/clinique/even-better-clinical-dark-spot-corrector/for/combination-skin) — Average fit — Evening · Once a week
- Enzyme Powder: [Dermalogica Daily Microfoliant](https://lovi.care/skincare/ae/p/dermalogica/daily-microfoliant/for/combination-skin) — Superior fit — [AED 101.09 at Amazon](https://www.amazon.ae/dp/B001VMJSCW?tag=lovi00-21&linkCode=osi&th=1&psc=1) — Once a week
- Cleansing Mask: [KORA Organics Turmeric Brightening & Exfoliating Mask](https://lovi.care/skincare/ae/p/kora-organics/turmeric-brightening-and-exfoliating-mask/for/combination-skin) — Superior fit — [AED 122.93 at Amazon](https://www.amazon.ae/dp/B09G7PCTTG?tag=lovi00-21&linkCode=osi&th=1&psc=1) — Once a week

[Buy ISDIN routine · AED 1,204.50 · 92% fit](https://www.amazon.ae/gp/aws/cart/add.html?ASIN.1=B0013522FC&Quantity.1=1&ASIN.2=B008EPPIQ4&Quantity.2=1&ASIN.3=B01CLTKI4A&Quantity.3=1&ASIN.4=B00Z72U6JQ&Quantity.4=1&ASIN.5=B0DNJKPSB8&Quantity.5=1&ASIN.6=B09V7Z4TJG&Quantity.6=1&ASIN.7=B0BD9DK6SC&Quantity.7=1&ASIN.8=B001VMJSCW&Quantity.8=1&ASIN.9=B09G7PCTTG&Quantity.9=1&AssociateTag=lovi00-21) [Buy Clinique routine · AED 790.89 · 72% fit](https://www.amazon.ae/gp/aws/cart/add.html?ASIN.1=B004ZJQ5E2&Quantity.1=1&ASIN.2=B008EPPIQ4&Quantity.2=1&ASIN.3=B003JRI3OG&Quantity.3=1&ASIN.4=B0CBQPN4M9&Quantity.4=1&ASIN.5=B001VMJSCW&Quantity.5=1&ASIN.6=B09G7PCTTG&Quantity.6=1&AssociateTag=lovi00-21) [See multi-brand routine · 96% fit](https://lovi.care/skincare/ae/skin/combination-skin)

## Questions and answers

### Clinique or ISDIN: which is better?

ISDIN fits more skin types better on this page, offering superior routines for oily, combination, sensitive, acne-prone, mature, and dark spot prone skin. Clinique is a strong alternative that features no fragrance across the products on this page.

### What is the difference between Clinique and ISDIN?

Clinique features fragrance-free formulas with a strong focus on gentle moisturizers and cleansers, while ISDIN offers ultralight sunscreens and [serums](https://lovi.care/skincare/ae/ingredients/serum). Lovi shows that ISDIN generally achieves higher fit levels across most skin types compared to Clinique.

### Clinique or ISDIN for dry skin?

ISDIN is the better choice for dry skin, where Lovi rates its routine as High compared to Clinique's Average. ISDIN features ultralight sunscreens and lightweight moisturizers that help provide hydration without heavy textures.

### Clinique or ISDIN: which moisturizer is better?

ISDIN is a better fit for moisturizers on this page, as Lovi rates its overall routine fit for moisturizers higher across multiple skin types compared to Clinique. ISDIN also stands out for its lightweight and fast-absorbing texture, though it has a higher price point just like Clinique.

### Which is more affordable, Clinique or ISDIN?

Both Clinique and ISDIN have a high price point among the products on this page, so neither brand is more affordable.

### Which brand has a stronger fragrance, Clinique or ISDIN?

ISDIN has a stronger fragrance, with five out of eight products listing fragrance on this page. In contrast, every Clinique product on this page lists no fragrance in its ingredients.

### Clinique or ISDIN for oily skin?

For oily skin, Lovi finds that Clinique has a High fit while ISDIN provides a Superior fit. ISDIN stands out on this page for its ultralight, makeup-friendly sunscreens and lightweight moisturizers.

### Clinique or ISDIN for sensitive skin?

Lovi rates ISDIN as Superior and Clinique as High for sensitive skin. The products on this page for both brands are gentle and sensitive-skin friendly, but ISDIN has some fragranced items while every Clinique product on this page lists no fragrance.

### Clinique or ISDIN for acne-prone skin?

ISDIN is a better fit for acne-prone skin, with Lovi rating the brand's routine as Superior compared to Clinique's Average routine fit. Reviewers note that ISDIN offers lightweight moisturizers and ultralight sunscreens, though some report that the products may cause breakouts.

### Clinique or ISDIN for mature skin?

For mature skin, ISDIN offers a Superior Lovi fit level across the products on this page compared to Clinique, which reaches an Average fit level. Reviewers also note that ISDIN provides better morning glow and radiance, while Clinique avoids fragrance across its entire range.

### Clinique or ISDIN for skin with dark spots?

ISDIN is generally better suited for skin with dark spots, as Lovi rates its routine as Superior compared to Clinique's Average fit. Reviewers also note that ISDIN provides a better morning glow and radiance, while the products on this page for Clinique feature no fragrance.

## Research behind their key ingredients

- [Biological and pharmacological activities of squalene and related compounds: potential uses in cosmetic dermatology](https://pubmed.ncbi.nlm.nih.gov/19169201/) Squalene · Molecules, 2009
- [Skin delivery of epigallocatechin-3-gallate (EGCG) and hyaluronic acid loaded nano-transfersomes for antioxidant and anti-aging effects in UV radiation induced skin damage](https://pubmed.ncbi.nlm.nih.gov/28155509/) Antioxidants · Drug Delivery, 2017
- [Benefits of topical hyaluronic acid for skin quality and signs of skin aging: From literature review to clinical evidence](https://pubmed.ncbi.nlm.nih.gov/36200921/) Sodium hyaluronate, Hyaluronic acid · Dermatologic Therapy, 2022
- [Topical use of dexpanthenol in skin disorders](https://pubmed.ncbi.nlm.nih.gov/12113650/) Panthenol · American Journal of Clinical Dermatology, 2002
- [Caffeine's mechanisms of action and its cosmetic use](https://pubmed.ncbi.nlm.nih.gov/23075568/) Caffeine · Skin Pharmacology and Physiology, 2013
- [Topical application of glycolic acid suppresses the UVB induced IL-6, IL-8, MCP-1 and COX-2 inflammation by modulating NF-κB signaling pathway in keratinocytes and mice skin](https://pubmed.ncbi.nlm.nih.gov/28330776/) Micro-acid complex · Journal of Dermatological Science, 2017
- [Anti-aging and brightening effects of a topical treatment containing vitamin C, vitamin E, and raspberry leaf cell culture extract: A split-face, randomized controlled trial](https://pubmed.ncbi.nlm.nih.gov/31975502/) Ascorbic acid, Tocopherol · Journal of Cosmetic Dermatology, 2020
- [Protecting skin photoaging by NF-kappaB inhibitor](https://pubmed.ncbi.nlm.nih.gov/20540695/) Magnolia officinalis bark extract · Current Drug Metabolism, 2010
- [Effects of ascorbic acid on gingival melanin pigmentation in vitro and in vivo](https://pubmed.ncbi.nlm.nih.gov/19186973/) Ascorbyl glucoside · Journal of Periodontology, 2009
- [Prospective, randomized, double-blind assessment of topical bakuchiol and retinol for facial photoageing](https://pubmed.ncbi.nlm.nih.gov/29947134/) Bakuchiol · The British Journal of Dermatology, 2019
- [Vitamin C-squalene bioconjugate promotes epidermal thickening and collagen production in human skin](https://pubmed.ncbi.nlm.nih.gov/33037252/) Squalane · Scientific Reports, 2020
- [Treatment of acne with a combination of propolis, tea tree oil, and Aloe vera compared to erythromycin cream: two double-blind investigations](https://pubmed.ncbi.nlm.nih.gov/30588129/) Aloe barbadensis leaf water, Aloe barbadensis · Clinical Pharmacology, 2018
- [Urea: a comprehensive review of the clinical literature](https://pubmed.ncbi.nlm.nih.gov/24314769/) Urea · Dermatology Online Journal, 2013
- [Antiaging efficacy of melatonin-based day and night creams: a randomized, split-face, assessor-blinded proof-of-concept trial](https://pubmed.ncbi.nlm.nih.gov/29416368/) Melatonin · Clinical, Cosmetic and Investigational Dermatology, 2018
- [Effect of a topical antioxidant serum containing vitamin C, vitamin E, and ferulic acid after Q-switched 1064-nm Nd:YAG laser for treatment of environment-induced skin pigmentation](https://pubmed.ncbi.nlm.nih.gov/32052907/) Ascorbic acid · Journal of Cosmetic Dermatology, 2020
- [Green tea extract reduces induction of p53 and apoptosis in UVB-irradiated human skin independent of transcriptional controls](https://pubmed.ncbi.nlm.nih.gov/18631247/) Camellia sinensis leaf extract · Experimental Dermatology, 2009
- [Effect of 30% Supramolecular Salicylic Acid Peel on Skin Microbiota and Inflammation in Patients with Moderate-to-Severe Acne Vulgaris](https://pubmed.ncbi.nlm.nih.gov/36350527/) Micro-acid complex · Dermatology and Therapy, 2023
- [Systematic Study of Resveratrol Nanoliposomes Transdermal Delivery System for Enhancing Anti-Aging and Skin-Brightening Efficacy](https://pubmed.ncbi.nlm.nih.gov/36985709/) Polygonum cuspidatum root extract · Molecules, 2023
- [Role of Resveratrol in Regulating Cutaneous Functions](https://pubmed.ncbi.nlm.nih.gov/32382280/) Polygonum cuspidatum root extract · Evidence-based Complementary and Alternative Medicine, 2020
- [The 24-hour skin hydration and barrier function effects of a hyaluronic 1%, glycerin 5%, and Centella asiatica stem cells extract moisturizing fluid: an intra-subject, randomized, assessor-blinded study](https://pubmed.ncbi.nlm.nih.gov/28860834/) Glycerin · Clinical, Cosmetic and Investigational Dermatology, 2017
- [Randomized controlled study for the anti-aging effect of human adipocyte-derived mesenchymal stem cell media combined with niacinamide after laser therapy](https://pubmed.ncbi.nlm.nih.gov/33103316/) Niacinamide · Journal of Cosmetic Dermatology, 2021
- [The anti-wrinkle efficacy of argireline, a synthetic hexapeptide, in Chinese subjects: a randomized, placebo-controlled study](https://pubmed.ncbi.nlm.nih.gov/23417317/) Acetyl hexapeptide-8 · American Journal of Clinical Dermatology, 2013
- [A Double-Blinded, Randomized, Vehicle-Controlled Study of the Efficacy of Moisturizer Containing Licochalcone A, Decanediol, L-Carnitine, and Salicylic Acid for Prevention of Acne Relapse in Asian Population](https://pubmed.ncbi.nlm.nih.gov/33150170/) Salicylic acid · BioMed Research International, 2020
- [Stable Ozonides with Vitamin E Acetate versus Corticosteroid in the Treatment of Lichen Sclerosus in Foreskin: Evaluation of Effects on Inflammation](https://pubmed.ncbi.nlm.nih.gov/30991399/) Tocopheryl acetate · Urologia Internationalis, 2019
- [Magnolia ovovata extract and its active component magnolol prevent skin photoaging via inhibition of nuclear factor kappaB](https://pubmed.ncbi.nlm.nih.gov/17346696/) Magnolia officinalis bark extract · European Journal of Pharmacology, 2007
- [A new topical panthenol-containing emollient: Results from two randomized controlled studies assessing its skin moisturization and barrier restoration potential, and the effect on skin microflora](https://pubmed.ncbi.nlm.nih.gov/27425824/) Panthenol · The Journal of Dermatological Treatment, 2017
- [Senomorphic activity of a combination of niacinamide and hyaluronic acid: correlation with clinical improvement of skin aging](https://pubmed.ncbi.nlm.nih.gov/39009698/) Niacinamide · Scientific Reports, 2024
- [The efficacy of glycolic acid, salicylic acid, gluconolactone, and licochalcone A combined with 0.1% adapalene vs adapalene monotherapy in mild-to-moderate acne vulgaris: a double-blinded within-person comparative study](https://pubmed.ncbi.nlm.nih.gov/30858720/) Glycolic acid · Clinical, Cosmetic and Investigational Dermatology, 2019
- [High molecular compounds (polysaccharides and proanthocyanidins) from Hamamelis virginiana bark: influence on human skin keratinocyte proliferation and differentiation and influence on irritated skin](https://pubmed.ncbi.nlm.nih.gov/11684194/) Witch hazel extract · Phytochemistry, 2001
- [Anti-Wrinkle Efficacy of Cross-Linked Hyaluronic Acid-Based Microneedle Patch with Acetyl Hexapeptide-8 and Epidermal Growth Factor on Korean Skin](https://pubmed.ncbi.nlm.nih.gov/33911590/) Acetyl hexapeptide-8 · Annals of Dermatology, 2019
- [Efficacy of Probiotic Supplements and Topical Applications in the Treatment of Acne: A Scoping Review of Current Results](https://pubmed.ncbi.nlm.nih.gov/39810881/) Probiotic technology · Journal of Experimental Pharmacology, 2025
- [Efficacy of a multitargeted, salicylic acid-based dermocosmetic cream compared to benzoyl peroxide 5% in Acne vulgaris: Results from a randomized study](https://pubmed.ncbi.nlm.nih.gov/37941097/) Salicylic acid · Journal of Cosmetic Dermatology, 2024
- [Biomimetic hyaluronic acid-stabilized zinc oxide nanoparticles in acne treatment: A preclinical and clinical approach](https://pubmed.ncbi.nlm.nih.gov/40254135/) Zinc oxide · Journal of Controlled Release, 2025
- [Clay jojoba oil facial mask for lesioned skin and mild acne--results of a prospective, observational pilot study](https://pubmed.ncbi.nlm.nih.gov/22585103/) Jojoba seed oil · Forschende Komplementarmedizin, 2012
- [Evaluation of dermal extracellular matrix and epidermal-dermal junction modifications using matrix-assisted laser desorption/ionization mass spectrometric imaging, in vivo reflectance confocal microscopy, echography, and histology: effect of age and peptide applications](https://pubmed.ncbi.nlm.nih.gov/25817264/) Palmitoyl tripeptide-1, Palmitoyl tetrapeptide-7 · Journal of Cosmetic Dermatology, 2015
- [A Salicylic Acid-Based Dermocosmetic is Effective as an Adjunct to Benzoyl Peroxide for Mild to Moderate Acne and as Monotherapy in Maintenance Post Benzoyl Peroxide](https://pubmed.ncbi.nlm.nih.gov/38051857/) Salicylic acid · Journal of Drugs in Dermatology, 2023
- [Subclinical, non-erythematous irritation with an open assay model (washing): sodium lauryl sulfate (SLS) versus sodium laureth sulfate (SLES)](https://pubmed.ncbi.nlm.nih.gov/11278060/) Sodium laureth sulfate · Food and Chemical Toxicology, 2001
- [Topical application of jojoba (Simmondsia chinensis L.) wax enhances the synthesis of pro-collagen III and hyaluronic acid and reduces inflammation in the ex-vivo human skin organ culture model](https://pubmed.ncbi.nlm.nih.gov/38344180/) Jojoba seed oil · Frontiers in Pharmacology, 2024
- [Botulinum toxin injection as a single or combined treatment with non-cross-linked high molecular weight and low molecular weight hyaluronic acid gel for neck rejuvenation: A randomized clinical trial](https://pubmed.ncbi.nlm.nih.gov/35775872/) Hydrolyzed hyaluronic acid · Dermatologic Therapy, 2022
- [Safety assessment of cyclomethicone, cyclotetrasiloxane, cyclopentasiloxane, cyclohexasiloxane, and cycloheptasiloxane](https://pubmed.ncbi.nlm.nih.gov/22247236/) Cyclopentasiloxane · International Journal of Toxicology, 2011
- [The efficacy study of the combination of tripeptide-10-citrulline and acetyl hexapeptide-3. A prospective, randomized controlled study](https://pubmed.ncbi.nlm.nih.gov/28150423/) Acetyl hexapeptide-8 · Journal of Cosmetic Dermatology, 2017
- [Whitening effect of alpha-bisabolol in Asian women subjects](https://pubmed.ncbi.nlm.nih.gov/20642768/) Bisabolol · International Journal of Cosmetic Science, 2010
- [Antiacne and antiblotch activities of a formulated combination of Aloe barbadensis leaf powder, Garcinia mangostana peel extract, and Camellia sinensis leaf extract](https://pubmed.ncbi.nlm.nih.gov/31239743/) Camellia sinensis leaf extract · Clinical, Cosmetic and Investigational Dermatology, 2019
- [The synergistic effect of retinyl propionate and hydroxypinacolone retinoate on skin aging](https://pubmed.ncbi.nlm.nih.gov/36762391/) Hydroxypinacolone retinoate · Journal of Cosmetic Dermatology, 2023
- [Understanding Solar Skin Elastosis-Cause and Treatment](https://pubmed.ncbi.nlm.nih.gov/30052192/) Witch hazel extract · Journal of Cosmetic Science, 2018
- [Squalane as a Promising Agent Protecting UV-Induced Inhibition of Collagen Biosynthesis and Wound Healing in Human Dermal Fibroblast](https://pubmed.ncbi.nlm.nih.gov/40363772/) Squalane · Molecules, 2025
- [Epigallocatechin Gallate Enzymatic Alpha Glucosylation Potentiates Its Skin-Lightening Activity-Involvement of Skin Microbiota](https://pubmed.ncbi.nlm.nih.gov/39598779/) Camellia sinensis leaf extract · Molecules, 2024
- [Effects of Investigational Moisturizers on the Skin Barrier and Microbiome following Exposure to Environmental Aggressors: A Randomized Clinical Trial and Ex Vivo Analysis](https://pubmed.ncbi.nlm.nih.gov/37763018/) Yeast extract · Journal of Clinical Medicine, 2023
- [Comparison of methods for assessing photoprotection against ultraviolet A in vivo](https://pubmed.ncbi.nlm.nih.gov/3819071/) Butyl methoxydibenzoylmethane · Journal of the American Academy of Dermatology, 1987
- [Using ordered mesoporous silica SBA-15 to limit cutaneous penetration and transdermal permeation of organic UV filters](https://pubmed.ncbi.nlm.nih.gov/31437563/) Butyl methoxydibenzoylmethane · International Journal of Pharmaceutics, 2019
- [Influence of vitamin E acetate on stratum corneum hydration](https://pubmed.ncbi.nlm.nih.gov/9706379/) Tocopheryl acetate · Arzneimittel-Forschung, 1998
- [Clinical efficacy and safety of nano-microneedle-assisted phenylethyl resorcinol for the treatment of infraorbital dark circles](https://pubmed.ncbi.nlm.nih.gov/32783330/) Dimethoxytolyl propylresorcinol · Journal of Cosmetic Dermatology, 2021
- [Synergistic action of a triple peptide complex on an essential extra-cellular matrix protein exhibits significant anti-aging benefits](https://pubmed.ncbi.nlm.nih.gov/20618556/) Multi-peptides · Journal of Cosmetic Dermatology, 2010
- [Algae extract protection effect on oxidized protein level in human stratum corneum](https://pubmed.ncbi.nlm.nih.gov/15247018/) Algae extract · Annals of the New York Academy of Sciences, 2004
- [Topical Zinc Oxide Nanoparticle Formulations for Acne Vulgaris: A Systematic Review of Pre-Clinical and Early-Phase Clinical Evidence](https://pubmed.ncbi.nlm.nih.gov/41007718/) Zinc oxide · Biomedicines, 2025
- [Enhancing Photoprotection and Mitigating Ex Vivo Stratum Corneum Oxidative Stress: A Multifunctional Strategy Combining Rosmarinic Acid with UVB Filters](https://pubmed.ncbi.nlm.nih.gov/40227214/) Octocrylene · Antioxidants, 2025
- [Cucumber (Cucumis sativus L.) with heterologous poly-γ-glutamic acid has skin moisturizing, whitening and anti-wrinkle effects](https://pubmed.ncbi.nlm.nih.gov/38336313/) Cucumis sativus fruit extract · International Journal of Biological Macromolecules, 2024
- [Amended safety assessment of Sesamum indicum (sesame) seed oil, hydrogenated sesame seed oil, Sesamum indicum (sesame) oil unsaponifiables, and sodium sesameseedate](https://pubmed.ncbi.nlm.nih.gov/21772026/) Sesamum indicum oil · International Journal of Toxicology, 2011
- [The anti wrinkle efficacy of synthetic hexapeptide (Argireline) in Chinese Subjects](https://pubmed.ncbi.nlm.nih.gov/23607739/) Acetyl hexapeptide-8 · Journal of Cosmetic and Laser Therapy, 2013
- [Safety of a preservative system containing 1,2-hexanediol and caprylyl glycol](https://pubmed.ncbi.nlm.nih.gov/19514921/) Caprylyl glycol · Cutaneous and Ocular Toxicology, 2009
- [Evaluation of the Efficacy and Safety of a Panthenol-Enriched Mask for Skin Barrier Recovery After Facial Laser Treatment: Results of a Double-Blind Randomized Controlled Study](https://pubmed.ncbi.nlm.nih.gov/40613435/) Panthenol · Journal of Cosmetic Dermatology, 2025
- [TiO2-embedded mesoporous silica with lower porosity is beneficial to adsorb the pollutants and retard UV filter absorption: A possible application for outdoor skin protection](https://pubmed.ncbi.nlm.nih.gov/36455708/) Butyl methoxydibenzoylmethane · European Journal of Pharmaceutical Sciences, 2023
- [Efficacy and Tolerability of Stable Hybrid Cooperative Complexes of High- and Low-Molecular Weight Hyaluronic Acid in Asian Patients: An Open-Label Study](https://pubmed.ncbi.nlm.nih.gov/40921777/) Hydrolyzed hyaluronic acid · Aesthetic Plastic Surgery, 2026
- [Ginkgo biloba leaves extract's cosmeceutical evaluation: a preliminary assessments on human volunteers towards achieving improved skin condition and rejuvenation](https://pubmed.ncbi.nlm.nih.gov/37074796/) Ginkgo biloba leaf extract · Drug Development and Industrial Pharmacy, 2023
- [Effect of an Emollient Emulsion Containing 15.0% of Caprylic/Capric Triglyceride on the Urocanic Acid of the Stratum Corneum](https://pubmed.ncbi.nlm.nih.gov/37109405/) Caprylic capric triglyceride · Life, 2023
- [Functional properties and skin care effects of sodium trehalose sulfate](https://pubmed.ncbi.nlm.nih.gov/38606717/) Trehalose · Skin Research and Technology, 2024
- [A Double-Blind, 12-Week Study to Evaluate the Antiaging Efficacy of a Cream Containing the NFκB Inhibitor 4-Hexyl-1, 3-Phenylenediol and Ascorbic Acid-2 Glucoside in Adult Females](https://pubmed.ncbi.nlm.nih.gov/27272084/) Ascorbyl glucoside · Journal of Drugs in Dermatology, 2016
- [Nanostructured Lipid Carrier Based Gel Containing α-Tocopherol and α-Tocopheryl Acetate for Synergistic Cutaneous Antiaging Efficacy](https://pubmed.ncbi.nlm.nih.gov/41309687/) Tocopheryl acetate · Scientific Reports, 2025
- [Evaulation of irritation potential of surfactant mixtures](https://pubmed.ncbi.nlm.nih.gov/18503452/) Sodium laureth sulfate · International Journal of Cosmetic Science, 1999
- [Effects of a Postbiotic Saccharomyces and Lactobacillus Ferment Complex on the Scalp Microbiome of Chinese Women with Sensitive Scalp Syndrome](https://pubmed.ncbi.nlm.nih.gov/37767337/) Lactobacillus ferment · Clinical, Cosmetic and Investigational Dermatology, 2023
- [Nanocomplex of quaternized cyclodextrin grafted chitosan and hyaluronic acid for a skin delivery](https://pubmed.ncbi.nlm.nih.gov/36279763/) Hydrolyzed hyaluronic acid · Colloids and Surfaces. B, Biointerfaces, 2022
- [Safety assessment on comedogenicity of dermatological products containing d-alpha tocopheryl acetate in Asian subjects: A double-blind randomized controlled trial](https://pubmed.ncbi.nlm.nih.gov/34471722/) Tocopheryl acetate · Contemporary Clinical Trials Communications, 2021
- [The efficacy of enoxolone in reducing erythema and pain after laser treatment: A randomized split-face pilot study](https://pubmed.ncbi.nlm.nih.gov/38622995/) Glycyrrhetinic acid · Journal of Cosmetic Dermatology, 2024
- [Efficacy of Topical Hydroxypinacolone Retinoate-Peptide Product Versus Fractional CO2 Laser in Facial Aging](https://pubmed.ncbi.nlm.nih.gov/39394831/) Hydroxypinacolone retinoate · Journal of Cosmetic Dermatology, 2025
- [Treatment with Ascorbyl Glucoside-Arginine Complex Ameliorates Solar Lentigos](https://pubmed.ncbi.nlm.nih.gov/39769217/) Ascorbyl glucoside · International Journal of Molecular Sciences, 2024
- [Impact of Hydrocolloid Dressing and Moisturizing Cream as Facial Skin Protectants Among Health Care Workers](https://pubmed.ncbi.nlm.nih.gov/38771104/) Dimethicone · Military Medicine, 2024
- [Facial disbiosis and UV filters](https://pubmed.ncbi.nlm.nih.gov/39499337/) Ethylhexyl salicylate · Archives of Dermatological Research, 2024
- [The clinical efficacy of a new emulsion for acne and conspicuous facial pore amelioration](https://pubmed.ncbi.nlm.nih.gov/38140770/) Lens esculenta seed extract · Journal of Cosmetic Dermatology, 2024
- [The effect of a serum containing acetyl hexapeptide-8, dipeptide diaminobutyroyl benzylamide diacetate and gluconolactone on skin biomarkers, wrinkles and skin texture: Ex vivo and clinical studies](https://pubmed.ncbi.nlm.nih.gov/41668671/) Laminaria digitata extract · International Journal of Cosmetic Science, 2026
- [Efficacy and safety of combination cream of stimu-tex AS™ (spent grain wax, Argania Spinosa Kernel oil, Butyrospermum Parkii (shea butter) extract), and saccharide isomerate after fractional CO2 laser procedure: split-face, double blinded, randomized controlled trial](https://pubmed.ncbi.nlm.nih.gov/41134387/) Butyrospermum parkii butter shea butter, Shea butter · Lasers in Medical Science, 2025
- [Clinical Efficacy of Topical Ascorbic Acid 2-Glucoside in Enhancing Outcomes of Laser Gingival Depigmentation: A Randomized Controlled Trial](https://pubmed.ncbi.nlm.nih.gov/42147661/) Ascorbyl glucoside · Cureus, 2026
- [Impact of dermal emulsions containing diacyl phospholipids, mono acyl phospholipids, sodium lauryl ether sulfate and polysorbate 80 in combination with UVA irradiation on human skin physiology in vivo: A pilot study](https://pubmed.ncbi.nlm.nih.gov/42617898/) Sodium laureth sulfate · International Journal of Pharmaceutics, 2026
- [Simmondsia chinensis (jojoba) cake fermentation: A new, sustainable technology for advanced skin and scalp care ingredients](https://pubmed.ncbi.nlm.nih.gov/42698229/) Lactobacillus ferment · International Journal of Cosmetic Science, 2026
- [Efficacy of a Topical Formulation on Skin Hydration and Barrier Function in Individuals With Xerosis: A 28-Day Randomized, Split-Leg, Untreated-Controlled Trial](https://pubmed.ncbi.nlm.nih.gov/42108609/) Dipotassium glycyrrhizate · Journal of Cosmetic Dermatology, 2026
- [Retrospective Review of Dermal Safety Studies of Organic Sunscreens](https://pubmed.ncbi.nlm.nih.gov/40911743/) Ethylhexyl salicylate · Journal of Drugs in Dermatology, 2025
- [Targeting Circadian Rhythm for the Regulation of Skin Collagen Metabolism](https://pubmed.ncbi.nlm.nih.gov/41527525/) Palmitoyl tripeptide-1 · Journal of Cosmetic Dermatology, 2026
- [Mechanistic understanding and peptide ingredient screening for type III collagen via biological knowledge graph and molecular docking](https://pubmed.ncbi.nlm.nih.gov/42683869/) Palmitoyl tripeptide-1, Palmitoyl tetrapeptide-7 · International Journal of Cosmetic Science, 2026
- [Prospective, Randomized, Double-Blind Assessment of Supramolecular Bakuchiol and Terminalia Chebula Extract for Facial Photoaging in Chinese Sensitive Skin Population](https://pubmed.ncbi.nlm.nih.gov/41424674/) Bakuchiol · Health Science Reports, 2025

## The brands

- American skincare: [Clinique](https://lovi.care/skincare/ae/brands/clinique)
- Spanish skincare: [ISDIN](https://lovi.care/skincare/ae/brands/isdin)

## More comparisons

- [SKIN1004 vs Clinique](https://lovi.care/skincare/ae/compare/skin1004-vs-clinique)
- [SKIN1004 vs ISDIN](https://lovi.care/skincare/ae/compare/skin1004-vs-isdin)
- [Anua vs Clinique](https://lovi.care/skincare/ae/compare/anua-vs-clinique)
- [Anua vs ISDIN](https://lovi.care/skincare/ae/compare/anua-vs-isdin)
- [Medicube vs Clinique](https://lovi.care/skincare/ae/compare/medicube-vs-clinique)
- [Medicube vs ISDIN](https://lovi.care/skincare/ae/compare/medicube-vs-isdin)
- [The Ordinary vs Clinique](https://lovi.care/skincare/ae/compare/the-ordinary-vs-clinique)
- [The Ordinary vs ISDIN](https://lovi.care/skincare/ae/compare/the-ordinary-vs-isdin)
- [Beauty of Joseon vs Clinique](https://lovi.care/skincare/ae/compare/beauty-of-joseon-vs-clinique)
- [Beauty of Joseon vs ISDIN](https://lovi.care/skincare/ae/compare/beauty-of-joseon-vs-isdin)
- [COSRX vs Clinique](https://lovi.care/skincare/ae/compare/cosrx-vs-clinique)
- [COSRX vs ISDIN](https://lovi.care/skincare/ae/compare/cosrx-vs-isdin)
- [CeraVe vs Clinique](https://lovi.care/skincare/ae/compare/cerave-vs-clinique)
- [CeraVe vs ISDIN](https://lovi.care/skincare/ae/compare/cerave-vs-isdin)
- [La Roche-Posay vs Clinique](https://lovi.care/skincare/ae/compare/la-roche-posay-vs-clinique)
- [La Roche-Posay vs ISDIN](https://lovi.care/skincare/ae/compare/la-roche-posay-vs-isdin)
- [Dr. Althea vs Clinique](https://lovi.care/skincare/ae/compare/dr-althea-vs-clinique)
- [Dr. Althea vs ISDIN](https://lovi.care/skincare/ae/compare/dr-althea-vs-isdin)
- [Some By Mi vs Clinique](https://lovi.care/skincare/ae/compare/some-by-mi-vs-clinique)
- [Some By Mi vs ISDIN](https://lovi.care/skincare/ae/compare/some-by-mi-vs-isdin)

## About the Lovi Fit

Lovi: Unbiased, science-based skincare AI trained on real user outcomes.

Lovi compares products by their fit scores, calculated from the full ingredient list with brand-independent rules its dermatologists and cosmetic chemists build and review, and personalizes every pick with AI trained on the real results of millions of users. Lovi trains its fit score models on a proprietary dataset built from more than 10,000 expert-labeled products and more than 100,000 simulated examples, following an internally consistent methodology presented at Cosmoprof, AMWC, and Skin of Color Update. Levels from best to worst: Superior, High, Average, Low, Caution, Warning.

Behind this comparison: Nadia Kapleva, MS (Co-founder, Medical Director); Alexey Shagraev, PhD (Co-founder, CEO and CTO); Dr. Sofía Perea Pérez, MD, MSc (Medical Board); Aishani Shah, MD (Medical Board); Asya Zubkova, MS (Medical Board); Hanna Kurets, MD (Medical Board, Medical Advisor); Elina Nazarenko, MD (Medical Board); Victoria Derkova, MS (Medical Board).

Page built Nov 8, 2026.

More from Lovi: https://lovi.care/skincare/llms.txt

## This page in other countries

- United States: https://lovi.care/skincare/compare/clinique-vs-isdin
- United Kingdom: https://lovi.care/skincare/uk/compare/clinique-vs-isdin
- Ireland: https://lovi.care/skincare/ie/compare/clinique-vs-isdin
- Germany: https://lovi.care/skincare/de/compare/clinique-vs-isdin
- France: https://lovi.care/skincare/fr/compare/clinique-vs-isdin
- Italy: https://lovi.care/skincare/it/compare/clinique-vs-isdin
- Netherlands: https://lovi.care/skincare/nl/compare/clinique-vs-isdin
- Spain: https://lovi.care/skincare/es/compare/clinique-vs-isdin
- Canada: https://lovi.care/skincare/ca/compare/clinique-vs-isdin
- Australia: https://lovi.care/skincare/au/compare/clinique-vs-isdin
- Singapore: https://lovi.care/skincare/sg/compare/clinique-vs-isdin
- Saudi Arabia: https://lovi.care/skincare/sa/compare/clinique-vs-isdin
- United Arab Emirates: https://lovi.care/skincare/ae/compare/clinique-vs-isdin (this page)