# Medicube skincare

Page: https://lovi.care/skincare/ae/brands/medicube

The Lovi Fit is the same in every country; only the stores and prices differ, and the ones here are for the United Arab Emirates.

Medicube is a Korean skincare brand founded in 2016 and owned by APR Corp..

[medicubereviews.co.uk](https://medicubereviews.co.uk/medicube/story/) [glossy.co](https://www.glossy.co/beauty/medicubes-founder-on-the-products-and-people-that-fueled-the-k-beauty-brands-booming-year/)

Skincare enthusiasts revere Medicube for its curated selection of moisturizers, [serums](https://lovi.care/skincare/ae/ingredients/serum), toners, and masks, which thoughtfully incorporate ingredients like [niacinamide](https://lovi.care/skincare/ae/ingredients/niacinamide), [collagen](https://lovi.care/skincare/ae/ingredients/collagen), and [hyaluronic acid](https://lovi.care/skincare/ae/ingredients/hyaluronic-acid). Its products suit oily acne-prone skin and oily skin best by balancing excess sebum and hydration. For targeted concerns, the brand offers standout solutions such as the AGE-R Booster Gel for acne-prone skin, the Deep Peptide Radiance Mask for skin with dark spots, and the Deep Lifting Peptide Eye Cream for mature skin. Ultimately, its key ingredients work harmoniously, as niacinamide decreases hyperpigmentation and improves skin aging signs, collagen improves skin moisture elasticity and hydration, and hyaluronic acid lengthens botulinum toxin wrinkle effect.

[The British Journal of Dermatology, 2002](https://pubmed.ncbi.nlm.nih.gov/12100180/) [Dermatology Practical & Conceptual, 2022](https://pubmed.ncbi.nlm.nih.gov/35223163/) [Dermatologic Therapy, 2022](https://pubmed.ncbi.nlm.nih.gov/36200921/)

- [Niacinamide](https://lovi.care/skincare/ae/ingredients/niacinamide)
- [Collagen](https://lovi.care/skincare/ae/ingredients/collagen)
- [Hyaluronic acid](https://lovi.care/skincare/ae/ingredients/hyaluronic-acid)
- [Salicylic acid](https://lovi.care/skincare/ae/ingredients/salicylic-acid)
- [Centella asiatica](https://lovi.care/skincare/ae/ingredients/centella-asiatica)

This page covers some of the most popular Medicube products; for the whole Medicube range, with a fit score for every product, [use the Lovi app](https://app.pora.ai/vqqJ/j1xj2b6o?af_sub2=brand&af_sub3=selection_note&af_sub4=pg0103f033f2).

### Medicube moisturizers

#### Moisturizers

- [PDRN Pink Peptide Serum](https://lovi.care/skincare/ae/p/medicube/pdrn-pink-peptide-serum/for/mature-skin) — High fit — [AED 35.00 at Amazon](https://www.amazon.ae/dp/B0DBF65JYY?tag=lovi00-21&linkCode=osi&th=1&psc=1)
- [Collagen Jelly Cream](https://lovi.care/skincare/ae/p/medicube/collagen-jelly-cream/for/mature-skin) — Superior fit — [AED 37.99 at Amazon](https://www.amazon.ae/dp/B0CM2PPNMW?tag=lovi00-21&linkCode=osi&th=1&psc=1)
- [TRIPLE COLLAGEN CREAM](https://lovi.care/skincare/ae/p/medicube/triple-collagen-cream/for/mature-skin) — Average fit — [AED 45.99 at Amazon](https://www.amazon.ae/dp/B0BPXT3GBN?tag=lovi00-21&linkCode=osi&th=1&psc=1)
- [DEEP VITA-C CAPSULE CREAM](https://lovi.care/skincare/ae/p/medicube/deep-vita-c-capsule-cream/for/sensitive-skin) — Average fit — [AED 44.79 at Amazon](https://www.amazon.ae/dp/B0D2Z3GGCY?tag=lovi00-21&linkCode=osi&th=1&psc=1)
- [AGE-R Booster Gel](https://lovi.care/skincare/ae/p/medicube/age-r-booster-gel/for/mature-skin) — Superior fit — [AED 92.33 at Amazon](https://www.amazon.ae/dp/B0H4MHPRLG?tag=lovi00-21&linkCode=osi&th=1&psc=1)
- [Collagen Glow Bubble Serum](https://lovi.care/skincare/ae/p/medicube/collagen-glow-bubble-serum/for/dry-sensitive-skin) — High fit — [AED 35.00 at Amazon](https://www.amazon.ae/dp/B0FNZQG6HZ?tag=lovi00-21&linkCode=osi&th=1&psc=1)

### Medicube toners and essences

#### Toners and essences

- [Zero Pore Pad](https://lovi.care/skincare/ae/p/medicube/zero-pore-pad/for/oily-skin) — Superior fit — [AED 41.99 at Amazon](https://www.amazon.ae/dp/B0CW1KV8B6?tag=lovi00-21&linkCode=osi&th=1&psc=1)
- [Triple Collagen Toner](https://lovi.care/skincare/ae/p/medicube/triple-collagen-toner/for/mature-skin) — Superior fit — [AED 38.55 at Amazon](https://www.amazon.ae/dp/B0DW5CYSQ9?tag=lovi00-21&linkCode=osi&th=1&psc=1)
- [PDRN PINK CICA SOOTHING TONER](https://lovi.care/skincare/ae/p/medicube/pdrn-pink-cica-soothing-toner/for/acne-prone-skin) — High fit — [AED 37.99 at Amazon](https://www.amazon.ae/dp/B0DK3111J9?tag=lovi00-21&linkCode=osi&th=1&psc=1)
- [Red Toner](https://lovi.care/skincare/ae/p/medicube/red-toner/for/acne-prone-skin) — High fit — [AED 45.00 at Amazon](https://www.amazon.ae/dp/B0BQ6NBSWH?tag=lovi00-21&linkCode=osi&th=1&psc=1)
- [EXOSOME CICA CALMING PAD](https://lovi.care/skincare/ae/p/medicube/exosome-cica-calming-pad/for/acne-prone-skin) — Average fit

## People Say

★4.5

Overall rating based on 36.9k+ reviews

Reviewers most often praise Medicube for deep hydration, skin texture smoothing, and a radiant glass skin glow. The most common complaints are a sticky or heavy finish and strong fragrance or potential irritation.

### Highlights

- Deep hydration moisturizers Mostly Mentioned “skin feels bouncier and hydrated — PDRN Pink Peptide Serum” “Perfect for winter dryness — TRIPLE COLLAGEN CREAM” “revives my tired skin overnight — DEEP VITA-C CAPSULE CREAM”
- Radiant glow Often Mentioned “gave me instant glass skin — Collagen Jelly Cream” “woke up with glowing skin — Collagen Night Wrapping Mask” “glass skin — PDRN Pink Collagen Gel Mask”
- Smoother skin texture Often Mentioned “gives my skin a smooth, glass-like finish — Zero Pore Pad” “Skin is visibly smoother and refined — One Day Exosome Shot 2000” “skin feels smoother — PDRN Pink Peptide Serum”
- Soothing and gentle Sometimes Noted “calming the skin — Red Succinic Acid Peeling Pad” “Did not cause any irritation — Red Foam Cleanser” “immediate calming of sensitive skin — PDRN PINK CICA SOOTHING TONER”
- Hydration and plumping Sometimes Noted “woke up with baby soft skin — Collagen Jelly Cream” “skin feels plump and bouncy — Collagen Night Wrapping Mask” “fine lines vanished — PDRN Pink Collagen Gel Mask”
- Cooling jelly texture and sensation Sometimes Noted “feels amazing and cooling — Zero Pore Blackhead Mud Mask” “refreshing sensation — PDRN Pink Collagen Gel Mask” “feels cooling on application — Collagen Jelly Cream”
- Sticky residue Often Mentioned “hair sticks to my face — Collagen Jelly Cream” “feels way too sticky and tacky — DEEP VITA-C CAPSULE CREAM” “leaves a tacky film — Zero Pore Pad”
- Small quantity and pricing issues Often Mentioned “tube is tiny for the price — Collagen Night Wrapping Mask” “price is steep — PDRN Pink Collagen Gel Mask” “price is a bit steep — Red Succinic Acid Peeling Pad”
- Irritation and breakouts Sometimes Noted “caused redness and sensitivity — Zero Pore Pad” “woke up with whiteheads — Collagen Night Wrapping Mask” “small pimple appeared — PDRN Pink Peptide Serum”

Sources: lovi.care, amazon.com, medicube.us, oliveyoung.com, yesstyle.com, reddit.com, and more

### Medicube [serums](https://lovi.care/skincare/ae/ingredients/serum) and treatments

#### Serums and treatments

- [Red Succinic Acid Peeling Pad](https://lovi.care/skincare/ae/p/medicube/red-succinic-acid-peeling-pad/for/oily-acne-prone-skin) — Superior fit — [AED 43.99 at Amazon](https://www.amazon.ae/dp/B0CV7RX6ML?tag=lovi00-21&linkCode=osi&th=1&psc=1)
- [Deep Vita C Pad](https://lovi.care/skincare/ae/p/medicube/deep-vita-c-pad/for/oily-acne-prone-skin) — High fit — [AED 34.50 at Amazon](https://www.amazon.ae/dp/B0BPLYHDPG?tag=lovi00-21&linkCode=osi&th=1&psc=1)
- [One Day Exosome Shot 2000](https://lovi.care/skincare/ae/p/medicube/one-day-exosome-shot-2000/for/acne-prone-skin) — High fit — [AED 35.00 at Amazon](https://www.amazon.ae/dp/B0D16L5F2M?tag=lovi00-21&linkCode=osi&th=1&psc=1)
- [Zero Pore One Day Serum](https://lovi.care/skincare/ae/p/medicube/zero-pore-one-day-serum/for/dark-spots) — High fit — [AED 55.00 at Amazon](https://www.amazon.ae/dp/B09G267W27?tag=lovi00-21&linkCode=osi&th=1&psc=1)
- [Zero Exosome Shot](https://lovi.care/skincare/ae/p/medicube/zero-exosome-shot/for/oily-skin) — High fit — [AED 36.99 at Amazon](https://www.amazon.ae/dp/B0D137TMRB?tag=lovi00-21&linkCode=osi&th=1&psc=1)
- [Deep Vita A Retinol Serum](https://lovi.care/skincare/ae/p/medicube/deep-vita-a-retinol-serum/for/acne-prone-skin) — Average fit

### Other Medicube products

#### Other products

- [Collagen Night Wrapping Mask](https://lovi.care/skincare/ae/p/medicube/collagen-night-wrapping-mask/for/dry-skin) — High fit — [AED 35.00 at Amazon](https://www.amazon.ae/dp/B0BRMYHMS5?tag=lovi00-21&linkCode=osi&th=1&psc=1)
- [PDRN Pink Collagen Gel Mask](https://lovi.care/skincare/ae/p/medicube/pdrn-pink-collagen-gel-mask/for/dry-sensitive-skin) — High fit — [AED 35.00 at Amazon](https://www.amazon.ae/dp/B0DGTMR754?tag=lovi00-21&linkCode=osi&th=1&psc=1)
- [Zero Pore Blackhead Mud Mask](https://lovi.care/skincare/ae/p/medicube/zero-pore-blackhead-mud-mask/for/oily-acne-prone-skin) — High fit — [AED 49.00 at Amazon](https://www.amazon.ae/dp/B0D1G7XF9X?tag=lovi00-21&linkCode=osi&th=1&psc=1)
- [Deep Peptide Radiance Mask](https://lovi.care/skincare/ae/p/medicube/deep-peptide-radiance-mask/for/oily-acne-prone-skin) — Superior fit — [AED 49.99 at Amazon](https://www.amazon.ae/dp/B0DT6X9R7J?tag=lovi00-21&linkCode=osi&th=1&psc=1)
- [Zero Foam Cleanser](https://lovi.care/skincare/ae/p/medicube/zero-foam-cleanser/for/dry-skin) — Superior fit — [AED 38.99 at Amazon](https://www.amazon.ae/dp/B09C1B7BH5?tag=lovi00-21&linkCode=osi&th=1&psc=1)
- [Red Foam Cleanser](https://lovi.care/skincare/ae/p/medicube/red-foam-cleanser/for/combination-skin) — High fit — [AED 50.50 at Amazon](https://www.amazon.ae/dp/B073ZBXSJD?tag=lovi00-21&linkCode=osi&th=1&psc=1)
- [Deep Lifting Peptide Eye Cream](https://lovi.care/skincare/ae/p/medicube/deep-lifting-peptide-eye-cream/for/mature-skin) — Superior fit — [AED 80.52 at Amazon](https://www.amazon.ae/dp/B0G4VQ3Q5M?tag=lovi00-21&linkCode=osi&th=1&psc=1)
- [Deep Reviving Peptide Eye Cream](https://lovi.care/skincare/ae/p/medicube/deep-reviving-peptide-eye-cream/for/dark-spots) — High fit — [AED 64.36 at Amazon](https://www.amazon.ae/dp/B0G4VQ3Q5M?tag=lovi00-21&linkCode=osi&th=1&psc=1)

## Questions and answers

### Is Medicube good for oily skin?

Yes, Medicube is well suited for oily skin. Lovi rates the Medicube-focused routine High for oily skin. Reviewers often mention that these products help achieve a radiant glow and smoother skin texture while delivering deep hydration.

### Is Medicube worth it?

Yes, Medicube is generally worth considering because Lovi rates its brand-focused routines as High for all main skin types. Reviewers often mention deep hydration and smoother skin texture, though some note a sticky residue and pricing issues.

### What are Medicube's best products?

Medicube fits best for oily acne-prone skin, oily skin, and acne-prone skin. Lovi rates the brand-focused routines for these skin types as High.

### Which Medicube moisturizer is best for dry skin?

Lovi rates the AGE-R Booster Gel as the best moisturizer for dry skin with a Superior fit. The [Collagen](https://lovi.care/skincare/ae/ingredients/collagen) Jelly Cream and the [PDRN](https://lovi.care/skincare/ae/ingredients/pdrn) Pink Peptide [Serum](https://lovi.care/skincare/ae/ingredients/serum) follow with a High fit for dry skin.

### Does Medicube cause breakouts?

Medicube is unlikely to cause breakouts as a rule, though irritation and breakouts are sometimes noted by reviewers. Lovi rates the Medicube-focused routines High for acne-prone skin.

### Is Medicube fragrance-free?

Most of the Medicube products on this page are fragrance-free, as 23 out of 25 options list no fragrance. Only the Collagen Jelly Cream and the Deep Vita A [Retinol](https://lovi.care/skincare/ae/ingredients/retinol) Serum include fragrance.

### What are the key ingredients in Medicube products?

The key ingredients found across the Medicube products include [niacinamide](https://lovi.care/skincare/ae/ingredients/niacinamide), collagen, [hyaluronic acid](https://lovi.care/skincare/ae/ingredients/hyaluronic-acid), [salicylic acid](https://lovi.care/skincare/ae/ingredients/salicylic-acid), and [centella asiatica](https://lovi.care/skincare/ae/ingredients/centella-asiatica). Topical hyaluronic acid helps improve skin quality and signs of aging.

[Antioxidants, 2021](https://pubmed.ncbi.nlm.nih.gov/34439563/) [Dermatologic Therapy, 2022](https://pubmed.ncbi.nlm.nih.gov/36200921/)

### How do I build a Medicube skincare routine?

To build a Medicube routine for dry skin, start your morning with the Zero Foam Cleanser, Triple Collagen Toner, AGE-R Booster Gel, and SPF, followed in the evening by the Ultra Hyalon Cleansing Cream, Zero Foam Cleanser, Zero Pore Pad, One Day [Exosome](https://lovi.care/skincare/ae/ingredients/exosome) Shot 2000, and AGE-R Booster Gel. Once a week, add the Cica Mild Powder Wash and Deep Peptide Radiance Mask to this evening routine for extra care. Lovi rates the Medicube-focused routine High for dry skin.

### Where can I buy Medicube, and how much does it cost?

Medicube is available on Lovi with prices ranging from AED 34.50 to AED 92.33, with most products falling between AED 35.00 and AED 49.99.

### What are good alternatives to Medicube?

Good alternatives to Medicube include SKIN1004, Anua, Beauty of Joseon, COSRX, Dr. Althea, and Some By Mi. These similar brands also have dedicated pages on Lovi for shoppers to compare.

### Medicube vs SKIN1004: which is better?

Medicube and SKIN1004 both offer great options, but their fit varies depending on your skin type. For sensitive skin, Lovi rates the SKIN1004-focused routine as Superior while rating the Medicube-focused routine High. For dry, oily, combination, and acne-prone skin, Lovi rates both brand routines as High.

### Who owns Medicube, and where is it from?

Medicube is a Korean brand founded in 2016, owned by APR Corp..

[medicubereviews.co.uk](https://medicubereviews.co.uk/medicube/story/) [glossy.co](https://www.glossy.co/beauty/medicubes-founder-on-the-products-and-people-that-fueled-the-k-beauty-brands-booming-year/)

### Is Medicube cruelty-free?

PETA, Leaping Bunny, and Cruelty Free International, the registries Lovi checks, do not list Medicube as cruelty-free.

### Is Medicube good for dry skin?

Yes, Medicube is good for dry skin, and Lovi rates the Medicube-focused routine High for dry skin. Reviewers often mention deep hydration moisturizers, and the Medicube products on this page are mostly fragrance-free.

[Dermatologic Therapy, 2022](https://pubmed.ncbi.nlm.nih.gov/36200921/) [Dermatology Practical & Conceptual, 2022](https://pubmed.ncbi.nlm.nih.gov/35223163/)

### Which Medicube cleanser is best for oily skin?

The Red Foam Cleanser is the best option for oily skin, with the Zero Foam Cleanser also being a strong choice. Lovi rates both cleansers High for oily skin.

### Is Medicube good for sensitive skin?

Yes, Medicube is generally good for sensitive skin, as Lovi rates the Medicube-focused routine High for sensitive skin. Furthermore, 23 of the 25 Medicube products on this page list no fragrance, which helps reduce the risk of irritation for sensitive skin types.

### Is Medicube good for acne-prone skin?

Yes, Medicube is well suited for acne-prone skin and Lovi rates the brand-focused routines High for this skin type. The Medicube products on this page feature key ingredients like salicylic acid that help target breakouts.

### Is Medicube good for skin with dark spots?

Medicube is generally good for skin with dark spots because many of its targeted serums and creams feature brightening ingredients like niacinamide. Lovi rates the Zero Pore Pad High for skin with dark spots, and topical niacinamide helps reduce cutaneous pigmentation.

[The British Journal of Dermatology, 2002](https://pubmed.ncbi.nlm.nih.gov/12100180/) [Antioxidants, 2021](https://pubmed.ncbi.nlm.nih.gov/34439563/)

### Is Medicube good for mature skin?

Yes, Medicube is good for mature skin because Lovi rates the Medicube-focused routine High for dry skin and the brand offers targeted anti-aging products like the Collagen Jelly Cream and Deep Lifting Peptide Eye Cream. Retinol is known to help stimulate collagen accumulation in naturally aged human skin.

[The Journal of Investigative Dermatology, 2000](https://pubmed.ncbi.nlm.nih.gov/10692106/)

## Research behind Medicube's key ingredients

- [Vitamin A antagonizes decreased cell growth and elevated collagen-degrading matrix metalloproteinases and stimulates collagen accumulation in naturally aged human skin](https://pubmed.ncbi.nlm.nih.gov/10692106/) Retinol · The Journal of Investigative Dermatology, 2000
- [The effect of niacinamide on reducing cutaneous pigmentation and suppression of melanosome transfer](https://pubmed.ncbi.nlm.nih.gov/12100180/) Niacinamide · The British Journal of Dermatology, 2002
- [Mechanistic Basis and Clinical Evidence for the Applications of Nicotinamide (Niacinamide) to Control Skin Aging and Pigmentation](https://pubmed.ncbi.nlm.nih.gov/34439563/) Niacinamide · Antioxidants, 2021
- [Benefits of topical hyaluronic acid for skin quality and signs of skin aging: From literature review to clinical evidence](https://pubmed.ncbi.nlm.nih.gov/36200921/) Hyaluronic acid, Sodium hyaluronate · Dermatologic Therapy, 2022
- [Topical use of dexpanthenol in skin disorders](https://pubmed.ncbi.nlm.nih.gov/12113650/) Panthenol · American Journal of Clinical Dermatology, 2002
- [Efficacy of combined treatment with human adipose tissue stem cell-derived exosome-containing solution and microneedling for facial skin aging: A 12-week prospective, randomized, split-face study](https://pubmed.ncbi.nlm.nih.gov/37377400/) Exosome cica · Journal of Cosmetic Dermatology, 2023
- [Improvement of naturally aged skin with vitamin A (retinol)](https://pubmed.ncbi.nlm.nih.gov/17515510/) Retinol · Archives of Dermatology, 2007
- [Topical ascorbic acid on photoaged skin. Clinical, topographical and ultrastructural evaluation: double-blind study vs. placebo](https://pubmed.ncbi.nlm.nih.gov/12823436/) Vitamin c derivatives · Experimental Dermatology, 2003
- [Topical application of glycolic acid suppresses the UVB induced IL-6, IL-8, MCP-1 and COX-2 inflammation by modulating NF-κB signaling pathway in keratinocytes and mice skin](https://pubmed.ncbi.nlm.nih.gov/28330776/) Aha · Journal of Dermatological Science, 2017
- [Collagen Supplements for Aging and Wrinkles: A Paradigm Shift in the Fields of Dermatology and Cosmetics](https://pubmed.ncbi.nlm.nih.gov/35223163/) Collagen, Water-soluble collagen · Dermatology Practical & Conceptual, 2022
- [Topical palmitoyl pentapeptide provides improvement in photoaged human facial skin](https://pubmed.ncbi.nlm.nih.gov/18492182/) Palmitoyl pentapeptide-4 · International Journal of Cosmetic Science, 2005
- [Tea tree oil reduces histamine-induced skin inflammation](https://pubmed.ncbi.nlm.nih.gov/12452873/) Tree · The British Journal of Dermatology, 2002
- [Prospective, randomized, double-blind assessment of topical bakuchiol and retinol for facial photoageing](https://pubmed.ncbi.nlm.nih.gov/29947134/) Retinol · The British Journal of Dermatology, 2019
- [Apigenin inhibits UVA-induced cytotoxicity in vitro and prevents signs of skin aging in vivo](https://pubmed.ncbi.nlm.nih.gov/27279007/) Chamomilla recutita flower extract · International Journal of Molecular Medicine, 2016
- [Moisturizing and Antiinflammatory Properties of Cosmetic Formulations Containing Centella asiatica Extract](https://pubmed.ncbi.nlm.nih.gov/27168678/) Centella asiatica extract, Madecassoside · Indian Journal of Pharmaceutical Sciences, 2016
- [Use of Collagen in Cosmetic Products](https://pubmed.ncbi.nlm.nih.gov/38534748/) Collagen, Water-soluble collagen · Current Issues in Molecular Biology, 2024
- [Effect of Camellia japonica oil on human type I procollagen production and skin barrier function](https://pubmed.ncbi.nlm.nih.gov/17386986/) Camellia japonica flower extract · Journal of Ethnopharmacology, 2007
- [Ceramide 1 and ceramide 3 act synergistically on skin hydration and the transepidermal water loss of sodium lauryl sulfate-irritated skin](https://pubmed.ncbi.nlm.nih.gov/18717861/) Ceramide np · International Journal of Dermatology, 2008
- [Green tea extract reduces induction of p53 and apoptosis in UVB-irradiated human skin independent of transcriptional controls](https://pubmed.ncbi.nlm.nih.gov/18631247/) Camellia sinensis leaf extract · Experimental Dermatology, 2009
- [Clinical, biometric and structural evaluation of the long-term effects of a topical treatment with ascorbic acid and madecassoside in photoaged human skin](https://pubmed.ncbi.nlm.nih.gov/18503551/) Centella asiatica leaf extract · Experimental Dermatology, 2008
- [The 24-hour skin hydration and barrier function effects of a hyaluronic 1%, glycerin 5%, and Centella asiatica stem cells extract moisturizing fluid: an intra-subject, randomized, assessor-blinded study](https://pubmed.ncbi.nlm.nih.gov/28860834/) Glycerin · Clinical, Cosmetic and Investigational Dermatology, 2017
- [Randomized controlled study for the anti-aging effect of human adipocyte-derived mesenchymal stem cell media combined with niacinamide after laser therapy](https://pubmed.ncbi.nlm.nih.gov/33103316/) Niacinamide · Journal of Cosmetic Dermatology, 2021
- [The Effects of a Standardized Extract of Centella asiatica on Postlaser Resurfacing Wound Healing on the Face: A Split-Face, Double-Blind, Randomized, Placebo-Controlled Trial](https://pubmed.ncbi.nlm.nih.gov/32310680/) Madecassoside · Journal of Alternative and Complementary Medicine, 2020
- [The anti-wrinkle efficacy of argireline, a synthetic hexapeptide, in Chinese subjects: a randomized, placebo-controlled study](https://pubmed.ncbi.nlm.nih.gov/23417317/) Acetyl hexapeptide-8 · American Journal of Clinical Dermatology, 2013
- [Protective effects of Camellia japonica flower extract against urban air pollutants](https://pubmed.ncbi.nlm.nih.gov/30691451/) Camellia japonica flower extract · BMC Complementary and Alternative Medicine, 2019
- [Quaternized carboxymethyl chitosan/organic montmorillonite nanocomposite as a novel cosmetic ingredient against skin aging](https://pubmed.ncbi.nlm.nih.gov/28732847/) Bentonite · Carbohydrate Polymers, 2017
- [A Double-Blinded, Randomized, Vehicle-Controlled Study of the Efficacy of Moisturizer Containing Licochalcone A, Decanediol, L-Carnitine, and Salicylic Acid for Prevention of Acne Relapse in Asian Population](https://pubmed.ncbi.nlm.nih.gov/33150170/) Salicylic acid · BioMed Research International, 2020
- [Senomorphic activity of a combination of niacinamide and hyaluronic acid: correlation with clinical improvement of skin aging](https://pubmed.ncbi.nlm.nih.gov/39009698/) Niacinamide · Scientific Reports, 2024
- [A new topical panthenol-containing emollient: Results from two randomized controlled studies assessing its skin moisturization and barrier restoration potential, and the effect on skin microflora](https://pubmed.ncbi.nlm.nih.gov/27425824/) Panthenol · The Journal of Dermatological Treatment, 2017
- [Development and photoprotective effect of a sunscreen containing the antioxidants Spirulina and dimethylmethoxy chromanol on sun-induced skin damage](https://pubmed.ncbi.nlm.nih.gov/28341613/) Dimethylmethoxy chromanol · European Journal of Pharmaceutical Sciences, 2017
- [Microneedling by dermapen and glycolic acid peel for the treatment of acne scars: Comparative study](https://pubmed.ncbi.nlm.nih.gov/30548170/) Glycolic acid · Journal of Cosmetic Dermatology, 2019
- [Adenosine-loaded dissolving microneedle patches to improve skin wrinkles, dermal density, elasticity and hydration](https://pubmed.ncbi.nlm.nih.gov/29574973/) Adenosine · International Journal of Cosmetic Science, 2018
- [Hydrolyzed Collagen Induces an Anti-Inflammatory Response That Induces Proliferation of Skin Fibroblast and Keratinocytes](https://pubmed.ncbi.nlm.nih.gov/36501011/) Collagen extract · Nutrients, 2022
- [Efficacy of a topical gel containing chitosan, chlorhexidine, allantoin and dexpanthenol for pain and inflammation control after third molar surgery: A randomized and placebo-controlled clinical trial](https://pubmed.ncbi.nlm.nih.gov/32683390/) Allantoin · Medicina Oral, Patologia Oral Y Cirugia Bucal, 2020
- [Sunscreens and Cosmetic Formulations Containing Ascorbyl Tetraisopalmitate and Rice Peptides for the Improvement of Skin Photoaging: A Double-blind, Randomized Placebo-controlled Clinical Study](https://pubmed.ncbi.nlm.nih.gov/33529350/) Vitamin c derivatives · Photochemistry and Photobiology, 2021
- [The efficacy of glycolic acid, salicylic acid, gluconolactone, and licochalcone A combined with 0.1% adapalene vs adapalene monotherapy in mild-to-moderate acne vulgaris: a double-blinded within-person comparative study](https://pubmed.ncbi.nlm.nih.gov/30858720/) Glycolic acid, Gluconolactone · Clinical, Cosmetic and Investigational Dermatology, 2019
- [Systematic Study of Paeonol/Madecassoside Co-Delivery Nanoemulsion Transdermal Delivery System for Enhancing Barrier Repair and Anti-Inflammatory Efficacy](https://pubmed.ncbi.nlm.nih.gov/37446936/) Centella asiatica extract, Madecassoside, Centella asiatica leaf extract · Molecules, 2023
- [A comparative study of gluconolactone versus benzoyl peroxide in the treatment of acne](https://pubmed.ncbi.nlm.nih.gov/1303072/) Gluconolactone · The Australasian Journal of Dermatology, 1992
- [Anti-Wrinkle Efficacy of Cross-Linked Hyaluronic Acid-Based Microneedle Patch with Acetyl Hexapeptide-8 and Epidermal Growth Factor on Korean Skin](https://pubmed.ncbi.nlm.nih.gov/33911590/) Acetyl hexapeptide-8 · Annals of Dermatology, 2019
- [Efficacy of a multitargeted, salicylic acid-based dermocosmetic cream compared to benzoyl peroxide 5% in Acne vulgaris: Results from a randomized study](https://pubmed.ncbi.nlm.nih.gov/37941097/) Salicylic acid · Journal of Cosmetic Dermatology, 2024
- [A Lipid Mixture Enriched by Ceramide NP with Fatty Acids of Diverse Chain Lengths Contributes to Restore the Skin Barrier Function Impaired by Topical Corticosteroid](https://pubmed.ncbi.nlm.nih.gov/34348350/) Ceramide np · Skin Pharmacology and Physiology, 2022
- [Acid-base combination principles for preparation of anti-acne dissolving microneedles loaded with azelaic acid and matrine](https://pubmed.ncbi.nlm.nih.gov/34284096/) Sophora angustifolia root extract, Sophora flavescens root extract · European Journal of Pharmaceutical Sciences, 2021
- [A Salicylic Acid-Based Dermocosmetic is Effective as an Adjunct to Benzoyl Peroxide for Mild to Moderate Acne and as Monotherapy in Maintenance Post Benzoyl Peroxide](https://pubmed.ncbi.nlm.nih.gov/38051857/) Salicylic acid · Journal of Drugs in Dermatology, 2023
- [Comparison of skin calming effects of cosmetic products containing 4-t-butylcyclohexanol or acetyl dipeptide-1 cetyl ester on capsaicin-induced facial stinging in volunteers with sensitive skin](https://pubmed.ncbi.nlm.nih.gov/26805418/) Lifting peptide · Journal of the European Academy of Dermatology and Venereology, 2016
- [Efficacy and safety of moisturizer containing 5% panthenol, madecassoside, and copper-zinc-manganese versus 0.02% triamcinolone acetonide cream in decreasing adverse reaction and downtime after ablative fractional carbon dioxide laser resurfacing: A split-face, double-blinded, randomized, controlled trial](https://pubmed.ncbi.nlm.nih.gov/30945430/) Centella asiatica leaf extract · Journal of Cosmetic Dermatology, 2019
- [Stretchable skin hydrating PVB patches with controlled pores' size and shape for deliberate evening primrose oil spreading, transport and release](https://pubmed.ncbi.nlm.nih.gov/35929319/) Oenothera biennis flower extract · Biomaterials Advances, 2022
- [Effects of 1,3-propanediol associated, or not, with butylene glycol and/or glycerol on skin hydration and skin barrier function](https://pubmed.ncbi.nlm.nih.gov/37699769/) Propanediol · International Journal of Cosmetic Science, 2024
- [Antiacne and antiblotch activities of a formulated combination of Aloe barbadensis leaf powder, Garcinia mangostana peel extract, and Camellia sinensis leaf extract](https://pubmed.ncbi.nlm.nih.gov/31239743/) Camellia sinensis leaf extract · Clinical, Cosmetic and Investigational Dermatology, 2019
- [New clinical approach in facial mild-moderate acne: Re-stabilization of skin microbiota balance with a topical biotechnological phytocomplex](https://pubmed.ncbi.nlm.nih.gov/39205505/) Succinic acid · Journal of Cosmetic Dermatology, 2024
- [The efficacy study of the combination of tripeptide-10-citrulline and acetyl hexapeptide-3. A prospective, randomized controlled study](https://pubmed.ncbi.nlm.nih.gov/28150423/) Acetyl hexapeptide-8 · Journal of Cosmetic Dermatology, 2017
- [Effect of a botanical cleansing lotion on skin sebum and erythema of the face: A randomized controlled blinded half-side comparison](https://pubmed.ncbi.nlm.nih.gov/30022595/) Willow bark extract · Journal of Cosmetic Dermatology, 2019
- [Anti-Inflammatory Effect of a Novel Topical Herbal Composition (VEL-091604) Consisting of Gentian Root, Licorice Root and Willow Bark Extract](https://pubmed.ncbi.nlm.nih.gov/30690691/) Willow bark extract · Planta Medica, 2019
- [An evaluation of the effect of a topical product containing salicin on the visible signs of human skin aging](https://pubmed.ncbi.nlm.nih.gov/20883292/) Willow bark extract · Journal of Cosmetic Dermatology, 2010
- [A retrospective assessment and comparison of the effectiveness of benzoyl peroxide; the combination of topical niacinamide, gallic acid, and lauric acid; and the combination of benzoyl peroxide and erythromycin in acne vulgaris](https://pubmed.ncbi.nlm.nih.gov/32390309/) Lauric acid · Dermatologic Therapy, 2020
- [The synergistic effect of retinyl propionate and hydroxypinacolone retinoate on skin aging](https://pubmed.ncbi.nlm.nih.gov/36762391/) Hydroxypinacolone retinoate · Journal of Cosmetic Dermatology, 2023
- [Administration of skin care regimens containing β-glucan for skin recovery after fractional laser therapy: A split-face, double-blinded, vehicle-controlled study](https://pubmed.ncbi.nlm.nih.gov/33128496/) Beta-glucan · Journal of Cosmetic Dermatology, 2021
- [Two-phase delivery using a horse oil and adenosine-loaded dissolving microneedle patch for skin barrier restoration, moisturization, and wrinkle improvement](https://pubmed.ncbi.nlm.nih.gov/30160014/) Adenosine · Journal of Cosmetic Dermatology, 2019
- [Effect of seasonal and geographical differences on skin and effect of treatment with an osmoprotectant: Sorbitol](https://pubmed.ncbi.nlm.nih.gov/23752031/) Sorbitol · Journal of Cosmetic Science, 2013
- [Clinical Development and Evaluation of a Multi-Component Dissolving Microneedle Patch for Skin Pigmentation Disorders](https://pubmed.ncbi.nlm.nih.gov/37571190/) 3-o-ethyl ascorbic acid · Polymers, 2023
- [Development of solid lipid microparticles (SLMs) containing asiatic acid for topical treatment of acne: Characterization, stability, in vitro and in vivo anti-acne assessment](https://pubmed.ncbi.nlm.nih.gov/38460769/) Centella asiatica leaf extract · International Journal of Pharmaceutics, 2024
- [Gene expression profile of human follicle dermal papilla cells in response to Camellia japonica phytoplacenta extract](https://pubmed.ncbi.nlm.nih.gov/33410284/) Camellia japonica flower extract · FEBS Open Bio, 2021
- [Supramolecular collagen nanoparticles for anti-wrinkle, skin whitening, and moisturizing effects](https://pubmed.ncbi.nlm.nih.gov/39383579/) Palmitoyl tripeptide-5 · Colloids and Surfaces. B, Biointerfaces, 2025
- [Comparison of topical purslane & topical 0.1% triamcinolone acetonide in the management of oral lichen planus - a double blinded clinical trial](https://pubmed.ncbi.nlm.nih.gov/37726676/) Portulaca oleracea extract · BMC Oral Health, 2023
- [Why is sodium cocoyl isethionate (SCI) mild to the skin barrier? - An in vitro investigation based on the relative sizes of the SCI micelles and the skin aqueous pores](https://pubmed.ncbi.nlm.nih.gov/17598025/) Sodium cocoyl isethionate · Journal of Cosmetic Science, 2007
- [Influence of vitamin E acetate on stratum corneum hydration](https://pubmed.ncbi.nlm.nih.gov/9706379/) Tocopheryl acetate vitamin e · Arzneimittel-Forschung, 1998
- [Anti-inflammatory and skin-hydrating properties of a dietary supplement and topical formulations containing oligomeric proanthocyanidins](https://pubmed.ncbi.nlm.nih.gov/17035721/) Grape seed extract · Skin Pharmacology and Physiology, 2007
- [Clinical study of Asian skin changes after application of a sunscreen formulation containing grape seed extract](https://pubmed.ncbi.nlm.nih.gov/35403355/) Grape seed extract · Journal of Cosmetic Dermatology, 2022
- [The anti wrinkle efficacy of synthetic hexapeptide (Argireline) in Chinese Subjects](https://pubmed.ncbi.nlm.nih.gov/23607739/) Acetyl hexapeptide-8 · Journal of Cosmetic and Laser Therapy, 2013
- [Propanediol (and) Caprylic Acid (and) Xylitol as a New Single Topical Active Ingredient against Acne: In Vitro and In Vivo Efficacy Assays](https://pubmed.ncbi.nlm.nih.gov/34771112/) Propanediol · Molecules, 2021
- [Evaluation of the Efficacy and Safety of a Panthenol-Enriched Mask for Skin Barrier Recovery After Facial Laser Treatment: Results of a Double-Blind Randomized Controlled Study](https://pubmed.ncbi.nlm.nih.gov/40613435/) Panthenol · Journal of Cosmetic Dermatology, 2025
- [Efficacy and Tolerability of Stable Hybrid Cooperative Complexes of High- and Low-Molecular Weight Hyaluronic Acid in Asian Patients: An Open-Label Study](https://pubmed.ncbi.nlm.nih.gov/40921777/) Hydrolyzed hyaluronic acid · Aesthetic Plastic Surgery, 2026
- [Functional properties and skin care effects of sodium trehalose sulfate](https://pubmed.ncbi.nlm.nih.gov/38606717/) Trehalose · Skin Research and Technology, 2024
- [Composition characterization and clinical efficacy study of a salmon egg extract](https://pubmed.ncbi.nlm.nih.gov/23738607/) Salmon egg extract · International Journal of Cosmetic Science, 2013
- [Translational Evaluation of a Disodium Adenosine Monophosphate (AMP2Na)-Based Topical Formulation for Physiology-Aligned Skin Rejuvenation: Integrated In Vitro, Ex Vivo, and Clinical Evidence](https://pubmed.ncbi.nlm.nih.gov/42278371/) Adenosine · International Journal of Molecular Sciences, 2026
- [Nanostructured Lipid Carrier Based Gel Containing α-Tocopherol and α-Tocopheryl Acetate for Synergistic Cutaneous Antiaging Efficacy](https://pubmed.ncbi.nlm.nih.gov/41309687/) Tocopheryl acetate vitamin e · Scientific Reports, 2025
- [Ethanolamines permeate slowly across human skin ex vivo, but cause severe skin irritation at low concentrations](https://pubmed.ncbi.nlm.nih.gov/31435711/) Ethanolamine · Archives of Toxicology, 2019
- [Portulaca oleracea extract relieves skin barrier damage induced by increased photosensitivity after GA peeling](https://pubmed.ncbi.nlm.nih.gov/35920724/) Portulaca oleracea extract · Cutaneous and Ocular Toxicology, 2022
- [Anti-Aging Efficacy of Low-Molecular-Weight Polydeoxyribonucleotide Derived from Paeonia lactiflora](https://pubmed.ncbi.nlm.nih.gov/41516097/) Sodium dna, Pdrn polydeoxyribonucleotide · International Journal of Molecular Sciences, 2025
- [Polydeoxyribonucleotide-spermidine nanoparticles: Preparation, characterization, and verification of skin anti-aging efficacy](https://pubmed.ncbi.nlm.nih.gov/40840755/) Sodium dna · International Journal of Biological Macromolecules, 2025
- [Safety assessment on comedogenicity of dermatological products containing d-alpha tocopheryl acetate in Asian subjects: A double-blind randomized controlled trial](https://pubmed.ncbi.nlm.nih.gov/34471722/) Tocopheryl acetate vitamin e · Contemporary Clinical Trials Communications, 2021
- [Efficacy of Topical Hydroxypinacolone Retinoate-Peptide Product Versus Fractional CO2 Laser in Facial Aging](https://pubmed.ncbi.nlm.nih.gov/39394831/) Hydroxypinacolone retinoate · Journal of Cosmetic Dermatology, 2025
- [Low-temperature extracted Portulaca oleracea L. as a functional ingredient in facial masks for photorejuvenation of sensitive skin](https://pubmed.ncbi.nlm.nih.gov/41182319/) Portulaca oleracea extract · Cutaneous and Ocular Toxicology, 2025
- [The Therapeutic Effects of a Bentonite-Based Facial Mask With Alcea sulphurea Extract on Acne Severity and Patient Experience: Add-On Randomized Controlled Clinical Trial](https://pubmed.ncbi.nlm.nih.gov/41347526/) Bentonite · Journal of Cosmetic Dermatology, 2025
- [Split-face evaluation: Gluconolactone plus oxybrasion versus gluconolactone plus microneedling. The effects on skin parameters](https://pubmed.ncbi.nlm.nih.gov/37357656/) Gluconolactone · Skin Research and Technology, 2023
- [Efficacy of a Topical Formulation on Skin Hydration and Barrier Function in Individuals With Xerosis: A 28-Day Randomized, Split-Leg, Untreated-Controlled Trial](https://pubmed.ncbi.nlm.nih.gov/42108609/) Dipotassium glycyrrhizate · Journal of Cosmetic Dermatology, 2026

## Medicube routines

- 86% fit: [Routine for dry skin](https://lovi.care/skincare/ae/brands/medicube/skincare-routine/for/dry-skin)
- 87% fit: [Routine for oily skin](https://lovi.care/skincare/ae/brands/medicube/skincare-routine/for/oily-skin)
- 86% fit: [Routine for combination skin](https://lovi.care/skincare/ae/brands/medicube/skincare-routine/for/combination-skin)
- 86% fit: [Routine for sensitive skin](https://lovi.care/skincare/ae/brands/medicube/skincare-routine/for/sensitive-skin)
- 87% fit: [Routine for acne-prone skin](https://lovi.care/skincare/ae/brands/medicube/skincare-routine/for/acne-prone-skin)
- 86% fit: [Routine for mature skin](https://lovi.care/skincare/ae/brands/medicube/skincare-routine/for/mature-skin)
- 87% fit: [Routine for skin with dark spots](https://lovi.care/skincare/ae/brands/medicube/skincare-routine/for/dark-spots)
- 86% fit: [Routine for dry sensitive skin](https://lovi.care/skincare/ae/brands/medicube/skincare-routine/for/dry-sensitive-skin)
- 89% fit: [Routine for oily acne-prone skin](https://lovi.care/skincare/ae/brands/medicube/skincare-routine/for/oily-acne-prone-skin)

## Similar brands

- Korean skincare: [SKIN1004](https://lovi.care/skincare/ae/brands/skin1004)
- Korean skincare: [Anua](https://lovi.care/skincare/ae/brands/anua)
- Korean skincare: [Beauty of Joseon](https://lovi.care/skincare/ae/brands/beauty-of-joseon)
- Korean skincare: [COSRX](https://lovi.care/skincare/ae/brands/cosrx)
- Korean skincare: [Dr. Althea](https://lovi.care/skincare/ae/brands/dr-althea)
- Korean skincare: [Some By Mi](https://lovi.care/skincare/ae/brands/some-by-mi)
- Korean skincare: [Torriden](https://lovi.care/skincare/ae/brands/torriden)
- Korean skincare: [celimax](https://lovi.care/skincare/ae/brands/celimax)
- Korean skincare: [Purito](https://lovi.care/skincare/ae/brands/purito)
- Korean skincare: [ROUND LAB](https://lovi.care/skincare/ae/brands/round-lab)

## Compare Medicube

- [SKIN1004 vs Medicube](https://lovi.care/skincare/ae/compare/skin1004-vs-medicube)
- [Anua vs Medicube](https://lovi.care/skincare/ae/compare/anua-vs-medicube)
- [Medicube vs The Ordinary](https://lovi.care/skincare/ae/compare/medicube-vs-the-ordinary)
- [Medicube vs Beauty of Joseon](https://lovi.care/skincare/ae/compare/medicube-vs-beauty-of-joseon)
- [Medicube vs COSRX](https://lovi.care/skincare/ae/compare/medicube-vs-cosrx)
- [Medicube vs CeraVe](https://lovi.care/skincare/ae/compare/medicube-vs-cerave)
- [Medicube vs La Roche-Posay](https://lovi.care/skincare/ae/compare/medicube-vs-la-roche-posay)
- [Medicube vs Dr. Althea](https://lovi.care/skincare/ae/compare/medicube-vs-dr-althea)
- [Medicube vs Some By Mi](https://lovi.care/skincare/ae/compare/medicube-vs-some-by-mi)
- [Medicube vs Torriden](https://lovi.care/skincare/ae/compare/medicube-vs-torriden)
- [Medicube vs celimax](https://lovi.care/skincare/ae/compare/medicube-vs-celimax)
- [Medicube vs Purito](https://lovi.care/skincare/ae/compare/medicube-vs-purito)
- [Medicube vs Cetaphil](https://lovi.care/skincare/ae/compare/medicube-vs-cetaphil)
- [Medicube vs Paula's Choice](https://lovi.care/skincare/ae/compare/medicube-vs-paula-s-choice)
- [Medicube vs Neutrogena](https://lovi.care/skincare/ae/compare/medicube-vs-neutrogena)
- [Medicube vs Kiehl's](https://lovi.care/skincare/ae/compare/medicube-vs-kiehl-s)
- [Medicube vs Caudalie](https://lovi.care/skincare/ae/compare/medicube-vs-caudalie)
- [Medicube vs Dermalogica](https://lovi.care/skincare/ae/compare/medicube-vs-dermalogica)
- [Medicube vs Good Molecules](https://lovi.care/skincare/ae/compare/medicube-vs-good-molecules)
- [Medicube vs BYOMA](https://lovi.care/skincare/ae/compare/medicube-vs-byoma)

## Popular brands

- Canadian skincare: [The Ordinary](https://lovi.care/skincare/ae/brands/the-ordinary)
- American skincare: [CeraVe](https://lovi.care/skincare/ae/brands/cerave)
- French skincare: [La Roche-Posay](https://lovi.care/skincare/ae/brands/la-roche-posay)
- American skincare: [Cetaphil](https://lovi.care/skincare/ae/brands/cetaphil)
- American skincare: [Paula's Choice](https://lovi.care/skincare/ae/brands/paula-s-choice)
- American skincare: [Neutrogena](https://lovi.care/skincare/ae/brands/neutrogena)
- Korean skincare: [AXIS-Y](https://lovi.care/skincare/ae/brands/axis-y)
- American skincare: [Kiehl's](https://lovi.care/skincare/ae/brands/kiehl-s)
- Korean skincare: [d'Alba](https://lovi.care/skincare/ae/brands/d-alba)
- Korean skincare: [LANEIGE](https://lovi.care/skincare/ae/brands/laneige)
- Korean skincare: [Haruharu Wonder](https://lovi.care/skincare/ae/brands/haruharu-wonder)
- Korean skincare: [Pyunkang Yul](https://lovi.care/skincare/ae/brands/pyunkang-yul)
- Korean skincare: [innisfree](https://lovi.care/skincare/ae/brands/innisfree)
- French skincare: [Caudalie](https://lovi.care/skincare/ae/brands/caudalie)
- Korean skincare: [MISSHA](https://lovi.care/skincare/ae/brands/missha)
- American skincare: [Dermalogica](https://lovi.care/skincare/ae/brands/dermalogica)
- American skincare: [Good Molecules](https://lovi.care/skincare/ae/brands/good-molecules)
- Korean skincare: [Centellian24](https://lovi.care/skincare/ae/brands/centellian24)
- British skincare: [BYOMA](https://lovi.care/skincare/ae/brands/byoma)
- Korean skincare: [Biodance](https://lovi.care/skincare/ae/brands/biodance)

## About the Lovi Fit

Lovi: Unbiased, science-based skincare AI trained on real user outcomes.

Lovi rates every product from its full ingredient list with brand-independent rules its dermatologists and cosmetic chemists build and review, and personalizes every pick with AI trained on the real results of millions of users. Lovi trains its fit score models on a proprietary dataset built from more than 10,000 expert-labeled products and more than 100,000 simulated examples, following an internally consistent methodology presented at Cosmoprof, AMWC, and Skin of Color Update. Levels from best to worst: Superior, High, Average, Low, Caution, Warning.

Behind these ratings: Nadia Kapleva, MS (Co-founder, Medical Director); Alexey Shagraev, PhD (Co-founder, CEO and CTO); Dr. Sofía Perea Pérez, MD, MSc (Medical Board); Aishani Shah, MD (Medical Board); Asya Zubkova, MS (Medical Board); Hanna Kurets, MD (Medical Board, Medical Advisor); Elina Nazarenko, MD (Medical Board); Victoria Derkova, MS (Medical Board).

Page built Nov 8, 2026.

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